Onset of action of formoterol. Formoterol (Formoterol) price comparison for synonyms, availability in pharmacies
Name:
Formoterol (Formoterol)
Pharmachologic effect:
Beta-adrenergic agent, stimulating mainly beta-adrenergic receptors. It has a bronchodilator (expanding the lumen of the bronchi) effect. Inhibits (suppresses) the release of histamine and leukotrienes (biologically active substances produced in the body) from the lung tissue. The onset of action of the drug after 5 minutes, maximum after 2 hours, the duration of action with reversible bronchial obstruction (impaired airflow through the bronchi) is up to 10 hours.
Indications for use:
Prevention and treatment of bronchospasm (sharp narrowing of the lumen of the bronchi) in patients with obstructive bronchitis (inflammation of the bronchi, combined with impaired airflow through them), bronchial asthma, bronchospasm caused by an allergen or exercise.
Application method:
The drug is administered by inhalation. For relief (removal) of acute bronchospasm, a single breath (12 μg) of the drug should be taken, if necessary, take a second breath in a minute. The maximum daily dose is 96 mcg (8 puffs). For the prevention of asthma attacks, 12 mcg (1 breath) is administered 2 times a day after 12 hours, in severe cases, 24 mcg 2 times a day at least 8 hours later.
Undesirable phenomena:
Headache, dizziness, dry mouth, nervousness, small-amplitude muscle tremors, tachycardia (rapid heartbeat), nausea.
Contraindications:
Pregnancy, lactation, hypersensitivity to the drug or beta-agonists.
When using the drug, patients are not recommended to engage in activities that require increased attention or coordination of movements. Do not combine formoterol with other adrenomimetic agents, MAO inhibitors, tricyclic antidepressants. With caution, the drug is prescribed to patients suffering from diabetes mellitus, with myoma (benign tumor of the muscular layer) of the uterus.
Release form of the drug:
Metered aerosol for inhalation in an inhaler of 100 doses. One dose contains 12 micrograms of formoterol fumarate.
Storage conditions:
Drug from list B. In a cool place, avoiding freezing. Protect from direct sunlight and heat sources.
Synonyms:
Foradil.
Similar drugs:
Bronchoryl Theo-Asthalinforte Theo-Asthalin Shadrin Isadrinum Gambaran
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Many thanks!This page contains a list of all Formoterol analogues by composition and indications for use. A list of cheap analogues, and you can also compare prices in pharmacies.
- The cheapest analogue of Formoterol:
- The most popular analogue of Formoterol:
- ATH classification: Formoterol
- Active ingredients / composition: formoterol
Cheap analogues of Formoterol
| # | Name | Price in Russia | Price in Ukraine |
|---|---|---|---|
| 1 | salbutamol | 75 rub | 31 UAH |
| 2 | salbutamol Analogue by indication and method of application | 107 rub | -- |
| 3 | Analogue by indication and method of application | 118 rub | 8 UAH |
| 4 | salbutamol hemisuccinate Analogue by indication and method of application | 119 rub | -- |
| 5 | salbutamol Analogue by indication and method of application | 122 rub | -- |
When calculating the cost cheap analogues of Formoterol the minimum price was taken into account, which was found in the price lists provided by pharmacies
Popular analogues of Formoterol
| # | Name | Price in Russia | Price in Ukraine |
|---|---|---|---|
| 1 | formoterol Analogue in composition and indication | 305 rub | -- |
| 2 | indacaterol Analogue by indication and method of application | -- | 257 UAH |
| 3 | Analogue by indication and method of application | 150 rub | 107 UAH |
| 4 | salbutamol Analogue by indication and method of application | 75 rub | 31 UAH |
| 5 | salbutamol Analogue by indication and method of application | 107 rub | -- |
The list of drug analogues based on the statistics of the most requested drugs
All analogues of Formoterol
The above list of analogues of drugs, which indicates Substitutes Formoterol, is the most suitable, since they have the same composition of active ingredients and match the indications for use
Analogues by indication and method of application
| Name | Price in Russia | Price in Ukraine |
|---|---|---|
