Dicloberl - instructions, application, reviews. Indications for the use of various forms of the drug dicloberl Candles dicloberl analogues

Dicloberl is a non-steroidal drug that has an anti-inflammatory, decongestant.

The composition of the drug includes diclofenac sodium. By inhibiting the synthesis of prostaglandins, it has a pronounced anti-inflammatory property. It is also an antipyretic, analgesic.

It has an anti-edematous effect. Reduces the angesive property of platelets when exposed to collagen, ADP.

When administered intramuscularly, Cmax in plasma reaches within 20 minutes.

When taken orally, diclofenac is completely absorbed from the intestines and Cmax in the blood reaches within an hour or two.

When taking a suppository, Cmax in the blood reaches within thirty minutes.

Application

• Rheumatism;
• Rheumatism;
• Pain in injuries;
• Crick;
• joint disease;
• Osteoarthritis;
• Rheumatoid arthritis;
• Alkylosing spondylitis;
• primary dysmenorrhea.

Instructions for use

The drug Dicloberl 75 is injected intramuscularly deep into the muscle. One ampoule is enough per day (one ampoule - 75 mg.). With severe pain, it is possible to introduce 2 ampoules (150 mg) per day, no more. This drug for intramuscular injection should be taken as needed, for quick pain relief, it is recommended to administer the drug once at the beginning of treatment, then if it is necessary to take Diclobird for a long time, then it is prescribed in oral or rectal form.

Dicloberl 50 in the form of tablets is taken after meals, one, two or three tablets per day, divided into two or three doses. The course of therapy and dosage is prescribed only by the doctor to each patient individually, based on the nature of the disease.

Dicloberl - retard in the form of capsules take 1 capsule per day 100 mg.

Dicloberl 50 in the form of a suppository should be taken after a bowel movement, injected into the rectum, depending on the disease, two or three times a day. The dose per day is not more than 150 mg. For each patient, the doctor individually selects the dosage and course of therapy, depending on the severity of the disease.

Side effects

• gastrointestinal tract: constipation, possible GI bleeding, nausea, loss of appetite, exacerbation of gastrointestinal diseases, diarrhea, dyspepsia, abdominal pain, pancreatitis, liver damage.
• CNS: insomnia, dizziness, confusion, headache, fear, irritability, fatigue, convulsions, nightmares, impaired taste perception.
• From the side of the SSS: leukopenia, thrombocytopenia, chest pain, agranulocytosis, blood pressure disorder, palpitations.
• allergic reactions: rash, abscess at the injection site, itching, swelling of the face, burning at the injection site, swelling of the larynx, tongue, bronchospasm, Layell's syndrome, anaphylactic shock.

Contraindications

Dicloberl should not be taken if:

1. peptic ulcer of the gastrointestinal tract;
2. bronchospasm;
3. peptic ulcer;
4. an allergic reaction to the components of the drug;
5. violation of hematopoiesis;
6. children under 15 years old.

Do not prescribe the drug in the form of injections to patients with signs of bronchial asthma, after surgery. Also, do not prescribe a drug for i / m administration to patients with chronic bowel disease, with a disease of the upper respiratory tract.

When treating with Dicloberl 75, alcohol intake is prohibited.

If you have signs of general malaise when you first take the drug, tell your doctor and you should not use this drug again.

Long-term use of several painkillers at once can damage the kidneys.

The drug is also prohibited during lactation and pregnancy.

According to the results of clinical trials, it was revealed that when taking the drug in high doses and for a long time, there is a risk of heart attack, stroke.

If hematopoiesis is impaired, the following symptoms may appear: nosebleeds, sore throat, weakness, fever.

Interaction

Joint reception with Digostin, lithium preparations, their blood levels may increase. When used together with potassium-sparing diuretics, an increase in blood concentrations of potassium is possible.

When taken with diuretics and with drugs that reduce hypertension, the effect of the latter may decrease.

Reception with other nonsteroidal drugs and glucocorsteroids may increase undesirable effects on the gastrointestinal tract.

Taking the drug a day before or after methotrexate may increase its toxicity and increase its concentration.

Joint reception with antiplatelet agents, it is necessary to conduct constant monitoring of the blood system.

The use of cyclosporine significantly increases its toxic effect.

There is evidence that a change in blood glucose levels is possible in patients who suffer from diabetes mellitus and who have had a change in the dosage of insulin and antidiabetic agents.

Dicloberl is a non-steroidal anti-inflammatory drug with anti-inflammatory and analgesic effects. The active substance is diclofenac.

