Almagel suspension instructions for use of the tablet. Almagel, instructions for use for proper use
Composition and release form
5 ml of oral suspension contains aluminum hydroxide 300 mg (equivalent to 200 mg aluminum oxide), magnesium hydroxide 100 mg; in plastic bottles of 170 ml complete with a dosing spoon, 1 bottle in a cardboard box.
Characteristic
A suspension of white or slightly grayish color with a characteristic sweetish taste and smell of lemon.
Pharmacological action
Pharmacological action- adsorbent, enveloping, antacid.Neutralizes hydrochloric acid and reduces the activity of pepsin, gastric juice, protects the gastrointestinal mucosa from damaging effects.
Pharmacodynamics
It is evenly distributed throughout the gastric mucosa and provides long-lasting gastroprotection. It has buffering and antacid properties: between doses, the pH of gastric juice is maintained from 4-4.5 to 3.5-3.8. Sorbitol has a choleretic and mild laxative effect. The therapeutic effect appears after 3-5 minutes and lasts 70 minutes.
Pharmacokinetics
Practically not absorbed from the gastrointestinal tract.
Indications of the drug Almagel ®
Gastric ulcer and duodenum(acute phase), acute or chronic gastritis against the background of normal or increased secretion (exacerbation phase), reflux esophagitis, diaphragmatic hernia, duodenitis, enteritis, gastrointestinal disorders caused by poor diet, intake medicines(NSAIDs, glucocorticoids), drinking coffee or alcohol, smoking.
Contraindications
Hypersensitivity, pronounced violations kidney function, Alzheimer's disease, neonatal period, breastfeeding.
Use during pregnancy and breastfeeding
During pregnancy, use is possible for no longer than 3 days. Breastfeeding should be stopped during treatment.
Side effects
From the gastrointestinal tract: taste disturbance, nausea, vomiting, spasm, pain in the epigastric region, constipation.
From the side of metabolism: hypercalciuria, hypermagnesemia, hypophosphatemia.
Others: drowsiness, osteomalacia, dementia and swelling of the extremities (due to chronic renal failure).
Interaction
Reduces the effectiveness of tetracyclines, H 2 -antihistamines, cardiac glycosides, iron salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indomethacin, ketoconazole, etc. (when administered together, an interval between doses of at least 1-2 hours is recommended).
Directions for use and doses
Orally, 0.5 hours before meals (for peptic ulcers of the stomach and duodenum between main meals) and at night, adults 1-3 dosage spoons 3-4 times a day. Maintenance dose - 1 dosage spoon 3-4 times a day for 2-3 months. Preventive therapy- 1-2 dosage spoons.
For children, strictly as prescribed by the doctor: up to 10 years - 1/3 dose for adults, 10-15 years - 1/2 dose.
The maximum daily dose is 16 dosage spoons, with this dose the duration of treatment is no more than 2 weeks.
The suspension should be shaken before use.
In case of a disease accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of the listed symptoms, they switch to taking Almagel.
Overdose
Symptoms: inhibition of gastrointestinal motility.
Treatment: prescription of laxatives.
Precautions
At long-term use it is necessary to ensure sufficient intake of phosphorus from food.
Special instructions
At functional disorders accompanied by nausea, vomiting, and abdominal pain, treatment begins with Almagel A.
Storage conditions for the drug Almagel ®
At a temperature not exceeding 25 °C. Do not freeze!Keep out of the reach of children.
Shelf life of the drug Almagel ®
2 years.Do not use after the expiration date stated on the package.
