Does metronidazole help chlamydia? Dosage of metronidazole for chlamydia

Urogenital chlamydia is an infection with the protozoan Chlamydia trachomatis.

The causative agent can stay in the body for a long time without causing pronounced or specific signs of acute or chronic infection.

Since chlamydia can provoke inflammatory processes in the small pelvis and worsen reproductive health in the future, all women who do not have a permanent sexual partner, and who are planning pregnancy in the near future, should be routinely examined.

The persistence of chlamydia in the female body is not always accompanied by a vivid clinical picture, however, infection can be suspected if the following symptoms are present:

• pulling, aching pain in the lower abdomen;
• non-physiological transparent discharge, regardless of the day of the cycle;
• painful intercourse;
• violation of the process of urination.

If an obstetric history is complicated (miscarriage, non-developing pregnancy or infertility) or an inflammatory process of the genitourinary system (adnexitis, cervicitis, endometritis, urethritis) is recorded, it is also imperative to consult a specialist.

If a chlamydial infection is suspected, a woman should consult a gynecologist for a specific diagnostic method.

A standard smear for purity is not capable of confirming or refuting the presence of this pathogen with sufficient efficiency.

The combination of PCR methods and bacteriological culture with the determination of sensitivity to antibiotics is considered optimal.

If the infection is confirmed, the gynecologist prescribes the appropriate treatment in the form of antibiotic therapy suitable for this patient.

To eliminate chlamydia, a course of a suitable antibiotic is prescribed to both sexual partners, where an important condition is protected sexual intercourse for a period until complete recovery.

In parallel, to suppress a concomitant anaerobic infection, an antimicrobial agent is taken, most often based on metronidazole or other nitroimidazoles with confirmed resistance to the first substance.

For the treatment of chlamydia, macrolide and tetracycline antibiotics are used, since they have the maximum ability to infect intracellular microorganisms and any form of protozoa - both in their active state and in the latent phase.

Decisive in choosing an antibiotic are not so much its properties, but the individual sensitivity of the chlamydia of a particular patient to the active substance.

This type of microorganisms cannot synthesize energy on their own, they are completely dependent on the host cell. It is this feature of chlamydia that determines the main route of infection transmission - sexual (in rare cases - hematogenous, contact-household).

The prevalence of chlamydia in men is up to 4%, while up to 30% of urethritis is associated with chlamydial infection. However, only people with severe symptoms seek medical help, which leads to an increase in the number of sick and infected people.

Causes of infection with chlamydia can be:

1. Lack of barrier methods during intercourse with an “unverified partner”.
2. Decreased protective reserves of the body (in immunodeficiency states).
3. The latent course of the disease (without clinical signs) in the partner.

Clinical symptoms

Signs of chlamydia in men can be tracked by certain symptoms.

The disease is characterized by:

1. Itching in the urethra.
2. Burning, pain when urinating (urine may be cloudy).
3. Light, almost colorless discharge from the urethra.
4. Frequent urge to urinate.
5. Redness and slight swelling in the area of ​​the urethral outlet.
6. Swelling, severe pain, local fever in the scrotum.
7. Pain in the scrotum, rectum.
8. Pain in the lumbar and sacral regions, and even in the lower extremities (along the sciatic nerve).
9. Reiter's triad is possible: urethritis, conjunctivitis and arthritis. As a rule, one of the large joints is affected unilaterally (for example, the knee, hip or ankle).
10. Discomfort during the act of defecation (typical for damage to the rectum and prostate).

For effective treatment of chlamydia in men, it is necessary to influence the causative agent of the disease.

In the primary acute process, good results were shown by antibacterial drugs from the group of macrolides ("Azithromycin", "Clarithromycin", "Josamycin", "Midecamycin") and tetracyclines ("Doxycycline").

However, treatment with drugs from a number of tetracycline antibiotics has several disadvantages:

1. The course of treatment for 1 week does not allow to achieve the desired result. According to studies, recurrence of the disease occurs in 15-20% of cases with this treatment regimen.
2. Lengthening the time of taking drugs up to 14 days is dangerous for the re-development of infection in 15% of cases.
3. Treatment for 21 days avoids relapses, as there is an effect on 7 cycles of development of the infectious agent. However, such a long-term regimen is inconvenient for patients: there is often a violation in taking antibiotics. Skipping pills, the irregularity of their use can lead to the formation of resistance (resistance) of chlamydia to this drug. In addition, prolonged use of drugs can provoke the development of a fungal infection, as well as dysbacteriosis of the digestive tract. To prevent these complications, it is necessary to prescribe antifungal drugs (Nystatin, Levorin, Ketoconazole), as well as eubiotics (Linex).

Given the above disadvantages of antibiotics from the tetracycline group, the most convenient treatment is macrolides.

The drug "Azithromycin" ("Sumamed") has a particularly high efficiency.

Advantages of the drug "Azithromycin":

1. A convenient treatment regimen is a single dose of 1 g of Azithromycin.
2. The effect of the drug lasts 10 days even after a single dose (this effect is created due to the half-life).
3. A simple scheme ensures 100% compliance with the doctor's recommendations.
4. "Azithromycin" is stored for a long time in the tissues affected by the inflammatory process.
5. Low percentage of side effects.
6. The antibiotic acts on intracellular pathogens due to the ability to accumulate inside cells (in particular, phagocytes). This is very important in the treatment of chlamydia, since chlamydia is completely dependent on the host cell.

So, if you carefully choose a drug and think about how to effectively cure chlamydia in a man, the drug "Azithromycin" ("Sumamed") is best suited - an antibiotic that fully meets the requirements for the treatment of chlamydia.

The chronic form of the disease is much more difficult to treat effectively and is dangerous for the occurrence of relapses.

Preference is also given to antibiotics from the group of tetracyclines and macrolides.

The following treatment regimens are effective:

1. Continuous reception of "Doxycycline" 200 mg 2 r / day for 28 days.
2. The method of pulse therapy consists in 3-fold administration of tetracyclines for 10 days with a break of 7 days. This scheme allows you to influence resistant intracellular strains of bacteria, affecting all cycles of development.
3. Reception "Azithromycin" 500 mg 2 times a day for 5 days (or 7 days with a long, often relapsing course of the disease).

Be sure to prescribe along with the use of etiotropic treatment:

1. Eubiotics ("Linex", "Bifiform")
2. Anti-candida drugs ("Nystatin", "Fluconazole").
3. Immunomodulators ("Polyoxdonium", "Interferon-Alpha").

In addition to pain in the affected organs and tissues, there are also long-term consequences:

1. Chlamydial infection in 30% is the cause of male infertility.
2. With a long course of the disease without proper treatment, the formation of chronic pelvic pain syndrome is possible.
3. Chlamydia can cause erectile dysfunction (when the infection spreads to the prostate).

Chlamydial infection is very "insidious", since in most cases it is almost asymptomatic or "masked" in the form of banal cystitis and urethritis. However, the consequences of this disease can be extremely serious.

Lack of timely treatment of chlamydia can cause irreversible changes in reproductive function (development of infertility). For this reason, it is necessary to follow the principles of "protected" sexual intercourse, and if alarming symptoms occur, be sure to consult a doctor to prescribe a competent and effective treatment.

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The list of drugs is quite large, each of them performs its function and helps to achieve quick results in the treatment of chlamydia.

These tablets for chlamydia are taken once, and are effective macroliths. They will give the best result at the beginning of the disease, the drug accumulates in the affected cells, killing chlamydia. True, it does not combine well with other drugs, the intake of which is necessary to restore the microflora. Azithromycin for chlamydia is prescribed with caution if:

• The work of the kidneys and liver is disturbed;
• There is an allergic reaction to macrolides.

Azithromycin tablets for chlamydia can be given with antimicrobials and probiotics.

Doxycycline

It belongs to the group of tetracycline antibiotics. Penetrating into the microorganism, in this case chlamydia, the drug inhibits its development, but does not affect the fungal or viral infection that usually accompanies chlamydia. Therefore, doxycycline in chlamydia is always prescribed in combination with other antibiotics (for example, with the same azithromycin). Dosage form - capsules or powder for intravenous injection.

Metronidazole

Chlamydia often gives rise to other concomitant infections, such as trichomoniasis and gardnerellosis. The drug is rapidly absorbed into the blood and accumulates in it. The concentration necessary for the death of Trichomonas is reached quickly.

Trichopolum

Medicines and treatments for chlamydia

Infectious diseases trichomoniasis and chlamydia are very similar, but at the same time, they have slightly different clinical manifestations and features of therapy. This article will tell about what trichomoniasis and chlamydia are, how to treat them.

Trichomoniasis is a very common acute infectious disease. The main way of infection with them is unprotected sexual intercourse (traditional sex) with the carrier of the infection. As for the transmission of the disease through oral or anal sex, this is unlikely.

Important! Trichomoniasis is a sexually transmitted infection. For this reason, they cannot be infected through shaking hands, sharing utensils or kissing.

Despite this, there is a small risk of transmission of the disease when using someone else's underwear, using a wet washcloth, towels and visiting the bath. This is justified by the fact that Trichomonas is able to actively live in a humid environment for several more hours.

In the event that the infection with this disease occurred in a domestic way, then, as a rule, a person does not even know about it and finds out during a routine diagnosis. In most cases, then the infection has already acquired a chronic form.

After the penetration of Trichomonas into the human body, the incubation period begins. It lasts for 2-3 weeks. At this time, pathogenic bacteria adapt to a new habitat, after which they begin to actively make themselves felt.

During the incubation period of the bacterium, the patient does not feel any signs of the disease.

As for chlamydia, it is also an infectious pathology, sexually transmitted. It is characteristic that the causative agents of this infection - chlamydia, can affect not only the genitals (vagina, cervix), but also the rectum, urethra in men and eyes.

Carefully! Chlamydia is considered an extremely common disease.

According to studies, it is observed in 10% of people under thirty who are sexually active.

Most susceptible to this infection are those people who often change sexual partners and practice sex without barrier contraception (condom).

You should know that the most common chlamydia infection occurs during intimate intercourse (traditional or anal, it does not make much difference, since the probability of transmission of the infection is equally high in both cases).

In addition, chlamydia can also be transmitted from mother to newborn child through sexual contact. In this condition, the baby has a high risk of developing pneumonia and eye diseases.

The household route of transmission of such an infection is not excluded, but it is unlikely. This is justified by the fact that these pathogenic bacteria die very quickly when they are outside the human body.

Moreover, for a full-fledged infection, it is necessary that a large number of active chlamydia penetrate the body. Otherwise, infection will not occur.

After chlamydia enters the body, the incubation period begins. It may take one to three weeks for the first symptoms to develop.

Manifestations and general symptoms of trichomoniasis are not much different from traditional pathologies of the genitourinary system. Moreover, very often this infection is confused with gonorrhea, since the signs of these pathologies are also quite similar.

Reference! A very important role in the features of the manifestation of trichomoniasis is played by the form of its course. Thus, a person can have an acute infection, a chronic infection, and a condition such as a carrier state, when a man or woman does not get sick themselves, but can infect other people.

The acute type of infection is manifested by pronounced symptoms.

In men, the acute form of this disease can provoke the following symptoms:

• Weakness and pain when urinating.
• Decreased sex drive and prostate problems.
• Burning during intimate intercourse.
• The appearance of unpleasant discharge from the urethra, which most often occurs in the morning.
• Fever and fever occurs with a weakened immune system, when infections are very easy to infect the body.

In the chronic form of the course, trichomoniasis has the same symptoms as in the acute one, but they are mild and the person may not even pay attention to them.

As a rule, the chronic form of such a disease is detected already when it began to cause dangerous complications. That is why infectious disease specialists strongly recommend regularly taking a preventive test for trichomoniasis, even if a person, at first glance, is not bothered by any signs of pathology.

In the event that a person is only a carrier of such a disease, then the least harm is done to his body. Thanks to a strong immune system, he will not suffer from the consequences of trichomoniasis, however, in the event of a sharp decrease in immunity, the disease can again become acute.

Chlamydia (trichomoniasis, its symptoms are very similar to this disease) is characterized by a sluggish course, so most patients learn that they are infected by accident.

This infection can occur in acute and chronic forms, each of which has its own symptoms.

During an acute course, men may develop the following signs of the disease:

• Hyperemia of the urethra and its severe inflammation.
• Swelling of the head of the penis.
• The appearance of unpleasant mucous or purulent discharge from the urethra.
• Pain when urinating.
• General deterioration of health and fever.
• Weakness.

Attention! In advanced form, chronic chlamydia in men will not cause acute symptoms, but it can provoke the development of prostatitis, proctitis and urethritis.

In women, acute chlamydia usually presents with the following symptoms:

• Discomfort during intercourse and pain during urination.
• Inflammation of the genitals.
• Drawing pain in lower abdomen.
• The appearance of vaginal discharge, which has a specific character.

Carefully! Untreated chlamydia, both in men and women, can cause a very dangerous complication in the form of infertility.

That is why it is important to respond to its manifestations in time and treat this disease.

It should also be noted that sometimes such an infection for a long time may not manifest itself at all, that is, proceed without symptoms. For this reason, every six months, both sexual partners need to take a preventive analysis.

Chlamydia treatment

Treatment when chlamydia is detected largely depends on the form of the disease, its neglect, symptoms and the presence of concomitant pathologies in a person. Thus, therapy is selected for each patient individually.

Treatment of chlamydia is aimed at suppressing the activity of chlamydia and preventing the development of dangerous complications.

At the same time, it is worth remembering that chlamydia themselves are highly resistant to many drugs, so the doctor must supervise the therapy and replace the medicine with another if it is not effective enough.

To eliminate chlamydia, you can use the following drugs:

1. Medicines Doxycycline and Azithromycin. They are most often used to treat chlamydia. Usually, they are prescribed in combination and used for several weeks.
2. Macrolide antibiotics (Rifampicin) are considered very effective. The duration of their intake in acute infections should be at least two weeks. In the case of a chronic disease, a person needs to take such drugs in courses.
3. For general support of the body, the patient must be prescribed immunomodulatory drugs.
4. Additional drugs that can be prescribed for chlamydia are: Kladitz, Metaklin, Lomefloxacin. Dosage and method of administration is selected separately for each patient.

It is impossible to self-medicate the disease.

Treatment of trichomoniasis

The regimen for taking these drugs and the duration of treatment is selected individually for each patient.

Also, as a supplement, local and symptomatic therapy can be carried out.

Conclusion

Chlamydia and trichomoniasis, the treatment of which must be controlled by a doctor, requires maximum endurance and patience from the patient, since general therapy is often lengthy and complex.

The topic of chlamydia treatment is quite important, since the spread and complications of the infection can significantly affect the health of men and women. The article discusses the drugs used for chlamydia and their effect on the body.

What is this disease?

This is an infectious disease. The causative agent of this pathology is a microorganism such as chlamydia. The prevalence of infection is quite high. Most often it is detected in women and men at a young age.

When they enter the body, they are located intracellularly in it, which provides a kind of protection against the action of various drugs, as a result of which the correct choice of medicines, in particular antibiotics, is very important for the treatment of chlamydia. Also, the pathological effect of the pathogen is based on the launch of a complex of inflammatory reactions in the area of ​​the affected cells of the body, which also explains the use of antibiotics.

The disease develops most often after sexual contact with an infected person. You can also get sick with oral-genital contacts, when after a while there is the development of inflammatory reactions in the eye area, the posterior pharyngeal wall.

A variant of the disease is possible as a result of non-compliance with hygienic care after sexual and other types of contact.

Chlamydia is characterized by its detection not only in adult men and women, but, unfortunately, in children, even newborns. This option is possible when the disease of the pregnant woman herself and the subsequent infection of her child during childbirth. It was also found that the pathogen is able to penetrate from a sick expectant mother to a child through the placental organ.

Main features

• Release form and composition
• Price and analogues
• pharmachologic effect
• Indications of Metronidazole
• For adults
• Is metronidazole given to children with giardiasis?
• Contraindications and side effects
• Ornidazole or Metronidazole - which is better for giardiasis?
• Reviews

Treatment of chlamydia in women: features of therapy and the most popular drugs

Main features

It is important to emphasize that the presence of timely therapy can also reduce the duration of the medication, if, of course, there is no spread of the disease to neighboring organs.

Treatment regimens

The main drugs for the treatment of chlamydia are Antibacterial. They are prescribed in order to cope with the source of the disease of chlamydia, which, as already noted, has an affinity for the cells of the human body and lives inside them.

It should be noted that not all antibiotics are prescribed for treatment. To treat chlamydia, drugs are needed that can penetrate the cell wall and affect the microbe that lives inside.

If the doctor recommends Doxycycline, then it should be taken 1 tablet twice a day for one week, maximum 10 days. If Azithromycin is recommended for the treatment of the disease, then its frequency of administration is 1 time per week at a dose of 1 gram for 3 weeks. This treatment regimen for chlamydia is typical for combined lesions of the pelvic organs. The course of treatment of the disease with the defeat of only its upper sections can be limited to only 1 gram once.

As an alternative treatment for the disease, antibiotics such as Erythromycin, Roxithromycin and Ofloxacin are prescribed. All these medicines must be taken for 10 days. Sometimes, for the treatment of the disease, a course of treatment is prescribed, which consists of taking Josamycin half a gram for 7 days three times a day.

If there are complications, then these alternative antibiotic preparations are prescribed for 14 days or 20 days.