Diclofenac belongs to the NSAID group of phenylacetic acid derivatives. It has a pronounced anti-inflammatory, analgesic and antipyretic effect, reduces tissue swelling during inflammation. These effects are associated with the ability to block the synthesis of prostaglandins (inflammatory mediators). Inhibits platelet aggregation caused by ADP and collagen.

The use of Dicloberl for the treatment of rheumatic diseases contributes to a significant reduction in the severity of pain at rest and during movement, morning stiffness of the joints, and their swelling.

In the treatment of inflammation caused by trauma or surgery, the anti-inflammatory and analgesic effect of Dicloberl is manifested by the rapid elimination of pain, a decrease in inflammation and swelling of damaged tissues. Also, the drug reduces the need for opioids to eliminate postoperative pain.

Indications for use

What helps Dicloberl? According to the instructions, the drug is prescribed in the following cases:

• rheumatic diseases of inflammatory and degenerative origin, including rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease), acute attacks of gout, osteoarthritis, spondyloarthritis;
• rheumatic diseases of extra-articular soft tissues, including humeroscapular periarthritis, tendinitis, tendovaginitis, bursitis;
• pain syndromes from the spine;
• inflammation after injuries, including sprains, dislocations, fractures.

Dicloberl tablets, capsules and suppositories are used to relieve pain of post-traumatic and postoperative genesis, which is accompanied by inflammation and edema, including conditions after orthopedic and dental surgeries.

Additional indications for Dicloberl tablets and suppositories:

• primary dysmenorrhea, adnexitis and other gynecological pathologies accompanied by inflammation and pain syndrome;
• severe form of pharyngotonsillitis, otitis and other inflammatory diseases in otorhinolaryngology, accompanied by severe pain syndrome (as an adjunct in complex therapy).

Instructions for use Dicloberl, dosage

Dicloberl injections are administered intramuscularly. The average daily dosage, according to the instructions for use - 1 ampoule Dicloberl 75 mg.

The maximum allowable daily dose should not exceed 150 mg (2 ampoules).

Candles

Candles Dicloberl are injected deep into the rectum (only after the act of defecation). The dosage is determined individually by the attending physician, depending on the severity of the disease.

The daily dose is from 50 to 150 mg \ 2-3 times a day.

• Primary dysmenorrhea - 50 to 150 mg per day. In the absence of the desired therapeutic effect, the initial daily dose can be increased to 200 mg over several menstrual cycles. The use of suppositories should be started when the first pain symptoms appear. The duration of treatment depends on the dynamics of regression of the pain syndrome.
• Migraine attacks - initial dose of 100 mg per day. To achieve a clinical effect, repeated administration of the Dicloberl 100 mg suppository is allowed on the first day of treatment. In the following days, if necessary, treatment can be continued (the daily dose should not exceed 150 mg, it is divided into 2-3 injections).
• Juvenile rheumatoid arthritis - children over the age of 14 are prescribed Dicloberl 50 suppositories at the rate of not more than 3 mg per 1 kg of the child's weight. The maximum daily dose is 150 mg.

Capsules

Capsules Dicloberl retard take 100 mg (one capsule) once a day. If necessary, other forms of the drug may be additionally prescribed.

If the symptoms of the disease are most pronounced at night and in the morning, the capsules should be taken in the evening.

Pills

Dicloberl tablets are taken orally during meals with a small amount of liquid.

According to the instructions, the daily dose is from 50 to 150 mg (1-3 tablets of Dicloberl 50 mg) - 1 tablet 2-3 times a day. The maximum dosage is 200 mg per day.

The duration of treatment is determined by the attending doctor.

special instructions

To reduce the risk of side effects of diclofenac, it is recommended to use the minimum effective dose of Dicloberl for a short period of time.

The doctor prescribes the dosage form, dose and period of treatment individually, taking into account clinical indications.

For the treatment of elderly patients, debilitated patients or patients with low body weight, it is recommended to use the lowest effective dose.

The total daily dose when using several dosage forms of Dicloberl should not exceed 150 mg of diclofenac.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Dicloberl:

• From the side of the central nervous system - headache, dizziness, fatigue, insomnia, agitation, impaired sensitivity, change in taste, impaired vision and perception of sounds, a sense of fear, disorientation, convulsions, depression, nightmares, confusion, stiff neck muscles.
• From the digestive system - glossitis, dyspepsia, esophagitis, pancreatitis, liver damage, exacerbation of diseases of the gastrointestinal tract, abdominal pain, constipation, diarrhea, nausea, vomiting, minor gastrointestinal bleeding, decreased appetite. Bloody diarrhea, hematemesis and melena can sometimes be observed.
• From the side of the cardiovascular system - palpitations, chest pain, arterial hypertension, lowering blood pressure, palpitations, pain in the chest.
• On the part of the hematopoietic system - agranulocytosis, anemia, leukopenia, thrombocytopenia.
• Allergic reactions - bullous rash, skin rash, burning sensation at Dicloberl injection sites, Lyell's syndrome, swelling of the face, larynx and tongue, Stevens-Johnson syndrome, bronchospasm, anaphylactic shock.

