Terzhinan similar drugs. Cheap analogues of terzhinan
Terzhinan ® is a highly effective combined drug used for the local treatment of vaginitis of various etiologies (fungal, bacterial, mixed, etc.).
The drug contains antibacterial (ternidazole and neomycin), antifungal (nystatin) and hormonal components (prednisolone). Due to the complex composition of the suppository, the inflammatory process is quickly eliminated, and itching and swelling of the mucous membranes are also reduced.
The agent is highly effective against Trichomonas, Corynebacteria, Listeria, Staphylococci, Acinetobacter, Campylobacter, Citrobacter, Enterobacter, Escherichia coli, Haemophilus influenzae, Klebsiella, Morganella, Proteus, Providence, Salmonella, Serrations, Shigella, Yersinia, fungi of the genus Candida, etc.
The drug is intended for local use (intravaginally), therefore, it does not have such restrictions as systemic drugs. However, “assigning” it to yourself is unacceptable. Especially when it comes to the treatment of vaginitis during pregnancy. Therefore, the instructions below are information for reference, and not a self-medication guide.
Terzhinan ® is an antibiotic or not?
Yes, and not even one, but a combination of as many as three antimicrobial agents. Each of them has its own spectrum of bactericidal action, due to which the drug is successfully used in a variety of diseases of the female genital area. And since antibiotics are potent substances, it is unacceptable to use Terzhinanm during pregnancy without a doctor's prescription.
Pharmacological group
The drug is classified as an antiseptic and antimicrobial agent used in gynecology.
The composition of candles Terzhinan ®
Terzhinan ® is available as vaginal tablets. This is a multicomponent preparation for local use - a complex of two antibiotics, an antifungal agent and a hormone-glucocorticosteroid.
Active ingredient matches for Terzhinan:
- Ternidazole- a synthetic antibiotic belonging to the group of nitroimidazoles. It is used only externally, it has a pronounced bactericidal effect against gardnerella, Trichomonas, Giardia and other varieties of bacteria and protozoa.
- Neomycin- a complex antibiotic-aminoglycoside, acting bacteriostatically or (with increasing doses) bactericidal. Staphylo- and streptococci, salmonella, Escherichia coli, shigella are susceptible to it, and the fungal flora is resistant.
- Nystatin- an antifungal agent that is effective against fungi of the genus Candida that cause thrush.
- Prednisolone- dehydrated hormone-glucocorticosteroid, analogue of hydrocortisone. When applied topically, it effectively relieves swelling and inflammation, prevents the development of allergic reactions.
Thanks to this combination, the agent can be used to treat protozoal, bacterial, fungal and mixed vaginitis.
Release form
Unlike many foreign and Russian analogues, Terzhinan ® is available only in the form of vaginal tablets. Each tablet contains active ingredients in the following quantities:
- neomycin - 100 mg;
- nystatin - 100,000 units;
- ternidazole - 200 mg;
- prednisolone - 3 milligrams.
An excipient with clove and geranium oils is used as an auxiliary ingredient. Tablets are packaged in packs of 6 or 10 pieces. Producer - Laboratoires BOUCHARA-RECORDATI ® , France.
Photo of packaging of Tergynan ® tergynan in the form of vaginal tablets
Recipe in Latin
Since new rules for dispensing antibiotics from pharmacies have been introduced since January 2017, Terzhinan ® is available only by prescription. It looks like this:
Rep.: Tab. "Tergynan"
D.t. d. No. 10
S. Daily insert one tablet into the vagina before going to bed, previously moistened with water.
Candles Terzhinan ® - indications for use
A wide range of antimicrobial activity of vaginal tablets allows them to be successfully used for the treatment of:
- inflammation of the vagina caused by Trichomonas;
- fungal vaginitis (candidiasis);
- bacterial vaginitis;
- mixed vaginitis.
Tablets are also used for sanitation before surgery, childbirth, diagnostic manipulations and as a prophylaxis for inflammation after them.
Contrary to popular misconception, Terzhinan ® is not used for cystitis. For the treatment of urinary tract infections, the appointment of systemic drugs is indicated, and the components of this drug practically do not enter the bloodstream.
Terzhinan ® - contraindications for use
Since the antibiotics and the hormone that are part of the drug practically do not have a systemic effect, there are few contraindications to the appointment. It is undesirable to use Terzhinan ® during pregnancy in the first three months.
Menstruation is not a contraindication for treatment: Terzhinan ® does not need to be canceled during menstruation.
Also, the drug is contraindicated in the treatment of acetylsalicylic acid.
Dosage and method of application Terzhinan ®
For the treatment of infections or their prevention, the drug is always used in the same way. Shortly before sleep, after hygiene procedures, one tablet is introduced into the vagina (in the supine position). Moisten the tablet with water immediately before administration.
In severe infections, the drug can be administered twice a day.
Terzhinan ® with gardnerellosis, trichomoniasis and other bacterial infections is usually used for 10 days. Fungal infection of the vagina may require an extension of antibiotic therapy up to 20 days. The prophylactic course is designed for 6 days (for this, there are 2 types of packing of tablets).
Side effects Terzhinan ®
With individual hypersensitivity to the components of the drug, allergic reactions may develop in the form of skin rashes. Such a side effect is extremely rare, but burning in the vagina is noted quite often.
Usually this effect disappears 15-20 minutes after the introduction of the candle. With severe irritation of the mucosa, you need to contact a gynecologist regarding the withdrawal of the drug.
Candles Terzhinan ® during pregnancy
The active components of vaginal tablets act locally, without penetrating into the systemic circulation. Therefore, there is no harmful effect on the fetus. However, given the anatomical proximity of the uterus and vagina, the drug is contraindicated in the first trimester of pregnancy.
Terzhinan ® during breastfeeding
Terzhinan ® is not recommended for breastfeeding. If necessary, the appointment of the drug for the duration of treatment, breastfeeding is stopped.
