What percentage is iodine. Iodine: instructions for use

Latin name: Iodum
ATX code: D08AG03
Active substance: Iodine
Manufacturer: Yaroslavl pharmaceutical factory,
Update PFC and others, Russia
Pharmacy leave condition: Over the counter

Physical properties of iodine: a solid substance, the crystals (plates) of which are black-gray with a purple tint and a specific smell. Getting iodine in a liquid state occurs by heating under pressure. Scientists have established what the melting point is - 113.5 ° C.

Crystalline iodine and its alcohol solution have a bactericidal effect, reduce the risk of rotting and hardening of the skin upon drying (cauterizing and tanning properties), anti-inflammatory and local irritating effects.

What is the body's iodine made from?

There are the following ways:

– Processing of seaweed (kelp)

– Extraction from natural solutions containing iodine (sea waters, salt lakes)

— Ionic method

- Obtaining iodine (technical) for the needs of the national economy from the waste of saltpeter production.

Indications for use

An alcoholic solution of iodine is recommended as an antiseptic - treatment of the skin around the wound, the hands of the surgeon or the area of ​​the body within which surgery is performed, and an anti-inflammatory substance. The tool can be used for the following indications:

Diseases of the nasal mucosa (ozena)

Third period of syphilis (tertiary)

Chronic disease of the blood vessels, accompanied by the deposition of cholesterol plaques

Accumulation of cellular elements with an admixture of blood and lymph in the inflammatory area of ​​the skin (inflammatory infiltrate)

Atrophy of the larynx

Chronic lead or mercury toxemia.

The composition of the drug

One milliliter of a five percent alcohol solution contains 50 mg of iodine, as well as additional substances: 96 percent ethyl alcohol, potassium iodide and distilled water.

Medicinal properties

Iodine is necessary to maintain the physiological state of the thyroid gland is normal. Entering the body along with nutritious foods, it becomes part of the hormones triiodothyronine and thyroxine. It has a hypolipidemic effect - it reduces the concentration of lipids, which has a beneficial effect on protein and lipid metabolism.

Iodine is one of the strongest antiseptics, used for cauterization and tanning of the skin. In medicine, the use of I is due to irritating abilities, that is, an exciting effect on the nerve endings of the skin, mucous membranes, as well as a distracting effect - weakening the pain syndrome in the affected tissues.

The tool has the property of protein coagulation (coagulation), which causes their death. Therefore, iodine is widely used in the treatment of fungal diseases, since the fungus that affects the skin epidermis and the nail plate has a protein environment. Positively proved I in the treatment of papillomas.

The substance is excreted through the kidneys, intestines and external secretion glands - milk and sweat.

Release form

The price of iodine in glass is an average of 15 rubles, in a bottle with a shaving valve - 24 rubles, a marker with l - 40 rubles.

Iodine is available as an alcohol solution of 5, 3, 2 and 1%. Liquid for external use has a red-brown color with a characteristic odor.

Pharmaceutical companies offer the following packages for sale:

Dark glass bottle. The form has a significant drawback - when uncorked, it leaves marks on the skin. Additional application tools are required, such as cotton swabs.

Tube-dropper. After use, drops of the solution are retained in the valve, which may spill out during the next application.

Medical bottle-pencil. Leaves no residue, easy to use. The disadvantage is that it dries instantly if the cap is not tightly closed.

Mode of application

The instruction recommends that when applying the substance externally, in the solution, moisten a cotton swab, which is used to treat damaged tissues. To use iodine for medicinal purposes inside should be after eating, after mixing with milk. The dosage is prescribed by the doctor individually, depending on the pathology.

In the fight against atherosclerosis, 10-12 drops are prescribed three times a day.

When treating papillomas with iodine, the neoplasm dies off after 14 days. Before use, the nipple-like growth should be washed with soapy water and dried thoroughly, the skin around should be greased with a greasy cream and then applied directly to the formation.

Iodine mesh is effective for sprains, abrasions, respiratory viral infections, diseases of the upper respiratory tract. When applied, l penetrates through the skin and is absorbed into the blood, thereby activating blood flow, relieves inflammation and swelling. Indicated for use from the age of one.

An effective remedy for relieving the symptoms of sore throat is gargling 3-4 times a day with a solution prepared as follows: mix 250 ml of boiled water (cooled to a temperature of 36-37 ° C), 3 drops of iodine and 1 teaspoon of soda and salt. Do not eat or drink for 30 minutes after application.

During pregnancy and breastfeeding

Use in the lactation period is permissible if the benefit to the mother outweighs the potential danger to the child. It should be borne in mind that the substance is excreted in breast milk, so it is necessary to consult a medical specialist. The instruction does not recommend the use of iodine during pregnancy.