Candles after the introduction often cause a burning sensation in the anus.

Contraindications

Dicloberl is contraindicated in the following cases:

• acute ulcer, bleeding or perforation of the intestine / stomach;
• allergy to the components of the drug;
• increased risk of postoperative bleeding, hemostasis disorders, cerebrovascular bleeding or hematopoietic disorders;
• bleeding or perforation of the digestive organs in the past associated with the use of anti-inflammatory non-steroidal drugs;
• inflammatory bowel disease;
• exacerbation of peptic ulcer, peptic ulcer bleeding, including in the past;
• third trimester of pregnancy;
• congestive heart failure;
• cerebrovascular disorders in persons who have had a stroke or cases of ischemic attacks;
• liver or kidney failure;
• peripheral arterial disease;
• ischemic heart disease in people who have had a heart attack or suffering from angina pectoris;
• children's age up to 14 years for the appointment of suppositories at a dose of 50 mg;
• age up to 18 years.
• treatment of pain syndrome before and after coronary artery bypass grafting;
• allergic reactions to ibuprofen, aspirin or other non-steroidal anti-inflammatory drugs.

Under medical supervision, it is recommended to use Dicloberl for porphyria, systemic lupus erythematosus, mixed collagenoses, high blood pressure (BP), heart failure, impaired renal function, severe liver dysfunction, hay fever, nasal polyps or obstructive airway diseases, in patients with ulcerative colitis, Crohn's disease or peptic ulcer of the stomach and intestines (including history), in the period after major surgery.

Overdose

It is manifested mainly by disorders of the nervous system - headache, dizziness, disorientation and loss of consciousness (in addition, myoclonic convulsions may occur in children), as well as abdominal pain, nausea and vomiting, gastrointestinal bleeding, impaired liver and kidney function.

Treatment is symptomatic - there is no specific antidote.

Dicloberl analogues, price in pharmacies

If necessary, you can replace Dicloberl with an analogue of the active substance - these are drugs:

1. Diclovit,
2. Diklak,
3. Almiral,
4. bioran,
5. Argett Rapid,
6. Diklobru.

When choosing analogues, it is important to understand that the instructions for use of Dicloberl, the price and reviews of drugs of similar action do not apply. It is important to consult a doctor and not to make an independent replacement of the drug.

Price in Russian pharmacies: Dicloberl 75mg ampoules - from 290 to 479 rubles, 10 suppositories 50 mg - from 250 to 284 rubles.

Store at a temperature: tablets - up to 30 ° C, capsules, solution, suppositories - up to 25 ° C. The solution should be stored in a place protected from light, do not allow freezing. Shelf life - 3 years. Conditions for dispensing from pharmacies - by prescription.

special instructions

During long-term treatment, constant monitoring of liver function and the content of liver enzymes is prescribed. In case of violation of the work of the organ or aggravation of problems, the use of Dicloberl should be stopped immediately.

The use of diclofenac may be associated with an increased likelihood of thrombotic events (heart attack or stroke).

With long-term use of Dicloberl, regular monitoring of the blood test should be carried out.

Patients who experience vertigo, blurred vision, impaired nervous activity, drowsiness, fatigue, lethargy during treatment with the drug should not drive a car.

Interaction with other medicines

Dicloberl increases the plasma concentration of digoxin, methotrexate, lithium preparations and cyclosporine.

Reduces the effect of diuretics, against the background of potassium-sparing diuretics, taking Dicloberl increases the risk of developing hyperkalemia; against the background of anticoagulants, antiplatelet and thrombolytic drugs (alteplase, streptokinase, urokinase), the risk of bleeding (often the gastrointestinal tract) increases.

Reduces the effect of antihypertensive and hypnotic drugs.

Treatment with Dicloberl increases the likelihood of side effects of other NSAIDs and GCS (bleeding in the gastrointestinal tract), methotrexate toxicity and cyclosporine nephrotoxicity.

ASA reduces the concentration of the drug in the blood. Simultaneous use with paracetamol increases the risk of developing nephrotoxic effects of Dicloberl.

Reduces the effect of hypoglycemic drugs.