Compatibility of Terzhinan ® and alcohol
There is no direct prohibition on the use of alcoholic beverages during the course of the drug in the manufacturer's instructions. Ethanol and tablet components do not mix in the blood, since the latter do not get there. But, despite the fact that Terzhinan ® suppositories and alcohol do not directly interact, treatment should not be combined with the intake of alcoholic beverages.
Blood flow to the tissues due to the vasodilating effect of alcohol can increase the sensitivity of the mucosa and, accordingly, burning. It is also possible to increase the symptoms of candidiasis.
Analogues are cheaper than Terzhinan ® and others
These tablets do not have a completely identical substitute in structure. Polygynax ® containing nystatin with neomycin can be considered closest to the original. This analogue of Terzhinan ® is intended for women with the same diseases, but it has some features and is more expensive. According to the indications, you can also use imported drugs in the form of suppositories and tablets Neo-Penotran ® , Macmiror ® , Fluomizin ® and.
The average price for a package of 6 vaginal tablets is 400 rubles, for 10 - about 500, and imported substitutes are even more expensive. In this regard, patients are often interested in whether there are Russian analogues of Terzhinan ® at a more affordable cost. By agreement with the gynecologist, instead of the French remedy, you can buy domestic candles Hexicon ® (10 pieces for 280 rubles) or tableted Clotrimazole ® (6 pieces cost only 20 rubles). However, Clotrimazole ® is not an alternative to Terzhinan ® and can only be used for fungal vaginitis (thrush).
Terzhinan ® or Neo-Penotran ® , which is better?
In terms of cost, the French drug is more profitable: 14 German-made vaginal suppositories will cost about 800 rubles. Indications for use for both drugs are practically the same, and the composition is completely different. The active ingredients of Penotran are the antibiotic metronidazole and the fungicide miconazole.
Which is better, Macmirror ® or Terzhinan ®?
Italian suppositories called Macmirror-Complex ® consist of nystatin with nifuratel. Accordingly, they are effective in candidiasis, bacterial and fungal vaginitis. The difference between the drugs lies in the contraindications (nursing and pregnant Macmirror ® is not allowed), the absence of a burning sensation characteristic of Terzhinan ®. An Italian remedy costs about 800 rubles for a pack of 8 candles.
Terzhinan ® or Fluomizin ® , which is better?
The drugs belong to different classes: the first is an antibiotic, and the second is an antiseptic. However, its active substance (dequalinium chloride) is active against the same inflammatory pathogens. Accordingly, these tablets are prescribed for the same indications, but if Terzhinan ® does not lose its effectiveness during menstruation, then treatment with Fluomizin ® must be interrupted. Another difference is the price: a drug from Switzerland will cost 730 rubles per course.
What is better, Hexicon ® or Terzhinan ® ?
The domestic drug in the form of suppositories or tablets costs a little less than the French one (about 280 rubles for 10 pieces). Its active ingredient is the antiseptic chlorhexidine, which has a similar spectrum of antimicrobial action. The indications are the same, during pregnancy and breastfeeding is allowed, but requires twice daily administration for at least a week. Therefore, saving in this way will not work.
In addition, patients often complain about the appearance of bloody discharge from Hexicon ® suppositories, especially during pregnancy. Slight staining in pinkish or brown color is considered the norm, and more intense requires cancellation. In this regard, the question of which is better, Hexicon ® suppositories or Terzhinan ® , it is advisable to discuss with the gynecologist in advance.
What is better, Polygynax ® or Terzhinan ® ?
Polygynax ® , as already mentioned, is the closest analogue. It contains the same nystatin and neomycin, as well as polymyxin B ® . There is no hormonal component in it, respectively, and the anti-inflammatory effect is less, and the price is higher - almost 700 rubles for a course of therapy (12 suppositories). Contraindicated in pregnant women in the first 3 months and lactating.
What is better, Terzhinan ® or Klion-D ® ?
Hungarian-made vaginal tablets at a price of about 370 rubles per pack of 10 pcs. the composition is the same as that of Neo-Penotran ® . If there are no contraindications (pregnancy, 1st trimester or lactation), you can use an analogue.
In this article, you can read the instructions for using the drug Terzhinan. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Terzhinan in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Terzhinan in the presence of existing structural analogues. Use for the treatment of thrush (candidiasis), vaginitis, vaginosis, trichomoniasis and other infectious diseases of the female genital area, including during pregnancy and lactation. Menstruation and discharge while taking the drug. Can I have sex while taking medication.
Terzhinan- combined preparation for local use in gynecology. The action of the drug is due to the properties of its constituent components.
The composition and action of the components of the drug
Ternidazole - an imidazole derivative - has a trichomonacid effect, is also active against anaerobic bacteria, in particular Gardnerella spp.
Neomycin sulfate is a broad-spectrum antibiotic from the group of aminoglycosides.
Nystatin is an antifungal antibiotic from the group of polyenes, highly active against fungi of the genus Candida.
Prednisolone is a glucocorticoid that has a pronounced anti-inflammatory effect.
The composition of the excipient ensures the integrity of the vaginal mucosa and the constancy of pH.
Pharmacokinetics
Studies of the pharmacokinetics of the drug Terzhinan were not conducted due to low systemic absorption.
Indications
Treatment of vaginitis caused by microorganisms sensitive to the drug:
- bacterial vaginosis;
- bacterial vaginitis caused by banal pyogenic or conditionally pathogenic rod microflora;
- trichomoniasis of the vagina;
- vaginitis caused by fungi of the genus Candida;
- mixed vaginitis.
Prevention of vaginitis:
- before gynecological operations;
- before childbirth or abortion;
- before and after the installation of the IUD;
- before and after diathermocoagulation of the cervix;
- before hysterography.
Release forms
Vaginal tablets, in packs of 6 and 10 tablets (sometimes erroneously called vaginal suppositories).
Instructions for use and dosing regimen
Assign 1 vaginal tablet (candle) per day before bedtime. The average duration of the course of therapy is 10 days; in case of confirmed mycosis, it can be increased up to 20 days. Do not stop treatment during menstruation.