| salbutamol | -- | 148 UAH |
| salbutamol | -- | 34 UAH |
| salbutamol | 236 rub | 8 UAH |
| salbutamol | -- | -- |
| salbutamol | 75 rub | 31 UAH |
| 118 rub | 8 UAH | |
| salbutamol | -- | 4 UAH |
| salbutamol | -- | 221 UAH |
| salbutamol | -- | 41 UAH |
| salbutamol | 107 rub | -- |
| salbutamol | -- | -- |
| salbutamol | 122 rub | -- |
| salbutamol sulfate | -- | 46 UAH |
| salbutamol hemisuccinate | 119 rub | -- |
| fenoterol | -- | -- |
| 150 rub | 107 UAH | |
| fenoterol | 304 rub | 107 UAH |
| fenoterol | 125 rub | -- |
| fenoterol | 202 rub | -- |
| salmeterol | 8800 rub | 436 UAH |
| salmeterol | -- | 436 UAH |
| salmeterol | -- | -- |
| indacaterol | -- | 257 UAH |
Different composition, may coincide in indication and method of application
| Name | Price in Russia | Price in Ukraine |
|---|---|---|
| -- | -- | |
| ipratropium bromide, fenoterol | 202 rub | 133 UAH |
| ipratropium bromide, fenoterol | 334 rub | 145 UAH |
| 176 rub | -- | |
| salmeterol, fluticasone propionate | 446 rub | 170 UAH |
| salmeterol, fluticasone | -- | 170 UAH |
| salmeterol xinafoate, fluticasone propionate | 446 rub | 1500 UAH |
| salmeterol, fluticasone | -- | 170 UAH |
| salmeterol, fluticasone | 407 rub | -- |
| salmeterol, fluticasone propionate | -- | 83 UAH |
| salmeterol, fluticasone | -- | -- |
| salmeterol | 590 rub | -- |
| budesonide, formoterol | 799 rub | 263 UAH |
| budesonide, formoterol | 577 rub | -- |
| budesonide, formoterol | -- | -- |
| budesonide, formoterol fumarate dihydrate | 800 rub | -- |
| beclomethasone, formoterol | 1900 rub | 1900 UAH |
| mometasone, formoterol | 1257 rub | -- |
| vilanterol, fluticasone | 1563 rub | 1900 UAH |
| beclomethasone dipropionate, salbutamol | 730 rub | -- |
| fenoterol hydrobromide, ipratropium bromide | -- | -- |
| ipratropium bromide, fenoterol | 245 rub | 410 UAH |
| bromide, triphenate | 1909 rub | 502 UAH |
| glycopyrronium bromide, indacaterol | 2200 rub | -- |
| olodaterol, tiotropium bromide | 2395 rub | 710 UAH |
To compile a list of cheap analogues of expensive drugs, we use the prices provided by more than 10,000 pharmacies throughout Russia. The database of drugs and their analogues is updated daily, so the information provided on our website is always up-to-date as of the current day. If you have not found the analogue you are interested in, please use the search above and select the medicine you are interested in from the list. On the page of each of them you will find all possible options for analogues of the desired medicine, as well as prices and addresses of pharmacies in which it is available.
How to find a cheap analogue of an expensive medicine?
To find an inexpensive analogue of a drug, a generic or a synonym, we first of all recommend paying attention to the composition, namely to the same active ingredients and indications for use. The same active ingredients of the drug will indicate that the drug is a synonym for the drug, a pharmaceutical equivalent or a pharmaceutical alternative. However, do not forget about the inactive components of similar drugs, which can affect safety and efficacy. Do not forget about the advice of doctors, self-medication can harm your health, so always consult a doctor before using any medication.Formoterol price
On the sites below you can find prices for Formoterol and find out about availability at a pharmacy nearbyFormoterol instruction
INSTRUCTIONS
for medical use of the drug
Formoterol
(Formoterol)
Pharmachologic effect:
Beta-adrenergic agent, stimulating mainly beta-adrenergic receptors. It has a bronchodilator (expanding the lumen of the bronchi) effect. Inhibits (suppresses) the release of histamine and leukotrienes (biologically active substances produced in the body) from the lung tissue. The onset of action of the drug after 5 minutes, maximum after 2 hours, the duration of action with reversible bronchial obstruction (impaired airflow through the bronchi) is up to 10 hours.
Indications for use:
Prevention and treatment of bronchospasm (sharp narrowing of the lumen of the bronchi) in patients with obstructive bronchitis (inflammation of the bronchi, combined with impaired air passage through them); bronchial asthma; bronchospasm caused by an allergen or exercise.