Cefamandol, cefoperazone, cefotetan, valproic acid and plicamycin increase the incidence of hypoprothrombinemia.

Cyclosporine and Au preparations increase the effect of the drug on Pg synthesis in the kidneys, which is manifested by an increase in nephrotoxicity.

Simultaneous administration with ethanol, colchicine, corticotropin and St. John's wort increases the risk of bleeding in the gastrointestinal tract.

Medications that cause photosensitivity increase the sensitizing effect of the drug to UV radiation.

Drugs that block tubular secretion increase the plasma concentration of Dicloberl, thereby increasing its effectiveness and toxicity.

For diseases of the joints and nerves, Dicloberl is widely used. The article will tell you in what cases and for what it is used, and helps to understand how to take the drug correctly with concomitant diseases in order to avoid problems with unwanted effects.

Attention is paid to important changes in the instructions for the use of Dicloberl in injections, tablets and retard capsules, prices for analogues and reviews about the drug.

Instructions for use

Dicloberl is a German medicine containing the anti-inflammatory component diclofenac. The substance belongs to the nonsteroidal group of chemical compounds and, in addition to reducing inflammation, it exhibits antipyretic and analgesic effects.

Indications for use

The drug is used as part of therapeutic schemes for rheumatic lesions of the musculoskeletal system, in neurological, traumatological, surgical and general practice to reduce pain and inflammation. Injections are used for a short time, up to 2 days, in cases:

• articular and extra-articular manifestations of rheumatism;
• spondylitis;
• osteochondrosis;
• inflammation of the vertebrae with ankylosing;
• osteoarthritis;
• rheumatoid lesions of the joints;
• arthritis with pain in gout;
• pain relief after injuries and operations;
• hepatic and urinary colic.

Tablets and capsules are intended for long-term treatment listed conditions and for the treatment of infectious and inflammatory lesions of different localization: in the pathology of the ENT organs, in gynecology, urology.

In the same cases, suppositories are used for insertion into the rectum. In diseases of the pelvic organs, they work better than tablets and capsules.

Forms of release and composition

The drug is available in several dosage forms:

• Solution for injection "Dikloberl N75". Produced in ampoules of 3 ml, the dose of diclofenac is 75 mg.
• Tablets of 50 milligrams, containing standard auxiliary ingredients.
• Capsules "Dikloberl-retard" with a delayed release of the active substance with a dosage of 0.1 grams.
• Suppositories for rectal use 50 and 100 milligrams. They contain solid fat as a formative component.

Price in pharmacies

The average cost of a drug in Ukrainian pharmacies: the price of a package of 5 ampoules is 105 hryvnia, the same price is for 50 tablets, 10 suppositories or 20 retard capsules will cost 120 hryvnia.

In Russia, Dicloberl is not registered and is not available for purchase in pharmacies, it can only be purchased in neighboring countries - Kazakhstan, Belarus, Ukraine.

Features of use

For a long time, diclofenac was considered a reference substance for the treatment of inflammation, but it began to lose to new drugs due to relatively frequent undesirable effects.

Its gastrotoxicity is well known - a negative effect on the stomach. This problem is partially solved by taking the medicine after eating and using medicines that reduce acidity - omeprazole, ranitidine.

Important and much more dangerous is the likelihood of developing thrombosis - the list of side effects includes formidable complications in the form of myocardial infarction and stroke. To reduce the risk, Dicloberl should be avoided for any problems with heart rhythm, congestive circulatory failure and thrombosis, and not only in the presence of obvious contraindications such as coronary artery disease or a previous heart attack.

It is necessary to remember about the decrease in the effect of antihypertensive drugs against the background of long-term use of diclofenac and not to exceed the duration of treatment with Dicloberl injections, which, according to the instructions, should not be more than 2 days.

The use of the minimum required doses allows you to reduce the undesirable effects of the drug. This also applies to substitute drugs.

Dicloberl's analogs

Pharmacies offer a huge selection of diclofenac preparations in all forms of release and a sufficient number of similar anti-inflammatory drugs containing other active ingredients.

Identical to suppositories, retard capsules and Dicloberl ampoules, medicines are represented by several dozen cheap generic drugs of Russian and foreign production with names according to the active substance, and the original Voltaren drug (a reference drug that costs more than others).

The cost of other synonyms is much more affordable:

• Russian-made injections cost from 30 rubles for 5 ampoules, foreign - from 55 rubles;
• imported tablets 50 milligrams No. 20 cost from 45 rubles, domestic - from 30;
• price of candles differs by 5 times, amounting to 40-60 and 250 rubles for Russian and British suppositories;
• differences in the cost of capsules also in favor of the domestic manufacturer: packages of 20 pieces are sold at 70 and 40 rubles.

