Nose drops sanorin analergin. Sanorin allergodil
The active components of the drug Sanorin analergin - antazoline phosphate and naphazoline - have a concentration of 5 mg and 0.25 mg, respectively, per 1 ml of solution. Since Antazolin is a selective H1-receptor blocker by the mechanism of action, it is able to slightly narrow the capillaries, reduce their permeability and eliminate itching, due to which a pronounced anti-allergic, anti-inflammatory and anti-edematous effects of the drug appear. To reinforce these actions, naphazoline, which belongs to alpha-adrenergic agonists, significantly enhances vasoconstriction, due to which exudative phenomena are noticeably reduced, swelling and hyperemia of the superficial membranes of the eyes are removed. Auxiliary components of the drug Sanorin analergin are boric acid, methylparaben, disodium edetate and purified sterile water. Due to this composition, the solution of eye drops is completely absorbed during local application, which ensures a rapid manifestation of the therapeutic effect.
Indications for use
Due to its high efficiency in inflammatory and allergic eye diseases, Sanorin analergin is prescribed as a symptomatic component of complex therapy for allergic conjunctivitis and hay fever.
Contraindications
Contraindications to the use of Sanorin analergin eye drops are the presence of a history or current hypersensitivity to any of the components of the drug, children under 3 years of age, chronic rhinitis, as well as the period of treatment with MAO inhibitors (including within 14 days after it endings). With caution, this drug should be prescribed for angle-closure glaucoma, diseases of the cardiovascular system (arterial hypertension, heart failure II-III severity) and the endocrine system (thyrotoxicosis, pheochromocytoma, diabetes mellitus), as well as general anesthesia using anesthetics that increase sensitivity myocardium to sympathomimetics (halothane).
Overdose
In case of an overdose of the drug or its accidental ingestion, the following symptoms may appear: a decrease in body temperature, lethargy and drowsiness, bradycardia, arterial hypertension. Treatment: if necessary, gastric lavage and symptomatic therapy. With constant use in high doses, especially in elderly patients, it is also possible to deposit pigment granules on the iris of the eye, increase intraocular pressure, itching, burning and pain in the eyes, visual impairment. Treatment: drug withdrawal.
Side effects
When used within the recommended doses, mild side effects of Sanorin analergin may occur: allergic reactions, irritation, burning and dryness of the superficial membranes of the eyes and nasal mucosa, and immediately after instillation of the solution, mydriasis, blurred vision, followed by reactive hyperemia. In rare cases, systemic side effects are possible: nervousness, headaches, weakness, increased sweating, arterial hypertension, nausea, tremor, tachycardia.
Pregnancy and lactation
This drug is allowed to be used during pregnancy and lactation only if the expected effect of treatment exceeds the possible risk to the fetus and child.
Instructions for use and dosage
The drug Sanorin analergin is used conjunctivally 1 drop 3-4 times a day, in children over 3 years old - 1-2 drops 1 time a day.
Drug Interactions and Precautions
These eye drops should be used with caution in elderly patients with severe diseases of the cardiovascular and endocrine systems, in patients with angle-closure glaucoma who have not previously undergone iridoectomy or iridotomy, with chronic rhinitis. Since this drug has a sufficient systemic effect, it should be prescribed exclusively by an ophthalmologist, and during treatment patients should consult a doctor in case of anxiety, symptoms of eye irritation, visual acuity disturbance. When instilling the solution, it is necessary to engraft the projection point of the lacrimal canal to reduce the absorption of the drug into the systemic circulation.
When used simultaneously with local anesthetics, the drug slows down their absorption, and when co-administered with MAO inhibitors, the risk of developing arterial hypertension increases significantly.
Terms of dispensing from pharmacies
The drug is dispensed from pharmacies without a doctor's prescription. Keep the bottle out of the reach of children at a temperature not exceeding 25 C. Shelf life - 3 years, after opening, use within 1 month.
Additional components: boric acid, methyl parahydroxy-benzoate, disodium edetate and water.