Before insertion into the vagina, the tablet should be held in water for 20-30 seconds.
Side effect
- burning sensation;
- local irritation (especially at the beginning of therapy);
- allergic reactions.
Allocations when using the drug are not typical, you should contact your doctor for advice.
Contraindications
- hypersensitivity to the components of the drug.
Use during pregnancy and lactation
It is possible to use Terzhinan during pregnancy and lactation (breastfeeding) according to indications.
special instructions
It is necessary to conduct simultaneous treatment of the sexual partner because of the risk of re-infection. Also, at the time of treatment with Terzhinan, sexual contacts (sex) with a partner should be excluded.
drug interaction
No clinically significant drug interactions of Terzhinan with other drugs have been identified.
Analogues of the drug Terzhinan
Terzhinan has no structural analogues for the active substance.
In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.
Terzhinan is excellent for vaginitis. In general, vaginitis is a terrible thing, I would not wish it on anyone. It is impossible to work or sleep with him. At first, I myself read on the Internet how you can be treated, but there are so many things, it is not clear what will really help. When my appointment with the doctor came up, I already had severe swelling. Gynecologist... Terzhinan is excellent for vaginitis. In general, vaginitis is a terrible thing, I would not wish it on anyone. It is impossible to work or sleep with him. At first, I myself read on the Internet how you can be treated, but there are so many things, it is not clear what will really help. When my appointment with the doctor came up, I already had severe swelling. The gynecologist prescribed Terzhinan and said to start on the same day. He has a course of 10 days. And he really saved me from vaginitis in these 10 days. Substances are not absorbed into the blood, so there are no restrictions on interaction with other drugs + no negative effect on internal organs. For the price, it is normal, as it seemed to me, it costs less than 600 r.
Terzhinan was prescribed by a gynecologist, I had vaginitis. I took it hard, even cried a couple of times, it was so bad. These pills are the only thing that saved me! They are really very effective, they alleviated the symptoms already in 2 applications. I thought that I would stay in this state for another 5 days, but here it is so fast ... Terzhinan was prescribed by a gynecologist, I had vaginitis. I took it hard, even cried a couple of times, it was so bad. These pills are the only thing that saved me! They are really very effective, they alleviated the symptoms already in 2 applications. I thought that I would stay in this state for another 5 days, but here such a quick effect. Despite the powerful composition, the drug is practically not absorbed, so other organs and the general condition do not suffer.
Manyuta
I have a feeling that half of the terzhinan candle comes out unchanged. now I understand why doctors praise gelatin capsules - while I was being treated with ecofemin, I didn’t even notice how these capsules dissolved. and these pills like terzhinan are the last century.
The only thing I didn't like about terzhinan is that it has a strong burning sensation. But it helps well. True, it also kills its microflora to zero, then it was restored for another week with ecofemin. On the other hand, there is a guarantee that there is no infection left.
no matter how strong it is, so that there are no problems later, it must be combined with ecofemin or some other probiotics. then the treatment is really effective
After terzhinan, the desire to be treated with candles disappeared completely. This is some kind of horror - such a burning sensation! Previously, she was treated with other candles, the same thing happened, but after metrogila, plus for some reason there is no burning sensation. What is added to candles?
Not my remedy. Even a penny metrogil plus was better tolerated and helped no worse, although it would seem that this is a gel, but here are candles. I don't understand why I paid so much money.
I have had chronic candidiasis for many years. When the doctor prescribed terzhinan with fluconazole. Now, during the period of relapse (before 2-3 times a year, now less often) I use the same purpose. Just like in an anatomy, the first two or three days, burning and itching, then the sensations pass, I am treated to the end and everything is getting better. Now I clean the body with dietary supplements, which to get rid of it completely.
I took a course of 10 days, there was vaginosis, there was absolutely no burning and itching! After treatment, I re-tested - everything was normal! So this product helped me a lot! I took a course of 10 days, there was vaginosis, there was absolutely no burning and itching!
After treatment, I re-tested - everything was normal! So this product helped me a lot!
Tell me what to do. For two days I have been using these vaginal pills, a strong burning sensation, itching, a strong allergy has begun, my whole body itches, even allergy pills only help for a few hours. Holidays, March 8th and all that. Gynecologists are all resting, there is no one to even ask.
I was prescribed Terzhinan suppositories for trichomonas vaginitis. Of course the pain is still the same. The treatment was very serious. In addition to Terzhinan, antibiotics and a bunch of vitamins and preparations for the stomach and liver are also taken orally. It is necessary. Terzhinan is a powerful antibiotic and can cause a number of side effects, by the way, I felt it myself. I also went to the gynecologist for... I was prescribed Terzhinan suppositories for trichomonas vaginitis. Of course the pain is still the same. The treatment was very serious. In addition to Terzhinan, antibiotics and a bunch of vitamins and preparations for the stomach and liver are also taken orally. It is necessary. Terzhinan is a powerful antibiotic and can cause a number of side effects, by the way, I felt it myself. I also went to the gynecologist for douching. The treatment went very well, after that several years have passed, everything is in order.
Girls, it is very important that the treatment regimen is correct and the drugs are chosen correctly. It all depends on your doctor.
Terzhinan is produced in vaginal tablets with active ingredients - ternidazole, nystatin, prednisolone and neomycin. The cost of the medication is quite high, so doctors very often prescribe Terzhinan analogues in therapy.
A medication is prescribed for:
- trichomoniasis;
- vaginosis of bacterial etiology;
- nonspecific vaginitis at the stage of relapse;
- candidiasis;
- vaginitis of a mixed type, which are caused by anaerobic microorganisms - gardnerella, a yeast-like fungus.
Tablets can also be prescribed to prevent the development of infection during childbirth or abortion. Terzhinan is often used before the installation of contraceptive intrauterine devices, as well as before the behavior of a diagnostic intrauterine examination with vaginal sensors. During pregnancy and lactation, the medication can be used. Do not use Terzhinan in the treatment of allergies to the drug.
