Rapid cure for diarrhea. Indications for the use of imodium - treatment of digestive disorders Diarrhea imodium does not help

Loose stools are formed under the influence of multiple adverse factors. Poor nutrition, stressful situations, allergic reactions, drugs, polluted environment, diseases of the digestive tract and other organs, bacteria can cause diarrhea. All of these factors contribute to the disruption of the digestive system and the appearance of diarrhea, to alleviate the symptoms of which there are various drugs with a quick effect. One of them is Imodium. The use of this drug allows you to reduce the number of bowel movements in a very short time and avoid many unpleasant consequences, such as dehydration, which is especially dangerous for children.

Description of the drug

Imodium is a medicine designed to combat the symptoms of diarrhea. A common form of release is lyophilized lozenges, chewable tablets (Imodium plus), capsules. Lyophilization is the drying of substances by rapid freezing and placement in a vacuum chamber. This method is used to increase the duration of storage of substances, in this case it is loperamide hydrochloride, which is the main active ingredient of Imodium. In addition to the main component, the composition of the drug includes additional substances:

• lactose;
• corn starch;
• talc;
• magnesium stearate;
• iron oxide;
• titanium dioxide;
• indigo carmine;
• aspartame;
• gelatin;
• sodium bicarbonate;
• mint or vanilla flavoring;
• simethicone.

Depending on the form of release, the composition of the excipients may differ slightly, but the dosage of loperamide hydrochloride remains unchanged - two milligrams in each tablet and capsule. In some cases, the medicine can be used in the form of drops or a solution, this form is especially relevant for children.

Pharmacological properties

Imodium, as indicated in the instructions for use, helps to reduce the contractile function of the intestine. Due to the binding of the active substance loperamide hydrochloride, which is part of the drug, with receptors located on the walls of the intestine, the synthesis of the hormones acetylcholine and prostaglandin is suppressed. This has a calming effect on the intestines and reduces peristalsis, helps to increase the time of passage of feces through the digestive tract and reduce the symptoms of diarrhea. The use of the drug provokes an increase in the tone of the rectum and anal sphincter, due to which loose stools are kept inside longer. In addition, loperamide hydrochloride has the property:

• reduce the secretion of mucus and its release into the intestinal lumen;
• stimulate the absorption capacity of the intestine, which increases the absorption of fluid into the blood and prevents dehydration, which often occurs with diarrhea;
• reduce pain and spasms.

Simethicone, which is part of the composition, relieves the symptoms that accompany diarrhea - flatulence, spasms. The medicine begins to act a maximum of an hour after ingestion. The duration of drug exposure is approximately six hours. It is excreted from the body in about a day with feces and urine.

What helps?

According to the indications for use, Imodium is used for:

• allergic diarrhea;
• psychogenic diarrhea;
• diarrhea caused by drugs;
• loose stools resulting from radiation, surgery;
• digestive disorders caused by changing climatic conditions, environmental conditions;
• food, alcohol and chemical poisoning, accompanied by diarrhea;
• diarrhea of ​​infectious, bacterial origin (as an aid);
• some diseases, a symptom of which is loose stools.

The drug is used for both acute and chronic diarrhea. Whatever the reason, the drug should not be taken if there is blood in the stool, which indicates internal bleeding that occurs with certain diseases in which the drug may be contraindicated.

Instructions for use, dosage

Due to the existing contraindications and age restrictions, you should consult a specialist before using the drug.

How to use

In the acute form of diarrhea, tablets for resorption, chewable tablets and capsules are prescribed in two pieces, which corresponds to four milligrams of loperamide - this is the initial dosage. Then take one tablet (capsule) after each bowel movement. The daily dosage of Imodium should not exceed eight tablets (capsules). In chronic diseases, the dosage is selected individually, usually no more than six tablets (capsules) per day, it all depends on the patient's condition. Treatment is continued until the number of bowel movements is reduced to two times a day.

The drug in liquid form is prescribed in the amount of 60 drops at the initial intake, then after each bowel movement, 30 drops. Daily dosage - no more than 180 drops during the day.

Lozenges are placed under the tongue, after dissolution they are not washed down. The capsules need to be taken with water. Chewable tablets are chewed and washed down with water. During treatment with this drug, the amount of fluid consumed should be increased to two to three liters per day. The average duration of treatment is three days, further use of the drug can lead to unpleasant consequences.

The drug should be discontinued if:

• within two days there is no improvement;
• bloody fecal discharge appeared;
• improvement is observed, the number of bowel movements does not exceed two times a day;
• no stool for twelve hours.

In case of infectious diarrhea, the drug is prescribed only in combination therapy with antibiotics. In the early days of infectious diseases or during intoxication, loose stools are not recommended to be eliminated with antidiarrheal agents, since bacteria and toxins leave the body with feces.

Use in pregnant and lactating women

The drug is strictly forbidden to use in the first three months of pregnancy and during lactation, since its effect is unsafe for the development of the child. In the second and third trimester, the use of the drug is permissible, but only in cases of urgent need. The dosage is set by the attending physician individually for each case.

Use for diarrhea in children

Children under the age of two years Imodium is contraindicated. For babies, its use is fraught with the development of paralysis of the intestinal muscles and swelling of the abdominal cavity, which is fatal. Therefore, in childhood, the drug should be used only under the supervision of a specialist. From the age of six, the use of lozenges is allowed, but drops and solution are the most convenient option. Capsules are not recommended for children under six years of age, chewable tablets are recommended from twelve years of age. But opinions differ on this point, as in some countries a different age threshold has been set for the use of Imodium in the treatment of childhood diseases. In some states, for example, in Australia, a ban on the use of funds in any form up to twelve years has been introduced.

Children's dosage:

1. Tablets and capsules are prescribed one at a time. The daily norm is no more than four tablets (capsules).
2. Drops - at the first dose they give 30, then 15 drops after each bowel movement. The maximum daily allowance is 120 drops.
3. The solution is prescribed 5 milliliters (one measuring cap) per 10 kilograms of the child's weight, no more than three times a day.

Children over the age of twelve are given the adult dosage. The duration of treatment is three days. If there is no positive result within two days, the drug should be discontinued.