Release form
Sanorin Analergin is produced in the form of nasal drops, packaged in dark 10 ml bottles with a rubber pipette.
pharmachologic effect
Drops are characterized by anticongestive, antihistamine, antiallergic and vasoconstrictive effect.
Pharmacodynamics and pharmacokinetics
As you know, the active component of the drug - naphazoline - is an alpha2-adrenergic agonist, capable of providing a quick, pronounced and lasting effect aimed at constricting the vessels of the nasal mucosa. This reduces swelling, exudation and hyperemia, facilitates nasal breathing during rhinitis. Tolerance may develop within 5-7 days.
Another active ingredient of drops - antazolin - refers to selective H1-histamine receptor blockers, which have anti-allergic, anti-edematous and anti-exudative effects.
The use of the drug leads to a decrease in swelling of the nasal mucosa and vasoconstriction, which manifests itself after 10 minutes and lasts an average of 4-5 hours. After applying the drops, they are absorbed into the systemic circulation directly through the nasal mucosa.
Indications for use
Drops are prescribed for:
Contraindications
You need to be careful when:
Side effects
If the drops are used in the recommended dosage, then usually there are no side effects. In rare cases, intolerance reactions may develop, for example, nausea, tachycardia, headache, irritability, allergic manifestations, rash, high blood pressure, and so on.
Instructions for Sanorin Analergin (Method and dosage)
As the instructions for the use of drops indicate, they are prescribed to patients from 16 years of age. During treatment 3-4 times a day, 2-3 drops are instilled into each nasal passage. The medicine is recommended to be used only for a short time, no longer than 7 days, after which they take a break.
Overdose
An overdose of this drug can lead to the development of nervousness, a decrease in body temperature, lethargy, drowsiness, bradycardia, sweating, and blood pressure failures. In this case, treatment is carried out, depending on the symptoms that appear.
Interaction
With the combination of naphazoline with some local anesthetic drugs, their absorption is slowed down, that is, the effect of such drugs is prolonged during surface anesthesia.
Combinations with MAO inhibitors may increase the risk of developing arterial hypertension, as there is a release of deposited catecholamines as a result of the action of naphazoline. The metabolism of antazolin in the liver also slows down, which enhances its effect.
special instructions
Sometimes this drug exhibits a resorptive effect.
Prolonged use of drops reduces the severity of the vasoconstrictor effect, the development of swelling of the nasal mucosa, gradually turning into atrophy, is not excluded. Therefore, experts recommend using drops for no more than 7 days, after which it is imperative to take a break.
Terms of sale
Storage conditions
Drops should be stored in a cool, dark place out of the reach of children.
Shelf life
Analogues
The main analogues of the drug: Alergoftal, Oftofenazole.
Reviews about Sanorin Analergin
As the reviews of Sanorin Analergin show, the inadmissibility of its use during pregnancy in some women in the position is in doubt. Moreover, sometimes even experts recommend these drops, arguing that there is nothing unusual in this. Many explain this approach by the fact that the annotation to the medicine does not exactly indicate that it is contraindicated during lactation and pregnancy.
According to the manufacturer, indeed, there is no data on harm to the fetus or baby, but it is also unknown that they are completely safe. Therefore, it would be more expedient at this time to abandon the use of such drugs.
Other patients who often suffer from allergies say that Sanorin Analergin is a good remedy that helps them to relieve the manifestation of unwanted symptoms. As a rule, people who have suffered from allergies for many years know perfectly well when and in what cases they need to use antiallergic drugs. They use drops during the flowering period, when communicating with animals, and so on - it all depends on what causes their allergies.
Thus, when allergy symptoms appear, it is necessary not only to choose the right medicine, but also to determine the cause of their occurrence, that is, to make the most of all possible ways to improve the body. In addition, Sanorin Analergin is contraindicated to use without the appointment of a specialist.
Price Sanorin Analergin, where to buy
You can buy drops in Russian pharmacies for roubles.
The price of Sanorin Analergin in Ukraine is 270 UAH.