Synonyms of nosological groups
| ICD-10 rubric | Synonyms of diseases according to ICD-10 |
|---|---|
| K21.0 Gastroesophageal reflux with esophagitis | Reflux gastritis |
| Reflux esophagitis | |
| Erosive-ulcerative esophagitis | |
| K25 Stomach ulcer | Helicobacter pylori |
| Pain syndrome with gastric ulcer | |
| Inflammation of the gastric mucosa | |
| Inflammation of the gastrointestinal mucosa | |
| Benign gastric ulcer | |
| Exacerbation of peptic ulcer | |
| Exacerbation of gastric ulcer | |
| Organic gastrointestinal disease | |
| Postoperative gastric ulcer | |
| Ulcer recurrence | |
| Symptomatic stomach ulcers | |
| Helicobacteriosis | |
| Chronic inflammatory disease upper sections Gastrointestinal tract associated with Helicobacter pylori | |
| Erosive and ulcerative lesions of the stomach | |
| Erosive lesions of the stomach | |
| Erosion of the gastric mucosa | |
| Peptic ulcer | |
| Gastric ulcer | |
| Gastric ulcer | |
| Ulcerative lesions of the stomach | |
| K26 Duodenal ulcer | Pain syndrome in duodenal ulcer |
| Pain syndrome in gastric and duodenal ulcers | |
| Disease of the stomach and duodenum associated with Helicobacter pylori | |
| Exacerbation of peptic ulcer | |
| Exacerbation of duodenal ulcer | |
| Peptic ulcer of the stomach and duodenum | |
| Recurrence of duodenal ulcer | |
| Symptomatic ulcers of the stomach and duodenum | |
| Helicobacteriosis | |
| Helicobacter pylori eradication | |
| Erosive and ulcerative lesions of the duodenum | |
| Erosive and ulcerative lesions of the duodenum associated with Helicobacter pylori | |
| Erosive lesions of the duodenum | |
| Duodenal ulcer | |
| Ulcerative lesions of the duodenum | |
| K29 Gastritis and duodenitis | Duodenitis |
| Exacerbation of gastroduodenitis against the background of peptic ulcer | |
| K29.1 Other acute gastritis | Acute gastritis (erosive) |
| Erosive gastritis | |
| Acute gastritis | |
| K29.5 Chronic gastritis, unspecified | Pain in chronic gastritis with high acidity |
| Chronic gastritis | |
| Gastroenteritis | |
| Gastroenteritis | |
| Metaplasia of the gastric mucosa | |
| Acute gastroenteritis | |
| Chronic gastritis | |
| Chronic diseases of the digestive system | |
| Chronic autoimmune gastritis | |
| Chronic gastritis | |
| Chronic gastritis in the acute stage | |
| Chronic gastritis with normal secretory function | |
| Chronic gastritis with normal gastric secretory function | |
| Chronic gastritis with normal secretion | |
| Chronic gastritis with increased and normal secretory function of the stomach | |
| Chronic gastritis with increased secretory function | |
| Chronic gastritis with increased secretory function of the stomach | |
| Chronic gastritis with increased secretion | |
| Chronic gastritis with decreased secretory function | |
| Chronic gastritis with secretory insufficiency | |
| K52.9 Non-infectious gastroenteritis and colitis, unspecified | Hemocolitis |
| Digestive tract infections | |
| Infectious disease of the gastrointestinal tract | |
| Antibiotic-associated colitis | |
| Collagenous colitis | |
| Chronic diarrhea | |
| Old Gut Syndrome | |
| Mucous colitis | |
| Chronic colitis | |
| Chronic enteritis | |
| Z72.4 Inappropriate diet and bad habits in nutrition | Dyspepsia caused by unusual foods or overeating |
| Long-term diet therapy | |
| Long-term or low-calorie diets | |
| Gastrointestinal disorders caused by poor diet | |
| Inadequate nutrition | |
| Irregular eating | |
| Unbalanced diets | |
| Overeating | |
| Food poisoning | |
| Errors in diet | |
| Dieting | |
| Following a strict diet | |
| Special diets |
Antacid drug
Active ingredients
Magnesium hydroxide paste
- algeldrate (aluminum hydroxide gel) (algeldrate)
Release form, composition and packaging
◊ Oral suspension white or almost white, with a characteristic lemon smell; During storage, a layer of transparent liquid may form on the surface; vigorously shaking the bottle will restore the homogeneity of the suspension.