Contraindications

It is excluded to use the medicine for children under two years of age, lactating women, in the first months of pregnancy, as well as for:

• intestinal obstruction, constipation;
• bloating;
• gastritis;
• Crohn's disease;
• intestinal adhesions;
• diverticulosis;
• hypersensitivity to the components of the drug;
• ulcerative and pseudomembranous colitis;
• phenylketonuria - a disease associated with impaired metabolism of phenylalanine (amino acid);
• the presence of blood in the stool;
• increase in body temperature;
• liver pathology.

Special care should be taken when treating loose stools caused by antibiotics, infectious diseases.

Side effects

If the dosage and instructions for the use of the drug are followed, unpleasant consequences are usually not observed. Overdose may cause:

• dizziness;
• headaches;
• malaise and weakness;
• sleep disorders;
• violations of coordination;
• thirst;
• nausea;
• vomiting;
• colic and spasms in the abdomen;
• flatulence;
• intestinal obstruction;
• urinary retention;
• skin rashes and other allergic reactions.

What is the price?

In different regions, the cost of the drug may differ. The price also depends on the form of the drug and the quantity in the package.

Approximate cost of 10 tablets:

• in Moscow - 246-370 rubles;
• in the Leningrad region - 265-311 rubles;
• in the Vladimir region - 238-312 rubles;
• in Volgograd - 278 rubles;
• in the Vologda region - 207-288 rubles;
• in the Voronezh region - 266-294 rubles;
• in the Ivanovo region - 216-314 rubles;
• in Kaliningrad - 298-304 rubles.

The approximate cost for 6 capsules is:

• in Moscow - 165-217 rubles;
• in the Leningrad region - 156-183 rubles;
• in Murmansk - 220-231 rubles.

Analogues

Analogues of the drug Imodium, similar in composition, are much cheaper. These include:

• Loperamide;
• Diara;
• Lopedium;
• Diarol;
• Superilop;
• Laremid;
• Enterobene;
• Loperacap;
• Stoperan.

The cheapest analogue is the drug Loperamide, its cost for 10 tablets is about 20 rubles, which is almost ten times cheaper than Imodium.

See also the collection -

- one of the most common ailments that periodically worries many people. Often diarrhea is not a symptom of any serious illness, but always causes significant inconvenience in everyday life.

Currently, there are many drugs for diarrhea, but most of them do not have a quick action. The effect of taking Imodium ® occurs within an hour after taking the first dose. It quickly and gently stops diarrhea.

Variety of causes of diarrhea

Chronic diseases of the rectum and colon, ulcers, colitis, gastritis.

Individual food intolerance to certain types of food.

Allergic reactions to food or medicines; menstruation in women.

Non-observance of norms and rules of individual hygiene.

The use of unboiled water or expired products.

Depending on the number and duration of episodes, diarrhea can range from acute, occurring suddenly and lasting no more than two weeks, to chronic, lasting two weeks or longer.

Imodium ® is used to stop both acute and chronic diarrhea.

Diarrhea not only causes a lot of inconvenience, but also poses a danger to the body: during an episode of diarrhea, water, salts and nutrients are lost, which leads to dehydration. Most harmful substances leave the body with the first stool, with each subsequent we lose the necessary trace elements. That is why it is important to stop diarrhea quickly!

Imodium ® is an important step in the treatment of diarrhea!

According to the recommendations of the World Organization of Gastroenterologists, the treatment of diarrhea should be carried out according to the following scheme: rehydration (replenishment of fluid losses), stopping diarrhea, and then restoring the intestinal microflora. As a means to stop diarrhea, Imodium ® is perfect: it not only lasts for an hour, but also comes in a convenient mint-flavored lozenge format that does not require drinking water.

In addition, Imodium ® can be taken by children from 6 years of age.

The drug is easily excreted from the gastrointestinal tract and acts within 6-8 hours.

The mechanism of action of Imodium ® helps not only to stop the intestinal peristalsis (wave-like contractions) accelerating during diarrhea, but also to optimize the process of fluid absorption and normalize the water-alkaline balance. Imodium® also increases the tone of the anal sphincter, reducing the urge to defecate, resulting in improved patient well-being.

An indispensable tool on the road and at home

If diarrhea started at home, you can always use a home first aid kit to quickly solve a delicate problem. However, if trouble caught you outside the home, for example, at work, on vacation, traveling or visiting, the need to stop diarrhea as quickly as possible increases repeatedly. To prevent such cases and quickly eliminate the consequences, we recommend that you always have Imodium ® at hand.

What is the difference between Imodium ® and other antidiarrheal drugs?

So, unlike probiotics, Imodium ® stops acute diarrhea, as it affects intestinal motility, while probiotics are designed to restore microflora after an episode of diarrhea.

Imodium ® stops diarrhea of ​​any origin, while antibacterial drugs are effective only in diarrhea caused by bacteria. For diarrhea caused by viruses, bacterial toxins, or non-infectious causes, antibacterial drugs do not work.

Imodium ® is an original drug developed by the famous Belgian scientist Paul Janssen. It has tremendous experience in the application and recognition of doctors and patients around the world.

In pharmacies, you can find other drugs with the same active ingredient. Often the price is suspiciously low. What's the secret? These are the so-called "generics" - drugs that try to copy the original product after the expiration of its patent protection. Formally, they have the same active ingredient, but the composition of the tablet differs significantly from the original by the presence of various impurities. The production of generics is tried to be as cheap as possible, while the quality of the product suffers. Innovative lozenges Imodium ® is produced in England, on modern innovative equipment, which ensures the highest quality. It is important to remember that studies on the effectiveness and safety were carried out specifically on Imodium ®, while the effectiveness and, most importantly, the safety of generics are practically not studied.

Imodium is a drug that comes in the form of capsules. In acute diarrhea, it is preferable to use Imodium in the form of lozenges. Thank you for explaining in detail how this Imodium works.

Imodium ® (lat. Imodium®) is an antidiarrheal drug. Imodium has two dosage forms: capsules and lozenges, also called lingual tablets. Imodium (lomeramide) is the drug of choice for the treatment of travelers' diarrhea. With secretory diarrhea, Imodium is also very effective due to its antisecretory opiate-like action.