At the same time, some patients note the best effect from the use of expensive diclofenac preparations.

Most other NSAIDs replace Dicloberl depending on the clinical situation. Over-the-counter anti-inflammatory drugs - ibuprofen, naproxen, and aspirin are less potent than diclofenac.

Meloxicam, aceclofenac, celecoxib and ketoprofen will have a similar effect in chronic joint damage. With severe acute pain syndrome, Dicloberl can be replaced with lornoxicam and ketorolac. Often trying to replace diclofenac with nimesulide, but this option is much worse.

Meloxicam

The best replacement option in the treatment of joints, because improves the condition of the cartilage. Produced in ampoules of 15 mg, injected intramuscularly 1 time per day.

Tablets of 7.5 and 15 milligrams are intended for a single daily intake. Medication not so harmful to the stomach and can be used for a long time.

The imported drug Meloxicam-Teva costs 210 rubles for 10 tablets of 15 mg. This analogue of the drug Dicloberl in injections is available in Russia at a price of about 450 rubles for 5 ampoules, and a Russian-made medicine will be 2-3 times cheaper.

Aertal

An improved version of diclofenac, available in the form of oral forms. Aceclofenac is chosen when looking for something to replace Dicloberl in retard capsules and tablets. The analogue is closest in action and application features.

The cost of the Hungarian drug "", 20 doses of 100 mg in tablets or packets are sold for 320-390 rubles. Russian-made aceclofenac costs three times less.

This analogue of Dicloberl can be purchased in Belarus, the cost is from 10 Belarusian rubles.

Ketoprofen

Available in ampoules, capsules, suppositories and tablets. It has a similar pharmacological profile and is easier to tolerate.

Prices for inexpensive Russian preparations of ketoprofen: 10 ampoules - 70 rubles, 10 candles - 250 rubles, tablets and capsules of 50 and 100 milligrams cost 70 and 130 rubles for 20 pieces.

Celecoxib capsules

Anti-inflammatory drug of selective action, replacing oral variants of Dicloberl, produced in doses of 100 and 200 mg. Does not affect the stomach.

Its options in Russia: foreign Dilaxa and Russian Roucoxib-Routek with a cost of 275 rubles for 10 doses. In Ukraine, an imported analogue of Dicloberl is available - Rancelex, 10 capsules cost 50 hryvnia.

Ketorolac

A medicine in ampoules and tablets used for pain relief in postoperative conditions, injuries, toothache, and even in oncology. It is not used for inflammatory diseases of the joints, since it shows the maximum effect in violation of the integrity of the tissues.

Lornoxicam

Shows the strongest analgesic effect in inflammatory and traumatic pain. Its analgesic effect is comparable to ketorolac, but it loses in price.

In Russia, only the original Austrian drug lornoxicam Ksefokam is sold, 10 bottles of this Dicloberl analogue for injections of 8 mg each cost from 600 rubles, 10 tablets of the same dosage - 180 rubles. In Ukraine, its cheap substitute Larfix is ​​available at 30 hryvnia for 10 tab.

Nimesulide (Nimesil)

This drug should be mentioned separately, because it is often positioned as a remedy for the treatment of joints and is advised as a substitute for diclofenac. In fact, osteoarthritis was excluded from the list of indications for its use, the drug is recommended to be prescribed only for acute pain and dysmenorrhea. The cost of 30 doses of 100 mg - from 650 rubles.

Replacing a non-steroidal anti-inflammatory drug, the doctor determines how much the strength of action can change when using an analog, so you should use the help of doctors. You do not need to select another medicine on your own.

Dicloberl is a non-steroidal drug, its main property is to relieve inflammation in soft tissues. Able to resist more than thirty diseases. Very well suited for treatment in complex therapy. It is extremely rarely used for self-treatment.

Various forms of release and dosage easily allow you to choose the most convenient regimen for each specific case. Injections and suppositories are most often used in gynecology. Whereas tablets and capsules are convenient for long-term treatment

Properties

Dicloberl is described as a non-steroidal anti-inflammatory drug. It is a derivative of phenylacetic acid.

Able to work as an active antipyretic agent, providing a timely anti-inflammatory effect.

Well resists inflammatory processes in soft tissues.

It is able to penetrate into various links in the development of inflammatory processes and acts on them pointwise, preventing the focus of inflammation from spreading further.

If inflammatory processes have arisen after surgery or as a result of injuries, the timely intake of Dicloberl will help not only eliminate the pain effect during movement, but also prevent the formation of surgical edema.