Mode of application:
The drug is administered by inhalation. For relief (removal) of acute bronchospasm, a single breath (12 μg) of the drug should be taken, if necessary, take a second breath in a minute. The maximum daily dose is 96 mcg (8 puffs). For the prevention of asthma attacks, 12 mcg (1 breath) is administered 2 times a day after 12 hours, in severe cases, 24 mcg 2 times a day at least 8 hours later.
Side effects:
Headache, dizziness, dry mouth, nervousness, small-amplitude muscle tremors, tachycardia (rapid heartbeat), nausea.
Contraindications:
Pregnancy, lactation, hypersensitivity to the drug or beta-agonists.
When using the drug, patients are not recommended to engage in activities that require increased attention or coordination of movements. Do not combine formoterol with other adrenomimetic agents, MAO inhibitors, tricyclic antidepressants. With caution, the drug is prescribed to patients suffering from diabetes mellitus, with myoma (benign tumor of the muscular layer) of the uterus.
Release form:
Metered aerosol for inhalation in an inhaler of 100 doses. One dose contains 12 micrograms of formoterol fumarate.
Storage conditions:
List B. In a cool place, avoiding freezing. Protect from direct sunlight and heat sources.
Pharmacological group:
Medicines used to treat the bronchi and lungs
Anti-asthma medicines
Beta-adrenergic stimulants
pharmachologic effect
Beta-agonist. It acts mainly on β 2 -adrenergic receptors. It has a bronchodilator effect, stops and prevents bronchospasm. Inhibits the release of histamine, leukotrienes and prostaglandin D 2 from mast cells, basophils and sensitized cells of the bronchoalveolar tree.
Pharmacokinetics
When administered by inhalation, it is possible to swallow about 90% of the active substance. When taken orally, it is rapidly absorbed from the gastrointestinal tract. Absorption is 65%. Cmax is reached in 0.5-1 h. Plasma protein binding is 61-64%. T 1/2 - 2-3 hours Metabolized mainly by glucuronidation. It is excreted by the kidneys (70%) and through the intestines (30%). Renal clearance - 150 ml / min.
When inhaled, it is rapidly absorbed, C max is reached after 15 minutes, the concentration of the active substance in the lungs after inhalation with a turbuhaler is 21-37%. Bioavailability - 46%. Plasma protein binding - 50%. T 1/2 - 8 hours
Indications
Prevention and treatment of bronchospasm in patients with obstructive bronchitis, bronchial asthma.
Dosing regimen
Apply in the form of inhalation. The dose depends on the dosage form used and the age of the patient.
Side effect
Maybe: headache, nausea, dry mouth, tremor.
Seldom: muscle cramps, myalgia, tachycardia, dizziness, agitation, anxiety, sleep disturbances, nervousness, increased bronchospasm.
In some cases: hypersensitivity reactions (severe arterial hypotension, urticaria, angioedema, itching, exanthema), peripheral edema, changes in taste.
Contraindications for use
Hypersensitivity to formoterol or other beta-agonists, children under 5 years of age.
Use during pregnancy and lactation
During pregnancy and lactation, formoterol is used with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk of side effects for the fetus or child.
Use in children
Contraindicated in children under 5 years of age.
drug interaction
Formoterol should not be combined with adrenomimetic agents, MAO inhibitors, tricyclic antidepressants (the risk of side effects from the cardiovascular system increases).
With the simultaneous use of xanthine derivatives, corticosteroids, diuretics increase the likelihood of a hypokalemic effect of the drug.
With the simultaneous use of quinidine, disopyramide, procainamide, phenothiazines, antihistamines, tricyclic antidepressants increase the risk of developing ventricular arrhythmias.
Beta-blockers (including in the form of eye drops) partially or completely block the action of formoterol.
special instructions
Particular caution and close monitoring is required if it is necessary to use formoterol in patients with the following concomitant diseases: coronary artery disease; cardiac arrhythmia and conduction disorders, especially AV blockade of the III degree; severe heart failure; idiopathic subvalvular aortic stenosis; hypertrophic obstructive cardiomyopathy; thyrotoxicosis; known or suspected prolongation of the QT interval (QT corrected >0.44 sec).
Use with caution in patients with diabetes mellitus, uterine myoma.
Influence on the ability to drive vehicles and control mechanisms
Tremor or anxiety that occurs during treatment with beta-agonists can affect the patient's ability to drive a car, therefore, when using formoterol, it is not recommended to engage in potentially hazardous activities that require increased attention, rapid psychomotor reactions.