How to take imodium: rules and warnings

The information presented in the section on medicines, methods of diagnosis and treatment is intended for medical professionals and is not an instruction for use. Imodium (lomeramide) is an effective remedy for acute non-infectious diarrhea, as well as mild to moderate infectious diarrhea.

Loperamide increases the tone of the anus sphincter, resulting in a decrease in the frequency and severity of the urge to defecate. Loperamide reduces mucus hypersecretion in the colon, in addition, it has an antisecretory effect, which is realized through both opioid and non-opioid receptors. Moreover, in these situations, it can exacerbate diarrhea. With infectious diarrhea, Imodium should be administered with caution, since the delay of the infectious agent in the body increases diarrhea and intoxication.

If a normal stool appears or if there is no stool for more than 12 hours, the drug is canceled (Instructions for use). The 2006 WHO Handbook Management of Diarrhea notes that imodium, as “…and other intestinal motility inhibitors, can reduce the frequency of defecation in adults. None of these drugs should be given to infants and children with diarrhea."

The composition of Imodium and its effect

Loperamide, which is part of the drug, has an effect an hour after application. The active substance of the drug (Loperamide) is easily excreted from the intestines, completely absorbed by the liver and excreted in the bile. In the USA in 1973 the drug was patented and it became known under the brand IMODIUM®. At the moment, it is the only drug containing Loperamide in this form (among its analogues).

Learn more about IMODIUM®, its principle of action and the history of the drug in the world and in Ukraine. IMODIUM® should be used for the treatment of acute and chronic diarrhea and in cases of traveler's diarrhea. If symptoms persist for more than 48 hours, a doctor should be consulted. To establish a diagnosis and prescribe a course of treatment, it is necessary to consult a doctor.

Indications for use:

The action of imodium is associated with the effect on the nerve cells of its active component - loperamide. Fecal masses are retained in the intestines, while partial reabsorption of water and salts into the blood occurs and dehydration is prevented.

For all chronic diseases and conditions of the intestine, Imodium can only be prescribed by a doctor who selects an individual dose of the drug and monitors the patient's condition. If the patient has signs of an overdose of the drug, intestinal obstruction or intestinal infection, imodium is canceled. Some resort to the emergency help of highly advertised drugs, such as the popular Imodium.

A spoiled and contaminated product, in which pathogenic microorganisms and dangerous toxins are present, is eaten by an adult or a child. In the stomach, under the action of hydrochloric acid, microbes can die, but the toxins are not neutralized, unfortunately.

The pharmaceutical industry has been manufacturing Imodium for over 30 years. It comes in capsules that need to be swallowed and washed down. Another more convenient form, especially on the road, is rounded tablets of white color and mint flavor, they must be sucked.

Briefly about food poisoning and intestinal infections

The drug relieves pain associated with spasms in the intestines. The medicine begins to act within half an hour. Imodium has no effect on pathogenic bacteria. With diarrhea, microbes and their toxic products are in the intestines.

You don’t have to grab Imodium yet, if diarrhea happened due to taking antibiotics - then complications may arise against the background of dysbacteriosis. Imodium or its cheaper synonym Loperamide are often found in home or camping first aid kits. They are used by many because they are easy to use. People think that these drugs can be resorted to in any case of diarrhea without fear.

Now it’s clear that you still need to drink something else from intestinal microbes, or even Imodium in extreme cases, if you really go in transport. This drug acts on the muscles of the intestine and slows down the movement of its contents. What medicine will quickly and effectively help against diarrhea? In this article you can read the instructions for the use of the drug against indigestion.

This is a fairly well-known and effective antidiarrheal drug, which has found its wide application around the world. The manufacturer of this drug is Janssen.

However, as for newborns, this drug paralyzes the intestinal muscles in them. As a result, most children die. A similar tragedy happened in Pakistan. Many experts argue that children's Imodium should be discontinued in pharmacies.

That's when many people pull out of their purse pre-stored Imodium tablets or other drugs, its analogues. But in such situations, the use of Imodium is still undesirable. To prevent this from happening, it is better to take imodium as prescribed by a doctor, despite the fact that this drug is sold in a pharmacy without a prescription.

Imodium: instructions for use

How does Imodium work?

In the classification of medicines, the drug belongs to the antidiarrheal group. Loperamide reduces the motor activity of the muscular wall of the intestine and increases the tone of the anal sphincter (the muscle ring that locks the rectum), which slows down the passage of contents through the intestinal tube. The action occurs within half an hour after administration and lasts up to 6 hours.

Dosage of the drug

Imodium is available in capsules and tablets of 2 mg. Adults and children over 12 years of age are recommended to start with diarrhea at 4 mg, followed by another 2 mg after each episode of diarrhea. The maximum allowable dose for adults is 16 mg per day, and for children - 6 mg per 20 kg of body weight up to 16 mg. In children, it is allowed for use from 4 years in the following dose:

• from 4 to 8 years: 1 mg up to 4 times a day for 3 days;
• from 9 to 12 years: 2 mg up to 4 times a day for 5 days.

Mode of application

Imodium capsules are taken orally half an hour before meals. Lozenges are placed on the tip of the tongue. Within a few seconds, the tablet dissolves and can be swallowed without drinking water. The drug is stopped when a formed stool appears or if there is no urge to defecate for more than 12 hours.

Use during pregnancy and lactation

Imodium during pregnancy is contraindicated in the first trimester, when only the developing tissues and organs of the fetus are most susceptible to all influences, including drugs. If it is necessary to take it in the II and III trimesters, the appointment is decided on an individual basis with the attending physician in order to adequately assess the benefits for the mother and the possible risk for the baby. A small amount of the active substance is found in breast milk, so the drug is not recommended for breastfeeding.