In case of damage to soft tissues, it reduces sensitivity, helps to minimize the susceptibility of nerve fibers in the damaged area.

Penetrating into the body, Dicloberl begins to actively work to inhibit the reproduction of prostaglandins, which are responsible for the reproduction of foreign bodies in the body. Thanks to this, it is easier for active substances to accumulate their strength in a timely manner to fight the focus of inflammation.

Dicloberl is also capable of exerting a mild analgesic effect even if the source of pain is not of a rheumatic nature.

When using dragees, the maximum possible concentration in the body occurs no earlier than an hour later, and no later than 15 hours later. It is metabolized without residue and excreted in the urine no less than 20 hours after the procedure.

After injections, the effectiveness of the drug is slightly lower than that of tablets. But at the same time, the absorption rate is faster, the maximum concentration occurs after 10-20 minutes. It easily penetrates into the joint fluid. The process of releasing active substances from the body is also more active. 12 hours is enough for the body to get rid of all the products of the drug.

With the introduction of suppositories, the maximum permissible concentration occurs within half an hour.

Penetrating into the body, about a third of the total volume is metabolized. Once in the intestine, it is eliminated and excreted in the feces. The rest is excreted by the kidneys.

Composition and form of release

The main component of Dicloberl is diclofenac sodium. To make it easier to use in treatment, Dicloberl is produced in three varieties. In the form of suppositories, solution for injections and dragees. Each sample is made in its concentration. Such a variety of forms allows you to choose the most appropriate treatment regimen for this particular case.

Dicloberl in suppositories is placed only rectally. Produced in concentrations of 100 and 50 mg. In addition to the main component, corn starch, ethyl alcohol, solid fat, propyl gallate are added to their composition.

The solution for injections is already ready for use, additional dilution is not required. Each ampoule contains 75 mg of sodium. It contains propylene glycol, injection, acetylcestein, benzyl alcohol, sodium hydroxide as binding ingredients.

Each Dicloberl tablet contains 50 mg diclofenac sodium. As related components, it contains magnesium stearate, corn starch, yellow food coloring, simethicone emulsion, talc, glucose monohydrate, titanium dioxide, methacrylic acid.

Dragee Dicloberl may include 100 mg of diclofenac sodium. This dosage has its own name, Dicloberl Retard capsules. Dicloberl Retard as related ingredients includes sucrose, maltose monohydrate, the same corn starch, gelatin, white food coloring and talc. All this allows the dragee to dissolve and be absorbed better in the body. Dicloberl Retard, unlike its lightweight companion, is able to accumulate diclofenac sodium in the body. From what the result after its reception lasts longer.

Which form of the drug to choose for treatment, only the doctor can decide.

The choice can be influenced not only by age and existing concomitant diseases, but also by the body's susceptibility to the components of the drug, as well as the duration and severity of the disease.

Indications for use

It is not for nothing that this drug has so many design options for the active substance. With a clear understanding of the diagnosis, it is easy to choose the most appropriate form in a particular situation.

Ampoules

Dicloberl injections are most often prescribed for systemic joint disease, especially when it is chronic, with osteoarthritis - the most common type of arthritis, with rheumatoid arthritis, it copes well with pain in osteochondrosis.

Injections are often prescribed for colic, both of a renal and hepatic nature, for non-articular rheumatism. It is effective against migraine attacks and pains of various etymologies, in the inflammatory process as a result of minor injuries, surgery, after orthopedic or dental procedures.

Capsules

Dicloberl in capsules is often prescribed for injuries of various kinds (sprain, fractures, dislocations), in such conditions the drug is able to cope well with both pain and prevent possible inflammation. Often, dentists recommend drinking a course of capsules after minor dental and orthopedic interventions (tooth extraction). The purpose of the appointment is to stop pain, prevent inflammation. The course of capsules is also able to minimize inflammation and relieve pain in various diseases of the musculoskeletal and nervous system of the spinal column.

Dicloberl in tablets works well with ENT pathologies accompanied by pain and inflammation, in combination with other drugs it is able to cope with especially complex forms of these diseases (acute otitis media, pharyngitis, tonsillitis). Included in complex therapy for systemic joint disease, especially when it is chronic (Bekhterev's disease).

Assign tablets and after surgical intervention of a dental nature. In gynecology, Dicloberl is often prescribed for inflammatory pathologies, especially if the disease is accompanied by pain. It treats gout well in the acute stage, accelerates the recovery process after an injury, especially if an inflammatory process occurs in the body. Often, Dicloberl is included in the complex of drugs for the restoration of spinal lesions for its ability to relieve pain well. Helps to tidy up soft tissues after rheumatic damage.