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Sanorin-Analergin
Sanorin-Analergin: instructions for use and reviews
Latin name: Sanorin-Analergin
ATX code: R01AB02, S01GA51
Active ingredient: antazoline (antazoline), naphazoline (naphazoline)
Manufacturer: Teva Czech Industries s.r.o., IVAX-CR (Czech Republic)
Description and photo update: 12/06/2017
Prices in pharmacies: from 254 rubles.
Sanorin-Analergin - a drug for topical use in otorhinolaryngology and ophthalmology with antiallergic and vasoconstrictive action; blocker of H 1 -histamine receptors, alpha-adrenergic agonist.
Release form and composition
- nasal and eye drops: transparent colorless liquid (10 ml each in a dark glass bottle, in a cardboard box 1 bottle complete with a SANO rubber pipette with a cap);
- nasal drops: clear liquid, without color and mechanical inclusions (10 ml each in a dark-colored glass bottle, 1 bottle in a cardboard box).
1 ml of nasal and eye drops contains:
- auxiliary components: boric acid, methylparaben, sodium chloride, sterile water.
1 ml of nasal drops contains:
- active ingredients: naphazoline nitrate - 0.25 mg; antazolin mesylate - 5 mg;
- auxiliary components: disodium edetate, methyl parahydroxybenzoate, boric acid, water.
Pharmacological properties
Pharmacodynamics
Sanorin-Analergin is a combined antiallergic drug, the effectiveness of which is due to the action of its components:
- naphazoline: alpha 2-agonist, providing a rapid, prolonged and pronounced vasoconstrictor effect on the capillaries of the nasal mucosa, causes a decrease in swelling, exudation, hyperemia, and facilitates nasal breathing in rhinitis. After 120–168 hours of use, tolerance appears;
- antazolin: a selective blocker of H 1 -histamine receptors, has anti-allergic, anti-edematous and anti-exudative activity. The effect in the form of vasoconstriction and a decrease in swelling of the nasal cavity occurs 1/6 hour after instillation and lasts from 2 to 6 hours.
Pharmacokinetics
The absorption of active substances into the systemic circulation when applied topically occurs through the nasal mucosa.
Indications for use
According to the instructions, Sanorin-Analergin is indicated for the treatment of acute rhinitis, including allergic rhinitis and rhinorrhea.
Contraindications
- chronic atrophic rhinitis;
- severe atherosclerosis;
- tachycardia;
- arterial hypertension;
- hyperthyroidism;
- diabetes;
- concomitant therapy with monoamine oxidase inhibitors (MAO) and the period within 14 days after its completion;
- pregnancy and breastfeeding;
- age up to 16 years;
- hypersensitivity to the components of the drug.
Caution should be exercised when using Sanorin-Analergin, patients with pheochromocytoma, bronchial asthma, prostatic hyperplasia, coronary heart disease (angina pectoris); when combined with drugs that increase blood pressure; with inhalation anesthesia with agents that increase the sensitivity of the myocardium to sympathomimetic drugs (including halothane).
Instructions for use Sanorin-Analergin: method and dosage
Sanorin-Analergin is intended for instillation into the conjunctiva of the eye and intranasal use.
After a few days of interruption, the use of the drug can be resumed.
Side effects
- rarely: allergic reactions, nausea, headache, pain, irritability, tachycardia, increased blood pressure (BP), local irritation, rash, reactive hyperemia, swelling of the nasal mucosa;
- possible: against the background of frequent and prolonged use - edema, atrophy of the nasal mucosa.
Overdose
Symptoms of an overdose of naphazoline are a decrease in body temperature, drowsiness, sweating, lethargy, nervousness, bradycardia, an increase and decrease in blood pressure.
special instructions
Sanorin-Analergin may exhibit a resorptive effect.
Tachyphylaxis that occurs with prolonged therapy is manifested by the development of edema of the nasal mucosa, up to its atrophy. In order to prevent a pronounced decrease in the vasoconstrictor effect of the drug, it is required to take a break after every 5-7 days of using the drops.
Use during pregnancy and lactation
The use of Sanorin-Analergin during gestation and lactation is contraindicated.