Terzhinan tablets are used intravaginally. They must be inserted into the vagina once a day at bedtime. Before inserting a tablet, it is recommended to soak it for 15-30 seconds in boiled water cooled to room temperature, and then insert deeply into the vagina. The average duration of therapy is 7-10 days. When treating mycosis, the duration of treatment can be increased to 15-20 days. Terzhinan can also be used during menstruation.
Terzhinan practically does not cause negative effects, sometimes patients notice allergic reactions, which are manifested by itching, burning, discomfort at the injection site.
Prices for Terzhinan and its analogues
Prices for analogues of the Terzhinan medication are quite high, only Russian-made medicines have a more affordable cost.
Popular candle substitutes Terzhinan
The most popular substitutes for Terzhinan are medications that are not structural analogues, but have the same therapeutic direction and effect.
Flucostat
The Russian drug Flucostat is produced in capsules for oral administration and in a solution for intravenous injections based on fluconazole.
Pilyule_ana-097 Flucostat is prescribed for lesions of the reproductive system caused by:
- Trichomonas;
- cryptococci and candida;
- onychomycosis and mycosis;
- we deprive the pityriasis type.
In addition, the drug is prescribed to prevent the development of infection in patients with HIV and AIDS, as well as in cytostatic, chemotherapy and radiation therapy.
Flucostat is not used in patients with an allergy to the medicinal composition, with lactose intolerance and lactation. It is prescribed with caution for pathologies of the kidneys and liver, for alcoholism in the chronic stage, during pregnancy.
On the first day of therapy for candidiasis and other fungi, 400 mg should be taken once, from the second day the dosage is halved (200 mg). You need to take the medicine for 7-10 days.
To prevent the development of recurrent meningitis in patients with HIV and AIDS - 200 mg once a day for a long time period. With intravenous administration, the patient also receives an initial dosage of 400 mg, on subsequent days, 200 mg.
Among the adverse reactions are the following:
- allergies - urticaria, pruritus, redness of the skin and rash;
- nervous system - headache and dizziness, increased fatigue;
- digestive organs - dyspepsia, abdominal and epigastric pain, diarrhea and vomiting.
Neotrizol
These are tablets for the treatment of vaginal infections of various etiologies. The medication is combined, and contains antibacterial components (neomycin and ornidazole), antifungal (miconazole) and glucocorticoid prednisolone.
The drug Neotrizol is prescribed in gynecology for:
- vaginosis and vaginitis;
- candidiasis;
- anaerobic infection;
- trichomoniasis and gardnerellosis.
Also, the medication is prescribed for the prevention of infections during the period of surgical treatment of gynecological organs and cleaning the vagina from infections before childbirth, abortion, and also on the eve of intrauterine diagnosis.
You can not use Neotrizol for allergies to the constituent components of the drug, as well as in pediatrics and lactation. With high caution, a medication is prescribed for such pathologies:
- colitis and ulcerative lesions of the digestive organs;
- osteoporosis;
- diabetes;
- tuberculosis;
- epilepsy and cardiac diseases;
- myopathy, hypertension and glaucoma;
- after a heart attack and with severe mental disorders.
1 tablet should be inserted into the vagina before going to bed. After the introduction of the tablet, you must be in a horizontal position for up to 20 minutes. At the time of menstrual flow, therapy should not be interrupted. The number of procedures for the introduction of tablets is 8. If the symptoms of the infection have not disappeared in 8 days, then another eight-day course must be completed.
The reaction of the body to the medication appears infrequently and is expressed by burning and itching at the injection site, as well as skin rash and urticaria, vasospasm in the head and headache. Very rarely, increased drowsiness, edema in the peripheral regions, tremor of the limb and unreasonable irritability are noted.
cervugid
Cervugid is a substitute for Terzhinan with active ingredients: chloramphenicol, metronidazole, nystatin and hydrocortisone acetate. The components are able to cleanse wounds and necrotic tissues from the accumulation of pus in them, and also have the ability to block the development of microorganisms and the spread of infection. A medication is prescribed for such diseases:
- pathologies provoked by anaerobic and aerobic gram-negative or gram-positive microorganisms - clostridia, shigella, streptococci, staphylococci;
- trichomoniasis, mycoplasmosis and chlamydia;
- candidiasis;
- cervicitis.
Also, pessaries are placed for the prevention and treatment of infections after treatment with immunosuppressants or corticosteroid hormonal medications, after radiation and chemotherapy, as well as before surgical treatment of gynecological organs or before intravaginal examination.
Do not prescribe medicine for:
- allergies to the ingredients of the drug;
- pathologies in the hemostasis system;
- dysfunction of the liver and kidneys;
- pregnancy, breastfeeding and pediatrics (up to 14 years).
Assign 1 pessary per day on the eve of sleep for 7 days. For cystitis aggravated by ulcers and scarring, 1 pessary is prescribed twice a day for 7 days. If there is a severe infectious pathology, then in addition to topical application, systemic use of antibacterial medications is necessary.
The drug provokes the development of such side pathologies:
- erythema, skin reactions, burning at the injection site;
- change in work in the digestive tract - dyspepsia, epigastric and abdominal pain;
- neuropathy and encephalopathy, dizziness and headache;
- mental deviations and hallucinations;
- disturbances in the work of hemostasis, the function of the liver, gallbladder and kidneys;
- staining urine in a red tint.
Analogues for men
For men, the pharmacological market offers antibacterial medicines for local and systemic use, which are therapeutic analogues of Terzhinan.
Pimafucin
Pimafucin is produced in cream, in suppositories and in tablets, with the main component natamycin. Pimafucin is used for:
- long-term therapy with cytostatics or glucocorticosteroid drugs;
- fungal infection of the digestive system;
- vulvovaginitis of candidal origin;
- damage to the skin and nail plates by a fungus.