Excipients: sorbitol - 801.15 mg, hyaetellose - 10.9 mg, methyl parahydroxybenzoate - 10.9 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 818 mcg, lemon oil - 1.635 mg, ethanol 96% - 98.1 mg, purified water - up to 5 ml.
170 ml - bottles (1) complete with a dosing spoon (5 ml) - cardboard packs.
Pharmacological action
An antacid drug that is a balanced combination of algeldrate (aluminum hydroxide) and magnesium hydroxide. Neutralizes free hydrochloric acid in the stomach, reduces the activity of pepsin, which leads to a decrease in the digestive activity of gastric juice.
Has an enveloping, adsorbing effect. Protects the gastric mucosa by stimulating the synthesis of prostaglandins (cytoprotective effect). Protects the mucous membrane from inflammatory and erosive-hemorrhagic lesions as a result of the use of irritating and ulcerogenic agents such as ethanol, NSAIDs (for example, indomethacin, diclofenac), corticosteroids.
The therapeutic effect after taking the drug occurs within 3-5 minutes. The duration of action depends on the rate of gastric emptying. When taken on an empty stomach, the effect lasts up to 60 minutes. When taken an hour after a meal, the antacid effect can last up to 3 hours. It does not cause secondary hypersecretion of gastric juice.
Pharmacokinetics
Algeldrat
A small amount of the drug is absorbed, which practically does not change the concentration of aluminum salts in the blood. Excreted through the intestines.
Magnesium hydroxide
Magnesium ions are absorbed in small quantities (about 10% of the dose taken) and do not change the concentration of magnesium in the blood. Usually distributed locally. Magnesium hydroxide is excreted through the intestines.
Indications
Treatment
- chronic gastritis with increased and normal secretory function of the stomach (in the acute phase);
- acute duodenitis, enteritis, colitis;
— peptic ulcer stomach and duodenum (in the acute phase);
- hernia hiatus diaphragms;
- gastroesophageal reflux, reflux esophagitis, duodenogastric reflux;
- symptomatic gastrointestinal ulcers of various origins;
— erosion of the mucous membrane of the upper gastrointestinal tract;
— acute pancreatitis, exacerbation chronic pancreatitis;
- heartburn and epigastric pain after errors in diet, excessive consumption of ethanol, nicotine, coffee, medicines irritating the gastric mucosa.
Prevention
- reduction of irritant and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.
Contraindications
- severe (due to the risk of developing hypermagnesemia and aluminum intoxication);
- Alzheimer's disease;
- hypophosphatemia;
- pregnancy;
— childhood up to 10 years;
— congenital fructose intolerance (the drug contains sorbitol);
— increased sensitivity To active substances And auxiliary components drug.
Dosage
The drug is taken orally. Before each dose, the suspension must be thoroughly homogenized by shaking the bottle.
Treatment
The drug is taken 45-60 minutes after meals and in the evening before bedtime.
Adults and children over 15 years old prescribed 5-10 ml (1-2 measuring spoons) 3-4 times/day. If necessary, the single dose can be increased to 15 ml (3 scoops). Children aged 10 to 15 years prescribed at a dose equal to half the dose for adults.
After reaching therapeutic effect daily dose reduce to 5 ml (1 measuring spoon) 3-4 times a day for 15-20 days.
Prevention
5-15 ml 15 minutes before taking medications with irritating effects.
Side effects
From the outside digestive system: possible - constipation, which goes away after reducing the dose; in rare cases - nausea, vomiting, stomach spasms, changes in taste.
From the outside nervous system: with prolonged use of the drug in patients with renal failure and patients on dialysis, changes in mood and mental activity are possible.
Others: in rare cases - allergic reactions and hypermagnesemia; at long-term use in high doses (in combination with phosphorus deficiency in food), osteomalacia may develop.
Overdose
Symptoms: if the dose is exceeded once - constipation, flatulence, metallic taste in the mouth. With prolonged use in high doses, formation, development of severe constipation, slight drowsiness, and hypermagnesemia are possible. There may also be signs metabolic alkalosis: changes in mood or mental activity, numbness or muscle pain, irritability and fatigue, slow breathing, unpleasant taste.