Indications for use

Imodium is indicated for the symptomatic treatment of diarrhea, ie. the drug does not affect the cause of the pathology that has arisen, but only counteracts the unpleasant symptom of the disease:

• allergic diarrhea;
• stool disorder on emotional grounds;
• loose stools as a side effect of other medications;
• radiation diarrhea;
• when changing the diet and composition of the diet;
• in violation of absorption processes in the small intestine;
• with infectious diarrhea - only as an aid;
• in patients with an ileostomy, to regulate stool frequency.

Contraindications

There is a list of conditions under which Imodium should not be used:

• intestinal obstruction;
• constipation;
• flatulence;
• acute ulcerative colitis;
• pseudomembranous colitis as a result of taking certain antibiotics (lincomycin, clindamycin, less often - penicillins and cephalosporins);
• age under 4 years, and in capsules - under 6 years;
• pregnancy for less than 13 weeks.

Loperamide or Imodium - which is better?

In the drug under the trade name Imodium, the active ingredient is loperamide. Imodium is an original drug, that is, it is produced by the same pharmaceutical company that developed and researched it. In addition, generics are on the market - medicines with the same composition and instructions for use, but they are produced by other manufacturers:

• Loperamide (Russia, Ukraine, Latvia);
• Vero-Loperamide (Russia);
• Diara (Russia);
• Lopedium (Slovenia, Germany, Switzerland);
• Superilop (India).

They are significantly cheaper than their prototype, since the company does not need to recoup the costs of the invention and clinical trials of the chemical formula. Nevertheless, any practitioner recommends the original drug with confidence, as it is more effective than analogues and rarely causes side effects. This is due to the form of release and the quality of the excipients that are inevitably included in the composition of the tablet or capsule.

What is Imodium Plus?

Imodium Plus is a multi-component drug, which contains two active ingredients - loperamide and simethicone. Simethicone is an antifoaming agent used to relieve the increased gas and bloating that often occurs with loperamide. Imodium Plus has similar indications and contraindications for use, but is only allowed for patients over 12 years of age.

Features of taking the medicine

If diarrhea occurs, it is advisable to consult a specialist so as not to aggravate the condition. If within 2 days of self-treatment the symptoms did not stop, be sure to consult a doctor to establish the cause of the disease and get the necessary recommendations for treatment.

With diarrhea of ​​any origin, the body loses water and salts, so they need to be replenished by taking a sufficient amount of liquid - preferably saline solutions (such as Oralit, Regidron). This is especially important in case of poisoning, when drinking plenty of water is designed not only to cover the costs of the body, but also to dissolve and remove toxins from the bloodstream. You can independently prepare a solution similar to physiological (0.9% sodium chloride), for which a teaspoon of coarse table salt (it does not contain an anti-caking agent) is dissolved in 1 liter of boiled or bottled water with a temperature of 37 - 40 ° C.

Remember that with an intestinal infection in a child, his condition can worsen dramatically. Children become dehydrated faster, tolerate intoxication more difficultly, and shock can develop - a life-threatening drop in blood pressure. They are more likely to vomit, making it difficult for them to drink enough fluids. In this case, the baby needs intravenous saline solutions and drugs. If you experience diarrhea and vomiting in a child, be sure to consult a pediatrician. If the doctor considers hospitalization necessary, do not refuse - delay can cost the baby his life.

Be careful when performing activities that require increased attention and reaction, including when driving a car. Loperamide can cause drowsiness, incoordination, stupor, depression of consciousness. If these symptoms appear, stop taking the drug and seek medical help.

Any disease is more effectively treated with an integrated approach - it is not enough just to take a remedy for diarrhea. If we are talking about an intestinal infection (salmonellosis or dysentery), an antibacterial drug comes first, with an allergic one, the search and exclusion from the menu of an intolerant product. The doctor will draw up a detailed treatment regimen and explain how to take this or that remedy.

Learn how to take imodium for diarrhea

Intestinal disorders can occur suddenly, spoiling all plans for the day. Especially when it comes to irritable bowel syndrome, which occurs due to stress and nervous strain.

Therefore, diarrhea tablets should always be on hand, capable of neutralizing the manifestations of diarrhea as soon as possible. One such drug is Imodium. It slows down intestinal motility, reducing the urge to defecate. How to use Imodium diarrhea tablets and what you need to know about it, we will analyze further.

Pharmacokinetics

The main active ingredient of the drug is loperamide, which, after entering the gastrointestinal tract, is fully absorbed, penetrating into the intestine. This substance is not able to be absorbed into the blood, therefore it acts locally, bypassing the general bloodstream. This is one of its main advantages, due to which the therapeutic effect occurs as quickly as possible.

Drug molecules act on opioid receptors, inhibiting the synthesis of prostaglandins and acetylcholines.

This, in turn, reduces the sensitivity of the mucous membrane to the irritant, which helps to reduce the manifestations of diarrhea. Slow peristalsis provokes a decrease in the rate of mass movement through the intestines, due to which the urge to defecate disappears immediately after taking the pill.

Loperamide has a selective effect, that is, it affects only the intestinal mucosa, without reducing the concentration of attention and the speed of psychomotor reactions. Also, its effectiveness can be described by the following therapeutic manifestations:

• regulates the production of mucus by the cells of the intestinal mucosa;
• an increase in the tone of the rectum and sphincter, which dulls diarrhea, reducing the urge;
• normalization of the absorption of nutrients in the intestines, which avoids dehydration and violations of the water-salt balance;
• reducing spasm of smooth muscles, which helps to eliminate unpleasant pain in the abdomen;
• slowing down intestinal motility.

The period of complete elimination is hours.

Does it help with diarrhea?

The drug reduces intestinal motility, helping to reduce the urge to defecate.

Release form and composition

The drug is produced in the form of tablets for resorption, as well as in the form of capsules coated with a gelatin shell.

Each tablet and capsule contains 2 mg of the main component of loperamide hydrochloride, as well as auxiliary components, such as natural flavor (mint), gelatin, aspartate. Tablets are packed in plastic blisters of 10 or 20 pcs.

Capsules are packaged in plastic blisters of 10 pieces. In one package 1 or 2 blisters.