Quite often, Pimafucin is part of the combination therapy of various fungal infections.
Do not prescribe a medication for allergies to the ingredients of the drug. During pregnancy, in childhood from 7 years of age and during breastfeeding, there are no separate restrictions on the use.
When treating candidiasis in the digestive tract, you need to take 1 tablet four times a day for a week. For children, the dosage is halved.
In the treatment of candidiasis of the nail plate, it is necessary to apply a cream on it and take pills. The frequency of the procedure per day of cream and tablets is 4 procedures. The duration of admission is 2-3 months. The cream is used to treat dermatosis - 1-4 application procedures for 15-20 days.
At the initial stage of therapy, the patient may experience digestive disorders - diarrhea, flatulence, vomiting, gastralgia and nausea. Also, the following allergy symptoms are often noted:
- redness and burning at the site of application of the medication;
- severe itching of the skin and hives;
- dizziness or headache.
clotrimazole
Clotrimazole is manufactured in the form of vaginal tablets and suppositories, spray, paste, cream, ointment and solution for external use. The active ingredient is clotrimazole. The drug is a substitute for Terzhinan and has an antifungal effect on gram-positive and gram-negative bacteria of aerobic and anaerobic types. A medication is prescribed for such diseases:
- onychomycosis, versicolor and athlete's foot;
- mycosis of folds on the skin and erythrasma;
- candidiasis and dermatophytes;
- pyoderma, urogenital infections;
- trichomoniasis, candidiasis;
- vulvovaginitis;
It is also used for the rehabilitation of the birth canal immediately before childbirth.
You can not use the medicine for the following reasons:
- hypersensitivity to the components of the drug;
- 1 trimester of pregnancy;
- at the time of menstruation;
- in pediatrics up to 16 years and lactation.
The drug must be applied to the foci of fungal infection 1-3 times a day. Medicine for external use (ointment, paste, cream, solution, spray) is applied in an even thin layer and carefully rubbed into the affected area. The skin at the site of application of the medicine should be washed and dried.
Adverse reactions of the body are quite rare and are most often expressed by skin allergies - rash, itching and urticaria, as well as a burning sensation, tingling at the site of application of the drug to the skin. Also, women note a burning sensation inside the vagina after the introduction of vaginal tablets and suppositories or vaginal gel.
The cheapest similar products for women
Terzhinan is in the high price segment, therefore, for many patients, the course of therapy with Terzhinan is very expensive. There are analogues of Terzhinan, which are several times cheaper than the original.
Meratin Combi
Meratin Kombi is an antibacterial and antiseptic medication that is effectively used in gynecology. The following microorganisms are sensitive to the drug:
- Trichomonas and Giardia;
- amoeba and anaerobic microorganisms - clostridia, cocci, bacteroids.
The drug destroys the membranes of microbes, which leads to their death. Prescribe a medicine for the treatment of such pathologies:
- vaginitis and vaginosis of bacterial etiology;
- trichomoniasis and candidiasis.
Also, the drug is used for prophylaxis before surgical treatment of gynecological diseases, the procedure for establishing intrauterine devices and vaginal diagnostics, as well as for lining the birth canal on the eve of childbirth or before an abortion procedure.
Do not prescribe medication:
- if you are allergic to the components in the medicine;
- women in the 1st trimester of pregnancy.
With a restriction, Meratin Combi suppositories for women in the 2nd and 3rd trimesters of pregnancy and at the time of breastfeeding can be used in therapy.
It is necessary to introduce a tablet into the vagina with the help of an applicator 1 time per day before going to bed, after soaking it for several seconds in warm water. After its introduction, you need to lie down for 12-20 minutes. At the time of menstrual flow, you should not interrupt treatment. The standard drug course lasts 10 days.
Very rarely, women report side effects from the use of the drug, but the manufacturer noted the following negative effects of the medication:
- skin allergy;
- discomfort and burning at the injection site;
- the formation of intravaginal erosions;
- atrophy of the vaginal mucosa;
- slowing down wound healing.
Polygynax
Polygynax vaginal capsules are produced on the basis of active ingredients - nystatin, neomycin and polymyxin B. Polygynax is used to treat such infectious and inflammatory pathologies:
- vulvovaginitis and cervicovaginitis;
- fungal vaginitis;
- vaginitis caused by mixed infections.
Also, the medication Polygynax is used to prevent the development of infection:
- during surgical treatment;
- after intrauterine diagnosis;
- during the procedure for installing an intrauterine device;
- to cleanse the birth canal before childbirth;
- before the abortion procedure.
It is forbidden to prescribe Polygynax to women in the 1st trimester of pregnancy and in case of hypersensitivity to the drug. With high caution prescribed in the 2nd and 3rd trimester, as well as women in the period of HB. When using a medication in the treatment, it is necessary to focus on the fact that the medication reduces or completely blocks the effect of local contraceptives, and there is also a high risk of damage to the condom. Treatment with Polygynax increases the risk of unwanted pregnancy.
Polygynax is used by the method of intravaginal administration of a capsule, which is injected deep into the vagina before going to bed. After the introduction of the vaginal capsule (1 pc.), you need to lie down in a horizontal position for 10-15 minutes. Therapy can last 10-12 days. For the prevention of Polygynax, you can take 5-6 days.
When using capsules, the development of side effects is possible:
- itching and burning;
- hyperemia of the vaginal mucosa;
- development of allergic erythema.
Symptoms of allergic reactions on the skin may also appear - urticaria, reddening of the areas and itching of the skin.
Thanks
The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!
Terzhinan is a combination drug for topical use in gynecological practice. Terzhinan vaginal tablets are well tolerated, without discomfort and without causing discomfort during use. The drug has a wide spectrum of action, destroying various pathogenic bacteria, fungi and protozoa present in the woman's vagina, and therefore Terzhinan is an excellent remedy for the treatment of colpitis (vaginitis). Terzhinan tablets quickly stop itching and discomfort in vaginitis, and an additional advantage is their ease of use.In addition, Terzhinan is used to prevent vaginitis before gynecological surgical interventions (for example, "cauterization of cervical erosion", etc.), childbirth, abortion, installation of an intrauterine device and other manipulations carried out through the vagina.