Prescribing antibiotics is also important for the treatment of pregnant women. However, not all drugs are approved for use during pregnancy. The treatment regimen for chlamydia in this case consists of taking either Spiramycin, or Josamycin, or Amoxicillin. Sometimes prescribed drugs for treatment, such as Erythromycin and Azithromycin.

Spiramycin is taken for 7-10 days. Josamycin is prescribed for 7 days three times a day half a gram. Azithromycin is prescribed only 1 time 1.0 grams. Amoxicillin is prescribed for 7 days, three times a day after eight hours, half a gram. If Erythromycin is chosen for treatment, then it must be drunk for 7 days, but then four times a day and half a gram every six hours.

All drugs for treatment are effective, but Spiramycin is more often prescribed.

All of these medications for therapy should be taken after 14 weeks of pregnancy. In such a period, the organs of the unborn child have already been formed and taking antibiotics is relatively safe.

For the treatment of children, the choice is given in favor of such antibiotics as Azithromycin, Josamycin and Erythromycin.

Josamycin is used for 10 days after eight hours, based on the body weight of the child. Azithromycin is used to treat either 1 time 1 gram of the drug or 1 gram once for three days. Erythromycin is used for 14 days after six hours, also based on body weight.

Treatment of chlamydia is a very important and necessary moment for maintaining health. And after all the tests have been done, and the doctor has confirmed the alleged diagnosis of the disease, you should not postpone taking the medicine.

Why is the treatment of chlamydia so necessary? Why is it necessary to take all prescribed drugs? After all, sometimes the disease does not bother itself. Why, in this case, it is necessary to treat it and drink courses of antibiotics?

The presence of chlamydia is an insidious condition of the body. For this disease, which may not manifest itself in any way, unpleasant complications and consequences are typical.

If a course of treatment for chlamydia is not prescribed, then there is a high probability of the formation of such a disease in women as cervicitis, endometritis, in men - prostatitis, orchitis. It is worth recalling such a complication of chlamydia as salpingitis, salpingoophoritis. Also, do not forget about such a complication as pelvioperitonitis, which is manifested by temperature and accumulation of serous effusion.

Any doctor can tell you about another unpleasant consequence of the lack of treatment for chlamydia - this is infertility. Infertility can be not only as a result of the development of adhesions, sclerotic processes, but sometimes it is even possible to identify its hormonal type.

What is the treatment regimen for chlamydia when the doctor and tests reveal complications of the infection?

For the treatment of this type of chlamydia, antibiotic regimens are also prescribed. Most often, the doctor will recommend drugs such as doxycycline or azithromycin. The treatment time for the infection will be from two weeks. If the patient has an intolerance to these antibiotics, then they are replaced with Josamycin or Ofloxacin. You can also take Erythromycin.

Sometimes prescribed Azithromycin intravenously. This method is a fairly effective way to treat chlamydia. Often, to enhance the effect, the doctor may add a medication such as Metronidazole for seven days, 250 mg each.

How can they affect the course of chlamydia treatment?

The fact is that in women and in men, after infection with this disease, immunity will invariably suffer. The persistence of the infection in the patient's body leads to its weakening and the inability to actively fight it. And these drugs are able to activate all the defenses and help defeat the disease. Most often, the doctor prescribes drugs such as Imunofan, Cycloferon, Polyoxidonium and others.

It is recommended to use these drugs for the treatment of chlamydia not after the main treatment, but a few days before the start of antibiotics. This will provide a boost in immunity, which is very necessary to fight infection.

Also in the treatment of pathology, both in men and women, after the main course of treatment, vitamin-mineral complexes are recommended. Antioxidants in the form of vitamin E and C have a good property.

If the tests performed indicate liver disorders, then it is recommended to take drugs such as Hepatoprotectors. Such as Karsil, Essentiale are widely popular.

Thus, the full course of pathology therapy includes the following drugs:

1. Immunomodulating agents that help strengthen the body's defenses and are aimed at fighting infection
2. Antibacterial medicines that are prescribed after a course of immunomodulators. If a complicated course of the disease is detected, then 2 types of antibiotics are recommended.
3. Parallel intake of Hepatoprotectors, vitamins and antioxidants, which have a beneficial effect on the course of treatment and also strengthen the body
4. A good helper for the restoration of microflora after therapy is a group of medicines belonging to Probiotics. This group is a good nutrient medium for the growth of normal intestinal microflora after the treatment of chlamydia.

As we know, to identify the correct diagnosis, it is necessary to pass the appropriate tests. The time that must necessarily elapse since the end of treatment is estimated at one month. That is, it makes no sense to re-pass a laboratory test earlier and the results obtained may be incorrect.

Also important is the reduction and complete disappearance of all disturbing symptoms of inflammation, all the signs that appeared in patients and led to a doctor's appointment.

It is very important to complete the full course of medication, use them exactly as many days as the doctor recommends. At the time of treatment, it is desirable to exclude all sexual contacts or by all means use barrier means of protection, in the form of condoms.

Also, no less important, if one of the partners has chlamydia, then both should undergo a course of therapy in order to avoid re-infection.

If even one month after treatment you take tests, and the results still indicate the presence of a chlamydial infection in the body, then there is no need to panic. It is imperative to consult with your treating doctor, and, if necessary, undergo additional examination methods and a second course of therapy.

Treatment regimens

The relevance of the use of Metronidazole

Metronidazole is a highly active antimicrobial drug with a wide spectrum of activity for the treatment of diseases caused by anaerobic pathogenic bacteria, as well as some infectious pathologies caused by protozoa (with giardiasis, trichomoniasis, etc.). There are indications for treatment with Metronidazole for celiac pathologies, women's diseases, for dentistry and in other areas.

In addition, it is used not only as an agent with antibacterial properties. It is also in demand as an auxiliary medicine that improves the effectiveness of radiation treatment. It is used as an effective radiosensitizing agent. Possessing the ability to easily penetrate and penetrate into the tissues and cells of the human body, it enters the tumor, sensitizing its cells, as a result of which their sensitivity to radiation treatment increases.

Wide indications for the use of Metronidazole in gynecology.

1. It is recommended for the treatment of endometritis that develops after childbirth. It is often taken concomitantly with aminoglycosides. In severe, advanced endometritis, as well as for the treatment of infected abortion, Metronidazole regimens with fluoroquinolones are recommended.
2. The drug is also relevant in the treatment regimens for postpartum septic complications, with the formation of peritonitis that develops after a cesarean section.
3. Vaginosis of a bacterial nature is also a direct indication for Metronidazole therapy. Their reason is a violation of the physiological balance between representatives of the normal and conditionally pathogenic microflora of the vagina. This can happen in any pathological conditions in the body, leading to a decrease in immunity. As a result, the volume of conditionally pathogenic microflora increases while the normal one decreases. So, for example, reproduction and an increase in the number of opportunistic Gardnerellaspp are diagnosed. A decrease in its amount after antibiotic therapy indicates the normalization of the general microflora of the vagina.

Metronidazole is widely used in the treatment of vaginal dysbiosis (bacterial vaginosis)

Metronidazole is taken according to indications in gynecology, both as tablets and intravenously, as well as in suppositories for vaginal use.

Metronidazole tablets are not effective in the treatment of many worms. It does not work in relation to such worms as roundworms, tapeworms, pinworms and others. However, Metronidazole tablets show high efficiency in the fight against representatives of the simplest worms, that is, with amoebiasis, trichomoniasis, giardiasis, balantidiasis.

As a rule, in the treatment of protozoa and worms, tablets and capsules are taken. Indications for intravenous administration of Metronidazole from unicellular and worms are extremely rare, only in severe conditions.

When infected with trichomoniasis, Metronidazole is indicated for both treatment and prevention of infection. There are several schemes for getting rid of the simplest with this drug. To this day, it remains the most popular. However, almost 5% of all patients found that Trichomonas is not sensitive to this drug.

With amebiasis, Metronidazole tablets are effectively used in treatment regimens for adult protozoa, but treatment with this drug is ineffective if cystic carriage occurs.

He treats balantidiasis as part of complex therapy.

With chlamydia, Metronidazole tablets can be used in combination with other drugs. Against chlamydia, as such, Metronidazole is not active, however, it can be prescribed for chlamydia in order to suppress the accompanying flora, which can be activated when its balance is disturbed, provoked by protozoa.

The medicine is produced in the form of flat-shaped tablets.

Useless if you need a direct impact on chlamydia and worms, Metronidazole for giardiasis is the main component of complex treatment.

Two treatment regimens are used for them with giardiasis:

• 0.5 g three times a day for 5 days;
• 0.5 g for 10 days.

Dosage for children is calculated taking into account body weight: 5 mg / kg body weight three times a day.

Metronidazole is also used in dentistry. Tablets are prescribed as monotherapy or as a component of complex antibiotic therapy, for example, with Amoxicillin. They are widely used in the treatment of mixed (aerobic and anaerobic) infections in dentistry. For example, these drugs can be prescribed together or as monotherapy in dentistry for inflammatory and purulent lesions of the periodontium.

The most common drug of the imidazole group in dentistry is metronidazole.

In surgical dentistry of the maxillofacial area, Metronidazole is also actively used as a drug with a wide spectrum of antimicrobial activity as a treatment and prevention of postoperative complications.

Metronidazole is one of the drugs of therapy in the treatment of gastric and duodenal ulcers in order to get rid of one of its main culprits H. pylori.

The treatment of these pathologies of the gastrointestinal tract always requires an integrated approach. Monotherapy with any antibiotic is not effective. There are several treatment regimens. The most effective are the complex of Metronidazole with Clarithromycin. Combinations of Metronidazole with macrolides or b-lactams (ampicillin) are also relevant. Proton pump inhibitors are required for all schemes.

Pseudomembranous colitis. Metronidazole is active against Clostridium difficile. Therefore, it is widely used in the treatment of pseudomembranous and necrotizing colitis. It works bactericidal.

Successfully applied Metronidazole and topically: ointments, creams, gels. Indications for the use of such forms: purulent foci on the skin, sluggish wounds.

Metronidazole is most often tolerated without complications. But sometimes there are side effects. They are similar to those of other antibiotics.

This is an unpleasant taste of metal in the mouth, headache, impaired coordination of movements. Most often, patients complain that they feel sick. Sometimes nausea without subsequent vomiting. But with the correct use of the drug, as a rule, it does not feel sick and complications of the gastrointestinal tract are rare. Nausea, as a rule, when the recommendations for use are not followed, when it is taken longer than the recommended time or in large dosages. But in rare cases, patients complain that they feel sick from the first day of using the drug.

Metronidazole is an antibacterial and antiprotozoal drug.

With an overdose of Metronidazole, depressive states, convulsions, leukopenia, neutropenia, photodermatitis, and complaints of feeling sick are possible. When applied intravaginally, a burning sensation, increased urination are possible. Urine during treatment with them may darken due to the release of metabolites.

Removal of Metronidazole by 60-80% is carried out by the kidneys. As a result, severe kidney failure excludes its appointment.

Metronidazole inhibits the formation of a specific enzyme in the human body, the function of which is to break down alcohol. As a result, it is incompatible with the use of alcohol.

The advantages of the drug are its effectiveness for personal use, the presence of a form for intravenous administration, the effect during short treatment courses, bioavailability, easy entry into tissues and cells of the human body, tissue concentrations.

This drug does not kill worms. If it is prescribed, then, as a rule, to combat pathogenic microflora, which can be activated when the physiological balance between normal and conditionally pathogenic flora is disturbed, which can be expected with the invasion of worms. Special preparations are used directly against worms.

A successful combination of Metronidazole with fluoroquinolones. They are similar in basic pharmacokinetic properties. Their combined effectiveness makes it possible to cover a wide range of pathogenic flora. If Metronidazole is active against anaerobic flora, then fluoroquinolones are one of the best in affecting aerobic bacteria. This combination is effective both for pathologies of the abdominal organs and for dentistry.

Metronidazole in suppositories and their price

The reproductive system of a woman is very susceptible to any hypothermia, hormonal disruptions, lack of proper hygiene, promiscuity. Because of these adverse factors, thrush develops, the microflora of the vagina suffers. To restore health, you will need not only the use of tablets, but also topical preparations.

These include various gels, tablets, solutions. The most popular are Metronidazole suppositories, the instructions for use describe in detail for what indications they should be used, the duration of therapy and possible adverse reactions. Patient reviews prove their effectiveness in the fight against fungal and bacterial infections.

Metronidazole is an antimicrobial and antiprotozoal drug, a derivative of the fifth nitroimidazole. The active substance destroys the cells of microorganisms, which leads to their rapid death.

Facultative and aerobic microorganisms are not sensitive to this drug, it will have an effect only with the simultaneous use of antibacterial tablets. Makes the tumor susceptible to radiation, starts the process of regeneration of damaged cells.

S.V. Popov, corresponding member RAMS, Professor E.B. Mazo
RSMU

Introduction

At the International Symposium, held in Monaco in 1954, the term "non-gonococcal urethritis" was adopted, denoting an extensive group of inflammations of the urethra, different in etiology and pathogenesis, except those caused by gonococci. In most cases, non-gonococcal urethritis (NGU) is classified as a sexually transmitted infection (STI), the number of which increases markedly from year to year, taking, according to the report of the WHO Scientific Group, "epidemic" . In 1995, 600-700 million patients suffering from chlamydial urogenital infection were registered in the world , and the economic losses from chlamydial diseases in the US are estimated at 1 billion dollars a year. Early onset of sexual activity, promiscuity, lack of awareness of the rules of contraception, sexual excesses are the reasons for the rapid growth of STIs observed in Russia over the past decade. In 1998, according to the Ministry of Health of the Russian Federation, the number of patients with urogenital chlamydia and trichomoniasis was already 113.8 and 317.2 per 100 thousand of the population, respectively.

There are a large number of classifications of urethritis. Here are some of the most famous in our country. I.I. Ilyin distinguished urethritis of sexual and non-sexual origin . He divided urethritis of sexual origin into venereal and conditionally venereal, and urethritis of non-sexual origin into infectious and non-infectious. O.L. Tiktinsky offers a more extended classification of urethritis:

1. Infectious

A. Non-specific:

1) bacterial

2) viral

3) caused by mycoplasmas

4) ureaplasma

5) caused by chlamydia

6) caused by genital herpes

7) gardnerella

8) mixed

9) mycotic

B. Specific:

1) gonorrheal

2) Trichomonas

3) trichomonas, combined with urogenital infection

2. Non-infectious

1) traumatic

2) allergic

3) caused by the presence of diseases of the urethra

4) exchange

5) congestive

According to the severity of clinical signs, 3 main forms of urethritis are distinguished: acute, torpid and chronic (Porudominsky I.M., 1963).

The mechanism of development of the inflammatory process in the urethra is determined by the state of its mucosa. The antimicrobial resistance of the urethral mucosa depends on its mechanical integrity, the production of a sufficient amount of mucus by secretory epithelial cells and a certain biochemical composition of urethral mucus that has an antimicrobial effect (immunoglobulins, lysozyme, etc.). In case of violation of the integrity of the mucosa, microorganisms are introduced into the zone of its defeat, an inflammatory process develops.

Clinical manifestations of acute urethritis are abundant discharge from the urethra; pain, itching and burning in the urethra, redness and swelling of the lips of its outer opening, pain during urination. The clinical picture of torpid and chronic urethritis is less pronounced and is characterized by discomfort and itching in the urethra, paresthesia in the glans penis. Discharge from the urethra disturbs only in the morning or is absent altogether. However, in the first 2 months the presence of such symptoms is called torpid urethritis, and with a further course - chronic.

Traditional methods of identification Chlamydia trachomatis are its isolation in cell culture, detection of chlamydia antigen by direct immunofluorescence (DIF) with monoclonal antibodies, enzyme immunoassay and polymerase chain reaction (PCR). In this case, the verification of the diagnosis is based on the detection of chlamydia using two methods, one of which is PCR.
laboratory studies necessary for the diagnosis of trichomoniasis include: the study of the native drug, microscopy of the drug, stained with 1% solution of methylene blue or brilliant green and Gram, as well as cultural examination. Moreover, verification of the diagnosis is possible upon detection Trichomonas vaginalis one of these methods. It should be noted the need for simultaneous treatment of sexual partners and the use of barrier methods of contraception during sexual intercourse during therapy in the identification of these pathogens.

Currently, antimicrobial therapy that is effective against chlamydia is carried out with drugs from the groups of macrolides, tetracyclines and fluoroquinolones. Moxifloxacin is one of the antimicrobial drugs from the group of fluoroquinolones successfully used recently in urogenital chlamydia. Nitroimidazoles continue to be the only group of antimicrobial drugs for the etiotropic therapy of trichomoniasis: metronidazole, tinidazole, ornidazole have a selective bactericidal effect against microorganisms whose enzyme systems restore the nitro group. Active reduced forms of drugs disrupt DNA replication and protein synthesis in a microbial cell, and inhibit tissue respiration. Trichomonas remain sensitive to nitroimidazoles, including metronidazole, which remains the drug of choice for the treatment of urogenital trichomoniasis.

Material and methods

In the clinic of urology of the Russian State Medical University, 36 men with urethritis caused by Chlamydia trachomatis and Trichomonas vaginalis. The age of the patients ranged from 19 to 46 years. In 15 (41.7%) patients, only chlamydial infection was found, in 9 (25%) - only trichomonas infection, in 12 (33.3%) - a combination of chlamydial and trichomonas infections was detected. All patients underwent physical examination, digital rectal examination, transabdominal and transrectal ultrasound examination of the prostate gland and laboratory tests (general blood and urine tests, bacteriological examination of urine, microscopic analysis of prostate secretions). The infection was determined in scrapings and smears from the urethra, the identification of pathogens was carried out by polymerase chain reaction (PCR) and direct immunofluorescence (DIF); trichomonads were detected in the study of the native preparation and microscopy of the preparation stained with 1% methylene blue solution.