Dosage and scheme of application

Tablets are intended for resorption in the oral cavity. To do this, it is placed under the tongue or on the cheek, where it slowly dissolves. In the presence of acute diarrhea, use 1 tablet every 3-4 hours. As a maintenance therapy, the drug can be used twice a day, in the morning and in the evening. In the event that on the second day the diarrhea has not decreased, a decision is made to cancel this medication and replace it with another one.

The capsules are taken orally with a small amount of water. In acute diarrhea, it is recommended to take 1 capsule three times a day. In the event that there is no bowel movement for more than three days, the medicine should be canceled.

In the presence of chronic diarrhea caused by systemic diseases, Imodium should be taken 1 tablet per day or 1 capsule. For the chronic form of diarrhea, it is recommended to use capsules, since they dissolve directly in the intestine, which provides a prolonged antidiarrheal effect. Dosage should be adjusted as the patient's condition improves. Imodium is suitable for both long-term use and single use.

The maximum daily dose is mg, which is equal to 8 tablets. Their reception is divided into equal periods of time, which ensures the maximum effect.

Indications for use

Imodium is prescribed in the presence of diarrhea of ​​various etiologies. With bacterial diarrhea, it acts as an adjuvant in complex therapy. If diarrhea is a consequence of systemic diseases and a violation of the intestinal microflora, it can be used as the main remedy for diarrhea.

In the presence of an intestinal disorder, which is caused by pathogenic microflora, treatment is supplemented with drugs such as:

1. Antibiotics (Nifuroxazide, Ceftriaxone, Cefazolin) - contribute to the destruction of bacteria not only in the intestines, but throughout the body.
2. Enterosorbents (Sorbeks, Laktofiltrum, Polysorb) - help reduce the concentration of toxic substances produced by bacteria by gluing and neutralizing them.
3. Probiotics (Linex, Bifiform, Acipol) - compensate for the deficiency of benign bacteria in the intestine, by seeding the mucous membrane.

In the event that diarrhea has other causes (stress, the presence of diseases of the stomach and intestines), the following can be introduced into the course of treatment:

• enzymes;
• diuretic and choleretic drugs;
• drugs that normalize pH;
• antidepressants.

Contraindications

Given the fact that the drug has a local effect and practically does not enter the general circulation, there are still some contraindications for use that should be considered when choosing remedies for diarrhea. These include:

• the presence of ulcerative colitis, accompanied by profuse and prolonged diarrhea;
• severe constipation (no stool for more than 4 days);
• bloating and increased gas formation;
• intestinal pathologies, in which it is extremely dangerous to reduce its motility;
• in the presence of impurities of blood and pus in the feces;
• acute dysentery, which is characterized by the addition of vomiting and high fever;
• intestinal obstruction not associated with diarrhea;
• diverticulosis;
• first trimester of pregnancy;
• children under 5 years of age, due to the presence of a high dosage of loperamide.

Nuances of application for special categories of patients

To date, it is not known for certain how Imodium affects the intrauterine development of the fetus. There are no facts that would confirm its detrimental effect on the development of the child. However, do not self-medicate during pregnancy. It is strictly forbidden to use the drug in the first trimester of pregnancy, when all the vital organs and systems of the child are laid. In the event that the doctor assesses the current situation and notes that the expected benefit to the mother is several times greater than the possible harm to the fetus, the drug is prescribed using the minimum dosage. Treatment should begin with lozenges, using no more than half at a time.

Long-term use of this medication during lactation can provoke the development of persistent constipation in a child, as well as a violation of intestinal motility. Accordingly, Imodium is not used during lactation.

Children under 5 years of age are strictly prohibited from using this medicine. After 5 years, diarrhea therapy is carried out taking into account the individual characteristics of the child, paying attention to weight. The calculation is carried out in this way: for every 20 kg of weight, 1 tablet. The frequency of receptions is 1-2 times a day. For children, it is recommended to use lozenges, as they are easier to dose. After resorption, it is not necessary to give a drink, at least a minute. The course of treatment is 1-2 days. In the absence of effectiveness, the drug is replaced by an analogue.

In elderly patients, intestinal motility slows down naturally, which occurs due to a decrease in secretion. This fact should be taken into account, since there are cases when, after taking Imodium tablets, patients complained of persistent constipation and difficulty in normalizing stools.

special instructions

It has been proven that the drug has little effect on the liver and kidneys. However, for patients who have pathologies in the functioning of these organs, it is important that monitoring is constantly carried out.

Imodium

The description is current as of 24.01.2015

• Latin name: Imodium
• ATX code: A07DA03
• Active ingredient: Loperamide (Loperamide)
• Manufacturer: Janssen-Cilag (France), Johnson & Johnson (Russia), Gedeon Richter (Hungary)

Compound

The composition of the drug includes as an active substance - loperamide hydrochloride. Additional components of capsules: lactose, talc, corn starch, magnesium stearate. The capsule shell includes yellow iron oxide, titanium dioxide, erythrosin, black iron oxide, indigo carmine, gelatin.

Release form

The medicine is available in capsules and lozenges.

pharmachologic effect

Pharmacodynamics and pharmacokinetics

The medicine acts as an antidiarrheal agent. Its active substance is a synthetic selective opioid receptor inhibitor. It affects the cells of the intestinal wall. The release of acetylcholine and prostaglandins in the gastrointestinal tract is blocked by affecting the functions of cholinergic and adrenergic neurons.

After taking Imodium, there is an increase in the tone of the anal sphincter and rectum. Feces are better retained, the urge to defecate becomes less frequent. Decreased intestinal peristalsis. The contents pass through the digestive tract longer.

The drug normalizes the amount of mucus in the intestinal lumen by reducing its secretion. It also improves the absorption of fluids and electrolytes from the gastrointestinal tract, reduces the likelihood of dehydration and electrolyte balance problems that often occur with diarrhea. The active substance reduces pain, which can be triggered by spasm of the smooth muscles of the intestinal wall.

The drug is easily absorbed from the gastrointestinal tract. Acts quickly. It is cleaved in the liver, excreted mainly with bile and feces. The half-life is 9-14 hours. The systemic impact is negligible.