Forms of release, composition and names of Terzhinan
At present, the drug Terzhinan is produced in a single dosage form - this tablets for insertion into the vagina. The tablets are oblong, flat, cream colored and marked with the letter "T" on both sides. Available in packs of 6 or 10 pieces. Since drugs intended for insertion into the vagina are most often produced in the form of suppositories, Terzhinan may be mistakenly called candles Terzhinan. However, this is not correct, since the drug is available in the form of tablets. But it should be borne in mind that when someone says "Terzhinan candles", he means exactly the pills.
In addition, the drug is often called "Terzhinan 10" or "Terzhinan 6", where the number after the commercial name indicates the number of tablets in the package. Such names are not official, but are used by doctors, pharmacists and patients very often, and therefore are considered generally accepted. Therefore, using such common clichés, you can not worry that a person will be misunderstood.
The composition of Terzhinan tablets as active ingredients includes the following substances:
- Ternidazole - 200 mg;
- Neomycin sulfate - 100 mg (65,000 IU);
- Nystatin - 100,000 IU;
- Prednisolone sodium metasulfobenzoate - 4.7 mg, which corresponds to 3 mg of pure prednisolone;
- Geranium and clove oil - 1.2 g.
Terzhinan tablets contain the following substances as auxiliary components:
- Wheat starch;
- Colloidal silicon dioxide anhydrous;
- Sodium starch glycolate (type A);
- magnesium stearate;
- lactose monohydrate;
- Purified water (distilled, deionized, sterile).
Therapeutic effects of the drug
Terzhinan tablets are injected into the vagina, where they have the following therapeutic effects: - Antibacterial action, which consists in the destruction of pathogenic and opportunistic bacteria (staphylococci, streptococci, gardnerella, etc.), provoking infectious and inflammatory processes in the vagina (colpitis);
- Anti-inflammatory effect, which consists in the rapid suppression of the inflammatory process in the vagina, provoked by any reason;
- Antifungal action, consists in the destruction of various fungi and the elimination of thrush;
- Antiprotozoal action consists in the destruction of pathogenic protozoa, such as chlamydia, Trichomonas, etc.
Ternidazole is an antifungal agent from the imidazole group, which stops the synthesis of lipids necessary for the construction of fungal cell walls. As a result, the cell membrane of fungi loses its properties, its configuration is disturbed, and it ceases to perform the necessary functions, as a result of which the microorganism dies. In addition, Ternidazole has a detrimental effect on trichomonas and gardnerella.
Neomycin sulfate is a broad-spectrum antibiotic of the aminoglycoside group, which has a detrimental effect on staphylococci (Staphylococcus spp.), Escherichia coli (Escherichia coli), Shigella (Shigella spp.) and Proteus spp., which are often the causative agents of nonspecific colpitis, vulvovaginitis or bacterial vaginosis. Microbial resistance to neomycin develops very slowly and rarely, so it is effective in almost all cases. In relation to various varieties of streptococci, neomycin is ineffective.
Nystatin is an antifungal antibiotic of the polyene group, which effectively destroys fungi of the genus Candida and, accordingly, cures thrush. Nystatin has been used for a long time and successfully, but despite this fact, the resistance of fungi to the antibiotic is practically absent.
Prednisolone is a glucocorticoid hormone derived from hydrocortisone and has a powerful anti-inflammatory effect. Prednisolone suppresses any inflammatory reaction, regardless of the nature of the causes that provoked it, therefore, in combination with antifungal, antibacterial and antiprotozoal agents, it quickly eliminates colpitis and vulvovaginitis of any etiology.
In addition, prednisolone has antiallergic and antiexudative effects. Therefore, under the influence of this component, women do not develop allergic reactions and edema stops.
Terzhinan - indications for use
Terzhinan tablets are used for the treatment and prevention of infectious and inflammatory diseases of the vagina (vaginitis) caused by microorganisms sensitive to the action of the drug.So, Terzhinan tablets are shown for the treatment of vaginitis in the following cases:
- Bacterial vaginitis caused by Staphylococcus aureus, Proteus, Shigella, Escherichia coli, or Trichomonas;
- Complex therapy of colpitis provoked by chlamydia;
- Fungal vaginitis, provoked by yeast-like fungi Candida;
- Vaginitis caused by mixed flora, that is, simultaneously bacteria, fungi, trichomonas or gardnerella in various combinations.
- Before planned gynecological operations;
- Before childbirth or abortion;
- Before and after the installation of the intrauterine device;
- Before and after diathermocoagulation ("cauterization"), laser or chemical treatment of cervical erosion;
- Before hysterography or hysterosalpingography;
- Before any medical manipulations related to the introduction of any objects, instruments or doctor's hands into the vagina.
Terzhinan - instructions for use
General provisions
Terzhinan tablets should be inserted into the vagina one piece at a time. Do not use two or more tablets for one injection, as this can lead to the absorption of too high a dosage of prednisolone into the bloodstream and, accordingly, the development of systemic side effects of glucocorticoid hormones.For treatment and prevention, it is necessary to administer one tablet once a day for the period of time prescribed by the doctor.
The tablet must be removed from the package immediately before use and inserted into the vagina as soon as possible, otherwise it may begin to soften and melt. A soft pill is much more difficult to properly insert into the vagina. To remove Terzhinan from the package, the foil must be torn along the length of the tablet or cut with scissors.
Terzhinan should always be administered with freshly washed hands with soap or with sterile surgical gloves. Do not handle with dirty hands. Moreover, hands that have not been washed for an hour are considered dirty, even if the woman was at home or in a relatively clean room.