One dose of powder for inhalation Formoterol Easyhaler includes 12 mcg formoterol fumarate dihydrate .
Additional substances: lactose monohydrate .
Release form
Polymer inhaler. A lid with a lock is put on the dosing part. On the front of the device there is an inscription "Easyhaler". On the side of the device is a counter for the number of remaining doses. Inside the inhaler is a homogeneous white powder.
120 doses in a metered dose inhaler; one inhaler in a pack of cardboard.
pharmachologic effect
Bronchodilator action.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The drug from the group β-agonists . Formoterol acts mainly on β2-adrenergic receptors . It has a bronchodilatory effect, stops and prevents bronchospasm. Suppresses release leukotrienes, histamine and from basophils, mast cells, and sensitized bronchial cells.
Pharmacokinetics
It is permissible to swallow up to 90% of the active substance by inhalation. Rapidly absorbed from the intestine. Absorption reaches 65%. The time of onset of the maximum concentration is 30-60 minutes. Plasma protein binding is approximately 62-64%. The half-life is 2.5-3 hours. Transformed mainly through glucuronization . It is evacuated from the body by the kidneys and with feces.
When inhaled use is rapidly absorbed, the highest concentration occurs after 15 minutes. Bioavailability is 46%. Reacts with proteins by 50%. The half-life is approaching 8 hours.
Indications for use
Prevention and treatment of bronchospasm in individuals suffering from and obstructive.
Contraindications
- to the components of the drug.
- Children's age less than 6 years.
- Intolerance lactose, glucose-galactose malabsorption , flaw lactase .
Side effects
Nausea and dry mouth are the most common.
In more rare cases, muscle cramps are detected, tachycardia, myalgia , dizziness, anxiety, agitation, sleep disturbances, increased bronchospasm and nervousness. Even rarer - hypersensitivity reactions ( , heavy hypotension , itch, , exanthema ), changes in the sense of taste, peripheral edema.
Instructions for use Formoterol Easyhaler (Method and dosage)
Formoterol Easyhaler is used for inhalation only.
Bronchial asthma
For continuous maintenance therapy, 1 inhalation of the drug is prescribed twice a day; in some patients, 2 inhalations twice a day may be required. The highest daily dose with regular use is 4 inhalations.
If necessary, it is allowed to use additional inhalations, in addition to those prescribed, to relieve symptoms, but not more than 6 inhalations per day in total.
Do not carry out more than 3 inhalations at a time. Frequent (more than 2 times a day or more than 2 days a week) use of the drug or its use in dosages exceeding those recommended for maintenance treatment is a sign of insufficient control of bronchial asthma. In this case, it is necessary to revise the treatment regimen.
Prevention of exercise-induced bronchospasm
In such cases, 1 inhalation is carried out before the expected physical activity in about 15 minutes. In severe cases of the disease, the need for 2 inhalations is not excluded, but the maximum daily dose of 6 inhalations should not be exceeded.
Overdose
To date, there has not been enough clinical experience in the treatment of overdose, but it is assumed that an overdose of Formoterol Easyhaler is accompanied by nausea, headaches, vomiting, palpitations, ventricular arrhythmias, tachycardia , pressure change, metabolic acidosis, hyperglycemia, hypokalemia , prolongation of the QT interval.
Supportive and symptomatic treatment is indicated, concentration control potassium in blood. In severe cases, the patient must be hospitalized. It is allowed to use cautious (as a provocation of bronchospasm is possible) use cardioselective β-blockers .
Interaction
It is not recommended to combine formoterol from MAO inhibitors, adrenomimetic agents, tricyclic antidepressants , since the risk of adverse reactions from the circulatory system increases.
When used together glucocorticosteroids, xanthine derivatives, diuretics increase the likelihood of a hypokalemic effect from taking the drug.
Beta blockers (including eye drops) are capable of partially or completely stopping the action of formoterol .
When sharing Quinidine, Procainamide, Disopyramide, phenothiazines, tricyclic antidepressants, antihistamines increases the likelihood of ventricular arrhythmias .
Terms of sale
On prescription.
Storage conditions
Store below 30°C in a dry place. Keep away from children.
Best before date
Two years. After opening the package, the product is allowed to be used within 4 months.
special instructions
Careful monitoring and special caution is required if the drug is to be used in patients with ischemic heart disease , rhythm and conduction disorders of the heart, severe cardiac insufficiency, subvalvular idiopathic aortic stenosis, uterine myoma, obstructive hypertrophic cardiomyopathy, thyrotoxicosis, prolongation of the QT interval by ECG .