When clarifying the complaints, it turned out that 21 patients were concerned about the presence of discharge from the urethra, 25 patients had burning, itching and paresthesia of the glans penis, 30 patients had redness and swelling of the lips of the external opening of the urethra, 14 patients had frequent painful urination. As a result of a comprehensive examination, one could assume urethritis in 22 patients, a combination of urethritis and prostatitis in 14 patients.
in all patients, urine culture for the “banal” microflora turned out to be sterile, and in 18 patients, more than 10 leukocytes were found in the secretion of the prostate gland in the field of view. In patients with a picture of the inflammatory process in the prostate gland, ultrasound examination showed echo heterogeneity of the gland with the presence of focal or diffuse hyperechogenicity along with an increase in the volume of the prostate gland (the average volume of the prostate gland was 34.5 cm3).

15 patients with chlamydial urethritis received moxifloxacin 400 mg (1 tablet) once a day, regardless of food intake. 9 patients with trichomonas urethritis received metronidazole 500 mg (2 tablets) every 12 hours with meals. 12 patients with urethritis of mixed etiology took both of the above drugs in similar dosages. The duration of treatment was 10 days.

Along with antimicrobial drugs, patients were prescribed anti-inflammatory therapy (rectal suppositories with diclofenac 100 mg at night), as well as enzyme preparations and vitamins for 10 days. Patients with prostatitis underwent low-intensity transrectal laser therapy. Rectal exposure to laser radiation (ALT "Mustang-2000" apparatus) was carried out in a biomodulated mode, in the red optical range with a wavelength of 0.63 μm, a power of 20 mW. The exposure time was 10 min. The course of laser therapy consisted of ten procedures. All patients were warned about the need to use contraceptives during sexual relations in order to avoid superinfection. Monitoring the effectiveness of therapy using PCR and PIF methods for chlamydial and mixed urethritis, studies of native preparations and microscopic examination of stained preparations (for Trichomonas and mixed urethritis) was carried out 2 weeks after the end of the course of treatment.

results

At the control examination of all 36 patients, carried out two weeks after the end of the course of therapy, Chlamydia trachomatis ceased to be detected in scrapings from the urethra by PIF and PCR in 14 (93.3%) of 15 patients treated for only chlamydial urethritis; Trichomonas vaginalis was not found in the study of native and stained preparations in all 9 (100%) patients with only Trichomonas urethritis, and in the group of patients with mixed infection, both microorganisms were not found after the course of treatment in 10 (83.3%) of 12 men. It should be noted that a patient with a newly discovered PIF 2 weeks after treatment with chlamydial infection was prescribed a ten-day course of an antibiotic from the macrolide group (josamycin 500 mg 2 times a day before meals). At the control examination after 2 months. the pathogen in the scraping from the urethra was not detected by PIF and PCR. In 2 patients with mixed urethritis after a course of treatment with moxifloxacin and metronidazole, a follow-up examination revealed only Chlamydia trachomatis, that is, the infection mixed before the start of therapy passed after treatment into a monoinfectious form. These patients were also prescribed a ten-day course of josamycin, which was sufficient to eliminate the pathogen. At the control examination after 2 months. in all 36 men, chlamydia and trichomonas were not detected.

Taking moxifloxacin and metronidazole led to a significant reduction in symptoms, the disappearance of inflammatory changes in the secretion of the prostate gland in patients with manifestations of prostatitis, and a decrease in the volume of the prostate gland, which was shown by ultrasound data. The dynamics of the above parameters before and after treatment is shown in Tables 1 and 2.

Thus, the therapy of patients with chlamydial and trichomonas urethritis with moxifloxacin and metronidazole led to a significant reduction in symptoms, a decrease from 34.5 to 22.6 cm3 in the average prostate volume and normalization of the number of leukocytes in the secretion of the prostate gland in most patients.

Discussion

The study has demonstrated high sensitivity of chlamydial infection to metronidazole and moxifloxacin , which showed high efficiency in monotherapy of chlamydial urethritis and in complex antimicrobial therapy of chlamydial-trichomonas urethritis in men with a minimum level of side effects throughout the course of treatment. The microbiological efficacy of moxifloxacin in 27 patients with chlamydial and mixed urethritis was 88.8%, the microbiological efficacy of metronidazole therapy in 21 patients with trichomonas and mixed urethritis was 100%. During a short course of antimicrobial therapy, it was possible to achieve effective elimination of the pathogen and a significant reduction in the symptoms of the disease.

Conclusion

Based on the study of the efficacy and safety of moxifloxacin and metronidazole preparations, their high activity against pathogens of urogenital infection (chlamydia and Trichomonas) with a low level of side effects was established. When prescribing drugs for 10 days, it was possible to achieve eradication of the pathogen or the transition of a mixed form of infection into monoinfection. The microbiological efficacy of moxifloxacin and metronidazole was 88.8% and 100%, respectively.

Literature:

1. Ilyin I.I. Non-gonococcal urethritis in men. Moscow. Medicine. 1991. P. 5–9.

2. Kozlova V.I., Pukhner A.F. Viral, chlamydial and mycoplasmal diseases of the genitals. Moscow. Filin. 1997. pp.123–124.

3. Tikhonova L.I. General overview of situations with sexually transmitted infections. "Modern methods of diagnosis, therapy and prevention of STIs and other urogenital infections." Collection of materials of workshops of dermatovenereologists and obstetricians-gynecologists. 1999–2000. S.2–3. 4. Tiktinsky O.L., Mikhailichenko V.V. Andrology. St. Petersburg. Media Press.1999. pp.47–50.

5. Sagalov A.V. Ambulatory polyclinic andrology. Chelyabinsk. Publishing house "Chelyabinsk State Medical Academy". 2002. P.55.

6. Strachunsky L.S., Krechikov V.A. Moxifloxacin is a new generation fluoroquinolone with a wide spectrum of activity. Clinical Microbiology and Antimicrobial Chemotherapy 2001; 3.3:243–258.

7. Practical guide to anti-infective chemotherapy. Edited by L.S. Strachunsky, Yu.B. Belousova, S.N. Kozlov. Moscow. 2002. pp.99–101; 251.

www.medcentre.com.ua

Very often, if a doctor has prescribed metronidazole for chlamydia to treat a patient, then such an appointment may surprise another specialist. This is due to the fact that the instructions for the drug do not indicate the effectiveness of the fight against chlamydia metronidazole. But if you look, it becomes clear that the name of this drug is a synonym for the drugs carnidazole, flunidazole, rosamet, protamet, novonidazole, medazol, camesol, aponitronidazole, protalit, nidosol, zoacid, vagimid, trivazol, tricom, tricocet, trihex, trichazol , metrogil, metronil, gynefvlafir, filmet, phlegyl, entizol, efloran, clone, atrivil, orvagil, klion, ginalgin, flagyl and trichopolum. That is, all these drugs have the same active ingredient, but the commercial names are different. And if you look at the instructions for these drugs, then the appointment of metronidazole for a patient with chlamydia becomes justified.

In addition, it is worth considering the frequency of detection of combined infections of chlamydia with gardnerella and other diseases, the use of this antimicrobial and antiprotozoal drug against which is absolutely justified according to the instructions, and the doctor simply did not tell the patient about the entire viral picture detected, focusing on the main problem.

Often, metronidazole in chlamydia is prescribed in combination with amoxicillin, which allows the two drugs not only to enhance the effect of each other, but also creates conditions under which the development of resistance to metronidazole is suppressed in bacteria. Namely, the rapid adaptation of chlamydia to the treatment used is the main problem in the fight against infection, which dictates the need to use treatment regimens that include drugs from different groups.

It is worth taking into account that taking metronidazole for chlamydia can cause a number of side effects, including constipation, a taste of metal in the mouth, diarrhea, loss of appetite, vomiting, intestinal colic, nausea, pancreatitis, stomatitis, glossitis, incoordination, dizziness, ataxia , depression, insomnia, hyperexcitability, convulsions, hallucinations, headache, rash, fever, thrombophlebitis or leukopenia. If a patient observes any of the listed side effects during the treatment of chlamydia, he should immediately notify his attending physician about this in order to correct the treatment regimen.

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Clinic, diagnosis, treatment

What are the features of the current course of urogenital chlamydia and trichomoniasis?
What is the management of these diseases?

Urogenital chlamydia is one of the serious medical and social problems. This infection has become widespread in various countries of the world, and the number of infected is constantly growing.

Recently, more and more data have appeared on the possibility of the existence of latent or persistent forms of chlamydia both in in vitro modeling and in the patient's body in vivo.

Clinic of urogenital chlamydia

Currently, domestic experts have not come to a consensus on the classification of chlamydia. Some of them use a classification similar to that adopted for gonorrhea, others are arbitrary, in accordance with the localization of lesions or the nature of the infection. It is advisable to use the term "urogenital chlamydia" when making a diagnosis, which makes it possible to identify chlamydia among sexually transmitted diseases.

The clinical picture of diseases of the genitourinary organs caused by chlamydia differs from gonococcal infection mainly by the lower severity of the inflammatory process, the high frequency of complications and resistance to therapy. For women, chlamydia is the most dangerous, because it causes not only a serious pathology of the lower genitourinary system, but is often accompanied by the development of an ascending disseminated infection, the occurrence of pelvic inflammatory diseases, the development of infertility, infection of newborns. Most often and first of all, the cervix is ​​​​infected with chlamydia, from where, as from a reservoir, the process spreads to the urethra, uterus and fallopian tubes, to the internal organs. The incubation period for chlamydia varies between 15-30 days.

A feature of the clinical course of the inflammatory process in chlamydia of the genitourinary organs is an asymptomatic and oligosymptomatic course, multifocality: urethritis, epididymitis, oophoritis, prostatitis, vulvovaginitis, proctitis, colpitis, cervicitis, endocervicitis, salpingitis, parametritis, septic conditions. The acute form of chlamydia with profuse discharge, severe hyperemia of the mucous membranes, with dysuric disorders and severe pain is rare even in men, and in women only in exceptional cases. Subacute and torpid forms are much more common. In men with chlamydia, examination reveals moderate hyperemia and swelling of the sponges of the urethra, sometimes the foreskin of the penis, mucopurulent discharge. In women, chlamydia is manifested by increased pain, pain in the lower abdomen and in the sacrum during and after intercourse, pain during urination. The disease often proceeds without subjective sensations and with minimal clinical manifestations or without them.

The symptomatology of chlamydial diseases in children is more pronounced and, depending on the duration of the inflammatory process, manifests itself in the form of vulvovaginitis, urethritis, cervicitis. Girls get sick more often, especially at an older age, when infection occurs sexually. Along with diffuse hyperemia of the vulva and adjacent areas of the skin, there is swelling of the external genital organs, their maceration as a result of abundant, liquid gray-green discharge. When the urethra is affected, the sponges are hyperemic, edematous, covered with gray discharge, possibly frequent and painful urination.

In pregnant women with chlamydia, complications are more often observed: urgent delivery, premature birth, non-developing pregnancy, spontaneous miscarriage. It is generally accepted that a newborn in 40-50% of cases acquires a chlamydial infection during childbirth due to infection with pathological material when passing through the birth canal of a mother with chlamydia (chlamydia was isolated from newborns from the conjunctiva, nasopharynx, middle ear, trachea, lungs, rectum and vagina), but it is also possible for the infection to enter the amniotic fluid and intrauterine infection of the fetus.

Methods for laboratory diagnosis of urogenital chlamydia

The basic principles for diagnosing chlamydial infection are the same as for other bacterial pathologies. Test procedures include the following:

• Direct visualization of the agent in clinical samples when stained (bacterioscopic method). Bacterioscopic studies involve the identification of the morphological structures of chlamydia in the affected cells (clinical material).
• Determination of specific chlamydial antigens in clinical specimens. Bacterioscopic studies involve the detection of chlamydia antigens in the affected cells (clinical material). In routine laboratory practice, both direct (PIF) and indirect immunofluorescence (NIF) methods can be used. The first method involves the treatment of the drug directly with specific mono- or polyclonal antibodies labeled with fluorescein. When using the second method, the drug is treated first with serum containing unlabeled anti-Chlamydial antibodies, and then with anti-species fluorescent serum.
• Direct isolation from the tissues of the patient (bacteriological method). Bacteriological studies involve the detection of chlamydia in the affected cells (clinical material).
• Serological tests that detect antibodies.

Methods for the serological diagnosis of chlamydia are based on the determination of specific antibodies in the blood serum, as well as in the secrets of persons with or with a history of chlamydia. Interpretation of the results of a serological examination should be carried out in conjunction with an analysis of clinical and epidemiological data, as well as taking into account the characteristics of the serological test used.

For serodiagnosis, enzyme-linked immunosorbent assay (ELISA for the presence of antibodies) is currently most often used. The general principle of ELISA diagnostics is as follows: the antigen is fixed on a solid surface, treated with the test serum, and then with anti-species immunoglobulin associated with the enzyme, which is visualized after the addition of the substrate. The advantage of the method is the ability to automatically record the results and identify classes of antibodies - IgG, IgA, IgM. Given the low immunogenicity of "urogenital strains" of chlamydia and the possibility of the presence of antibodies after a previous chlamydial infection, it is necessary to examine several serum samples in the course of the disease with an interval of 2-3 weeks.

The commonly used method of serodiagnosis is the reaction of indirect immunofluorescence for the detection of antibodies (NIF). When conducting NIF, fixed purified chlamydia antigens are used, applied in the form of dots on glass. The applied serum of patients reacts with antigens of various serotypes, after which it is treated with anti-species luminescent serum. The test is sensitive, in many cases it provides information about the chlamydia serotype; it is advisable to use it in epidemiological studies.

• Determination of specific chlamydial genes in clinical specimens.

Nucleic acid amplification methods

DNA diagnostic methods are based on the complementary interaction of nucleic acids, which makes it possible to identify the nucleotide sequence in the genes of the desired microorganism with high accuracy. Of the numerous modifications of this method, the polymerase chain reaction (PCR) and the ligase chain reaction should be singled out as the most widely used.

Treatment of urogenital chlamydia

Therapy of diseases of the genitourinary tract caused by chlamydia is based on the use of drugs that are active against this microorganism. At the same time, the biological characteristics of chlamydia should also be taken into account. They not only have a high tropism for the epithelial cells of lesions, but also persist in special membrane-limited areas of the epithelium, which is a prerequisite for pathogens to survive the period of drug therapy. This may be associated with failures in treatment, as well as the possibility of the transition of the disease into an asymptomatic and latent state. Therefore, in the course of treatment, not only etiotropic, but also pathogenetic agents are used. All persons who have chlamydia, regardless of the severity of the clinical picture, are subject to treatment, it is also advisable to treat their sexual partners. In all cases, the therapy of this infection, regardless of the technique used, involves the prevention of the development of candidiasis, including the use of nystatin and levorin at a daily dose of 2 million units or nizoral 0.2 g twice a day or pimafucin for 0.2 g twice a day.

Tetracycline drugs, macrolide antibiotics, rifampicin, josamycin, and fluoroquinolones have an etiotropic effect in relation to chlamydial infection. For etiotropic therapy, courses of treatment lasting from 7 to 14 days are used. Uncomplicated infection in men and women should be treated with an antibiotic. With sluggish torpid forms of infection, treatment, as a rule, should be comprehensive. In the treatment of such patients in a hospital, the appointment of an antibiotic should be preceded by immunotherapy and local treatment. On an outpatient basis, in order to prevent the spread of infection, an antibiotic is prescribed simultaneously with immunotherapy (polyoxidonium or cycloferon), followed by local treatment. In the treatment of pregnant women, erythromycin is prescribed 0.5 g orally after meals every 6 hours for 7 days.

The first choice drugs are azithromycin and doxycycline. The high efficacy of doxycycline in chlamydial infection and its low cost retains its priority in the treatment of urogenital chlamydia.

Doxycycline (Vibramycin, Unidox Solutab). For patients with uncomplicated forms of chlamydia, the drug is administered orally: the first dose is 0.2 g, then every 12 hours, 0.1 g. The course of treatment is 7-14 days, in total for the course 1.5-3.0 g. monohydrate) and dosage form (solutab) makes Unidox Solutab the safest drug, and treatment with it has the highest compliance among all known doxycyclines.

Azithromycin (Sumamed). In uncomplicated chlamydia, 1.0 g of the drug is prescribed once. With a sluggish course, the following regimen for taking sumamed is recommended: 1st day 1.0 g once, 2-3 days 0.5 g each, 4-7 days 0.25 g each, total 3.0 g.

Metacycline (Rondomycin). In acute and uncomplicated forms, it is administered orally after meals at a dose of 600 mg (first dose), then 300 mg every 8 hours for 7 days, for a course of treatment of 6.6 g. In other forms, the course of treatment is extended to 10 days.

Clacid (clarithromycin). In uncomplicated forms of chlamydia, 250 mg is prescribed twice a day for 7 days, in chronic - 12-14 days, 400 mg once a day.

Pefloxacin (Abactal). With fresh uncomplicated chlamydia, 600 mg is administered orally once a day for 7 days. In chronic - within 10-12 days.