If it is necessary to use the drug during lactation, breastfeeding should be interrupted and resumed after the drops are discontinued.
Application in childhood
It is contraindicated to use drops for the treatment of children under the age of 16 years.
drug interaction
When used simultaneously with Sanorin-Analergin:
- drugs for local anesthesia: naphazoline prolongs their action;
- MAO inhibitors: increase the risk of developing severe arterial hypertension.
Analogues
Analogues of Sanorin-Analergin are: Alergoftal, Adrianol, Vibrocil, Adrianol for children, Nazik, Xymelin, Oftofenazole, etc.
Terms and conditions of storage
Keep away from children.
Store at 10-25°C, protected from light. Cannot be stored in the refrigerator. Avoid freezing.
Shelf life - 2 years.
Terms of dispensing from pharmacies
Released without a prescription.
Reviews about Sanorin-Analergin
Reviews about Sanorin-Analergin are quite contradictory. For most patients, this is the drug of choice during allergy season due to its effectiveness. Drops quickly relieve congestion and swelling of the nasal cavity, facilitate nasal breathing and improve the general condition a few minutes after application. With eye instillations, puffiness and itching of the eyes are removed, intranasal use stops sneezing. Drops do not cause drying of the mucous membrane. Therefore, bitterness in the throat after instillation, these patients do not consider a significant drawback of the drug, compared with the debilitating sensations of the symptoms of the disease. The advantages of Sanorin-Analergin include the possibility of instillation both into the nose and into the eyes.
Patients dissatisfied with the quality of the drug also note the rapid effect of drops in relieving edema, but at the same time they indicate a strong burning sensation in the nasopharynx, pronounced side effects and the impossibility of long-term continuous use of drops during the allergy season.
The disadvantages of many include the inconvenient drip device of the bottle.
The price of Sanorin-Analergin in pharmacies
The price of Sanorin-Analergin for 1 bottle of nasal and eye drops can be from 270 rubles.
Sanorin-Analergin nasal drops 10ml
Education: First Moscow State Medical University named after I.M. Sechenov, specialty "Medicine".
Information about the drug is generalized, provided for informational purposes and does not replace the official instructions. Self-medication is dangerous to health!
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Sanorin-Analergin - official instructions for use
Registration number:
Trade name of the drug: Sanorin-Analergin &
International non-proprietary name or grouping name:
Dosage form:
Each vial (10 ml) contains:
Naphazoline nitrate - 2.5 mg, antazoline mesylate - 50 mg.
boric acid mg, methyl parahydroxy-benzoate - 10 mg, disodium edetate - 1 mg, water up to 10 ml.
Transparent colorless liquid without visible mechanical inclusions.
Combined antiallergic agent (H1-histamine receptor blocker + alpha-adrenergic agonist).
Naphazoline belongs to alpha2-adrenergic agonists, has a rapid, pronounced and prolonged vasoconstrictive effect on the vessels of the nasal mucosa (reduces swelling, hyperemia, exudation). Facilitates nasal breathing in rhinitis. After 5-7 days, tolerance develops. Antazolin is a selective blocker of H1-histamine receptors, has anti-allergic, anti-edematous and anti-exudative effects.
When applied topically, it is absorbed into the systemic circulation through the mucous membrane of the nasal cavity. There are no data regarding the distribution, metabolism and elimination of the drug Sanorin-Analergin.
The drug Sanorin-Analergin is indicated for the treatment of acute rhinitis, especially of allergic etiology; rhinorrhea.
Hypersensitivity to the components of the drug; arterial hypertension, severe atherosclerosis, hyperthyroidism, age up to 16 years, pregnancy, lactation, chronic atrophic rhinitis, diabetes mellitus; tachycardia; simultaneous reception of monoamine oxidase inhibitors (MAO) and a period of up to 14 days after the end of their use.
Pheochromocytoma, simultaneous treatment with drugs that increase blood pressure, the use of inhalation anesthesia, which increase the sensitivity of the myocardium to sympathomimetic drugs, including halothane, bronchial asthma, prostatic hyperplasia, coronary heart disease (angina pectoris).