Contraindications

• Individual intolerance
• Children's age up to 5 years for oral administration and up to 1 year for external use
• Hyperthyroidism (too much thyroid hormone in the body)
• Duhring's disease (dermatitis herpetiformis)
• Treatment of trophic ulcers, including diabetes mellitus.

Precautionary measures

Use for the treatment of mucous membranes requires supervision, since the alcohol contained in the composition can cause severe burns and irritation. Avoid contact with eyes.

Cross drug interactions

Iodine is pharmaceutically incompatible with ammonia solution, essential oils and mercury amidochloride (an explosive mixture is formed upon interaction).

Side effects and overdose

Allergic reactions are possible. With prolonged use - iodism (iodine poisoning), the consequence of which is the manifestation of diseases such as urticaria, angioedema, increased salivation and the production of lacrimal fluid, acne.

An overdose can be observed both after ingestion l, and by inhalation of vapors.

Symptoms of exceeding the permissible dose when using a concentrated solution inside: a burn of the digestive tract, erythrocytosis, the appearance of hemoglobin in the urine.

Overdose by inhalation of iodine vapor can cause a complete contraction of the muscles of the larynx (laryngospasm), a burn of the upper respiratory tract, an aseptic inflammatory process in those parts of the mucous membrane where iodine is released.

Dose leading to death - 3 g.

Treatment is symptomatic, it is necessary to wash off the excess of the substance with running water. In case of poisoning, antishock therapy is used, aimed at reducing the irritation of the receptors.

Terms and conditions of storage

Iodine should be stored out of the reach of children, protected from light and fire, at a temperature not exceeding 25 °C. The drug is valid for 36 months from the date of manufacture.

Ultraviolet radiation and air temperature above 40 ° C accelerate the process of decomposition of active iodine. Discoloration of the solution indicates a decrease in the effectiveness of the agent.

Analogues

Among antiseptics, there are many analogues of iodine, which also have antimicrobial and anti-inflammatory properties. The most popular are:

Betadine

Producer - EGIS Pharmaceuticals PLC, Hungary.

Price solution on average for 30 ml - 175 rubles.

The active substance is povidone-iodine. The drug has a disinfectant and antiseptic effect. Available in the form of a solution, ointment and vaginal suppositories.

Pros:

• No side effects
• Variety of forms.

Minuses:

• The product may stain clothing.

Povidone-iodine

Producer - Hemofarm D.O.O. Sabac, Serbia.

Price in Russian pharmacies on average: a liquid preparation - 450 rubles, suppositories - 495 rubles.

It has antiseptic and disinfectant action. Not contraindicated for the treatment of trophic and diabetic ulcers, bedsores. According to messages on the forums of patients and specialists in medicine, the drug in the form of suppositories is effective for the treatment of vaginal candidiasis, genital herpes. Women note that after 3-4 days of use, the symptoms are significantly reduced, the amount of discharge, discomfort, and redness of the mucosa decrease.

Pros:

• Fast results.

Minuses:

• May cause itching and irritation.

Name:

Iodine (lodum)

Pharmacological
action:

Elemental iodine has pronounced antimicrobial properties. Elemental iodine preparations are characterized by a pronounced local irritating effect on tissues, and in high concentrations - a cauterizing effect. Local action is due to the ability of elemental iodine to precipitate tissue proteins. Preparations that split off elemental iodine have a much less pronounced irritant effect, and iodides have local irritating properties only in very high concentrations.
The nature of the resorptive action preparations of elemental iodine and iodides is the same. The most pronounced effect in the resorptive action of iodine preparations is on the function of the thyroid gland. With iodine deficiency iodides contribute to the restoration of impaired synthesis of thyroid hormones. With a normal iodine content in the environment, iodides inhibit the synthesis of thyroid hormones, the sensitivity of the thyroid gland to pituitary TSH decreases and its secretion by the pituitary gland is blocked. The effect of iodine preparations on metabolism is manifested by an increase in dissimilation processes. In atherosclerosis, they cause some decrease in the concentration of cholesterol and beta-lipoproteins in the blood; in addition, they increase the fibrinolytic and lipoproteinase activity of blood serum and slow down the rate of blood clotting.
Accumulating in syphilitic gums, iodine contributes to their softening and resorption. However, the accumulation of iodine in tuberculous foci leads to an increase in the inflammatory process in them. The excretion of iodine by the excretory glands is accompanied by irritation of the glandular tissue and increased secretion. This is due to the expectorant effect and stimulation of lactation (in small doses). However, in large doses, iodine preparations can cause lactation suppression.