Lomefloxacin (Maxaquin). With a fresh uncomplicated form of chlamydia, 600 mg is recommended once a day for 7 days, with chronic - for 10-11 days.

Ciprofloxacin (cyprobay, siflox). In uncomplicated and complicated forms of chlamydia, it is prescribed orally for 10 days, the first dose is 500 mg, followed by 250 mg after 12 hours; for a course of 5.0 g.

Josamycin (Vilprafen). In uncomplicated chlamydia, 500 mg every 12 hours are administered orally for 7 days; for a course of 7.0 g.

Treatment of children is carried out with the same drugs, taking into account contraindications, in doses determined in accordance with age; local procedures are more often used: sitz baths from infusion of chamomile or sage flowers (one tablespoon per one glass of boiling water), or potassium permanganate solution twice a day, or douching with the same infusions and solutions, as well as general strengthening treatment.

In patients with urogenital chlamydia, especially with its prolonged, recurrent course, repeated or irrational use of antimicrobials, violations of the intestinal microbiocenosis are detected, which in turn negatively affects the course of physiological processes and the reactivity of the body.

The diagnosis of intestinal dysbacteriosis is based on the results of bacteriological studies of feces in conjunction with clinical manifestations, after which drug correction of dysbacteriosis is carried out.

Trichomoniasis

Urogenital trichomoniasis is a widespread sexually transmitted infectious inflammatory disease caused by the protozoan Trichomonas vaginalis.

Urogenital Trichomonas come in three forms: pear-shaped, amoeboid and budding; the latter is less common than the others. The pear-shaped form is considered the main one, and the rest are intermediate stages of the life cycle of Trichomonas, which are unstable outside the human body. A prerequisite for their viability is the presence of moisture; when dried, they quickly die. These protozoa are also unstable to many other environmental factors: an increase in temperature over 40 ° C, direct sunlight, changes in osmotic pressure, exposure to antiseptics, etc.

Genitourinary trichomoniasis is a multifocal disease in which urogenital Trichomonas can be localized in all urinary organs.

Urogenital Trichomonas, caught on the mucous membrane of the urethra during intercourse, are kept in the first 12-24 hours on the surface of the navicular fossa lined with squamous epithelium. Reproducing, they spread like ivy over the surface, but do not penetrate into the cracks of the squamous epithelium. In response to an invading infection, active hyperemia appears, which is expressed in swelling and redness of the lips of the external opening of the urethra, and subjectively the patient feels itching and slight tickling. As urogenital Trichomonas multiply and spread along the mucous membrane of the urethra, they reach places lined with columnar epithelium in about 24-36 hours. With the involvement of the columnar epithelium in the inflammatory process, serous fluid seeps through the vessel walls, which loosens the connection between epithelial cells and connective tissue . The normal state of the vascular walls is disturbed, an abundant migration of leukocytes begins with their infiltration of the upper layers of the subepithelial tissue.

Under the influence of urogenital Trichomonas, the epithelium of the urethra is injured, degenerates; the mutual connection between the cells and their nutrition are disrupted, the epithelium is exfoliated up to the formation of erosions and ulcers. The latter arise due to the action of protozoan proteolytic enzymes on epithelial cells and subepithelial tissue. The mucous membrane of the urethra swells, thickens, loses its elasticity, bleeds easily.

The cavities of the glands and excretory ducts are filled with leukocytes and multiplying urogenital Trichomonas.

In the absence of treatment, after 3-4 weeks, the inflammation begins to subside, the discharge stops or is observed only in the morning, after heavy drinking or sexual intercourse. Metaplasia of the epithelial cover of the urethral mucosa occurs: instead of a degenerated squamous cylindrical epithelium, a stratified squamous epithelium is formed.

Clinic

The clinical course of trichomoniasis does not differ from that in inflammatory diseases of the urogenital organs of another etiology and often resembles gonorrhea.

There is no consensus on the duration of the incubation period for trichomoniasis. In the literature available to us, different data are given: from 3 days to 3-4 weeks and even 55 days.

Of great practical importance is the question of the classification of trichomoniasis. In order to prescribe the correct treatment, the classification, as in gonorrhea, is based on the intensity of the body's reaction to the introduction of urogenital Trichomonas, which is reflected in the clinical manifestation of the disease. From this point of view, it is advisable to distinguish the following forms of trichomoniasis.

• Fresh trichomoniasis: a) acute; b) subacute; c) torpid;
• Chronic;
• Trichomonas carrier.

Fresh forms of trichomoniasis should include cases with a disease duration of up to 2 months with severe and moderately pronounced inflammatory processes of the human genitourinary sphere. Chronic forms of trichomoniasis include sluggish cases of the disease (more than 2 months or if the timing of the onset of the disease is unknown). Trichomonas carriage should include cases when there are no inflammatory reactions in the body, but during sexual intimacy, urogenital Trichomonas are transmitted to healthy individuals, causing them to have a typical clinical picture of the disease.

Trichomoniasis should also be classified according to the localization of inflammation.

The main lesions in urogenital trichomoniasis are the urethra in men, the vagina and urethra in women. In women, large vestibular and paraurethral glands, the cervix may be involved in the inflammatory process. Trichomonas are found in the uterine cavity, in saktosalpinks, ovarian cysts. There are reports of a connection between urogenital trichomoniasis and pregnancy complications (premature birth, early rupture of the membranes, etc.). The clinical picture of uncomplicated urogenital trichomoniasis in women is characterized by the presence of an inflammatory process in the vagina and the vaginal part of the cervix. In the future, vestibulitis, paraurethritis, endocervicitis, endometritis, etc. may join, which is considered as a complicated course of the disease.

In men, Trichomonas can cause damage to the prostate gland, seminal vesicles, epididymis, cooper glands.

An ascending infection of the urinary tract and kidneys (cystitis, pyelitis, pyelonephritis) may develop. Complications in trichomonas urethritis in men are more common than in gonorrhea. The clinical picture of trichomonas prostatitis, vesiculitis, epididymitis differs from that of gonorrheal etiology, which usually proceeds more rapidly. With a prolonged course, the formation of single or multiple strictures of the urethra is possible. In girls, urogenital trichomoniasis occurs with damage to the vulva and vagina.

Laboratory diagnostics

The diagnosis of urogenital trichomoniasis is established with mandatory detection T.vaginalis through laboratory testing. For laboratory diagnosis of trichomoniasis, scopic methods and cultural studies are used. Due to the common ways of infection, urogenital trichomoniasis is often combined with other sexually transmitted diseases, and therefore patients should be subjected to appropriate examination. In the case of concomitant urogenital infections (associations), their treatment is carried out simultaneously.

The most widely used, but not sensitive enough method in the laboratory diagnosis of trichomoniasis is the microscopic examination of native or stained preparations. When examining a native preparation, the pathological material is placed in a drop of warm isotonic sodium chloride solution on a glass slide, thoroughly mixed, covered with a cover slip and immediately examined in a microscope with a 40 objective. The best results are obtained by viewing the native preparation in a microscope with a dark-field condenser, since In this case, single and weakly mobile individuals are found in clusters of cellular elements due to the clearly visible movement of the flagella. In the native preparation, Trichomonas are characterized by an oval or round shape, the presence of flagella and jerky movements of the protozoa.

In the study of native drugs, one should be aware of the possibility of finding flagellated protozoa of the Bodonid family in the urine. Unlike Trichomonas, they are smaller and have only two flagella, which leads to their rapid forward movement in a straight line. The presence of leukocytes in the preparation in combination with a large number of well-moving rods attached to them can also lead to errors in the recognition of Trichomonas.

In order to detect Trichomonas vaginalis in stained preparations, numerous staining methods are used, in particular, methylene blue, gentian violet, according to the methods of Gram, Romanovsky-Giemsa, Leishman-Romanovsky, etc. The widespread use of methylene blue is due to the fact that it is also used for staining smears on gonococcus. The study of stained smears allows you to determine the morphology of the pathogen, smears do not require immediate examination, which is especially important during a mass examination for trichomoniasis. However, diagnostic errors are possible, since epithelial cells can be mistaken for Trichomonas.

The cultural method for diagnosing trichomoniasis is more reliable and sensitive than microscopic examination. To a greater extent, its effectiveness depends on the quality of the nutrient media used. The proposed media with high growth properties include meat-peptone broth (MPB), liver preparations, mineral salts, sugars, human or animal blood serum, hydrochloric acid cysteine ​​and other ingredients.

Treatment

Genitourinary trichomoniasis often occurs as a mixed protozoal-bacterial disease with involvement in the inflammatory process of many organs of the urinary tract. In view of this, in the treatment of this disease, it is advisable to use complex therapy. In addition to protistocidal drugs, antibiotics, immunotherapy, vitamin therapy, biogenic stimulants, etc. are also widely used. Local treatment is also widely used: washing and instillations of the urethra, baths and wiping the vagina in women, etc. less than two menstrual cycles. If the source of trichomoniasis disease is unknown, dynamic medical observation of persons with urogenital trichomoniasis is performed within 6 months with monthly blood tests for classic serological reactions. This period is necessary for the prevention and timely detection of syphilis due to the fact that the drugs used in the treatment of trichomoniasis also have a treponemocidal effect.

The main drugs for the treatment of trichomoniasis are:

Metronidazole (trichopolum, flagyl, klion). It has a pronounced effect on urogenital Trichomonas. An important feature of this tool is its activity when taken orally; the drug is rapidly absorbed and accumulates in the blood at concentrations that are detrimental to Trichomonas. Metronidazole is widely used to treat acute and chronic trichomoniasis in men and women. The drug is available in tablets of 0.25 and 0.5 g and in the form of vaginal suppositories and tablets of 0.5 g.

The first scheme of taking the drug: on the 1st day, 2 tablets (0.5 g) three times a day with an interval of 8 hours. Then the daily dose is reduced daily by 1 tablet with the same interval. The total dose per course is 3.75 g for 6 days. According to the second scheme, 0.25 g is prescribed twice a day with an interval of 12 hours; this scheme provides for the additional administration of 1 vaginal suppository or tablet containing 0.5 g of metronidazole. The drug is used for 10 days inside and topically. If necessary, the course of treatment is repeated in a month.

Tinidazole (fasigin, triconidazole, etc.). It is similar in structure and action to metronidazole. Assign inside in tablets of 0.5 g. Tinidazole regimen: 1) once at a dose of 2 g (4 tablets); 2) 0.5 g every 15 minutes for 1 hour. Contraindications are the same as for metronidazole: the 1st trimester of pregnancy and the period of breastfeeding, hematopoiesis, active diseases of the central nervous system. During treatment, you can not take alcoholic beverages. Blood tests should be done before and during treatment.

Clindamycin- 300 mg orally twice a day.

Solkotrykhovak- 0.5 ml intramuscularly, three injections with an interval of 2 weeks, then a year later 0.5 ml once.

To establish the criteria for the cure of urogenital trichomoniasis, they begin 7-10 days after the completion of treatment using microscopic and cultural methods of examination.

local treatment. With fresh, uncomplicated trichomonas lesions, there is no need for local treatment, since general treatment is sufficient to eliminate inflammation. With torpid flowing fresh inflammatory processes and chronic forms of trichomoniasis, local treatment is prescribed.

Topical drugs are used simultaneously with general protistocidal drugs.

Metronidazole- vaginal balls (tablets) of 0.5 g are prescribed intravaginally once a day for 6 days.

Ornidazole- vaginal tablets of 0.5 g are inserted into the vagina once for 3-6 days.

Ginalgin- 1 tablet intravaginally for 10 days.

Clindamycin- 2% vaginal cream applied daily for 4 consecutive days.

Klion D (metronidazole)- vaginal tablets of 0.1 for 5 days.

Atrican (tenonitrozole)- 250 mg twice a day for 4 days.

For local treatment, instillations of the urethra with a 0.25-0.5% solution of silver nitrate are also used every other day with a 2% solution of protargol or a 1% solution of collargol.

Treatment of pregnant women. Treatment is with metronidazole (excluding the 1st trimester of pregnancy) at a dose of 2.0 g orally once.

Treatment of children. Metronidazole is prescribed to children aged 1 to 5 years orally, 1/3 tablet containing 250 mg, two to three times a day; 6-10 years - 0.125 g twice a day; 11-15 years - 0.25 g twice a day for 7 days.

Note!

www.lvrach.ru

Characteristics of diseases

Trichomoniasis is a very common acute infectious disease. The main way of infection with them is unprotected sexual intercourse (traditional sex) with the carrier of the infection. As for the transmission of the disease through oral or anal sex, this is unlikely.

Important! Trichomoniasis is genital infection. For this reason, they cannot be infected through shaking hands, sharing utensils or kissing.

Despite this, there is a small risk of transmission of the disease when using someone else's underwear, using a wet washcloth, towels and visiting the bath. This is justified by the fact that Trichomonas is able to actively live in a humid environment for several more hours.

In the event that the infection with this disease occurred in a domestic way, then, as a rule, a person does not even know about it and finds out during a routine diagnosis. In most cases, then the infection has already acquired a chronic form.

After the penetration of Trichomonas into the human body, the incubation period begins. It lasts for 2-3 weeks. At this time, pathogenic bacteria adapt to a new habitat, after which they begin to actively make themselves felt.

During the incubation period of the bacterium, the patient does not feel any signs of the disease.

As for chlamydia, it is also infectious sexually transmitted disease. It is characteristic that the causative agents of this infection - chlamydia, can affect not only the genitals (vagina, cervix), but also the rectum, urethra in men and eyes.

Carefully! Chlamydia is considered an extremely common disease.

According to studies, it is observed in 10% of people under thirty who are sexually active.

Most susceptible to this infection are those people who often change sexual partners and practice sex without barrier contraception (condom).

You should know that the most common chlamydia infection occurs during intimate intercourse (traditional or anal, it does not make much difference, since the probability of transmission of the infection is equally high in both cases).

In addition, chlamydia can also be transmitted from mother to newborn child through sexual contact. In this condition, the baby has a high risk of developing pneumonia and eye diseases.

The household route of transmission of such an infection is not excluded, but it is unlikely. This is justified by the fact that these pathogenic bacteria die very quickly when they are outside the human body.

Moreover, for a full-fledged infection, it is necessary that a large number of active chlamydia penetrate the body. Otherwise, infection will not occur.

After chlamydia enters the body, the incubation period begins. It may take one to three weeks for the first symptoms to develop.

Symptoms of trichomoniasis

Manifestations and general symptoms of trichomoniasis are not much different from traditional pathologies of the genitourinary system. Moreover, very often this infection is confused with gonorrhea, since the signs of these pathologies are also quite similar.

Reference! A very important role in the features of the manifestation of trichomoniasis is played by the form of its course. Thus, a person can have an acute infection, a chronic infection, and a condition such as a carrier state, when a man or woman does not get sick themselves, but can infect other people.

The acute type of infection is manifested by pronounced symptoms.

Women may experience the following symptoms:

In men, the acute form of this disease can provoke the following symptoms:

• Weakness and pain when urinating.
• Decreased sex drive and prostate problems.
• Burning during intimate intercourse.
• The appearance of unpleasant discharge from the urethra, which most often occurs in the morning.
• Fever and fever occurs with a weakened immune system, when infections are very easy to infect the body.

In the chronic form of the course, trichomoniasis has the same symptoms as in the acute one, but they are mild and the person may not even pay attention to them.

As a rule, the chronic form of such a disease is detected already when it began to cause dangerous complications. That is why infectious disease specialists strongly recommend regularly taking a preventive test for trichomoniasis, even if a person, at first glance, is not bothered by any signs of pathology.

In the event that a person is only a carrier of such a disease, then the least harm is done to his body. Thanks to a strong immune system, he will not suffer from the consequences of trichomoniasis, however, in the event of a sharp decrease in immunity, the disease can again become acute.

Symptoms and signs of chlamydia

Chlamydia (trichomoniasis, its symptoms are very similar to this disease) is characterized by a sluggish course, so most patients learn that they are infected by accident.

This infection can occur in acute and chronic forms, each of which has its own symptoms.

During an acute course, men may develop the following signs of the disease:

• Hyperemia of the urethra and its severe inflammation.
• Swelling of the head of the penis.
• The appearance of unpleasant mucous or purulent discharge from the urethra.
• Pain when urinating.
• General deterioration of health and fever.
• Weakness.

Attention! In advanced form, chronic chlamydia in men will not cause acute symptoms, but it can provoke the development of prostatitis, proctitis and urethritis.

In women, acute chlamydia usually presents with the following symptoms:

• Discomfort during intercourse and pain during urination.
• Inflammation of the genitals.
• Drawing pain in lower abdomen.
• The appearance of vaginal discharge, which has a specific character.

Carefully! Untreated chlamydia, both in men and women, can cause a very dangerous complication in the form of infertility.

That is why it is important to respond to its manifestations in time and treat this disease.

It should also be noted that sometimes such an infection for a long time may not manifest itself at all, that is, proceed without symptoms. For this reason, every six months, both sexual partners need to take a preventive analysis.

Chlamydia treatment

Treatment when chlamydia is detected largely depends on the form of the disease, its neglect, symptoms and the presence of concomitant pathologies in a person. Thus, therapy is selected for each patient individually.

Treatment of chlamydia is aimed at suppressing the activity of chlamydia and preventing the development of dangerous complications.

At the same time, it is worth remembering that chlamydia themselves are highly resistant to many drugs, so the doctor must supervise the therapy and replace the medicine with another if it is not effective enough.