Adults and children over 16 years of age
2-3 drops in each nasal passage 3-4 times a day. Apply briefly, no more than 1 week, then take a break for a few days.
At recommended doses, the drug is usually well tolerated. In rare cases, adverse reactions such as nausea, tachycardia, headache, irritability, allergic reactions, rash, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa, and local irritation may occur. With prolonged and frequent use, more than 1 week, swelling and atrophy of the nasal mucosa.
In case of an overdose of the drug as a result of systemic action, nervousness, a decrease in body temperature, lethargy, drowsiness, bradycardia, sweating, an increase in blood pressure, which may be replaced by a decrease in blood pressure, may develop. Treatment: symptomatic.
Interaction with other drugs
10 ml of the drug in brown glass bottles, equipped with a SANO rubber pipette with a polyethylene cap and a label. Each bottle is placed in a cardboard box with instructions for use.
In a place protected from light at a temperature of 10 to 25 ° C. Do not refrigerate or freeze. Keep out of the reach of children!
Do not use after the expiration date.
Registration Certificate holder in Russia
Teva Pharmaceutical Enterprises Ltd., Israel
Teva Czech Enterprises s.r.o., Czech Republic Ostravska 29, Opava-Komarov, Czech Republic
Claims address
119049, Moscow, st. Shabolovka, 10, building 2, Concord business center
Sanorin allergodil
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SANORIN-ANALERGIN
◊ Drops nasal and eye as a clear, colorless liquid.
Excipients: boric acid, sodium chloride, methylparaben, sterile water.
10 ml - dark glass bottles (1) with a SANO rubber pipette with a lid - cardboard boxes.
◊ Nasal drops transparent, colorless, without visible mechanical inclusions.
Excipients: boric acid mg, methyl parahydroxybenzoate - 10 mg, disodium edetate - 1 mg, water - up to 10 ml.
10 ml - dark glass bottles (1) - packs of cardboard.
Naphazoline belongs to alpha 2 -agonists, has a rapid, pronounced and prolonged vasoconstrictive effect on the vessels of the nasal mucosa (reduces swelling, hyperemia, exudation). Facilitates nasal breathing in rhinitis. After 5-7 days, tolerance develops.
Antazolin is a selective blocker of H 1 -histamine receptors, has anti-allergic, anti-edematous and anti-exudative effects.
When applied topically, a decrease in swelling of the nasal mucosa and vasoconstriction occur within 10 minutes and persist for 2-6 hours.
Treatment of acute rhinitis, especially allergic etiology;
Hypersensitivity to the components of the drug;
Age up to 16 years;
Chronic atrophic rhinitis;
Simultaneous use of monoamine oxidase (MAO) inhibitors and a period of up to 14 days after their completion
Carefully: pheochromocytoma, simultaneous treatment with drugs that increase blood pressure, the use of inhalation anesthesia, which increase the sensitivity of the myocardium to sympathomimetic agents, including halothane, bronchial asthma, prostatic hyperplasia, coronary artery disease (angina pectoris).
Adults and children over 16 years old: 2-3 drops in each nasal passage 3-4 times a day. Apply briefly, no more than 1 week, then take a break for a few days.
At recommended doses, the drug is usually well tolerated. In rare cases, adverse reactions such as nausea, tachycardia, headache, pain, irritability, allergic reactions, rash, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa, and local irritation may occur. With prolonged and frequent use, more than 1 week, swelling and atrophy of the nasal mucosa.
Symptoms: nervousness, decrease in body temperature, lethargy, drowsiness, bradycardia, sweating, increased blood pressure, which may be replaced by a decrease in blood pressure.
Naphazoline slows down the absorption of local anesthetic drugs (prolongs their action during surface anesthesia).
MAO inhibitors increase the risk of developing severe arterial hypertension (release of deposited catecholamines under the action of naphazoline), slow down the metabolism of antazoline in the liver - increased action.
May have a resorptive effect.