Before administering a Terzhinan tablet, it is recommended to wash your hands with soap - solid or liquid, and not use various commercially available lotions, waters, foaming formulations, emulsions and other products designed to remove contaminants from the skin of the hands. The only product that can be used to wash and sanitize hands before inserting pills into the vagina is antiseptic or antibacterial liquids.
In addition, it is necessary to avoid touching the anus with your fingers during the insertion of the tablet into the vagina, as this can lead to additional infection.
If part of the course of treatment with Terzhinan tablets falls on the period of menstrual bleeding, then it should not be interrupted. In other words, tablets must continue to be inserted into the vagina during menstrual bleeding, since their effectiveness is not reduced. But during menstruation, you should especially carefully observe the rules of hygiene when administering tablets.
If a woman has been diagnosed with vaginitis, then it is recommended to undergo a course of therapy not only for her, but also for her sexual partner. This recommendation should be considered mandatory in the case of trichomoniasis. In other situations, the treatment of the sexual partner is advisory.
During the entire period of therapy, it is necessary to refrain from sexual intercourse and not to use lubricants, lubricants, gels, ointments and any other means intended for insertion into the vagina, since they can completely neutralize the therapeutic effect of Terzhinan.
How to administer Terzhinan vaginally?
It is optimal to administer the drug in the evening just before going to bed, however, if for some reason this is not possible, then Terzhinan can be used at any time of the day. The main thing to follow the rule is to enter one candle per day.First, before the introduction of the tablet, you should wash the external genital organs and the perineum, including the anus, with warm water and soap. It is not recommended to use any gels or other hygiene products for washing. Then you need to wash your hands also with soap or treat them with an antiseptic liquid. If for some reason it is impossible to wash your hands, then you should put on sterile surgical gloves, which are sold in pharmacies.
After that, the tablet is removed from the package and dipped in a cup of clean, cool boiled water for 20-30 seconds so that the top layer dissolves a little, and the drug begins to act immediately.
The tablet is removed from the cup and taken in a comfortable position for administration. At this point, you should dwell in more detail, since the instructions for use indicate that you need to administer the tablet in the supine position. However, it is not convenient for all women to administer the drug while lying on their backs, since the tablet is quite small and difficult to push into the collapsed vagina. Therefore, doctors recommend administering the drug in the position in which it is most convenient to do this, but in the immediate vicinity of the bed or sofa, on which it will be necessary to lie down a little after the manipulation.
The most convenient for the introduction of Terzhinan tablets are the following positions:
1.
Squatting with knees wide apart.
2.
Standing, with one leg raised and resting on a chair or other elevation.
3.
Lying on your back with knees and hips bent and legs drawn to the stomach.
Having chosen the optimal position, it is necessary with the fingers of a non-working hand (left for right-handers and right for left-handers) to gently part the labia to the sides and expose the entrance to the vagina. Then, with the index finger of the working hand, push the tablet deeply forward until it stops advancing.
After that, the finger must be removed from the vagina and, making a minimum of movements, lie on your back on a bed or sofa. In this position, you should lie down for 10-20 minutes so that the tablet completely dissolves and the active substances begin to be absorbed into the cells of the vaginal mucosa.
After 10 - 20 minutes, you can get up, put on your underpants, putting a panty liner on them, as discharge may appear, and go about your business.
How long does the treatment take?
For treatment and prevention, it is necessary to administer one tablet of Terzhinan every day during the entire course of therapy. Treatment of various vaginitis usually lasts 10 days, but with confirmed candidiasis, the course of therapy is extended to 20 days. Prophylactic use of Terzhinan tablets is carried out within 6 days.Application of Terzhinan during the day
The use of Terzhinan during the day is quite possible if a woman has the conditions for the correct introduction of tablets into the vagina. The instructions for use of the drug indicate that it is recommended to use the tablets in the evening, before going to bed. This recommendation is due to the fact that such a tactic will ensure a long-term, for several hours, the presence of active components in the vagina, from where they will flow in a minimal amount due to the horizontal position of the body. However, this recommendation is not strict and can be easily ignored.That is, Terzhinan tablets can be inserted into the vagina during the day, in the morning, and in the early evening, etc. But in this case, after the manipulation, you should definitely lie down for 10-20 minutes on your back on a flat surface, and only after that get up or sit down. Also, when Terzhinan tablets are administered during the daytime, panty liners should be used, since a small part of the melted medicine will flow out under the influence of gravity. In addition, it is morally and psychologically necessary to tune in to the fact that with the daily administration of Terzhinan tablets, it is necessary to increase the duration of therapy by about 1/4 - 1/3 in order to compensate for the leaked volume of the drug. That is, if a 10-day course of Terzhinan is prescribed, then with the introduction of tablets during the day, it should be increased to 12-13 days, etc.
After Terzhinan
If the tablets were inserted into the vagina in the evening, before going to bed, then in the morning the woman may have yellow, copious mucous discharge, sometimes colored lemon-colored, for 1 to 3 hours. This is normal and represents the release of excess and remnants of the tablet from the vagina. The discharge will stop as soon as the woman completes the course of therapy or prophylaxis with Terzhinan tablets. If the tablets are used during the day, then such discharge may appear about an hour after administration and continue for another 2 to 4 hours.In some women, Terzhinan causes severe itching, which they mistake for a recurrence of thrush. However, this drug is not able to provoke thrush, since it contains components that have a detrimental effect on fungi of the genus Candida, which are the causative agents of the disease. Therefore, the cause of itching and discharge during the use of Terzhinan are other factors.
So, normally, in the first days of treatment, tablets can really cause itching, which gradually decreases, and completely disappears by the end of therapy. If the itching does not decrease and does not disappear, then most likely this is a manifestation of an allergic reaction, which requires the abolition of Terzhinan.
After using Terzhinan, many doctors recommend putting down a course of any suppositories containing lactobacilli and bifidobacteria for the speedy restoration of microflora. Most often, candles Vagisan, Atsilakt, Bifidumbacterin and others are used for this purpose. Separately, it should be noted the drug Vagilak, which is a capsule for oral administration containing strains of lactobacilli that penetrate well from the intestine into the vagina and take root well in it. Also, to restore the microflora of the vagina after treatment with Terzhinan, you can take conventional probiotics, since the normalization of the intestinal microflora will accelerate this process in the genitals.