Treatment: it is necessary to immediately take measures to quickly remove the drug from the body - gastric lavage, stimulation of vomiting, taking activated charcoal.
Drug interactions
May adsorb some drugs, thereby reducing their absorption. Therefore, when using other drugs simultaneously, it is necessary to maintain an interval of 1-2 hours between taking Almagel and other drugs.
Almagel changes the pH of gastric juice towards the alkaline side, which can affect the effect of a significant number of drugs when used simultaneously.
Almagel reduces the effect of histamine H2 receptor blockers (ranitidine, famotidine), cardiac glycosides, iron salts, lithium preparations, quinidine, mexiletine, phenothiazine drugs, tetracycline antibiotics, ciprofloxacin, isoniazid and ketoconazole.
When prescribing enteric forms of drugs simultaneously, it should be remembered that an increase in the pH of gastric juice caused by taking the drug Almagel can lead to accelerated destruction of the enteric membrane and thereby cause irritation of the mucous membrane of the stomach and duodenum.
Almagel may affect the results of some laboratory and functional studies and tests: it reduces the level of gastric secretion when determining the acidity of gastric juice; alters test results using technetium (99m Tc), such as bone scintigraphy and some esophageal tests; increases the concentration of phosphorus in the blood serum, changes the pH values of the blood serum and urine.
Special instructions
The use of the drug is not recommended in patients with severe constipation, stomach pain of unknown origin and suspected ulcerative colitis, diverticulosis, colostomy or ileostomy, chronic diarrhea, acute hemorrhoids, changes in acid-base balance in the body, as well as the presence of metabolic alkalosis, severe heart failure, toxicosis of pregnancy, impaired renal function ((KK<30 мл/мин) из-за опасности развития гипермагниемии и алюминиевой интоксикации).
The drug does not contain sugar, which allows it to be taken by patients with diabetes.
The drug contains sorbitol and is therefore contraindicated in cases of congenital fructose intolerance.
Impact on the ability to drive vehicles and operate machinery
Almagel does not affect the ability to drive a car or operate machinery. When taken in the recommended daily dose, the ethanol contained in the drug does not affect the ability to drive a car or operate machinery.
Pregnancy and lactation
Experimental studies animal studies have shown no teratogenic potential or other adverse effects on the embryo and/or fetus.
There are no clinical data on the use of Almagel in pregnant women. The drug is not recommended for use during pregnancy, but if the expected benefit to the mother outweighs the potential risk to the fetus, Almagel should be taken under medical supervision for no more than 5-6 days.
There is no data on the release of the active substances of the drug into breast milk. Almagel can be used during breastfeeding only after a thorough assessment of the ratio of the expected benefit to the mother and the potential risk to the child. During lactation, the drug is recommended to be used for no more than 5-6 days under medical supervision.
Use in childhood
The drug is contraindicated for use in children under 10 years of age.
For impaired renal function
The use of the drug is contraindicated in severe renal failure (due to the risk of developing hypermagnesemia and aluminum intoxication).
In patients with renal failure with prolonged use of the drug (more than 20 days), regular monitoring of the concentration of magnesium in the blood serum is necessary.
For liver dysfunction
Conditions for dispensing from pharmacies
The drug is approved for use as an over-the-counter product.
Storage conditions and periods
The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C; do not freeze. Shelf life - 2 years.
Almagel is a non-absorbable antacid, which is a balanced combination of aluminum hydroxide and magnesium. Provides rapid and long-lasting neutralization of hydrochloric acid and reduces the activity of pepsin in the stomach, while the pH level of gastric juice does not exceed 5-6. The components of the drug are well dispersed, which increases their active surface and provides closer contact with the surface of the mucous membrane of the stomach and duodenum. At the same time, the evacuation of gastric contents slows down and the neutralizing effect is prolonged. Cytoprotective activity does not depend on acid-neutralizing ability, but is associated with activation of the synthesis of prostaglandins E. Based on the ability of the drug to bind bile acids and lysolecithin, as well as to have a gastroprotective effect, it can be used in the complex treatment of duodenogastroesophageal reflux. The effect of the drug begins 3-5 minutes after administration and lasts about 3 hours.