With prolonged use, the severity of the vasoconstrictor action gradually decreases (the phenomenon of tachyphylaxis), it is possible to develop swelling of the nasal mucosa with its subsequent atrophy, in this regard, it is recommended to take a break for several days after 5-7 days of use.
The drug Sanorin-Analergin should not be used by pregnant women and nursing mothers. In the event of pregnancy, the drug should be discontinued, if the drug is taken during lactation, breastfeeding should be interrupted for the entire period of treatment with Sanorin-Analergin.
In a place protected from light at a temperature of 10 to 25 ° C. Do not refrigerate or freeze. Keep out of the reach of children. Shelf life - 2 years.
To ask a question about the work of the project or contact the editors, use this form.
Active ingredients
Naphazoline nitrate (naphazoline)
- antazoline mesylate (antazoline)
Release form, composition and packaging
◊ Drops nasal and eye as a clear, colorless liquid.
Excipients: sodium chloride, methylparaben, sterile water.
10 ml - dark glass bottles (1) with a rubber pipette "SANO" with a cap - cardboard boxes.
◊ Nasal drops transparent, colorless, without visible mechanical inclusions.
Excipients: boric acid - 145 mg, methyl parahydroxybenzoate - 10 mg, disodium edetate - 1 mg, water - up to 10 ml.
10 ml - dark glass bottles (1) - packs of cardboard.
pharmachologic effect
Naphazoline belongs to alpha 2 -agonists, has a rapid, pronounced and prolonged vasoconstrictive effect on the vessels of the nasal mucosa (reduces swelling, hyperemia, exudation). Facilitates nasal breathing in rhinitis. After 5-7 days, tolerance develops.
Antazolin is a selective blocker of H 1 -histamine receptors, has anti-allergic, anti-edematous and anti-exudative effects.
When applied topically, a decrease in swelling of the nasal mucosa and vasoconstriction occur within 10 minutes and persist for 2-6 hours.
Pharmacokinetics
When applied topically, it is absorbed into the systemic circulation through the mucous membrane of the nasal cavity. There are no data regarding the distribution, metabolism and elimination of the drug Sanorin-Analergin.
Indications
- treatment of acute rhinitis, especially allergic etiology;
- rhinorrhea.
Contraindications
- hypersensitivity to the components of the drug;
- arterial hypertension;
- severe atherosclerosis;
- hyperthyroidism;
- age up to 16 years;
- lactation period;
- chronic atrophic rhinitis;
- diabetes;
- tachycardia;
- simultaneous use of monoamine oxidase (MAO) inhibitors and a period of up to 14 days after their completion
applications.
Carefully: pheochromocytoma, simultaneous treatment with drugs that increase blood pressure, the use of inhalation anesthesia, which increase the sensitivity of the myocardium to sympathomimetic agents, including bronchial asthma, prostatic hyperplasia, coronary artery disease (angina pectoris).
Dosage
Adults and children over 16 years of age: 2-3 drops in each nasal passage 3-4 times a day. Apply briefly, no more than 1 week, then take a break for a few days.
Side effects
At recommended doses, the drug is usually well tolerated. In rare cases, adverse reactions such as nausea, tachycardia, headache, pain, irritability, allergic reactions, rash, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa, and local irritation may occur. With prolonged and frequent use, more than 1 week, swelling and atrophy of the nasal mucosa.
Overdose
Symptoms: nervousness, decrease in body temperature, lethargy, drowsiness, bradycardia, sweating, increased blood pressure, which may be replaced by a decrease in blood pressure.
Treatment: symptomatic.
drug interaction
Naphazoline slows down the absorption of local anesthetic drugs (prolongs their action during surface anesthesia).
MAO inhibitors increase the risk of developing severe (release of deposited catecholamines under the action of naphazoline), slow down the metabolism of antazoline in the liver - increased action.
Naphazoline belongs to alpha 2 -agonists, has a rapid, pronounced and prolonged vasoconstrictive effect on the vessels of the nasal mucosa (reduces swelling, hyperemia, exudation). Facilitates nasal breathing in rhinitis. After 5-7 days, tolerance develops.