Indications for the use of Imodium

Indications for the use of Imodium: the need for symptomatic treatment of acute and chronic diarrhea. Recommended for traveler's diarrhea. In this case, the drug is used for two days. But whatever the indications for the use of Imodium, the use of this remedy should be discontinued when bloody discharge appears in the feces, until their cause is clarified.

Contraindications

Do not use this drug in case of hypersensitivity to its components. In addition, the following contraindications are known:

Precautions prescribed for violations of liver function. Before using the drug, contraindications must be excluded.

Side effects

Adverse reactions may depend on the nature of the disease:

In addition, the following side effects are known:

The medicine can cause drowsiness, therefore it is undesirable when using it to perform work that is associated with the use of dangerous mechanisms.

During clinical trials, the most commonly reported adverse reactions that are characteristic of diarrheal syndrome are abdominal pain, nausea, dry mouth, drowsiness, constipation, discomfort and excessive fatigue, vomiting, dizziness, flatulence. Thus, it is difficult to distinguish these manifestations from side effects.

Application instruction of Imodium (Way and dosage)

The drug should be used only after consulting a doctor. How to use Imodium, what it will help in each case and how long it should be used, only a specialist knows. In the case of acute and chronic diarrhea, 2 capsules are usually used at the beginning of the course. Instructions for the use of Imodium for children from 6 years old informs that in this case they are usually given one capsule per day.

For maintenance therapy, the dosage is selected so that defecation is 1-2 times a day. As a rule, it is from 1 to 6 capsules for adults. The maximum dosage is not more than 8 capsules. Children from 6 years old are given no more than 3 capsules.

For those who take Imodium tablets, the instructions for use say that they should be placed on the tongue and wait until they dissolve for a few seconds, after which they should be swallowed without drinking liquid.

In case of acute diarrhea, the initial dosage is 2 tablets for adults and 1 tablet for children from 6 years of age. With the successful action of the drug, it is continued to take one tablet after each bowel movement in case of loose stools.

The initial daily dose for chronic diarrhea is 2 tablets for adults and 1 tablet for children. Then the dosage is adjusted individually so that the frequency of stools is 1-2 times a day. Every day an adult patient can lure from 1 to 6 tablets. The maximum dose should not exceed 8 tablets. For children, dosages are calculated based on weight (3 tablets per 20 kg, but not more than 8 tablets).

If, in acute diarrhea, the effect of the drug is absent for two days after use, it should be urgently stopped and another medicine should be selected. When the patient begins to have a normal stool or it is absent for 12 hours or more, the drug is also canceled.

Overdose

In case of an overdose, symptoms of CNS depression may appear: stupor, drowsiness, incoordination, miosis, muscle hypertonicity, etc. In addition, urinary retention and a complex of symptoms resembling intestinal obstruction are possible.

Children when taking the drug are more sensitive to effects on the central nervous system.

Naloxone can be used as an antidote. You may need to reapply it, as the duration of action of Imodium is longer. To identify possible symptoms of an overdose, the patient should be observed for two days. Treatment is symptomatic. Perhaps gastric lavage and the use of activated charcoal.

Interaction

The combination with P-glycoprotein blockers can lead to an increase in plasma levels of loperamide by at least 2-3 times.

Terms of sale

Released without a prescription.

Storage conditions

The medicine should be stored in a dry place at room temperature.

Shelf life

5 years. This tool can not be used after the expiration date, which is indicated on the original packaging.

Analogues of Imodium

In the pharmacy network you can find the following analogues of Imodium:

All medicines have their own characteristics of use. Imodium analogues are not recommended for use without consulting a doctor. If the drug is ineffective, you need to contact a specialist before buying another replacement product.

The price of analogs, as a rule, is noticeably lower than the cost of Imodium.

Imodium for children

From what pills will help in each case and how to take them to children under 6 years old, only a specialist knows, so they should be given under strict medical supervision.

Imodium for children from 6 years of age should be given at lower dosages than adults. They are determined by a specialist on an individual basis.

Imodium for children under 6 years of age in the form of capsules is undesirable.

Imodium during pregnancy and lactation

With caution, Imodium is prescribed during pregnancy. It does not have a teratogenic, embryotoxic and mutagenic effect on the fetus. During pregnancy, it may be prescribed if the intended benefit to the mother outweighs the possible risk to the child.

Cannot be used while breastfeeding. If admission is necessary, consideration should be given to stopping breastfeeding.

Imodium is a popular remedy for diarrhea, many people know about its action, but not everyone has read about contraindications.

The active substance of the drug is loperamide, which was obtained in Belgium in 1973. In the same year, in the United States of America, it was patented, and received the name Imodium. In 2013, Imodium was produced in the form of resorption pills, and in this form it is so far the only drug containing loperamide. In the same year, this medical product was included in the list of necessary medicines.

Imodium fights diarrhea

The active substance, in a short time, fights against the signs of diarrhea. In a normal state, the intestines absorb almost one hundred percent of water, but this property disappears during diarrhea. Therefore, with it, loose stools appear, containing a lot of water, and the work of the intestine is accelerated.

Affects the main symptoms of diarrhea, which include:

1. Restores the absorption of water by the intestines.
2. Normalizes the functioning of the intestinal muscles.
3. Reduces the ingress of fluid into the intestinal lumen.

Appearance and structure

The drug is produced in the form of pills, they are sold in blisters of ten pieces in a box and capsules in a blister of six pieces, a description of the application is attached.

The main active ingredient is loperamide hydrochloride. Additional - mannitol, gelatin, flavors, sodium bicarbonate.

Loperamide, which is in the structure of the drug, begins to function an hour after taking. The greatest result is obtained after four or five hours. Imodium can be taken by adults and children from 6 years of age. It is used to treat persistent diarrhea and "traveler's diarrhea".

Pharmacological properties of Imodium

Diarrhea stops 15-20 minutes after taking the drug

Imodium is a drug with a pronounced antidiarrheal effect. After taking the medication, the therapeutic result is formed in the interval between fifteen, twenty minutes and lasts about six hours.

From the influence of loperamide, the activity of the smooth muscles of the intestinal tract decreases, the release of acetylcholine and prostaglandin increases, because of this, the duration of the movement of excrement through the intestine increases. In addition, under the influence of a functioning element, the activity of the muscles of the anal sphincter increases.