Aluminum hydroxide neutralizes hydrochloric acid in the stomach, forming aluminum chloride. Under the influence of the alkaline environment of the intestine, the latter turns into alkaline aluminum salts, which are poorly absorbed and excreted in feces. With normal renal function, serum aluminum levels remain virtually unchanged. About 10% of magnesium hydroxide is absorbed in the intestine. Magnesium hydroxide neutralizes hydrochloric acid in the stomach and turns into magnesium carbonate, and the concentration of magnesium ions in the blood remains virtually unchanged. In patients with chronic renal failure, the level of aluminum and magnesium ions may increase to toxic levels due to impaired excretion.
Almagel A additionally contains benzocaine, a local anesthetic. It exhibits a local anesthetic effect in the presence of severe pain. Benzocaine is absorbed in minimal quantities and has virtually no effect on the body. Its local anesthetic effect occurs 1-2 minutes after application of the suspension.
Almagel Neo contains simethicone, which helps reduce flatulence. Simethicone is a stable silicone compound that is not absorbed in the digestive tract and promotes the natural elimination of gases and their absorption by the intestinal walls. Simethicone acts in the lumen of the small intestine and is excreted unchanged from the body.
Indications for use of the drug Almagel
Used both as monotherapy and in complex therapy of inflammatory and erosive changes in the mucous membranes of the esophagus, stomach or duodenum in the following diseases: gastritis, esophagitis, duodenitis, gastroesophageal reflux disease, hiatal hernia, peptic ulcer of the stomach and duodenum in the presence of gastroesophageal reflux (heartburn).
In cases where the listed conditions are accompanied by manifestations of flatulence, the use of Almagel Neo is recommended. Almagel A is indicated for severe pain, after relief of which they proceed to the use of Amagel or Almagel T.
Use of the drug Almagel
Take orally 10 minutes before meals or 1.5-2 hours after meals, or as needed.
Almagel is recommended for adults and children over 15 years of age: 5-10 ml (1-2 scoops) 3 times a day. If necessary, the dose can be increased to 15 ml (3 scoops).
Children aged 10-15 years are prescribed half the recommended dose for adults.
The duration of treatment is determined by the doctor.
Almagel T is used in adults and children over 12 years of age as needed at a dose of 500-1000 mg (1-2 tablets), but not more than 6 times a day.
Almagel A is used in adults with severe pain, 5-10 ml (1-2 scoops) 3-4 times a day 10-15 minutes before meals or when pain occurs. The duration of treatment with Almagel A should not exceed 7 days, then proceed to the use of Almagel, Almagel T or Almagel Neo for 15-20 days.
Almagel Neo is used in adults and children over 14 years of age in the presence of flatulence, 10-15 ml of suspension (2-3 scoops) 4 times a day, an hour after meals and in the evening before bed. After achieving the desired effect, the dose is reduced to 10 ml 4 times a day.
The maximum daily dose (60 ml) can be used for no more than 4 weeks.
Contraindications to the use of the drug Almagel
Hypersensitivity to substances included in the drug; severe renal dysfunction; intestinal obstruction; suspicion of appendicitis; bleeding from the digestive canal of unknown origin; ulcerative colitis; conditions causing disturbances in water and electrolyte balance. Age restrictions— Almagel is contraindicated for children under 10 years of age; Almagel Neo - for children under 14 years old, Almagel T - for children under 12 years old, Almagel A is contraindicated for children.
Side effects of the drug Almagel
Changes in taste sensations (the appearance of a chalky taste), nausea, vomiting, diarrhea or constipation, and changes in the color of stool may be noted. When using Almagel A, local and systemic allergic reactions can be detected.
Special instructions for the use of the drug Almagel
With long-term (more than 20 days) use, it is necessary to regularly monitor the patient's condition. The drug does not contain sugar and can be used in patients with diabetes. The drug contains sorbitol, which is contraindicated in cases of congenital fructose intolerance. Almagel and Almagel A contain parabens, which can cause allergic reactions.