Antazolin is a selective blocker of H 1 -histamine receptors, has anti-allergic, anti-edematous and anti-exudative effects.
When applied topically, a decrease in swelling of the nasal mucosa and vasoconstriction occur within 10 minutes and persist for 2-6 hours.
Pharmacokinetics
When applied topically, it is absorbed into the systemic circulation through the mucous membrane of the nasal cavity. There are no data regarding the distribution, metabolism and elimination of the drug Sanorin-Analergin.Release form
Nasal drops are transparent, colorless, without visible mechanical inclusions.
Excipients: boric acid - 145 mg, methyl parahydroxybenzoate - 10 mg, disodium edetate - 1 mg, water - up to 10 ml.
10 ml - dark glass bottles (1) - packs of cardboard.
Dosage
Adults and children over 16 years old: 2-3 drops in each nasal passage 3-4 times a day. Apply briefly, no more than 1 week, then take a break for a few days.
Overdose
Symptoms: nervousness, decrease in body temperature, lethargy, drowsiness, bradycardia, sweating, increased blood pressure, which may be replaced by a decrease in blood pressure.
Treatment: symptomatic.
Interaction
Naphazoline slows down the absorption of local anesthetic drugs (prolongs their action during surface anesthesia).
MAO inhibitors increase the risk of developing severe arterial hypertension (release of deposited catecholamines under the action of naphazoline), slow down the metabolism of antazoline in the liver - increased action.
Side effects
At recommended doses, the drug is usually well tolerated. In rare cases, adverse reactions such as nausea, tachycardia, headache, pain, irritability, allergic reactions, rash, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa, and local irritation may occur. With prolonged and frequent use, more than 1 week, swelling and atrophy of the nasal mucosa.
Indications
- treatment of acute rhinitis, especially allergic etiology;
- rhinorrhea.
Contraindications
- hypersensitivity to the components of the drug;
- arterial hypertension;
- severe atherosclerosis;
- hyperthyroidism;
- age up to 16 years;
- pregnancy;
- lactation period;
- chronic atrophic rhinitis;
- diabetes;
- tachycardia;
- simultaneous use of monoamine oxidase (MAO) inhibitors and a period of up to 14 days after their completion
applications.
With caution: pheochromocytoma, simultaneous treatment with drugs that increase blood pressure, the use of inhalation anesthesia, which increase the sensitivity of the myocardium to sympathomimetic drugs, including halothane, bronchial asthma, prostatic hyperplasia, coronary artery disease (angina pectoris).
Application features
Use during pregnancy and lactation
The drug Sanorin-Analergin should not be used by pregnant women and nursing mothers. In the event of pregnancy, the drug should be discontinued, if the drug is taken during lactation, breastfeeding should be interrupted for the entire period of treatment with Sanorin-Analergin.
Use in children
Contraindicated in children under 16 years of agespecial instructions
May have a resorptive effect.
With prolonged use, the severity of the vasoconstrictor action gradually decreases (the phenomenon of tachyphylaxis), it is possible to develop swelling of the nasal mucosa with its subsequent atrophy, in this regard, it is recommended to take a break for several days after 5-7 days of use.
Allergy is one of the pathological conditions of the human immune system, manifested by an increased reaction to certain substances. Almost anything can play their role. Most often, allergens are plants, certain foods, dust particles. Less commonly, these are chemical compounds found in powders, cosmetics, and even odors. Unfortunately, the frequency of hypersensitivity reactions is increasing every year. The most common allergy symptoms are nasal congestion, runny nose, watery eyes, sneezing, and sometimes conjunctivitis. Usually these reactions appear in the spring and autumn periods. At this time, people begin to stock up on drugs to get rid of the symptoms of hypersensitivity, one of them is the drug "Sanorin-Analergin". The drug not only suppresses but also contributes to the normal tolerance of the active substance (for example, pollen).