Dicloberl suppositories are often prescribed for systemic connective tissue disease (rheumatoid arthritis, including its juvenile form), for systemic joint disease, especially when it is chronic (Bekhterev's disease), and for spondyloarthritis.

Included in the complex therapy of non-articular rheumatism. It is widely used in gynecology for inflammatory pathologies, especially if the disease is accompanied by pain. Candles Dicloberl effectively work against gout, especially during an exacerbation of the disease. Well relieves pain in various diseases of the musculoskeletal and nervous system of the spinal column. Actively works to relieve inflammation and pain after injury, surgery.

A course of Dicloberl is also recommended after a small intervention of a dental and orthopedic nature. Can get rid of migraines. It works well with ENT pathologies accompanied by pain and inflammation, in combination with other drugs it is able to cope with especially complex forms of these diseases (acute otitis media, pharyngitis, tonsillitis).

Most often, Dicloberl comes in combination with other drugs. Thus, it gives the maximum possible effect from the procedures.

Contraindications

It should not be used if there is a stomach ulcer and 12 duodenal ulcer. Dicloberl is especially contraindicated in a chronic diagnosis or during an exacerbation of this disease.

Minor gastrointestinal bleeding is a good reason to choose something more suitable from analogues.

With oncological diagnoses, it also makes sense to reconsider the choice, in particular if there are tumors of the intestine or rectum.

For children under 6 years of age, Dicloberl is contraindicated in all its forms.

Upon reaching this age, in some cases, you can take pills, but under close supervision from the age of 15, in special cases, it is possible to use candles. From 18 - injections and Dicloberl Retord are allowed.

The presence of kidney and liver diseases in a chronic condition is also a good reason to switch to another drug.

Any type of violation of the maturation of blood cells (hematopoiesis).

Chronic lung diseases, including bronchial asthma.

Ischemia developed against the background of angina pectoris, as well as in the presence of myocardial infarction.

Brain diseases caused by pathological changes in cerebral vessels with impaired cerebral circulation, including a stroke that has occurred.

It is not advisable to use Dicloberl during pregnancy. In the last trimester, it is contraindicated categorically. Studies have shown that the use of this drug increases the risk of fetal cardiovascular disease. In the first and second trimesters, Dicloberl can only be taken if the expected benefit of the treatment prevails. But for treatment, you should drink the lowest possible dosage for the shortest possible time.

During lactation, the drug is not directly contraindicated, but it must be taken into account that diclofenac has the ability to penetrate into milk. With a short course of treatment, this will not entail any consequences. But with long-term use, it is still better to consider the possibility of stopping breastfeeding.

It is believed that Dicloberl reduces female fertility (the ability to get pregnant), so if a woman planning a pregnancy has difficulty conceiving, then it is better to consider replacing Dicloberl with its analogue.

Instructions for use

Dicloberl in ampoules

It should be injected deep into the gluteal muscle, slowly. One ampoule is equal to the daily rate. If the situation so requires, it can be increased, but not more than twice. In this case, it is better to take a break of several hours between injections.

Most often, injections are given only in the first few days after the onset of symptoms of the disease, to quickly and effectively relieve symptoms. In extreme cases, injections continue to be given further, but not more than 10 pieces. Further treatment is carried out using a different form, such as suppositories.

The daily intake of Dicloberl should not go beyond 150 mg. The optimal daily serving is 50 mg. If it requires an increase, then the tablets should be taken in several approaches. You need to take the pill with food, not forgetting to drink it with a small portion of warm water. Once the condition returns to normal, the daily intake should be reduced to 50 mg.

Children after 6 years of age in special cases are also prescribed Dicloberl in tablets, at the rate of a daily portion of 25 mg. You should know that the daily rate should not exceed 2 mg / kg. From this formula and repelled when building a treatment regimen.

Dicloberl capsules

One capsule of Dicloberl Retard per day is enough for the successful treatment of severe pain. In rare cases, this rate is doubled, bringing up to 200 mg. After the primary effect is achieved, the rate can be gradually reduced. First, up to 150 mg, drinking a capsule and a tablet per day, and then up to one capsule per day. It should be borne in mind that such a large dosage, although much more successfully taken to fight the disease, is much more likely to cause side effects. Therefore, this dosage is taken only under the close supervision of the attending physician.

The duration of treatment is adjusted by the doctor.