Pharmacokinetics
Upon contact with the skin or mucous membranes, 30% turns into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs and is selectively absorbed by the thyroid gland. It is excreted mainly by the kidneys, intestines, sweat and mammary glands.

Indications for
application:

Iodine preparations are used externally and internally:
Outwardly used as antiseptic (disinfecting), irritating and distracting agents for inflammatory and other diseases of the skin and mucous membranes.
inside- with atherosclerosis, chronic inflammatory processes in the respiratory tract, with tertiary syphilis, hyperthyroidism (thyroid disease), for the prevention and treatment of endemic goiter (thyroid disease due to low iodine content in water), with chronic mercury and lead poisoning.

Mode of application:

For external use iodine treat damaged areas of the skin.
For oral administration the dose is set individually, depending on the indications and the age of the patient.
Locally used for washing lacunae and supratonsillar spaces - 4-5 procedures at intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for instillation into the ear and washing - for 2-4 weeks; in surgical practice and in case of burns, gauze wipes applied to the affected surface are moistened as needed.

Side effects:

For external use: rarely - skin irritation; with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).
When taken orally: allergic skin reactions, tachycardia, nervousness, sleep disturbances, excessive sweating, diarrhea (in patients over 40 years of age).

Contraindications:

Hypersensitivity to iodine. For oral administration - pulmonary tuberculosis, nephritis, nephrosis, adenomas (including the thyroid gland), furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, pregnancy, children under 5 years of age.

Interaction
other medicinal
by other means:

Pharmaceutically incompatible with essential oils, ammonia solutions, white sedimentary mercury (an explosive mixture is formed). Alkaline or acidic environment, the presence of fat, pus, blood weaken the antiseptic activity. Weakens the hypothyroid and strumagenic effects of lithium preparations.

Pregnancy:

Contraindicated for oral administration during pregnancy.

Iodine belongs to a special kind of useful trace elements necessary for the body. This type of drug, depending on the degree of concentration, consists mainly of an alcoholic solution of iodine, which is able to heal tissues, eliminate fungal and microbial manifestations. Depending on the form and purpose of the iodine drug, this type of remedy can have both external and internal effects on the body. If the drug is in liquid form, it serves as an antiseptic and disinfectant. In tablet form, the remedy has a positive effect on the thyroid gland and on the entire metabolism of the body as a whole.

1. Pharmacological action

Drug group:

Antiseptic drug.

Healing effects of iodine:

• Antimicrobial;
• Annoying;
• Stimulation of thyroxine synthesis.

2. indications for use

The drug is used externally for:

• Comprehensive treatment of various diseases of the skin and mucous membranes.

Iodine is used internally for:

• , tertiary syphilis, endemic goiter, chronic lead and / or mercury poisoning;
• Elimination of chronic inflammatory processes of the respiratory tract;
• Prevention of endemic goiter.

Apply a small amount of 5% or 10% solution to the affected areas several times a day;

0.02 g several times a day.

Application Features:

• According to the instructions, before starting use, any hypersensitivity reactions to the drug should be completely excluded.

4. Side effects

The immune system:

Phenomena of iodism.

5. Contraindications

6. During pregnancy and lactation

Pregnant women and nursing mothers should use the drug contraindicated.

7. Interaction with other drugs

Clinically significant negative interactions of iodine with other drugs

not described

.

8. Overdose

Clinically significant symptoms of iodine overdose

not described

.

9. Release form

• Solution for topical or oral use, 5% - 1 ml, 5 ml, 10 ml, 25 ml or 100 ml bottles. 1 PC. or fl. 4, 5, 6, 8, 10 or 12 pcs;
  2% - 9 or 18 kg.
• Film-coated tablets, 100 or 200 mcg - 48, 60, 96 or 120 pcs.
• Chewable tablets, 100 mcg - 30, 45, 90, 120 or 150 pcs.

10. Storage conditions

• Dry dark place out of reach of children.

Different, depending on the dosage form and the manufacturer, is indicated on the package.

11. Composition

1 ml solution:

• iodine - 50 mg;
• Excipients: potassium iodide, ethanol 95%.

1 tablet:

• iodine (in the form of potassium iodide) - 100 or 200 mcg.

12. Terms of dispensing from pharmacies

The drug is released without a prescription.

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* Instructions for medical use for the drug Iodine is published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST

Last update of the description by the manufacturer 31.07.1998

Filterable List

Active substance:

ATX

Pharmacological groups

Composition and form of release

1 liter of alcohol solution contains iodine 50 g and potassium iodide 20 g; in banks on 5 kg.