Pharmacological effects of the drug
The drug is combined, as it contains two active substances. One of them is naphazoline nitrate. Its action is to narrow the vessels of the nasal mucosa. This reduces swelling and makes breathing easier. The second active ingredient is antazoline mesylate. It belongs to the group due to which allergic and inflammatory reactions of the body are suppressed. As a result of the combination of two drugs, the Sanorin-Analergin medication has the properties of each of them. We can say that this drug has anti-inflammatory, vasoconstrictive and antihistamine effects.
Indications for use
Due to the fact that the drug is combined, it can be used not only as a spray to improve breathing, but also instilled into the eyes. Despite the fact that the drug "Sanorin-Analergin" is called, it is also used in the absence of a hypersensitivity reaction. Indications for the use of the drug are:
- Rhinitis is an inflammation of the nasal mucosa, resulting in discomfort, congestion and runny nose. In this case, it is necessary to purchase an intranasal form of the drug. Nose drops "Sanorin-Analergin" qualitatively and quickly relieve swelling of the mucous membrane, after which the condition improves significantly. They can be used not only for allergic forms of rhinitis, but also for nasal congestion of viral etiology.
- Conjunctivitis - inflammation of the mucous membrane around the eyes - is also an indication for the use of Sanorin-Analergin drops. But in this case, the drug is not used as the main drug, but as an additional medication. Due to its action, the drops relieve inflammation and swelling of the conjunctiva.
Dosage of the drug
The drug is available in the form of drops, the package contains a rubber pipette for intranasal administration of the drug. To reduce nasal congestion and runny nose, it is necessary to apply the medication 3-4 times a day. The drug is injected with a pipette alternately into each nasal passage, 2-3 drops. If an allergic reaction is also manifested by conjunctivitis, then the drug can also be used in the eyes. The frequency of use is the same as when instilled into the nose. When using the drug "Sanorin-Analergin" for children, its dose is 1-2 drops in each nasal passage. The use of the drug is indicated for persons who have reached the age of 2 years. It is necessary to use the drug for no more than 7 days, if the symptoms persist for a longer period, then you need to take a break in the use of the drug.
Contraindications for use
The drug can not be used for diseases of the cardiovascular and endocrine systems in the stage of decompensation. The main contraindications are severe arterial hypertension, atherosclerosis, diabetes mellitus, hypothyroidism. Also, drops are not used in the chronic form of rhinitis, since their effectiveness decreases, and the prognosis of the disease does not tend to improve. One of the main contraindications is a hypersensitivity reaction to both the main and additional substances of the drug. The drug is undesirable for use in severe tachycardia. The interaction of this drug with MAO inhibitors is also a contraindication. The effect of drops on pregnant and lactating women has not been studied.
The drug "Sanorin-Analergin": reviews of doctors and patients
According to doctors, a combination of substances from two pharmacological groups is successful for the treatment of hay fever and conjunctivitis. Patients note not only the disappearance of symptoms, but also the ability to normally tolerate the action of the allergen. In most cases, side effects are not observed, and the reviews about the medication are positive.
The drug "Sanorin-Analergin": analogues
It is known that the drug is used in otolaryngology as a vasoconstrictor and anti-inflammatory agent. Therefore, it can be replaced with a preparation containing one of the constituent active substances - Nafazalin drops. Indications for the use of an analogue is rhinitis of various etiologies. Despite the fact that the drug "Nafazolin" does not contain an antihistamine component, it can also be used in hypersensitivity reactions as a symptomatic therapeutic agent. In this case, in addition to drops, antiallergic drugs should be used. The drug is available in 2 dosage forms. It should be remembered that Nafazolin drops are used from the age of 2, and the spray - from 15.
Another analogue is the well-known drug Naphthyzin. It has the same active substance as the drug "Nafazolin", so the indications for use and the mechanism of action of both are identical. The drug is used not only for difficulty breathing, but also as an anti-inflammatory agent for conjunctivitis. In this case, the dosage is reduced to 1-2 drops in each eye. Analogues are not inferior in efficiency, but due to the lack of an antihistamine component, they have a low cost.