Dicloberl candles

Candles Dicloberl put in the rectum. If the patient has constipation, it is better to prepare the intestines for the procedure in advance, forcibly freeing them from feces. If these procedures are not carried out, then the effect of the treatment will be reduced. Usually the daily rate ranges from 50-150 mg. you need to enter candles for several procedures. In the future, the consumption rate is reduced to a candle per day. As a rule, treatment lasts no longer than five days.

Overdose

If you do not follow the instructions attached above, and do not adhere to the daily allowance, an overdose may occur. In what form does it appear?

First of all, dizziness may appear, up to fainting. There may be jumps in upward pressure, increased heart rate. Nausea and vomiting, accompanied by diarrhea, are not excluded. Cramps of the extremities, rashes on the skin in the form of red spots, pain in the liver and kidneys is not excluded. Gastric bleeding may open.

At the first signs of an overdose, you should wash the stomach, induce vomiting on your own. If a severe allergic reaction has begun, take a double dose of an antihistamine and call an ambulance.

Side effects

In various situations and depending on the "bouquet" of diseases, the patient may experience adverse reactions:

• Pressure fluctuations may occur. Sharp jumps in blood pressure are likely to increase. Pain in the chest area may be noted, as well as tachycardia.
• There may be a decrease in hemoglobin in the blood. The leukocyte count may also fall, against this background, the body's susceptibility to bacterial and fungal diseases increases.
• Nausea, vomiting, the development of gastric ulcers are only a part of the disorders that are noted on the part of the gastrointestinal tract.
• Perhaps the development of a depressive state, irritability, headaches.

To minimize such reactions, you need to undergo the most complete examination before the procedures. This will avoid possible problems and significantly reduce the likely risk of treatment.

Interaction

It is better not to take risks and not include other non-steroidal anti-inflammatory drugs in parallel with Dicloberl. This combination is fraught with subsequent stomach ulcers.

Phenytoin, Rifampicin - they accelerate the metabolic process, and can reduce the effect of treatment.

Diclofenac is able to almost halve the result of treatment with Colestyramine and Colestipol.

If it is impossible to exclude any of the drugs, you should take a break between procedures for a couple of hours.

Diclofenac is also prescribed with caution in diabetes mellitus. There are situations when, due to the intake of Dicloberl, the glucose content in the blood changed dramatically. Moreover, the readings can increase sharply and, on the contrary, fall below the norm.

Sulfinpyrazone and Probenecid are also best excluded during treatment with Dicloberl due to their ability to retain diclofenac sodium.

From taking drugs that weaken the ability of blood to coagulate and inhibit the formation of blood clots, you should also refuse. Since Dicloberl enhances the effect of such drugs.

A parallel course with drugs responsible for lowering pressure and diuretics can reduce the effectiveness of their administration. Such combinations should be prescribed with extreme caution, especially among the age contingent. Be very careful to ensure that the patient drinks enough water.

Carefully you need to take Dicloberl with potassium-sparing diuretics. with this combination, you need to constantly monitor the level of potassium in the body.

Analogues

Dicloberl has a lot of analogues, the most common of them is Diclofenac. It has the same release forms as its counterpart, plus it is also available in the form of a gel. Which greatly simplifies its use.

Quite often, Voltaren and Ketanov are prescribed. Their manufacturers have gone even further, in addition to injections, tablets, capsules, gels and suppositories, they even produce their preparations in the form of a patch.

Also similar are:

• Diklobru, Ketalgin - are available in the form of tablets and injections.
• Diclocaine - has only the form of stakes.
• Dicloreum - also has a fairly wide range of forms. It is sold in pharmacies in the form of injections, gel, suppositories and tablets.
• Dicloferol - has only the form of tablets.
• Ortofen - also has a wide range of forms and types.
• Remetan - is produced in the same forms as Dicloberl.
• Difen, Naklofen, Sanfinak, Tabuk Di, Feloran 25, etc., etc.

In fact, the list is endless. But it should be remembered, no matter how the drug is advertised, only a doctor can prescribe it and advise the most effective therapy.

special instructions

In view of the fact that one of the side effects of taking Dicloberl is dizziness, fatigue, which can cause the inability to concentrate, it is better to refuse to drive a car at this time.

Due to the fact that Dicloberl is an anti-inflammatory drug, it can unwittingly hide the appearance of infectious diseases.

With prolonged treatment, a headache may occur, in no case should you try to relieve the pain effect by increasing the dosage.

When mixing alcohol and diclofenac, the effect of the second on the gastrointestinal tract and nervous system is enhanced. This increases the risk of provoking side effects in these areas. During the course of diclofenac, doctors strongly recommend that you stop drinking alcohol-containing products.