To eliminate chlamydia, you can use the following drugs:

1. Medicines Doxycycline and Azithromycin. They are most often used to treat chlamydia. Usually, they are prescribed in combination and used for several weeks.
2. Macrolide antibiotics (Rifampicin) are considered very effective. The duration of their intake in acute infections should be at least two weeks. In the case of a chronic disease, a person needs to take such drugs in courses.
3. For general support of the body, the patient must be prescribed immunomodulatory drugs.
4. Additional drugs that can be prescribed for chlamydia are: Kladitz, Metaklin, Lomefloxacin. Dosage and method of administration is selected separately for each patient.

It is impossible to self-medicate the disease.

Important! The second sexual partner is also recommended to be tested for chlamydia and, if necessary, treated.

Treatment of trichomoniasis

The following drugs are commonly used to treat trichomoniasis:

The regimen for taking these drugs and the duration of treatment is selected individually for each patient.

Also, as a supplement, local and symptomatic therapy can be carried out.

chlamydia,

Treatment with Dazolik

In pediatrics, Tiberal is used for the same diseases as in adults: for amoebiasis, giardiasis, trichomoniasis, gardnerellosis, etc.

First signs

At trichomoniasis conservative therapy should be carried out simultaneously with both sexual partners, since trichomonas vaginalis transmitted through sexual contact.

Symptoms of increased concentration of active components in the blood serum:

Overdose

Instructions for use Dazolik

compatible with ethanol.

Laboratory techniques used to detect chlamydia:

List of candles for women

Vaginal suppositories are inserted deep into the vaginal cavity. It is recommended to administer 1 suppository twice a day. The course of treatment is designed for 7-21 days, depending on the patient's condition and the course of therapy.

Candles of this type can be used both rectally and vaginally.

The drug is contraindicated for use during periods lactation and pregnancy . especially in the first trimester, as it can irreversibly affect the vital systems and organs of a developing child.

Synonyms

isopropyl alcohol;

Dazolik is antibiotic antiprotozoal nature, that is, the main pharmaceutical action of the drug is aimed at the destruction of microorganisms that belong to the simplest. In particular, the active components of the drug disrupt the chain structure deoxyribonucleic acid . the main carrier of genetic information necessary for normal life and reproduction in living cells. Antibiotic properties are effective against a wide range of microorganisms, which include:

You can buy such drugs without a prescription at any pharmacy, but it is better to first consult with a gynecologist.

Firstly, suppositories are used first, which actively destroy viruses and bacteria, inhibiting the spread of chlamydia. These include Hexicon" and "Genferon".

Since an excessive load is placed on the liver, hepatoprotectors are prescribed (Karsil, Phosphogliv, Essentiale Forte), to protect the intestinal microflora, it is necessary to take probiotics (Bifidumbacterin, Linex, Laktobaterin, Bifiform).

There is no specific antidote. Treatment is only symptomatic, diazepam is prescribed for severe convulsions, and antihistamines for skin reactions. Patients are also advised to take sedatives.

immunofluorescence reaction. The material taken from the urethra is stained with a special substance and examined under a special microscope (fluorescent). If chlamydia are present, they glow in the microscope lens, like fireflies;

genitals

After waiting one month, after taking the antibiotic, I checked for infection - NO INFECTION ... I am CLEAN .. like a child J.

In newborns, chlamydial infection manifests itself in the form of diseases such as pneumonia, vulvovaginitis, proctitis, bronchitis, tubootitis, conjunctivitis. About 70% of cases, the infection is generalized, which contributes to the infection of different organs. But according to statistics, conjunctivitis is most often diagnosed.

Ways of transmission of chlamydia

At trichomoniasis use a dose of 500 mg twice a day (two tablets for 24 hours) for 5 days. In pediatric practice, the amount of a pharmaceutical preparation is calculated based on body weight - 25 mg / kg and tablets are taken only once a day.

During the course of drug therapy with Dazolik, the following undesirable consequences may occur:

Dazolik can be used to treat children only as directed by a doctor. The duration of the course of taking the drug and the dosage is determined individually depending on the age, weight and diagnosis of the child.

Treatment with Tiberal

In accordance with the asymptomatic nature of the disease and the general prevalence, chlamydia during pregnancy is diagnosed very often. Usually, urogenital chlamydia is considered traditional and is characterized by the absence of symptoms. Almost its only manifestation is a disease such as cervicitis or pseudo-erosion of the cervix (in which the cervix itself becomes inflamed).

If you ignore the symptoms at this stage, the disease flows into a chronic form. Sometimes chlamydia occurs without external symptoms, but progresses latently. Chronic chlamydia leads to erectile dysfunction and infertility.

Traditional medicine for chlamydia is powerless, and self-medication only harms the patient and worsens the state of health.

• Ecomed

The following bacteria can be noted, which are destroyed by Hexicon candles:

Pharmacodynamics and pharmacokinetics

In many patient reviews, there is a mention of the treatment of chlamydia with Tiberal and the lack of effect in this treatment.



Itut began for me ... going through the torments.

Chlamydia: symptoms in children

• Klabaks
• trichomoniasis;

Tiberal and alcohol

Dazolik price, where to buy

Together with suppositories, it will be useful for the reader to know how Azithromycin is used for chlamydia. and what is the drug treatment regimen.

• extraintestinal forms of amebiasis - for children over 12 years old, 1 tablet, 7-12 years old - 375 mg each, 1-6 years old - 250 mg each, younger than a year old - 125 mg 1 r. / day, for 5-10 days (exact the duration of the appointment is determined by the doctor);
• sodium lauryl sulfate ;

It is also worth noting that it is not easy to achieve an excessive plasma concentration of active ingredients in the blood plasma, because Dazolik has a wide range of applications, which cannot but give an extra point over other antiprotozoal antibiotics.

Morning stricture.

Dazolik greatly enhances the therapeutic effects coumarin anticoagulants . which may appear as pinpoint hemorrhages . hemorrhagic rash or purpura .

It is undesirable to prescribe Tiberal to patients suffering from chronic alcoholism and people with impaired liver function.

The main route of transmission of chlamydia is sexual contact with an infected partner (and there may be no symptoms of the disease). The infection is transmitted through any kind of sexual contact, with vaginal secretions and contaminated semen.

• Protosal.



Dazolik is rarely used to treat pregnant women (especially in the first trimester of pregnancy) and women during lactation. This is explained by the fact that the active component of the drug can penetrate the placental barrier and enter the mother's milk.

• Pathogenic fungi, primarily thrush,

It is worth noting that the symptoms of chlamydia in men, just like in women, are absent or slightly expressed. The manifestation of symptoms, if observed, is at the onset of the disease, and in most cases this manifests itself in the form of one or another inflammation of the urethra, which has a chronic form of the course, the duration of which is about 2 months. But be that as it may, there are no special symptoms that would indicate that the cause of a certain ailment is the effect of chlamydia on the body of men.

I burned the entire urethra, the white discharge was replaced by dull rusty ..thick ... to urinate, you had to howl at the same time in pain. Guys...it's SUCH a pain....this is the second birth, probably...only for a man.

Depending on the manufacturer, the price of a Tiberal package with one blister ranges from 477 to 750 rubles.

Until now, there is no accurate and universal remedy for the treatment of chlamydia, as well as there is no single developed treatment regimen.

Biconvex tablets of a round form of white or close to white color. Each piece is covered with a shell and has a characteristic risk on one of the sides. Tablets are placed in aluminum foil or PVC blisters of 10 pieces each. The carton contains 1 or 5 blister plates.

• ultraviolet - direct sunlight is detrimental to chlamydia, as well as to most pathogenic microorganisms

Forum on venereology / Treatment of chlamydia. stages and results.

• hypersensitivity . acquired or hereditary intolerance, idiosyncrasy in relation to the constituent components of the drug;

Total posts: 251

• watery, purulent discharge with mucus from the urethra



"Viferon"

• starch;

Persons whose job is to drive vehicles or other mechanisms are not recommended to use the drug, because. it can cause drowsiness, dizziness, convulsions and general weakness.

• magnesium stearate;

In most cases, chlamydia manifests itself in the form of ophthalmic chlamydia (conjunctivitis). At birth from a mother with chlamydia, it is diagnosed in 30-50% of cases, by a period of 3-15 days.

Interestingly, the use of candles "Viferon" leads to the fact that in the human body begins increased production

The very process of pregnancy with chlamydia is always due to the occurrence of many complications of an obstetric scale, which poses a threat of termination of pregnancy, ectopic pregnancy or spontaneous abortion (especially true for the initial period), as well as late toxicosis and polyhydramnios.

The dose and duration of treatment depend on the diagnosis and are prescribed only by a doctor.

• Both partners are being treated

Tiberal during pregnancy and lactation

• trichomoniasis - 25 mg per kilogram of body weight, once;

Application instruction of Tiberal

The appearance of one of the symptoms of chlamydia is a reason for contacting a urologist.

Concomitant medications: treatment regimen for chlamydia

There is no specific antidote for the drug Dazolik in pharmaceutical practice, therefore, in case of an overdose of the active ingredients, it is used symptomatic treatment . So, for example, to stop convulsive seizures, it is used Diazepam . sedative pharmaceutical preparation of the central type of action. belonging to benzodiazepine series tranquilizers .

Release form

Tsiprolet

Dazolik's analogs

Ornidazole increases the duration of the muscle relaxant action Vecuronium Bromide .

Chlamydia: symptoms in women

In chronic recurrent chlamydia, there is a need to prescribe immunomodulators. In the treatment of sexually transmitted infections, agents that stimulate the body's defenses play a key role. The drugs are administered intramuscularly during the course of antibiotic therapy.

The World Health Organization is not in vain pursuing a policy of protected sex among adolescents. Cases of urogenital chlamydia are increasingly recorded among young people from 14 to 18 years. Most diagnoses occur between the ages of 20 and 40.

children

Like any drug, Tiberal has both positive and negative patient reviews. In positive reviews, patients and attending physicians note a high therapeutic efficacy, which eliminates the need to prescribe a second course of treatment.

PID (pelvic inflammatory disease) in women.

linked immunosorbent assay. Determination of antibodies (IgM, IgA, IgG) to chlamydia in the blood. These antibodies are produced by the body itself as a defense against infection. Antibodies to chlamydia are detected during interaction with special preparations that contain chlamydial antigens, which together with antibodies create a strong complex that can be detected in various ways. In addition to simple scrapings, blood is also taken to perform the analysis by this method;

How to take Dazolik?

For the treatment of amebiasis, two schemes can be used, differing in the duration of the course and doses.

Natamycin

Ornidazol-Vero (Russia);

An individual dosage is prescribed if the disease has become chronic. Here, the duration of treatment can take up to 3 months.

Immediately the question is where and how to treat it if you do not work and there is no way to waste money. I called about 15 Moscow clinics. Treatment of chlamydia from 5-15 thousand rubles, in time from a week to a month (at least urologists and venereologists claimed so). There is no money. I don't know what to take. Here the only assistant is my INTERNET, all hope is on it. At the request "ask a question to a urologist or venereologist", my Internet gave me many sites where you can ask a doctor a question online. Guys… what a mess this is. Look, not one of the doctors answered you specifically ... what can be treated and how, referring to delusional medical ethics and a bunch of other reasons that are just as illegible. People with a problem turn to doctors online, asking for help, and what in response. Come to the reception ... we won’t say in absentia ... medical ethics.

With giardiasis, Tiberal is prescribed in a short course: 1-2 days.

It is characterized by a triad of symptoms: conjunctivitis, urethritis and arthritis. Also, with the syndrome, circinal balanoposthitis and skin lesions can occur.

Instructions for using candles

Clarithromycin

In addition, they can be used during pregnancy and while breastfeeding, that is, they have practically no restrictions and contraindications.

amoebic dysentery - 4 tablets each with a body weight above 60 kg; 3 tablets, if body weight is above 36 kg; 40 mg per kilogram of body weight with a body weight of less than 36 kg, 1 p./day, for 3 days;

Prostatitis

Drug Interactions Dazolik

The choice of interferon preparations, immunomodulators, probiotics, hepateroprotectors, antioxidants, enzymes and treatment of chlamydia are presented in the tables.

How to take Tiberal?

Ornisid Forte;

Rehabilitation. The recovery period takes about two weeks. Here, drugs are prescribed to restore liver function, probiotics, and sometimes physiotherapy.

Clostridium perfringens (clostridium perfringens );

Dosage of Tiberal

tremor (trembling of the limbs);

For children whose weight does not reach 35 kg, the daily dose is 25 mg / kg and is divided into 2 doses.

convulsions resembling an attack of epilepsy.

How to treat chlamydia in men: antibiotics, the mechanism of development and symptoms of the disease

I immediately in KVD. They took all the tests in full, but the next day they said that they didn’t find anything ... I’m shocked. I went to another KVD, they didn’t find me there either, but they explained ... that they take everything except chlamydia. Then I went to the Research Institute of Epidemiology (CMD), where I was tested for all infections, where I was successfully diagnosed with chlamydia.

In children with chlamydial pneumonia, often the Apgar score is less than six points. The early neonatal period in almost every infected person is always accompanied by a manifestation of a syndrome of respiratory disorders of a certain severity, and about 30% of cases cannot do without mechanical ventilation.

Weight over 35 kg - 40 mg / kg.

"Hexicon" - based on chlorhexidine. These suppositories do an excellent job with gram-negative and gram-positive microorganisms.

To prevent the development of candidiasis, due to prolonged exposure to powerful antibacterial components, antimycotic drugs are prescribed:

Often the presence of chlamydia causes premature termination of pregnancy; the danger is infection of the fetus during childbirth (according to statistics - 40% of all cases).

Giardiasis are treated according to the following scheme - for the adult age category and in pediatric practice, patients weighing 35 kg or more - 1.5 g twice a day. If the patient's weight is less than 35 kg, then, as in the treatment of dysenteric amoeba, the dosage of the drug is 40 mg / kg once a day. The duration of treatment is 1-2 days.

The package contains a blister with 10 tablets.

Chlamydia in pregnant women: symptoms and features

disinfectants - microorganisms react to household chemicals, so any sanitation agent will destroy them on household items

In most cases, patients speak well of Dazolik: they note its high therapeutic efficacy and a quick recovery when using it. The authors of many reviews note the good tolerability of the drug, but there are also reviews of some side effects of this drug (often mild).

peripheral sensory neuropathy (unpleasant, painful sensations in the lower extremities).

purified talc;

Complications and consequences of self-treatment

Help phagocytes and leukocytes in the fight against chlamydia.

A disease leading to narrowing of the prostate ducts, death of the glandular tissue of the prostate gland, changes in the quality and quantity of prostate secretion, which in turn leads to rapid death and dehydration of spermatozoa.

The antibiotic drug is excreted predominantly by the kidneys - about 60-70 percent of all metabolic products. 20-25 percent is excreted through feces. 5 percent of the dose taken is found unchanged in the urine and feces.

a consequence of a viral or bacterial infection

Dazolik is produced by the Indian company Sun Pharmaceutical Industries Ltd and can be used to treat adults and children from the neonatal period.

Analogues (synonyms) of Dazolic containing the same active ingredient ornidazole are:

Tiberal (Switzerland);

ureaplasma,

In the case of infection of the rectum as a result of non-traditional sexual contact, pain, burning and discharge occur in the anus. If chlamydia gets on the mucous membrane of the eyes, chlamydial conjunctivitis may develop: redness of the proteins, swelling, purulent discharge.

Ornidazole;

As a result, after listening to me more specifically, the doctor said that the drug was enough for me.

giardiasis - 3 tablets with a body weight of more than 36 kg, 40 mg per kilogram of body weight with a weight of less than 36 kg, 1 p. / day, for 1-2 days.

Tiberal for amoebiasis

The drug is available only in the form of cylindrical white tablets odorless, coated. Each tablet contains 500 mg of ornidazole and auxiliary components.

Hemomycin

Interaction of Tiberal with other drugs

Gairo (India);

culture for chlamydia with antibiotic susceptibility testing. This is the most time-consuming and expensive method, the results of the analyzes can be obtained in a few days. If the result is positive, then you definitely have chlamydia. Also analyzes show, from what antibiotic your infection dies;

Many from birth or on the first day after birth, hepatosplenomegaly is detected, in about 50% of cases edematous syndrome is diagnosed. Compared with the course of the disease in older children, during this period, chlamydia infection is accompanied by severe toxicosis. At the same time, its maximum manifestation is diagnosed at 5-7 days of life, which is accompanied by pale skin and the formation of marble patterns on it, as well as regurgitation, bloating and disorders of the nervous system. In half of the cases, an early form of lymphadenopathy is diagnosed, and in more rare cases, a rash (short-term or punctate). By 2-3 weeks of the disease, against the background of sputum discharge, a paroxysmal cough is added.

enhance the effectiveness of coumarin anticoagulants;

The cost of Dazolic is estimated by most patients as "affordable".

Giardia lamblia (intestinal giardia );

humidity level - in conditions of high humidity, chlamydia are perfectly preserved, so they can live up to 5 days in towels, dishes, toilet lids.

Tiberal for chlamydia

Shelf life

acetone;

Tiberal for children

Reiter's syndrome. Simultaneous damage to the skin, joints and mucous membranes of the eyes.

We note right away that suppositories for chlamydia can be shown not only to women, but also to men.

Each tablet as constituent components contains:

Itraconazole

Ornisid forte (Turkey).

Antibiotic pulse therapy gives a good effect: a week of treatment, a week break, only 3 cycles. Today, drugs based on doxycycline are considered the best antibiotic for chlamydia.