Influence on the ability to control mechanisms
Terzhinan tablets do not affect the ability to control mechanisms, so women using the drug can engage in any type of activity that requires a high speed of reactions and concentration.Overdose
An overdose of Terzhinan is impossible due to the slight absorption of the active components into the systemic circulation.Interaction with other drugs
Terzhinan tablets do not significantly interact with any other drugs, so they can be used in combination with any drugs.Treatment with Terzhinan - effective regimens
Many women are not completely satisfied with the result of treatment with Terzhinan, because they may have some discomfort or discomfort after the end of therapy, or they may occur directly in the process of using the tablets. To stop these unpleasant sensations, among which the most common are itching, burning, discharge, pain at the end of urination and pain during sexual intercourse, Terzhinan is used in combination with other drugs. So, for the relief of itching and the prevention of trovorous discharge similar to thrush that occurs in the first days of Terzhinan's use, it is recommended to put down Pimafucin suppositories for 3-5 days before that. This tactic makes the use of Terzhinan comfortable and almost invisible.
To stop the discomfort that occurs after treatment with Terzhinan, which in most cases are due to the absence of normal vaginal microflora, since the pathological one was destroyed during therapy, and the normal one has not yet had time to settle, microsyringes with Tantum Rosa antiseptic or probiotic preparations are used. Among probiotics, the most effective are Vagisan, Vagilak, Acipol and others.
Separately, it is worth noting Vagilak, which is a capsule for oral administration, which is very convenient, since you do not need to insert something into the vagina again. These capsules contain lactobacilli that can penetrate the vagina through the intestinal wall, quickly populate it and take root, due to which Vagilak quickly restores normal microflora.
Application for thrush
With thrush, Terzhinan is an effective treatment, since it contains two active components that have a detrimental effect on different types of fungi. However, in order to achieve a stable remission and stop recurrences of thrush for a long period of time, Terzhinan tablets should be used for 20 days in case of thrush. If not only fungi of the genus Candida, but also mycelium are found in a vaginal smear, then for effective treatment, antifungal drugs containing fluconazole (Diflucan, Diflazol, etc.) should be taken orally in combination with Terzhinan tablets. Moreover, antifungal drugs should be taken during the entire course of therapy with Terzhinan, that is, for 20 days. The regimen for taking drugs can be twofold: 1. Take any drug fluconazole 50 mg 1 time per day daily.
2. Take any drug fluconazole 150 mg 1 time per day every three days.
If this treatment regimen is followed, thrush is completely cured and its relapses do not bother the woman for several years.
Terzhinan during pregnancy and breastfeeding
During the entire first trimester of pregnancy (from the beginning to the 12th week of gestation inclusive), Terzhinan tablets cannot be used, since the active ingredients can penetrate into the uterus and have a negative effect on the fetus. However, if the woman's condition is not satisfactory, which can also adversely affect the course of pregnancy, then Terzhinan tablets are also used in the first trimester.From the second trimester of pregnancy and up to childbirth, Terzhinan can be used without fear, since during these periods of bearing a child, the drug is no longer able to have a negative effect on the fetus.
During breastfeeding, it is not recommended to use Terzhinan, however, if there are indications and a clear excess of benefits over risks, the drug is allowed to be used.
Side effects
Terzhinan as side effects can provoke the following symptoms:- Feeling of itching, burning and irritation in the vagina;
- Allergic reactions (rash, urticaria, skin itching, etc.).
Contraindications for use
Terzhinan tablets are contraindicated for use only if the woman has an individual hypersensitivity to the components of the drug.Tablets (candles) Terzhinan: release form, composition, indications, instructions for use, dosages, contraindications, side effects - video
Analogues
There are no synonyms for Terzhinan tablets, since there are no drugs on the domestic pharmaceutical market that have an identical composition of active ingredients. However, there is a fairly wide range of analogues that contain other active ingredients, but have exactly the same therapeutic effect.Terzhinan's analogues are the following drugs:
- Vagisept vaginal suppositories;
- Vagiferon vaginal suppositories;
- Gynomax vaginal suppositories;
- Ginalgin vaginal tablets;
- Giterna vaginal tablets;
- Klion-D 100 vaginal tablets;
- Clomegel gel vaginal;
- Metrogyl Plus vaginal gel;
- Metromicon-Neo vaginal suppositories;
- Neo-Penotran, Neo-Penotran forte and Neo-Penotran forte L vaginal suppositories;
- Polygynax vaginal capsules;
- Polygynax Virgo emulsion for insertion into the vagina;
- Elzhina vaginal tablets.
Cheaper analogues of Terzhinan
The cheapest analogues of Terzhinan are the following drugs:- Vagisept - 209 - 230 rubles;
- Ginalgin - 230 - 300 rubles;
- Clomegel - 60 - 120 rubles;
- Metromicon-Neo - 300 - 400 rubles for 14 tablets.
What is better than Terzhinan?
It is almost impossible to answer the question of what is better than Terzhinan, since in medical practice there is no concept of the best, but there is a definition of optimal. So, the drug that is most effective for this particular woman at the present time is considered optimal. This means that completely different drugs can be effective for the same disease in different periods of time, each of which will be optimal, but at different times.Terzhinan is an effective drug, well suited to many women, so it is considered a "good" remedy. If any woman at this particular moment did not fit the drug, then you will have to try using analogues. And the analogue that turns out to be the most suitable and effective, and will be the best for this particular woman at the current time.
According to the reviews of doctors and women, Vagisept, Poligynax, Gaynomax and Elzhina are good analogues of Terzhinan. Therefore, if Terzhinan for some reason did not suit the woman or was not effective enough, then it is recommended to try these drugs, which are highly likely to be better.