1 ml of alcohol solution contains iodine 50 mg; in a box of 10 ampoules of 1 ml.

Characteristic

Transparent liquid of red-brown color with a characteristic smell.

pharmachologic effect

pharmachologic effect- locally irritating, anti-inflammatory, antiseptic.

Forms iodamines and destroys microorganisms, being absorbed, actively affects the metabolism, enhancing the processes of dessimilation; helps lower blood cholesterol levels.

Indications for Iodine

Inflammatory diseases of the skin and mucous membranes, myositis, neuralgia (as a distraction), atherosclerosis, tertiary syphilis.

Contraindications

Hypersensitivity, pulmonary tuberculosis, nephritis, nephrosis, furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, pregnancy.

Side effects

Iodism (runny nose, Quincke's edema, salivation, lacrimation, acne on the skin, etc.)

Dosage and administration

Outwardly, on the damaged areas of the field.

Inside, dissolved in milk, after meals (the dose is set individually), for adults for the prevention of atherosclerosis 1-10 drops 1-2 times a day for 30 days 2-3 times a year; for the treatment of atherosclerosis - 10-12 drops 3 times a day; with tertiary syphilis - 5-50 drops 2-3 times a day. The highest single dose - 20 drops, daily - 60 drops. Children over 5 years old - 3-5 drops 2-3 per day. Children over 5 years of age are prescribed 3-5 drops 2-3 times a day, children under 5 years of age are not prescribed. Higher doses of a 5% solution for adults: single - 20 drops, daily - 60 drops.

Storage conditions of the drug Iodine

In a place protected from light, at a temperature not lower than 0 °C.

Keep out of the reach of children.

Shelf life of the drug Iodine

solution for external use alcohol 5% - 3 years.

Do not use after the expiry date stated on the packaging.

Instructions for medical use

R N001966/01-2002 dated 2010-06-21
Iodine - instructions for medical use - RU No.

Iodine (lodum)

Compound

Obtained from the ashes of seaweed and drilling oil waters. Grayish-black with metallic sheen plates or intergrowths of crystals of a characteristic odor. Volatile at ordinary temperature; when heated, it sublimates, forming violet fumes. Very slightly soluble in water (1:5000), soluble in 10 parts of 95% alcohol, soluble in aqueous solutions of iodides (potassium and sodium). Incompatible with essential oils, ammonia solutions, white sedimentary mercury (explosive mixture is formed).

pharmachologic effect

Has an antimicrobial effect; participating in the synthesis of thyroxine, it affects the function of the thyroid gland, enhances the processes of dissimilation (the breakdown of complex organic substances into simpler ones), and has a beneficial effect on lipid and protein metabolism.

Indications for use

Iodine preparations are used externally and internally; externally used as antiseptic (disinfecting), irritating and distracting agents for inflammatory and other diseases of the skin and mucous membranes, inside - for atherosclerosis, chronic inflammatory processes in the respiratory tract, for tertiary syphilis, hyperthyroidism (thyroid disease), for the prevention and treatment of endemic goiter (thyroid disease due to low iodine content in water), with chronic mercury and lead poisoning.

Mode of application

Externally in the form of a 5% and 10% alcohol solution as an antiseptic (disinfectant), irritant and distraction. Inside, 0.02 g per dose for atherosclerosis, chronic inflammatory processes in the respiratory tract, tertiary syphilis, hyperthyroidism (thyroid disease), endemic goiter, chronic mercury and lead poisoning.

Side effects

Possible phenomena of iodism (non-infectious inflammation of the mucous membranes in the places of iodine release in case of overdose) or individual intolerance to iodine preparations - runny nose, urticaria, etc.

Contraindications

When taken orally: pulmonary tuberculosis, nephritis (inflammation of the kidney), furunculosis (multiple purulent inflammation of the skin), acne, chronic pyoderma (purulent inflammation of the skin), hemorrhagic diathesis (increased bleeding), urticaria, pregnancy, hypersensitivity to iodine.

Release form

Crystalline iodine; alcohol 5% solution in vials and ampoules of 1 ml in a package of 10 pieces.

Storage conditions

In a place protected from light.

Active substance:

iodine

The authors

Links

• Official instructions for the drug Iodine.
• Modern drugs: a complete practical guide. Moscow, 2000. S. A. Kryzhanovsky, M. B. Vititnova.

Attention!
Description of the drug Iodine" on this page is a simplified and supplemented version of the official instructions for use. Before purchasing or using the drug, you should consult a doctor and read the annotation approved by the manufacturer.
Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide on the appointment of the drug, as well as determine the dose and methods of its use.