Use during pregnancy and lactation. During pregnancy and breastfeeding, the doctor may prescribe Almagel, Almagel T or Almagel Neo, weighing the risk/benefit ratio. In this case, it is recommended to use the drug for no more than 5-6 days and only under the supervision of a doctor. It is not recommended to prescribe for toxicosis of pregnant women (nephropathy, etc.). Almagel A is contraindicated during pregnancy and breastfeeding due to the benzocaine content.
Interactions of the drug Almagel
Almagels reduce the absorption of reserpine, histamine blockers, digitalis glycosides, iron salts, lithium preparations, quinidine, mexiletine, phenothiazine drugs, tetracycline antibiotics, ciprofloxacin, isoniazid and ketoconazole. The interval between doses of Almagel and other medications should be at least 1-2 hours.
Almagel drug overdose, symptoms and treatment
Long-term use in high doses can cause constipation or diarrhea, phosphorus deficiency syndrome (loss of appetite, muscle weakness, weight loss). Neurotoxicity, osteomalacia, osteoporosis, hypermagnesemia, and electrolyte disturbances may occur in patients with renal failure.
Storage conditions for the drug Almagel
In a place protected from light at a temperature not exceeding 25 ° C.
List of pharmacies where you can buy Almagel:
- Saint Petersburg
The name Almagel refers to a number of antacid drugs that have been produced on the pharmacological market for more than 40 years. The products have adsorbent, antacid, and gastroprotective properties. According to the instructions for use of Almagel, the drug is prescribed for the treatment of peptic ulcer of the duodenum and stomach, acute and chronic gastritis, fissure hernia and some other diseases.
The basis of the drug consists of substances such as aluminum oxide and magnesium. A certain combination of these components helps in the treatment of various diseases associated with increased acidity of the gastrointestinal tract.
Almagel is available in the form of gel, suspension and tablets. Today three types of the drug are available:
- Almagel;
- Almagel A;
- Almagel Neo.
The first type of drug consists of the basic components mentioned above (in addition to auxiliary components in minor concentrations). Aluminum hydroxide reduces stomach acidity, and magnesium hydroxide has a laxative effect, neutralizing the work of the first component, which can cause a slowdown in gastrointestinal motility and constipation.
Almagel A contains an additional element - benzocaine, which has an analgesic effect on the mucous membranes. It is thanks to this element that the drug is indicated for patients to relieve pain caused by inflammatory processes in the mucous membranes of the stomach, esophagus or duodenum.
Almagel Neo additionally includes simethicone, a substance that prevents increased gas formation. Diseases of the stomach and duodenum are often accompanied by disturbances in the entire digestive process, which leads to an increase in the activity of microflora and increased formation of gases in the intestines. During pregnancy, Almagel Neo is not used, but instead, under special circumstances, the classic version of the drug is prescribed.
Pharmacological action
Almagel is an antacid drug. Its action is based on local long-term neutralization of constantly formed gastric juice. According to the instructions, Almagel reduces the content of hydrochloric acid in gastric juice to the optimal level. The product has a local anesthetic effect
The drug produces a slight laxative effect and is a choleretic agent. Aluminum hydroxide, which is part of Almagel as one of the active components, inhibits the secretion of pepsin. Coming into contact with hydrochloric acid, it neutralizes it by forming aluminum chloride.
Magnesium hydroxide, in turn, neutralizes hydrochloric acid due to the formation of magnesium chloride, which neutralizes the property of aluminum chloride to provoke constipation.
Sorbitol improves bile secretion, has a mild laxative effect, and has a carminative effect.
The drug acts for a long time, uniformly normalizing the acidity of hydrochloric acid. Almagel acts on the human body without the formation of carbon dioxide bubbles, which are the cause of flatulence and a secondary increase in the secretion of hydrochloric acid.
The drug does not cause a sharp shift in the pH of the stomach towards the alkaline side. The acidity level is maintained within 4.0-3.5.