Formoterol Easyhaler may affect the ability to drive vehicles, so when using the drug is not recommended for such activities.
Analogues
Coincidence in the ATX code of the 4th level:The most famous analogues of Formoterol Easyhaler: Atimos, Zafiron, Oksis Turbuhaler,.
children
The drug is not used in children under 6 years of age
Children 6 years of age or older for ongoing maintenance treatment bronchial asthma 1 inhalation twice a day is prescribed. More than 2 inhalations per day are not recommended.
During pregnancy and lactation
It is possible to use the drug during these periods only according to strict indications and taking into account all the risks.
Composition and form of release of the drug
Capsules with powder for inhalation solid transparent, size No. 3, light brown; the contents of the capsules are white or almost white powder.
Excipients: sodium benzoate - 0.02 mg, lactose monohydrate - up to 12 mg.
The composition of the capsule shell: dye caramel (E150c) - 1.4388%, hypromellose - up to 100%.
10 pieces. - blister packs (3) in set. with a device for inhalation. or without it - packs of cardboard.
10 pieces. - blister packs (6) in set. with a device for inhalation. or without it - packs of cardboard.
pharmachologic effect
Beta-agonist. It acts mainly on β 2 -adrenergic receptors. It has a bronchodilator effect, stops and prevents bronchospasm. Inhibits the release of histamine, leukotrienes and prostaglandin D 2 from mast cells, basophils and sensitized cells of the bronchoalveolar tree.
Pharmacokinetics
When administered by inhalation, it is possible to swallow about 90% of the active substance. When taken orally, it is rapidly absorbed from the gastrointestinal tract. Absorption is 65%. Cmax is reached in 0.5-1 h. Plasma protein binding is 61-64%. T 1/2 - 2-3 hours Metabolized mainly by glucuronidation. It is excreted by the kidneys (70%) and through the intestines (30%). Renal clearance - 150 ml / min.
When inhaled, it is rapidly absorbed, C max is reached after 15 minutes, the concentration of the active substance in the lungs after inhalation with a turbuhaler is 21-37%. Bioavailability - 46%. Protein binding 50%. T 1/2 - 8 hours
Indications
Prevention and treatment of bronchospasm in patients with obstructive bronchitis, bronchial asthma.
Contraindications
Hypersensitivity to formoterol or other beta-agonists, children under 5 years of age.
Dosage
Apply in the form of inhalation. The dose depends on the dosage form used and the age of the patient.
Side effects
Maybe:, nausea, dry mouth, tremor.
Seldom: muscle cramps, myalgia, tachycardia, dizziness, agitation, anxiety, sleep disturbances, nervousness, increased bronchospasm.
In some cases: hypersensitivity reactions (severe arterial hypotension, urticaria, angioedema, itching, exanthema), peripheral edema, changes in taste.
drug interaction
Formoterol should not be combined with adrenomimetic agents, MAO inhibitors, tricyclic antidepressants (the risk of side effects from the cardiovascular system increases).
With the simultaneous use of xanthine derivatives, corticosteroids, diuretics increase the likelihood of a hypokalemic effect of the drug.
With the simultaneous use of quinidine, disopyramide, procainamide, phenothiazines, antihistamines, tricyclic antidepressants increase the risk of developing ventricular arrhythmias.
(including in the form of eye drops) partially or completely block the action of formoterol.
special instructions
Particular caution and close monitoring is required if it is necessary to use formoterol in patients with the following concomitant diseases: coronary artery disease; rhythm and conduction disturbances, especially AV blockade of the III degree; severe heart failure; idiopathic subvalvular aortic stenosis; hypertrophic obstructive cardiomyopathy; thyrotoxicosis; known or suspected prolongation of the QT interval (QT corrected >0.44 sec).
Use with caution in patients with diabetes mellitus, uterine myoma.
Influence on the ability to drive vehicles and control mechanisms
Tremor or anxiety that occurs during treatment with beta-agonists can affect the patient's ability to drive a car, therefore, when using formoterol, it is not recommended to engage in potentially hazardous activities that require increased attention, rapid psychomotor reactions.
Pregnancy and lactation
During and during lactation, formoterol is used with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk of side effects for the fetus or child.