A significant proportion of loperamide is absorbed in the intestine, however, due to intensive metabolism, systemic bioavailability is approximately 0.3 percent. Data from studies suggest that loperamide is considered a substrate of p-glycoprotein. Compounds with blood plasma proteins make up about 95 percent.

The active element of the drug is easily excreted from the intestines, completely absorbed by the liver and excreted in the bile. On average, the elimination interval is from nine to fifteen hours. Studies in children have not been conducted. It is believed that the properties of loperamide and its interaction with other drugs will be the same as in adults.

The scheme of taking pills

Initially - two for an adult and one for a child. Subsequently, one after each bowel movement. With prolonged diarrhea, first two tablets per day for an adult, one for children.

This dose is then personalized so that the stool is once or twice a day, this can be achieved with a maintenance dose of up to six tablets per day.

In a child with diarrhea, the dose is calculated based on body weight. Up to eight tablets per day. If a normal stool appears, or it is absent for 12 hours or more, the drug is canceled.

If after 12 hours the diarrhea has not passed, then it is urgent to contact a medical institution.

Benefits of Imodium

The medicine for the treatment of diarrhea has the same therapeutic medical effect as regular diarrhea pills, but at the same time it has a number of properties:

1. Dissolve under the influence of saliva.
2. Does not require drinking.
3. Does not cause problems with swallowing.
4. Convenient to use.

Contraindications to the use of Imodium

1. Intestinal infections.
2. Intestinal obstruction or suspicion of it.
3. Ulcerative inflammation.
4. due to taking antibiotics.
5. Age up to six years.
6. Intolerance to ingredients.
7. Breastfeeding time.
8. Early pregnancy.

With caution, this medicine should be used in patients with malfunctioning of the liver.

Side effect

This remedy is more or less normally tolerated by patients, but in isolated cases side effects are possible.

1. On the part of the digestive system - increased gas formation, pain in the abdominal region, intestinal cramps, vomiting, dry mouth.
2. From the side of the central nervous system - fatigue, weakness, drowsiness.
3. Allergy.

In isolated cases, it is difficult to determine the relationship between taking loperamide and the existence of the above symptoms. In addition, because medical research is conducted under different conditions, the frequency of unwanted interactions in clinical trials of one drug cannot be compared with the frequency of adverse reactions of another substance and may not reflect the frequency of adverse reactions in medical practice.

Use in pregnancy

In the early stages of pregnancy, the drug is not recommended, since at this moment all the organs of the fetus are laid, and the drug effect can disrupt the process. Then the use of the drug is possible only if the expected benefit is greater than the risk to the baby.

The active substance is able to penetrate into milk, so the drug is not used during breastfeeding.

Overdose

When taking increased doses of the substance, an overdose may occur, which is manifested by the following symptoms:

1. The depressed state of the central nervous system is characterized by clouding of consciousness, movement disorders, lethargy, apathy, weakness.
2. Respiratory dysfunction.
3. Development of intestinal obstruction.

In children, signs of an overdose are most often observed. Treatment includes emergency gastric lavage, the patient is given activated charcoal or other enterosorbents. If necessary, treatment is carried out, with difficulty in breathing, artificial ventilation of the lungs is carried out. Naloxone is a kind of antidote, but it can help if no more than three hours have passed after taking Imodium. The patient must be under medical supervision.

No data were found on the relationship of Imodium with other medicines.

special instructions

If you experience discomfort in the abdomen, you need to stop using the medicine. During diarrhea, dehydration of the body occurs, it is necessary to direct the treatment to fluid replacement.

If blood is present in the stool, the drug should be discontinued.

In patients with immunodeficiency, treatment should be carried out under strict control, if signs of swelling are observed, the drug is canceled. To maintain the body of the patient during the treatment period, it is necessary to drink plenty of water, take special food.

Are Imodium pills safe?

The main problem with Imodium is that it contains opiates (opium drugs). In America, it is in demand among drug addicts who use heroin. If you take more pills than necessary, then the condition will be the same as after taking drugs. In America, deaths have even been recorded after using the drug.

Abuse of over-the-counter antidiarrheals can lead to heart rhythm disturbances and eventually death.

Struggling with the signs of diarrhea, a person prevents the body from being cleansed of germs and bacteria. Frequent use of the drug leads to the fact that the disease lasts longer.

Analogues

Imodium analogue

Analogues include:

• Vero-loperamide;
• Diara;
• Diarol;
• Lopedium;
• Lopedium ISO;
• Enterobene.

They have a composition similar to Imodium and are available in different dosage forms, in the form of tablets, capsules, syrups. Some of them in a syrupy state are allowed to be taken by children from 2 years old, for example, Enterobene.

Analogues are also sold without a prescription. But they also have side effects. At the same time, the cost of analogues is much lower than the original.

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In the drug Imodium, the indications for use are rather limited - the drug is used only in the treatment of diarrhea of ​​​​a certain etiology. You can not use capsules and lozenges on the advice of a neighbor or a pharmacist in a pharmacy - such treatment may result in urgent hospitalization. Reception of Imodium is possible only after establishing the cause of indigestion and in the dosages recommended by the gastroenterologist.

Imodium is used in the treatment of diarrhea of ​​various etiologies.

Characteristics

The causes of disruption of the gastrointestinal tract are varied. Imodium is a pharmacological drug designed to quickly eliminate diarrhea, which is not always beneficial for a person. It would seem that loose stools, painful abdominal cramps and profuse sweating significantly complicate life, so you need to get rid of them urgently. In some cases, diarrhea is a defensive reaction of the body, with the help of which it tries to remove pathogenic pathogens of intestinal infections.

The therapeutic effect of Imodium is due to the main active ingredient of tablets and capsules. As a result of blocking the receptors of the mucous membranes of the small and large intestines, the tone of its smooth muscle muscles decreases. This leads to:

• tight closure of the sphincter;
• slowing down the movement of feces.