Also, the use of Almagel does not disturb the water-electrolyte balance, does not provoke the formation of stones in the urinary tract and does not develop alkalosis.
The structure of Almagel allows it to gently and effectively envelop the gastric mucosa, which contributes to the uniform action of the drug on its entire surface. After taking one dose of the drug, the therapeutic effect begins after 3-5 minutes and lasts 70 minutes.
Indications for use of Almagel
According to the instructions for use of Almagel, the drug is indicated for diseases such as:
- Peptic ulcer of the stomach and duodenum (with exacerbations);
- Acute gastritis with increased acidity;
- Foodborne infectious diseases of the gastrointestinal tract;
- Esophagitis;
- Hiatal hernia in the diaphragm;
- Duodenitis, enteritis;
- Flatulence;
- Pain and discomfort in the abdomen due to eating disorders, dieting, abuse of coffee, nicotine and alcohol, after taking certain medications.
For prophylactic purposes, Almagel is prescribed to prevent the occurrence of ulcerative lesions of the gastrointestinal tract in parallel with the use of glucocorticosteroids and non-steroidal anti-inflammatory drugs.
Instructions for use of Almagel
Almagel is used orally in dosages of 5-10 ml of suspension/gel or 2-3 tablets 1-2 hours after meals and at night. If the drug is prescribed for the treatment of stomach ulcers, then it should be taken half an hour before meals. If necessary, the single dose is increased to 15 ml (up to 3-4 tablets). When the therapeutic effect is achieved, as part of maintenance therapy Almagel is taken 5 ml three times a day (or 1 tablet) for 2-3 months. Children aged 4 to 12 months are prescribed 7.5 ml, over one year - 15 ml three times a day.
The instructions for use of Almagel indicate that for the purpose of prevention, the product should be taken in 5-10 ml or 1-2 tablets before a possible irritant effect on the gastrointestinal mucosa occurs.
To make the drug more effective, the tablets must be chewed thoroughly or held in the mouth under the tongue for a while until Almagel is completely dissolved. The gel or suspension must be homogenized before use by shaking the bottle or thoroughly kneading the package between your fingers.
Side effects of Almagel
The use of Almagel may cause some side effects, such as nausea, vomiting, taste disturbances, constipation, cramping abdominal pain, and sometimes drowsiness.
Long-term use of the drug in some cases leads to osteomalacia in patients who are predisposed to disorders of phosphorus-calcium metabolism and who eat food with a lack of phosphorus.
If you take Almagel for a long time and in high doses, then typical side effects are:
- hypocalcemia;
- hypermagnesemia;
- hypophosphatemia;
- hypercalciuria;
- nephrocalcinosis;
- hyperaluminemia;
- osteoporosis;
- encephalopathy;
- renal dysfunction;
- osteomalacia.
When taking Almagel, people suffering from kidney failure may develop the following symptoms: decreased blood pressure, thirst.
Contraindications
Contraindications to taking Almagel are:
- Alzheimer's disease;
- severe renal dysfunction;
- child's age up to 1 month;
- individual intolerance to the components of the drug or hypersensitivity to them.
Almagel during pregnancy
In some cases, during pregnancy, Almagel can be taken, but not more than 3 days. However, during lactation it is better to avoid taking the drug.
Treatment with Almagel during pregnancy should be carried out strictly under the supervision of a doctor, and there are a number of restrictions on taking Almagel A and Almagel Neo. It is also prohibited to take this drug for toxicosis.
Almagel is one of the antacid medications that is prescribed for gastrointestinal diseases with acidity disorders. It is able to neutralize hydrochloric acid, which is found in the gastric juice of every person. Before starting treatment, it is recommended that you read the section “Instructions for use of Almagel”.
The drug contains an active ingredient called aluminum hydroxide. This substance is an integral part of all antacid drugs, since it is it that actively neutralizes the acidity of hydrochloric acid. As a result of interaction with aluminum hydroxide, a substance is formed - aluminum chloride.