Chronic chlamydia cannot be cured without the appointment of immunomodulating agents against the background of antibiotic therapy.

The course of such treatment should last from 5 to 10 days, the exact framework is set by the attending physician, depending on individual indicators during conservative therapy.

Meradazole;

Alcohol and ethanol metabolism products are compatible with the pharmaceutical product, its constituents do not inhibit acetaldehyderogenase and do not contribute to the accumulation of toxic substances, therefore there is no disulfiram-like reactions . however, the use of alcoholic beverages during the course of conservative treatment, as well as in combination with other antibiotics, is not recommended.

For the prevention of anaerobic infections, the drug is prescribed 1-2 tablets (0.5-1 g) before surgery, and 1 tablet (0.5 g) 2 times a day for 3-5 days after surgery.

In the treatment of all other forms of amebiasis, the duration of the treatment course increases to 5-10 days.

The drug is absorbed by the body by 90%, reaching a maximum concentration in the blood within 3 hours after ingestion. The active substance perfectly penetrates into all liquid media of the body, including cerebrospinal fluid. With a single application, 85% of Tiberal is excreted from the body after 5 days.

If amoebiasis extraintestinal . then the drug is taken 2 times a day, morning and evening, and the dosage depends on age:

ornidazole (the main active substance of Dazolic tablets) - 0.5 mg;

Antimicrobial property and orientation.

But doctors need to get money out ... this is their salary. And so no one says either the treatment regimen or really other answers ... everything is the same ... COME.

Chlamydia culture is used to detect infection with an antibiotic sensitivity test. The effectiveness of the analysis is from 70 to 90%.

Trichomoniasis;

In the case of vaginal preparations, it is worth saying that this will be a treatment in the form of a local treatment.

Dazolik may interact with certain medicines:

Possible complications of chlamydia:

course of treatment: at least two to three weeks

It should be noted that the last three types of harmful microorganisms belong to anaerobic microflora . that is, oxygen is not needed for the normal functioning of such cells. As a rule, these families cause particularly severe damage to the deep structures of the human body, which sometimes leads to gangrene . as an absolute therapeutic indication.

Tiberal for trichomoniasis

semen after ejaculation may contain drops of blood

changes in liver tests.

With amoebic dysentery, the course of treatment is 3 days.

Klacid

Chronic prostatitis.

"Genferon"

microcrystalline cellulose (MCC);

Reviews about Dazolik

In addition to the fact that these candles perfectly destroy chlamydia in women. they can also be used against:

to prolong the effect of vecuronium bromide, used for muscle relaxation during surgical operations;

Dazolik belongs to the group of antiprotozoal drugs and has a pronounced antibacterial activity. Its active ingredient ornidazole is able to act on protozoa, destroy their DNA structure and cause their death. This modern drug is especially effective against infectious diseases caused by Fusobacteria, Giardia, Trichomonas, Clostridia, Bacteroides and anaerobic cocci.

Some patients describe mild nausea. drowsiness. "feeling drunk" or dizzy after taking Dazolic. In rare reviews, there are references to a slight violation in the coordination of movements and an allergic reaction, which was manifested by itching of the skin of the legs.

giardiasis - 3 tablets per day (in one dose), for 1-2 days;

Synthesis of 20 auxiliary components restores the protection of internal organs

Ceftriaxone

Diagnosis of chlamydia

Adults and children weighing more than 35 kg are prescribed 3 tablets once, which should be taken in the evening.

Through intercourse

extraintestinal forms of amebiasis - 1 tablet 2 rubles / day, for 5-10 days (the doctor determines the exact duration of admission);

It is important to emphasize this, since with the availability of drugs, many patients simply begin to use suppositories uncontrollably.

The probability of infection with an infected partner is 50%.

The drug is compatible with ethanol, but it is still not recommended to take alcohol during treatment, since their interaction has not been fully studied.

Side effects

from 1 year to 6 years - 250 mg;

Skin reactions.

Antibiotic choice

Gyro;

A pharmaceutical preparation can significantly affect the coordination of movements and fine motor skills, cause impairment of consciousness, therefore, during conservative treatment, one should refuse to drive a car or other potentially dangerous mechanisms.

Stimulation of the process of birth of new antibodies.

1. Unidox - 100 mg each. 2 times a day

Reviews for Dazolik on various pharmaceutical forums are predominantly positive, because the antibiotic copes with harmful microorganisms in a short time and allows you to relatively quickly restore full working capacity and return to duty. Also, people who have been treated with this pharmaceutical preparation note an extremely small number of undesirable effects of therapy, which, moreover, do not appear in all cases of the conservative course of sanitation with Dazolik.

Adult patients and children weighing more than 35 kg are prescribed 1 tablet of Tiberal 2 times a day (morning and evening).

Quinizol (Russia);

“I can prescribe a course of treatment for you right now, in absentia, and the result will be 70-90%. the maximum course is two to three weeks and there is nothing complicated about it, urogenital chlamydia is treated with all the same drugs, only they can be called differently. These can be tetracyclines (doxycycline), macrolides (for example, azithromycin (Sumamed), fluoroquinolones.

Entamoeba histolytica (dysenteric amoeba );

convulsions;

The acute form of chlamydia appears two weeks after unprotected sexual contact with an infected partner. During this period, the following symptoms are likely:

Therefore, all candles are prescribed strictly individually and after consultation with a doctor.

In no case should you violate the regimen of taking the drug and independently reduce the course of conservative therapy prescribed by the attending physician, as in the case of sanitation with any other antibiotic. Such actions can lead to incomplete pharmaceutical action of the drug and the development of resistance to Dazolic (and the entire group of antibiotics based on ornidazole ) in harmful microorganisms, which is fraught with serious consequences. So in the case of amoebic dysentery, stronger antibiotics will be prescribed, the spectrum of side effects of which is much wider than that of this drug, which will make drug treatment more exhausting and lengthy.

Infection development algorithm

The first on our list will be the drug "Polyoxidonium". These suppositories not only affect chlamydia, they are also an immunomodulator.

Dosage of Dazolic

Aggravation of side effects;

The incubation period for chlamydia lasts from two weeks to a month. About half of the patients are unaware of the presence of the disease, since no specific symptoms are found.

10 tablets in a foil blister - 1 or 5 blisters in a carton.

Among all the symptoms that one would need to pay attention to, it is worth highlighting the appearance of vitreous discharge from the urethra (the so-called "morning drop"). The whole process of urination is accompanied by itching and burning. Pain is not excluded, but they are usually not expressed, and are concentrated in the urethra, scrotum, lower back and ovaries. Often there is an increase in temperature (usually within 37 degrees) and general weakness, as in the consideration of female symptoms indicating intoxication. In rare cases, there is clouding of the urine, as well as the manifestation of purulent threads in it. Patients may also experience spotting upon completion of urination or during ejaculation. Regardless of the nature of the manifestations and the degree of discomfort, you need to go to the doctor as soon as possible. Chlamydia spreading throughout the body can cause serious illnesses (such as infertility and impotence).

eudragit E-100 ;

Lornizol;

Trichomonas,

Causing the death of Leydig cells and narrowing of the outgoing spermatic tract, which leads to the cessation of spermagenesis and male infertility.

In the treatment of trichomoniasis, treatment is also carried out in the sexual partner. Women are advised to combine oral administration with the introduction of the drug into the vagina at night.

As its features, it is worth highlighting the gluing of the eyelids after sleep. The duration of the course of chlamydial conjunctivitis is about 4 weeks (after it there is no deterioration in vision). Many children experience respiratory chlamydia (respiratory tract infection), the symptoms of which are the result of the infection affecting the lung tissue, which is explained by the aspiration of amniotic fluid with infection during childbirth.

Dazolik and alcohol

"Genferon" is another drug in the form of suppositories that can be used both rectally and vaginally, that is, they are suitable for therapy in both sexes.

Treponema.

P olivinylpyrrolidone K90;

It is a narrowing of the urethra as a result of cicatricial changes in the urethral mucosa. Treatment takes place only through surgical intervention.

Hi all. I want to tell and tell the story of how I treated CHLAMYDIOSIS, what I encountered and how I finally diagnosed it. First. the situation is ordinary, I slept with a beautiful girl and now on the 4th day I feel itchy in the penis and the discharge is white-cloudy.

The duration of treatment is 5 days.

In addition, these suppositories belong to another type of antiviral interferon.

colloidal silicon dioxide;

As for additional symptoms, weakness is noted here, a slight increase in temperature is a characteristic symptom of intoxication. In addition, there are simply no specific symptoms or signs that would indicate the presence of chlamydia (and neither for the woman nor for her doctor).

If it is necessary to prescribe Dazolic to a nursing mother, the doctor may recommend stopping breastfeeding for the period of treatment.

upper and lower respiratory tract

purified water.

Structural analogues of Tiberal, having the same active substance - ornidazole:

1. Ornion (Russia);

Chlamydia treatment

2. organs of hearing and vision

Rectal suppositories can also be used 1 piece twice a day. The course of treatment is 10-25 days.

Of the main advantages, we note:

3. polyethylene glycol 6000;

The drug is produced by various companies, mainly Turkish and Swiss.

4. Vaginal. Such candles, of course, are prescribed exclusively for women.

For a full course of treatment of chlamydia with an active inflammatory process, a complex of medicines will be required. The drugs that are used in treatment are chosen by a specialist taking into account the clinical symptoms of the disease, the characteristics of the patient's body, the severity of inflammation and the results of all tests - liver tests, immunograms, urine cultures, complete blood counts, ELISA results, PCR and other laboratory tests.

5. Sumamed
6. coli.
7. prevention of infectious complications after surgical interventions on the intestines and gynecological operations.
8. Ferula Dzungarian destroys pathogenic viruses, fungi and bacteria
9. pregnancy (especially the first trimester);
10. age category from 7 to 12 years - 375 mg each;
11. From the gastrointestinal tract- Nausea, diarrhea. vomit. increased levels of liver enzymes;
12. From the side of the nervous system- incoordination of movements, drowsiness, dizziness, fatigue, headache. hand tremors, convulsions, muscle rigidity, short-term loss of consciousness. perversion of taste perception, neuropathy;
13. Meratin;
14. physical fatigue
15. Fusobacterium nucleatum (fusobacterium nucleoid or Plaut's wand ).

ON-LINE sites all over the world are created so that a doctor can really consult on the Internet for people who, for some reason of their own, cannot go to a paid doctor or hospital. We have everything through "one" place. Here is how, for example, internal consultation differs in my case from correspondence. I have a certificate of tests, where Chlamydia is confirmed and nothing more. And I can also name the date of infection. ALL. This is enough for 90% of all doctors to prescribe a course of treatment ... and you don’t need to show anything, everything is clear anyway.

16. Tiberal enhances the effect of hemostatic drugs (anticoagulants) of the coumarin series - Warfarin. Acenocoumarol, etc. When these drugs are co-administered with Tiberal, constant adjustment of their dose is necessary.
17. The main treatment lasts 14 days: a combination of two antibiotics, an antimycotic drug, means to stimulate digestion (Festal, Pancreatin). Reception of enzymes and vitamin complexes is not canceled.
18. painful urination

Contraindications

19. giardiasis (lesion of the small intestine, and sometimes the liver, with protozoa - giardia);

Candles completely stop all vital processes in disease-causing agents, which leads to their death.

Compound

20. impaired coordination of movements;
21. Pathogenic fungi.

08/18/2007, Mikhail

The price of Dazolik on the territory of the Russian Federation is from 260 rubles per package, the price of Dazolik tablets in Ukraine pleases a little more, because the drug can be purchased for only 40-50 hryvnia.

The drug belongs to list B of the international registry of pharmaceuticals as a potent drug, therefore, in pharmacy kiosks it is released only according to a prescription certified by the attending physician.

To date, the problem of treating chlamydia has not been fully resolved, and most experts argue that this is explained by the formation of an inadequate or pathological response of the body to the infection. Specialists in this field conducted a set of studies that showed that in 70 percent of cases there was a cure for chronic chlamydia without resorting to the use of antibiotics, that is, the infection was spontaneously treated by the body itself.

22. manifestations of neutropenia (decrease in the number of neutrophilic leukocytes);

Interaction

Drug Tiberal

Scheme of using suppositories for chlamydia

23. short-term loss of consciousness;

Patients who wrote negative reviews complain of a pronounced side effect of the drug - dizziness and various disorders of the digestive tract.

"Hexicon" is not only capable of destroying pathogenic bacteria, but also contributes to the restoration of the vaginal microflora.

An example treatment regimen is as follows:

Dazolik - instructions for use, analogues, reviews, price

Dazolik should not be used when working, requiring caution and precise coordination of movements, when driving vehicles or complex mechanisms, since ornidazole can have a depressant effect on the central nervous system. During treatment with this drug, it is better to refrain from these types of activities.

24. Strengthening the impact of antibiotics on the course of treatment.

Dazolik is taken orally, after meals, drinking plenty of water. The dosage and duration of the course of administration depends on the age, body weight and diagnosis of the patient.

Long story short… I'm disappointed… heartbroken… and even with an infection.

25. antiseptic capabilities.
26. Orgil;

So what. To say and show it, I need to go somewhere. ABSOLUTELY NO.

27. For adults and children weighing more than 35 kg, the daily dose of Tiberal is 3 tablets, which must be taken at the same time, in the evening.

In chronic gardnerellosis, adults can be prescribed a daily dose of up to 2.5 g (5 tablets). It should be divided into 2-3 doses. For women, it is recommended to combine taking pills with immunotherapy and topical treatment with creams, gels or suppositories.

Do not prescribe Tiberal in the first trimester of pregnancy and while breastfeeding.

The dosage of Tiberal for various diseases is indicated below.

Before use, you should consult with a specialist.

28. prevention and treatment of anaerobic infections during surgical operations in gynecology or on the intestines.

Dazolik, instructions for use (Method and dosage)

29. itching and burning when urinating

In the treatment of trichomoniasis, the drug is prescribed 2 times a day: in the morning and in the evening, 1 tablet. Both sexual partners are treated at the same time, regardless of the presence of signs of the disease.

Overdose

Indications for use

30. Epidymitis. Inflammation of the epididymis. It is characterized by high temperature and an increase in the appendage in volume. The inflammatory process disrupts spermatogenesis and leads to infertility. Often occurs in parallel with orchitis (testicular inflammation).
31. Others (extremely rare)- depression, peripheral neuritis, leukopenia. allergic rash or itching.

Contraindications

Separately, we say that these are suppositories for insertion into the vagina, and they are intended for women.

32. depression;

As for chlamydia itself, here Betadine suppositories always demonstrate high efficiency and rapid elimination of the disease.

The third method of research with the reliability of results up to 70% - RIF. The material is taken from the urethral canal, stained with a substance, examined under a microscope. The analysis is carried out very quickly: no longer than an hour. But the study requires a lot of tissues, and the infection must be in the acute phase: this is a significant drawback of the analysis. Sometimes a reaction to a substance is given not by chlamydia, but by staphylococci.

33. Ornigil;

Laboratory diagnostics

The most reliable results are obtained by PCR diagnostics. In this case, scrapings from the genitals are taken to determine chlamydia. Test reliability: up to 99%. The result of the analysis is known one or two days after the delivery of the material.

Tiberal with giardiasis

The name of suppositories from chlamydia

34. headache;
35. breastfeeding;

Let's talk today about which suppositories are the most effective, and what treatment regimens they offer for a woman.

36. fatigue;
37. dizziness;

"Betadine"

Instructions for the use of Dazolik differ somewhat in dosage and treatment regimen, depending on the primary disease against which conservative antibiotic therapy is being carried out.

38. The preparatory stage consists of 7 days. During this period, immunostimulants are prescribed, if necessary, an enzyme preparation (Wobenzym), baths with chlorhexidine and a multivitamin complex.

polymerase chain reaction. To date, this method has the highest reliability - up to 100%. To perform the analysis, a little material is required, and the results will be ready in 1-2 days. Although this method in rare cases can give false positive results.

The second most reliable study is the method for determining antibodies to chlamydia. ELISA or enzyme immunoassay. The advantage of this study is the determination of the stage of the disease: acute or chronic. But such an analysis is carried out only after at least 20 days after infection. Test reliability: about 60%.

Candles "Viferon" not only act as an immunomodulator, but also perfectly destroys all the structures of pathogens.

The scheme for using suppositories for chlamydia in a woman involves several basic rules.

39. sexual relations are prohibited during treatment

Thorough animal studies have shown that the drug is non-toxic and does not cause fetal abnormalities. But since no complete and comprehensive studies of the effect of Tiberal on female pregnancy and the fetus have been conducted, it is recommended that the drug be prescribed only for absolute indications.

40. sodium starch glycolate type A;

Dosage depends on age and weight.

41. prevention of anaerobic infections during surgical treatment - 1-2 tablets before surgery and 1 tablet 2 times a day after surgery, for 3-5 days.

The course of treatment with the drug, the frequency of administration depend on the diagnosis, and the dose depends on the weight of the child. Usually, the children's dose is calculated based on the body weight of the child - how much more or less than 35 kg:

During pregnancy and lactation

Against the background of these symptoms, general signs of intoxication of the body appear: weakness, fatigue, body temperature up to 37.5 °. Gradually, the signs of the disease decrease, become less pronounced. Discharge from the urethra appears only after sleep.