Imodium did an excellent job - it slowed down intestinal motility and eliminated the pain syndrome. But harmful viruses and bacteria have not gone away and now they can freely multiply and poison the body with the products of their vital activity. Therefore, gastroenterologists strongly recommend not taking Imodium for diarrhea that lasts no more than 2-3 days. In this case, adsorbents or enterosorbents will help solve the problem. Imodium is indicated for use only with prolonged diarrhea, which can provoke a serious and dangerous condition for the human body - dehydration.

pharmachologic effect

Propulsive peristalsis begins to decline rapidly after taking Imodium in a single dose. It does this by blocking opiate-sensitive receptors in the intestinal wall. The movement of the food bolus inside the gastrointestinal tract slows down, and the mucous membranes begin to intensively absorb excess fluid, preventing dehydration. Increased tone of the anal sphincter:

• promotes the retention of feces;
• reduces the frequency of urge to empty the bowels.

An environment favorable for the development of diarrhea is the excessive production of thick mucus in the organs of the digestive system. The main action of Imodium is aimed at normalizing its production, reducing the severity of painful abdominal cramps that occur during contractions of the smooth muscle of the intestine. Penetrating into the gastrointestinal tract, the drug is rapidly absorbed by the mucous membranes of the small and large intestines.

The duration of the therapeutic effect of the drug is about 6 hours. The metabolism of Imodium takes place in hepatocytes - liver cells, after which the metabolites of the drug are excreted during bowel movements. Only a small part of the active substance in the form of conjugates leaves the body with urine.

Release form and composition

Imodium is produced in two dosage forms - lozenges and enteric capsules at a dosage of 0.002 g. Each package contains:

• 6 or 20 capsules;
• 6 or 10 tablets.

In addition to the main active ingredient of loperamide, the composition of the dosage form includes auxiliary components necessary for the formation of tablets and capsules. Iron oxide, titanium dioxide, and sodium erythrosin are used for coloring, and gelatin is needed to form a strong capsule. The gelatin shell prevents the absorption of Imodium in the stomach, so the absorption of the active substance occurs directly in the intestinal cavity.

The composition of the tablets includes sucrose and mint flavor. This contributes to the rapid dissolution of the drug and accelerate the therapeutic effect. Only a gastroenterologist chooses the dosage form of Imodium for the patient, guided by the severity of the underlying disease and the presence of pathologies in history.

Imodium begins to act immediately after taking, helping to get rid of diarrhea

Indications for use

Imodium is not used as an etiological drug, its scope is the elimination of diarrhea as a symptom of any disease. It does not inhibit the growth of pathogenic microflora, so its use in the treatment of intestinal infections is not always advisable. The indication for taking Imodium is the symptomatic treatment of acute and chronic diarrhea:

• caused by the penetration into the body of an allergic agent (pollen, animal hair, vapors of household chemicals);
• provoked by emotional shock or depression;
• developed after radiation therapy.

Course treatment with antibacterial drugs often causes digestive upset - constipation or diarrhea. If patients have loose stools for 2-3 days with each bowel movement, then gastroenterologists recommend taking Imodium in the form of lozenges. Capsulated drug is usually taken with them on the road by tourists and travelers. They may develop what is known as functional diarrhea due to changes in diet and water composition.

The drug is used for the correct discharge of feces in patients after surgical interventions. Usually, such a need arises when the loop of the ileum is brought out onto the wall of the peritoneum and a fistula is formed. With the help of Imodium, intestinal peristalsis is corrected, the frequency and amount of stool decreases, and its consistency becomes denser.

Dosage and administration

Imodium capsules and tablets are intended for internal use. Capsules are taken without chewing, and washed down with a large amount of pure non-carbonated water. Tablets are simply placed on the tongue, and they gradually dissolve in the oral cavity.

single doses

How to take imodium for diarrhea:

• single dose for adults - 2 capsules or tablets;
• single dose for children over 6 years old - 1 capsule;
• a single dose for children over 4 years old - 1 tablet.

After each act of defecation, you should take a tablet or capsule. If after 2 days from the start of the reception there is no improvement, then the drug must be canceled and seek help from a gastroenterologist. He will adjust the dosage or replace the drug.

Imodium tablets have a pleasant mint flavor and dissolve quickly in the mouth.

Daily doses

The maximum daily dose is:

• for adults - 16 mg;
• for children over 6 years old - 6 mg.

Advice: "After reducing the severity of symptoms or the absence of a bowel movement for 12 hours, stop taking Imodium."

The duration of the course of treatment and the daily dose are determined only by the doctor. The number of capsules and tablets for a single dose is selected individually, depending on the complexity and nature of the diagnosed pathology. Imodium is not used or is used with caution in the treatment of infectious diarrhea, which occurs against the background of dehydration of the body and the loss of a significant amount of mineral compounds.

Contraindications

Imodium is not used to treat patients with individual sensitivity to its active substance or auxiliary ingredients. The pharmacological drug is also contraindicated in patients with the following pathologies:

• lack of enzymes responsible for the breakdown of lactose;
• lactose intolerance;
• intestinal obstruction;
• the presence of diverticula in the intestinal wall;
• acute stage of ulcerative colitis;
• the first three months of childbearing.

Warning: “Chronic constipation cannot be treated with Imodium without diagnostics and medical recommendations. This will only aggravate the condition, and in the presence of intestinal obstruction, the risk of violation of its integrity will increase.

The drug in the form of lozenges can be used in the treatment of children older than 4 years, in the form of capsules - older than 6 years. Imodium is not used during lactation because of its ability to penetrate into breast milk.

Side effects

Undesirable side effects are rare and are usually caused by self-medication or neglect of medical recommendations. Imodium should be discontinued if the following signs of intoxication are observed:

• redness and rashes appeared on the skin, similar to the clinical picture of urticaria or atopic dermatitis;
• pain appeared in the epigastric region and in the lower abdomen;
• the work of the gastrointestinal tract is disrupted: a person is worried about nausea, bouts of vomiting, increased gas formation;
• growing signs of dehydration and water-electrolyte imbalance;
• urination occurs irregularly, the volume of urine has decreased.

The drug is not suitable for the patient if, after its use, lethargy, lethargy, apathy and drowsiness occur.