42. Tiberal increases the duration of action of vecuronium bromide, which is most often used to relax skeletal muscles during operations.
43. organic pathologies central nervous system.
44. amoebic dysentery - 4 tablets each with a body weight above 60 kg; 3 tablets, if the body weight is above 36 kg, 1 p./day, for 3 days;
45. joints

The fact is that initially all drugs of this type are divided into two areas, according to the type of input:

If there is no good immune response of the body to the introduction of microbes into the body, then no antibiotic will cure the patient. In the course of treatment of chlamydia, it is worthwhile to include adequate immunostimulation in a timely manner.

Suppositories for chlamydia are one of the simplest solutions in the treatment of the disease.

46. giardiasis;

Tiberal's analogs

Before we consider the symptoms of chlamydia in women, we note that in seven cases out of ten it is absent. First of all, chlamydia is manifested in women by vaginal discharge, which can be purulent or mucous. The difference from simple secretions is in the accompanying unpleasant odor, shade - it happens that such secretions have a yellowish color. Instead of discharge, pain may appear, which are noted from the external and internal genital organs. In addition, itching and burning appear (such sensations may accompany urination). A woman has a desire to scratch her skin, pains in the lower abdomen appear, which are concentrated in the pelvic region. Particularly severe pain is noted on the eve of menstruation, often bleeding, completely unrelated to menstruation (they are usually called intermenstrual bleeding).

47. Staphylococcus.

"Hexicon"

48. Weight up to 35 kg - 25 mg / kg;
49. food poisoning, chemicals, harmful fumes

For children weighing less than 12 kg, the drug is not prescribed due to the inability to split the tablet to obtain a small dose.

The latent form of chlamydia can last for months. Certain factors contribute to the transformation of the disease into an acute form:

Drugs of choice - antibiotics

Chlamydia in men - signs

50. hypersensitivity to any component of the drug;

The drug Dazolik is produced in the form of tablets (round, biconvex) of white color with a risk on one side. One tablet contains 50 mg of ornidazole.

51. Orzol;

special instructions

mini test. Each of you can purchase it at a pharmacy and conduct an analysis on your own. It is cheap, fast, but the accuracy of such tests does not exceed 20%. For this reason, it is not worth relying on its indicators;

Chlamydia are intracellular microorganisms, an intermediate link between bacteria and viruses. They are insensitive to Tiberal. Therefore, the appointment of Tiberal for chlamydia does not make sense and is a medical mistake. In some cases, Tiberal is used in the treatment of complications of chlamydia when there is a layering of another infection.

KLABAKS (clarithromycin) - the leader in the treatment of chlamydial infection, 250 mg - the first 3 days, 3 times a day, then 2 times a day, every 12 hours for 14 days. Chlamydia is a harmful virus and is not easily treated. I began to take no longer hoping for anything. But, fortunately ... on the 10th day I got up in the morning .... and that's all ... no discharge ... no symptoms.

52. Vibramycin

If a woman is infected with chlamydia while pregnant, and with a subsequent exacerbation of the process already against the background of a weakened immune system, the symptoms will be exactly the same as in non-pregnant women. Most often it is a mucopurulent form of cervicitis, endometritis with inflammation of the uterine mucosa or choriomnionitis (the placenta is inflamed).

It is worth noting that about 60% of cases indicate the transmission of the infection to the child with the further development of chlamydia.

With signs of an overdose of the drug (convulsions, peripheral neuritis, depression), the doctor recommends symptomatic therapy to the patient. When seizures occur, diazepam is prescribed.

53. Amoxiclav

Stimulation of immunity - the treatment of chronic chlamydia must necessarily include immune agents, since they are an essential component in the treatment of all sexually transmitted diseases.

Blood test for infection

Given all of the above, the question remains: how to treat chlamydia in men. Drugs of choice:

Therefore, as you already know, those sensations of a subjective character that a woman experiences regarding the genitals and the state of their certain ill-being, along with the highlighted symptoms, which may also be present, are all a reason for a subsequent visit to a gynecologist.

Release form

In our time, the treatment of chlamydia for patients and doctors presents serious difficulties, since often after therapy with antimicrobial drugs, this insidious disease re-manifests after a while. The problem is that many patients are diagnosed with chronic urogenital chlamydia, and many drugs are often ineffective.

54. children over 12 years old and adults 500 mg;

Tablets Tiberal - instructions for use, analogues, reviews, prices

55. Ornidazole Vero;

Coincidence in the ATX code of the 4th level:

56. weakness;

Children's daily dose is calculated by body weight - 25 mg / kg, and is given in one dose.

57. gardnerella,

Chlamydial infection is able to penetrate the uterus, fallopian tubes, uterine appendages, provoking an inflammatory process there - salpingo-oophoritis, endometritis, salpingitis. A distinctive feature is the formation of adhesions and scarring in the fallopian tubes, which causes tubal infertility and ectopic pregnancy.

Late treatment is fraught with consequences:

In parallel, inflammatory processes, for example, cystitis, endocervicitis and others, can be diagnosed at the reception. It is not excluded that a woman is diagnosed with bacterial vaginosis. As you may have guessed, each of these diseases can have its own symptoms, without any "binding" to chlamydia, but it is really possible to accurately check the presence of a connection only after analysis.

58. the opening of the urethra swells and turns red

Development of chlamydia

Pharmacological action

For almost the same reasons, the antiprotozoal drug has become popular with both the attending physicians of therapeutic hospitals and qualified pharmacists. It is safely prescribed in the pediatric department and for adults, since the strength of the antibiotic effect allows you to treat a wide range of pathologies and destroy harmful microflora with minimal adverse reactions.

Dazolik

59. change in color of urine (it becomes cloudy)

Preventive therapy anaerobic infections is compiled in this way - 0.5-1 g once before the operation (the exact dosage is set by the operating surgeon from the relevant indicators of the body), and then, after the operation, 500 mg 2 times a day for 3-5 days.

Chlamydia in men: symptoms

Here I accidentally come across a urologist-venereologist from a large Moscow military hospital on the Internet. I tell him everything, and he tells me the following:

60. Trichomonas vaginalis (trichomonas vaginalis );

The main constituent elements are quickly and completely (the bioavailability of the drug is a good 90 percent) absorbed from the gastrointestinal tract after oral administration. The maximum plasma concentration is reached after 1-2 hours, depending on individual parameters. metabolism . At least 15 percent of the biological substances of Dazolic binds in the blood to its proteins. 13 hours after taking the tablets, the constituent components are able to penetrate through blood-brain barrier .

61. For persons weighing more than 60 kg, the daily dose is increased to 4 tablets.

I turned to a dermovenerologist for help. I was put on doxycycline hydrochloride and metronidazole… took a week… no change. Then they prescribed TARIVID (ofloxacin). Took a week - did not help. I started injecting chlorhexedine bigluconate 0.05% into the urethra for 3 minutes. (As the doctor said)

If suddenly this drug does not help someone, the doctor said, maybe this is ... here is a comprehensive way to treat chlamydia, which did not succumb to the previous treatment.

Drugs for the treatment of chlamydia

Dazolik during pregnancy and lactation

Dazolik for children

62. Ornidazole (Russia);
63. disinfectant features.
64. sometimes there is pain in the lower back. discomfort in the groin

"Polyoxidonium"

65. periods pregnancy (especially in the first trimester) and lactation (especially breastfeeding );

Several antibiotics are always selected to treat chlamydia, because chlamydia is an unusual bacteria and does not always respond immediately to therapy. The antibiotic is selected individually for the patient and his medical history. The success of therapy depends on compliance with the rules:

Before replacing the drug with an analogue, it is necessary to consult with your doctor or, in extreme cases, with a pharmacist.

66. need to take antifungal drugs

Terms of sale

67. Prostatitis. Against the background of chlamydia, the prostate gland becomes inflamed, urination is difficult, there are pains in the groin and lower back, watery discharge. The prostate becomes sensitive to touch, painful, heterogeneous structure.

Infection may also be accompanied by complications such as abnormal placentation, untimely rupture of the membranes, or premature detachment of the placenta. In addition, intrauterine hypoxia, fever and weakness during childbirth are not excluded.

Found chlamydia, the doctor prescribed treatment

Cycloferon 10 ampoules every other day
Lidaza (mixed with novocaine) also 10 injections
Vilprafen 500 3 packs. 2 tablets per day

the course is designed for 23 days, injections are not every day, but with a certain frequency.

Knowledgeable people, what do you say? Normal course, or to address to other doctor?

About the unfriendly union of Trichomonas and Chlamydia

Among the most common sexually transmitted diseases, trichomoniasis and chlamydia occupy a leading position. The clinical manifestations of these pathologies are largely similar, and the methods of diagnosis and treatment are not very different.

The main danger of chlamydia and trichomoniasis is that they negatively affect the human reproductive system, so you should know the methods of prevention to avoid infection.

Relationship between trichomoniasis and chlamydia

Symptoms of both pathologies are more pronounced in women, in men they often occur in a latent form, without any special signs, which makes timely treatment difficult.

Are trichomoniasis and chlamydia the same thing? Both infections can develop at the same time, since chlamydia and Trichomonas often live simultaneously in the human body.

Pulling pain in the lower abdomen, sometimes in the anal region, pain during urination, swelling of the external genitalia.

Fever, profuse discharge with impurities of pus, blood with a pungent odor.

Disruptions in the menstrual cycle.

In advanced forms of the disease, cystitis and pyelonephritis develop.

On examination, the doctor can see many small hemorrhages on the cervix.

Itching, discomfort in the genital area, groin, pain can radiate to the back, leg, discomfort during intercourse, urination.

Inflammation of the foreskin

copious discharge from the urethra, most often in the morning.

With a weakened immune system, the temperature rises, with prolonged infection, discharge from the urethra appears, the quality of sperm deteriorates, and there are problems with potency.

Signs of chlamydia

Drawing pain in the lower abdomen, discomfort during intercourse.

Atypical vaginal discharge, yellow, green, frothy,

the appearance of white plaque, ulcers on the external genitalia.

Discharge of much mucus from the urethra, sometimes with pus.

Burning, cutting when emptying the bladder due to severe inflammation of the urethra.

The head of the penis swells, turns red,

during sex there is severe pain.

General weakness, subfebrile temperature.

Combined infection treatment

If unpleasant symptoms appear, it is necessary to visit a gynecologist, urologist or venereologist. Diagnosis of diseases that are sexually transmitted includes taking a smear from the vagina, urethra, cervical, urethra, PCR, clinical blood and urine tests.

Based on the results obtained, the doctor selects drugs that can destroy all types of pathogenic microorganisms.

If treatment is not started in a timely manner, then in men, against the background of sexual infections, urethritis, prostatitis develop, sexual desire decreases, and infertility is possible.

The inflammatory process covers the testicles, seminal vesicles. In women, trichomoniasis and chlamydia can cause adhesions, inability to conceive. Pathogenic microorganisms can cause miscarriage or premature birth during pregnancy.

How to expel chlamydia?

For the treatment of chlamydia, antibacterial drugs are used, so that the therapy is effective, it is necessary to first do tests for the sensitivity of microorganisms to the active substance of the drug.

The drug of choice in the treatment of chlamydia is often Doxycycline from the tetracycline group. Despite the long-term use of this medicine, pathogenic microorganisms have not developed immunity to it. Reception schedule - on the first day, 200 mg in the morning and evening, then 100 mg twice a day.

Helpful in dealing with chlamydia Azithromycin (Sumamed) - on the first day, 500 mg of the drug should be taken in the morning and evening, then 500 mg once a day every other day for a week.

How to treat chlamydia:

• macrolides - Clarithromycin, Fromilid, 500 mg twice a day for 7 days;
• rifamycins - Rifampicin;
• fluoroquinols - Ciprofloxacin, Tsiprobay, Ofloxacin;
• antimycotic drugs - Flucostat, 50 mg once a day for a week;
• candles - Hexicon, Vagilak, administered anally or vaginally;
• means for the restoration of microflora - Linex, Hilak-forte;
• local preparations - Erythromycin, Tetracycline ointment.

The average duration of therapy for chlamydia is 1-2 weeks. Additionally, immunomodulators, vitamin complexes are prescribed.

Used in the treatment of chlamydia in pregnant women Erythromycin- 500 mg every 6 hours for a week, or 250 mg four times a day for 2 weeks. The same drug is also used to treat children - the dosage is 50 mg / kg. Reception should be continued for 10-14 days.

In chronic chlamydia, before starting antibiotic therapy, a course of injections is preliminarily carried out Polyoxidonium or appoint Interferon to strengthen the patient's immune system.

Reliable ways to get rid of Trichomonas

The main drug for the treatment of trichomoniasis - Metronidazole and its derivatives. The medicine is released in the form of tablets and vaginal suppositories, which allows you to effectively treat the infection in women and men. The duration of treatment is 7-14 days.

Used as adjuncts Tinidazole, Ornidazole, Macmirror, antibiotics from the tetracycline group.

Is it possible to treat venereal diseases with folk remedies?

Alternative medicine methods will not help get rid of chlamydia and Trichomonas, but they can enhance the therapeutic effect of drugs, speed up the healing process.

One of the effective methods of combating genital infections is douching with garlic tincture. It should be poured with 500 ml of alcohol 50 minced garlic, sent to a dark place for 14 days, shaken daily.

Strain the resulting tincture, dilute with water in a ratio of 1:10 before the procedure. For one session, 300 ml of solution will be required.

Juice therapy also helps a lot - add 60 ml of beetroot and cranberry juice to 120 ml of blackcurrant juice. Drink a drink in the morning and evening after meals for a month. This method of treatment helps to strengthen the immune system, is effective in chronic infections.

Prevention of STDs

To avoid infection with sexually transmitted diseases, you must be careful about choosing a sexual partner, use barrier contraceptives, do not use other people's underwear, washcloths, towels.

The story of a qualified specialist about the treatment of combined STIs:

Strict observance of the rules of personal hygiene is the main rule for preventing various sexual infections.

Prevention of sexually transmitted diseases consists in regular visits to the doctor, partners should pass all the necessary tests at the stage of pregnancy planning in order to avoid miscarriage, premature birth, infection of the fetus.

Trichomoniasis and chlamydia are dangerous sexually transmitted diseases that negatively affect the functioning of the genitourinary and reproductive systems. Can diseases be cured forever?

Alternative opinion. Visiting Dr. Komarovsky, obstetrician-gynecologist Sergei Baksheev talks about commercial diagnoses in gynecology, among which he names chlamydia:

With timely diagnosis and proper therapy, it is possible to get rid of pathologies without consequences and complications in 2 weeks. If you start the infectious process, then it will turn into a chronic form, it will take a long and not always successful treatment.

Ornidazole: reviews for giardiasis

For the treatment of bacterial infections of various localizations (genitourinary system, abdominal cavity, upper respiratory tract), preparations based on such an active substance as ornidazole, which is compatible with many other drugs, are used. This allows more effective drug therapy in case of severe diseases.

Ornidazole is a nitroimidazole group of antibiotics, which has a high activity against anaerobic bacteria, as well as against pathogens of protozoal infections. It penetrates almost all fluids and tissues of the body and is already active three hours after a single dose. This active substance is excreted within five days after the first dose.

A drug such as Ornidazole has positive reviews, although it has a rather large range of side effects. Therefore, the patient is obliged to notify the attending physician about the existing chronic diseases in order to adjust the treatment.

Active ingredient: ornidazole

This medicinal substance is used for antibacterial and antiprotozoal therapy, providing bactericidal, as well as bacteriostatic effects. When taken orally, almost 95% is absorbed from the digestive tract.

Due to the rather high penetration of ornidazole into almost all tissues and organs, this allows it to be prescribed for pathological processes of any localization that have arisen due to protozoal or anaerobic infections.

The most popular and cheapest drug based on the above active ingredient is Ornidazole obl, which has a lot of analogues, but they are more expensive.

Doctors prescribe this drug in the fight against such diseases:

• infections of the genitourinary system;
• purulent-inflammatory processes of the small pelvis in women;
• amoebic dysentery;
• giardiasis;
• amoebic abscess of the liver and brain;
• prevention of infectious infections during operations.

The action of such a drug disrupts the processes of DNA replication and transcription, has a cytotoxic effect, and also destroys the processes of cellular respiration of bacterial microorganisms. Thanks to this, a bacteriostatic effect is also achieved.

On the basis of ornidazole, there are a large number of drugs that can be supplemented with other active substances, which expands their spectrum of action. To do this, below are full descriptions of various drug combinations with ornidazole, as well as other drugs from the fluoroquinolone series.

Ornidazole ofloxacin

There is a group of drugs based on active ingredients - ornidazole and ofloxacin, for example:

Such drugs are well tolerated even by the elderly and seriously ill patients. They are perfect for the treatment of mixed infectious diseases, where combined antibacterial agents are required, which are embodied in the above preparations.

Ofloxacin rarely develops resistance to pathogenic microorganisms. Its bioavailability after oral administration is about 98% and is completely absorbed from the digestive tract.

Ofloxacin was the first antibacterial drug based on fluoroquinol. At present, medicines based on fluoroquinol are the most common for the treatment of infectious diseases and pyoinflammatory processes.

This active substance covers gram-negative as well as gram-positive aerobic and anaerobic microorganisms. It can penetrate into the tissues of the female internal genital organs (uterus, ovaries, fallopian tubes), which allows its use in the field of gynecological diseases.

Preparations such as Iflox, Polymic and their analogues can be used in various branches of medicine, and in cases where a powerful and effective antibacterial agent is required.

In urology, the above drugs are treated:

• chronic and acute pyelonephritis;
• cystitis;
• urethritis;
• various urinary tract infections, etc.

They are also prescribed for the treatment of sexually transmitted diseases, which are caused by:

1. gonococci;
2. chlamydia and other pathogenic microorganisms.

It is worth noting that the active ingredients ornidazole and ofloxacin perfectly complement each other in the fight against various infections and allow doctors to prescribe it as the main therapy.

At the same time, drugs based on them are distinguished by a low price.

Ciprofloxacin Ornidazole

Drugs based on ciprofloxacin and ornidazole are considered complex antimicrobial and antiprotozoal agents that have a wide spectrum of action against infectious diseases of various etiologies.

These drugs include:

They are identical in composition (analogues), and the price of Orcipol will be 155 rubles, and its analogue Combiflox 650 rubles.

The active substance ciprofloxacin belongs to the second generation of fluoroquinolone. It inhibits the synthesis of bacterial DNA and inhibits them, which contributes to a morphological change in the membrane and cell wall of a harmful bacterium. All this leads to her death.

Ciprofloxacin acts on bacteria, both in a state of growth and in a state of rest. It has a broad spectrum of antimicrobial activity and penetrates into almost all tissues and body fluids.

About half of the drug is excreted in the urine, 20% in the feces. The half-life of ciprofloxacin is 3 to 5 hours. If this active substance is taken by people of advanced age, or with the presence of liver diseases, then the half-life can be delayed up to 8 hours.

Ciprofloxacin ornidazole together fights well with the following diseases:

1. abdominal infections;
2. infections of the pelvic organs (uterus, fallopian tubes, ovaries);
3. gonorrhea, chlamydia, prostatitis, cystitis;
4. infections of ENT organs (bronchitis, pneumonia, etc.);
5. infections of the skin, mucous membranes;
6. sepsis.

A drug such as Orcipol (based on ciprofloxacin and ornidazole) is prescribed in the postoperative period to prevent the development of infections.

The instructions for use are quite simple, but the patient needs to carefully read it, due to the fact that different doses of the drug are needed for different diseases.

Instructions for use of tablets

What remains unchanged is that the tablets should be taken orally two hours before meals, or after. They can not be chewed and divided in half. On average, the course of treatment ranges from 5 to 7 days.

If drug therapy is prescribed in tablets, then they should be taken 1 pc. twice a day. After the disappearance of clinical symptoms, continue the course of treatment for another three days.

In the case when the attending physician has not prescribed a dosage, it is worth following the instructions with such daily doses: for adults, for infections of the urinary tract and genital organs, 1 tablet twice a day, with an equal interval of time. With cystitis (before menopause), uncomplicated gonorrhea, 1 tablet once.

For children, the daily dose is calculated according to their body weight, 10 to 20 mg/kg every 12 hours. The maximum dose of the active substance ciprofloxacin should not exceed 750 mg per day.

For elderly people, that is, over 65 years old, the dosage should be prescribed only by a doctor and be as low as possible.

1. children under the age of 15;
2. pregnant women;
3. lactation period.

Only the attending physician can prescribe Orcipol to the above categories of people, assessing the risk-benefit ratio of the patient.

Metronidazole

Metrodinazole is an antimicrobial, antiprotozoal and antiulcer drug.

The active substance metrodinazole interacts with the DNA cells of harmful microorganisms, inhibiting their synthesis of nucleic acids, which causes the death of microorganisms.

Preparations that contain metrodinazole are presented below, they can be administered to the body by oral, local, rectal and intravenous routes:

The drug is active against many gram-positive bacteria, as well as against Trichomonas vaginalis, Gardnerella vaginalis, Giardia intestinalis, Entamoeba histolytica, obligate anaerobic bacteria such as Bacteroides spp. (including Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp., Veillonela spp., and Helicobacter pylori, which promotes ulcer formation.

Metronidazole after oral administration is well absorbed into the gastrointestinal tract and penetrates into almost all tissues and body fluids. That is why, its intake is contraindicated during lactation, due to the release of the active substance into breast milk. Within eight hours, about half of the drug is excreted, of which 60% is through the urine.

The spectrum of application of the active substance metrodinazole is quite wide. It is prescribed for such diseases:

1. giardiasis;
2. liver abscesses;
3. infections of the pelvic organs;
4. abdominal infections;
5. prevention of infectious infections in the postoperative period.

For patients who have problems with the liver, it is necessary to adjust the dosage regimen of the drug, by monitoring it in the blood serum.

Metronidazole for chlamydia is prescribed quite often and is considered one of the most effective drugs for this disease, although this disease is not indicated in the instructions. All this is due to the fact that chlamydia itself is often burdened with other infections.

Usually, drug therapy is supplemented with drugs based on amoxicillin, due to which the development of resistance to the active substance metrodinazole is suppressed in bacteria.

When it is taken, the following side effects may occur:

• taste of metal in the mouth;
• disorder of the gastrointestinal tract;
• headache;
• allergic rash;
• insomnia or fatigue.

If one of these factors occurs, then a patient diagnosed with chlamydia should notify the attending physician.

Norfloxacin

This active substance also belongs to the fluoroquinolone series of antibiotics, and is a broad-spectrum antibacterial agent. Based on it, there is a frequently prescribed drug - Nolicin, which is used for such diseases:

1. chronic and acute infections of the genitourinary system;
2. gonorrhea;
3. recurrence of the urinary tract;
4. gastroenteritis, bacterial etiology.

Nolicin differs in that it has relatively few side effects: disruption of the gastrointestinal tract, an allergic reaction, a disorder of the nervous system, a change in the blood and urine formula (reversible) and a violation of the heart rhythm.

Such a drug is not prescribed for children under the age of 15, pregnant women and during the lactation period, since the main active substance is absorbed into almost all tissues and fluids, which can harm the fetus. Metronidazole, as the main drug from Ornidazole analogues, will be discussed in the video in this article.

Ornidazole in the treatment of chlamydia

Respond those who nevertheless managed to cure chlamydia. Do such people exist in real life?

02/26/2009 00:00, Olya
Hello, I have been treated for trash for almost 3 years, I want to kill doctors! Thoughts of suicide even were and are. I infected my boyfriend, he is also treated. Please tell me what to do?

03/04/2009 00:00, Roma
People tell me what is good for the eyes with rubbish?

03/05/2009 00:00, eurika
hello! you are a happy person! for many years I don’t know what to do, my hands drop, I don’t want to live. if you could recover, then this rubbish is still curable!! write me, help with advice!

What is the treatment for trichomoniasis and chlamydia?

Infectious diseases trichomoniasis and chlamydia are very similar, but at the same time, they have slightly different clinical manifestations and features of therapy. This article will tell about what trichomoniasis and chlamydia are, how to treat them.

Characteristics of diseases

Trichomoniasis is a very common acute infectious disease. The main way of infection with them is unprotected sexual intercourse (traditional sex) with the carrier of the infection. As for the transmission of the disease through oral or anal sex, this is unlikely.

Important! Trichomoniasis is genital infection. For this reason, they cannot be infected through shaking hands, sharing utensils or kissing.

Despite this, there is a small risk of transmission of the disease when using someone else's underwear, using a wet washcloth, towels and visiting the bath. This is justified by the fact that Trichomonas is able to actively live in a humid environment for several more hours.

In the event that the infection with this disease occurred in a domestic way, then, as a rule, a person does not even know about it and finds out during a routine diagnosis. In most cases, then the infection has already acquired a chronic form.

After the penetration of Trichomonas into the human body, the incubation period begins. It lasts for 2-3 weeks. At this time, pathogenic bacteria adapt to a new habitat, after which they begin to actively make themselves felt.

During the incubation period of the bacterium, the patient does not feel any signs of the disease.

As for chlamydia, it is also infectious sexually transmitted disease. It is characteristic that the causative agents of this infection - chlamydia, can affect not only the genitals (vagina, cervix), but also the rectum, urethra in men and eyes.

Carefully! Chlamydia is considered an extremely common disease.

According to studies, it is observed in 10% of people under thirty who are sexually active.

Most susceptible to this infection are those people who often change sexual partners and practice sex without barrier contraception (condom).

You should know that the most common chlamydia infection occurs during intimate intercourse (traditional or anal, it does not make much difference, since the probability of transmission of the infection is equally high in both cases).

In addition, chlamydia can also be transmitted from mother to newborn child through sexual contact. In this condition, the baby has a high risk of developing pneumonia and eye diseases.

The household route of transmission of such an infection is not excluded, but it is unlikely. This is justified by the fact that these pathogenic bacteria die very quickly when they are outside the human body.

Moreover, for a full-fledged infection, it is necessary that a large number of active chlamydia penetrate the body. Otherwise, infection will not occur.

After chlamydia enters the body, the incubation period begins. It may take one to three weeks for the first symptoms to develop.

Symptoms of trichomoniasis

Manifestations and general symptoms of trichomoniasis are not much different from traditional pathologies of the genitourinary system. Moreover, very often this infection is confused with gonorrhea, since the signs of these pathologies are also quite similar.

Reference! A very important role in the features of the manifestation of trichomoniasis is played by the form of its course. Thus, a person can have an acute infection, a chronic infection, and a condition such as a carrier state, when a man or woman does not get sick themselves, but can infect other people.

The acute type of infection is manifested by pronounced symptoms.

Women may experience the following symptoms:

In men, the acute form of this disease can provoke the following symptoms:

• Weakness and pain when urinating.
• Decreased sex drive and prostate problems.
• Burning during intimate intercourse.
• The appearance of unpleasant discharge from the urethra, which most often occurs in the morning.
• Fever and fever occurs with a weakened immune system, when infections are very easy to infect the body.

In the chronic form of the course, trichomoniasis has the same symptoms as in the acute one, but they are mild and the person may not even pay attention to them.

As a rule, the chronic form of such a disease is detected already when it began to cause dangerous complications. That is why infectious disease specialists strongly recommend regularly taking a preventive test for trichomoniasis, even if a person, at first glance, is not bothered by any signs of pathology.

In the event that a person is only a carrier of such a disease, then the least harm is done to his body. Thanks to a strong immune system, he will not suffer from the consequences of trichomoniasis, however, in the event of a sharp decrease in immunity, the disease can again become acute.

Symptoms and signs of chlamydia

Chlamydia (trichomoniasis, its symptoms are very similar to this disease) is characterized by a sluggish course, so most patients learn that they are infected by accident.

This infection can occur in acute and chronic forms, each of which has its own symptoms.

During an acute course, men may develop the following signs of the disease:

• Hyperemia of the urethra and its severe inflammation.
• Swelling of the head of the penis.
• The appearance of unpleasant mucous or purulent discharge from the urethra.
• Pain when urinating.
• General deterioration of health and fever.
• Weakness.

Attention! In advanced form, chronic chlamydia in men will not cause acute symptoms, but it can provoke the development of prostatitis, proctitis and urethritis.

In women, acute chlamydia usually presents with the following symptoms:

• Discomfort during intercourse and pain during urination.
• Inflammation of the genitals.
• Drawing pain in lower abdomen.
• The appearance of vaginal discharge, which has a specific character.

Carefully! Untreated chlamydia, both in men and women, can cause a very dangerous complication in the form of infertility.

That is why it is important to respond to its manifestations in time and treat this disease.

It should also be noted that sometimes such an infection for a long time may not manifest itself at all, that is, proceed without symptoms. For this reason, every six months, both sexual partners need to take a preventive analysis.

Chlamydia treatment

Treatment when chlamydia is detected largely depends on the form of the disease, its neglect, symptoms and the presence of concomitant pathologies in a person. Thus, therapy is selected for each patient individually.

Treatment of chlamydia is aimed at suppressing the activity of chlamydia and preventing the development of dangerous complications.

At the same time, it is worth remembering that chlamydia themselves are highly resistant to many drugs, so the doctor must supervise the therapy and replace the medicine with another if it is not effective enough.

To eliminate chlamydia, you can use the following drugs:

1. Medicines Doxycycline and Azithromycin. They are most often used to treat chlamydia. Usually, they are prescribed in combination and used for several weeks.
2. Macrolide antibiotics (Rifampicin) are considered very effective. The duration of their intake in acute infections should be at least two weeks. In the case of a chronic disease, a person needs to take such drugs in courses.
3. For general support of the body, the patient must be prescribed immunomodulatory drugs.
4. Additional drugs that can be prescribed for chlamydia are: Kladitz, Metaklin, Lomefloxacin. Dosage and method of administration is selected separately for each patient.

It is impossible to self-medicate the disease.

Important! The second sexual partner is also recommended to be tested for chlamydia and, if necessary, treated.

Treatment of trichomoniasis

The following drugs are commonly used to treat trichomoniasis:

The regimen for taking these drugs and the duration of treatment is selected individually for each patient.

Also, as a supplement, local and symptomatic therapy can be carried out.

Conclusion

Chlamydia and trichomoniasis, the treatment of which must be controlled by a doctor, requires maximum endurance and patience from the patient, since general therapy is often lengthy and complex.

View Full Version: Chlamydia treatment regimens

Good night dear experts.
It has long been manifested by the "seasons" of exacerbation with discharge. At the end of urination, cloudy white sediment and burning. In the last fateful year February 2017. There was work at a height in frost -15-25 degrees. All day. About 1.5 months. caught a strong exacerbation, and began to re-try to recover. This disease has been around for about 10 years. I didn’t know before what the eggs hurt or, as they say, the prostate. And I didn’t even think that I already had chronic prostatitis. He always stood properly, and spat everyone regularly)))
And so has handed over a smear on IPPP - it is pure or clean. After, a smear on the tank sowing - clean. After three days with a provocation, a smear from the urethra for PCR, for 6 pathogens:
Chlamydia, ureaplasma, mycoplasma, trichomonas, gardnerella and candida.

Everything is clean, except for the gardnerella.
They appointed a course, as for me weak:

Azithromycin 500 three days, 1 ton per day
Trichopolum 500mg 2 times a day for 5 days.
And I don’t remember the dosage of ornidazole for 5 days.
So when I ate azithromycin it went very well. He was 99% healthy. On day 5, the symptoms began to return. After stopping the course after two days, exacerbation and discharge like flakes:

Assigns doctor Itrakon for 5 days.
And here, after the course, I catch the strongest exacerbation three days after the end of Itracon.

Milk came out directly when urinating.
Urine tests for culture tank, high titers of opportunistic bacteria:

They prescribed injections of Ceftractam 1.5 grams 2 per day for 5 days. I almost hung myself from the pain.
Then they transferred to Suprax Solutab tablets for 10 days. And after Levomak 500mg. 10 days. (I also think it’s not enough) according to the instructions for hp, you need to eat it for 28 days. Rather, they developed resistance.

The pains generally subsided, but the left egg sank. I went to a venereologist and decided empirically to bang on Trichomonas.

Intravenous metronidazole 5 days once a day, in parallel with this standard dosage ornidazole tablets, also in parallel with azithromycin 500 mg. 1 time per day for 6 days according to the 3-2-3 scheme, that is, I drink for three days, pause for two, and drink again for three days. And in parallel, he drank Macmirror for 14 days, but he could not drink 14, only 11 days.

After this course, the symptoms subsided normally, but still manifested. I decided a month later to donate blood for antibodies by ELISA.

Antibodies to chlamydia are huge exceeding the threshold values. Ten times lg G
. It can mean that chlamydias have deeply sat down and they ptsrom are not defined any more? And only IFA? It is a lot of where read that and is with chlamydias, type infection this still that.

By the way, before the course of antitrichomonas, he began to drink tsifran od 1000 mg. By sensitivity, but he gave a strong exacerbation on the third day of admission and it was decided to cancel and take empirically.

So at the moment the sores:
Chronic prostatitis
Bilateral adnexal cyst.

I think that this is all after that first weak course and itracon, which caused an aggravation.
And I also think that it was necessary to include immunomodulators in the course.
At the moment, doxycycline (Unidox Solutab) was prescribed, I have been drinking for 11 days the first two doses of 200 mg, a loading dose, followed by 100 mg. Twice a day and take omnic in parallel. These half a year, constant chronic fatigue is especially evident after one in the afternoon. In the evening I already ate my legs and dragged home. My work is not hard. What should be taken with chlamydia biseptol or levofloxacin the same? According to the sensitivity of the flora, levofloxacin is suitable according to the latest analysis. According to reviews, Biseptol saved many (those who have already eaten all possible pills).

The ELISA method is not used to diagnose chlamydia.

The only reliable way to diagnose chlamydia is to detect chlamydia DNA or RNA in a scraping from the urethra or in the sediment of the first portion of urine by PCR.

I know this well, I took a swab from the urethra twice with a provocation with cycloferon.
I want to take real-time PCR with a three-day provocation. Tell me, will this lab and this discussion package be good?

ANDROFLOR includes:

MBP, Lactobacillus spp., Staphylococcus spp., Streptococcus spp., Corynebacterium spp., Gardnerella vaginalis, Megasphaera spp. / Veilonella spp. / Dialister spp., Sneathia spp. / Leptotrihia spp. / Fusobacterium spp., Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, Atopobium cluster, Bacteroides spp. /Porphyromonas spp. / Prevotella spp., Anaerococcus spp., Peptostreptococcus spp. / Parvimonas spp., Eubacterium spp., Haemophilus spp., Pseudomonas aeruginosa / Ralstonia spp. / Burkholderia spp., Enterobacteriaceae spp. / Enterococcus spp., Candida spp., Mycoplasma genitalium, Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis+ KVM

It seems that the list is impressive, and the price for our region too))