The next component is magnesium hydroxide. It is also able to neutralize the acidic environment of gastric juice, while preventing the occurrence of such side effects as constipation. This undesirable effect can be caused by the formation of aluminum chloride.
D-sorbitol is also added to the medicine, which can increase the amount of bile produced and also has a secondary laxative effect.
Almagel A, in addition to the above components, contains benzocaine, which is responsible for the local anesthetic effect.
Among the properties of the medicinal substance Almagel, the following should be highlighted:
- acid neutralizing;
- adsorbent;
- gastroprotective;
- and enveloping.
The action of the drug is aimed at neutralizing the hydrochloric acid of gastric juice. In addition, Almagel is capable of providing a local anesthetic effect, which helps overcome the main symptom of gastrointestinal diseases - pain. The medicinal substance is also capable of taking part in the production of bile (accelerates and improves the excretion of bile). Almagel can be classified as a laxative medication due to the content of the D-sorbitol component.
The action of Almagel is quite long-lasting, which allows you to control the acidity of hydrochloric acid. The uniqueness of the drug lies in the fact that the chemical reaction occurs without the formation of carbon dioxide. This approach avoids the side effect of flatulence.
In addition, the drug does not harm the acid-base balance. The pH shift is not abrupt, and the stomach contents do not become alkaline. Almagel is able to maintain an optimal pH level, which is normally 4.0.
The drug has a very gentle effect on the body and does not provoke water-electrolyte imbalance. After taking Almagel, there were no cases of stone formation in the renal and urinary systems, and the development of alkalosis was not registered.
The drug itself is available in the form of a gel. It is in this state that Almagel is able to evenly envelop the inner wall of the stomach.
The effect of the drug begins within a few minutes, and its duration lasts just over one hour. This effect is observed after the first dose of Almagel.
Indications for use
The drug is mainly prescribed for diseases of the gastrointestinal tract. Among them, the most common are:
The last point will be appropriate in terms of preventing the re-development of ulcers in the gastrointestinal tract during the use of non-steroidal anti-inflammatory drugs and hormones (glucocorticosteroids).
Contraindications
You should refrain from taking Almagel if you have the following pathological conditions:
Attention! The drug should be taken with caution by the following group of people:
- women during lactation;
- people suffering from long-term constipation;
- patients with ulcerative colitis;
- patients with chronic diarrhea;
- patients with pain of unknown etiology.
To find out how to take Almagel, you should read the rules indicated on the antacid label. The drug is taken only orally. Immediately before each use, shake the bottle thoroughly.
Dosage of the drug
Prescribe the drug 1-2 scoops at a time. If there is no visible result, then, on the doctor’s recommendation, the dosage is increased to three measuring spoons at a time. The drug is taken four times a day, before the main meal (30-40 minutes before) and at night. The maximum daily dosage of the drug can be up to 16 teaspoons.
Duration of therapy: two weeks or more. If the drug was used at the maximum dose, the duration of treatment should not exceed 14 days.
- Children's dosage of Almagel:
Children under ten years of age are prescribed one third of the adult dosage, and patients aged ten to fifteen years can already take half of the adult dosage.
Attention!
If the disease of the gastrointestinal tract is accompanied by symptoms such as nausea, repeated vomiting and pain in the epigastric region, then treatment should begin with taking Almagel A. After these symptoms have been eliminated, you can switch to Almagel. This scheme is due to the content of bisocaine in Almagel A, which is able to relieve pain.
Side effects
The following conditions may develop due to the use of Almagel:
- nausea;
- prolonged constipation;
- general malaise and drowsiness;
- taste hallucinations;
- repeated vomiting;
- spasmodic pain in the epigastric region.
In case of long-term use of the drug, the following complication may develop: osteomalacia in patients who do not eat properly (lack of food rich in phosphorus in the diet) and in persons predisposed to impaired metabolism of calcium and phosphorus.
Taking Almagel during pregnancy
The appropriateness of using an antacid by a pregnant woman is determined by the attending physician. In case of prescribed treatment with Almagel, preference should be given to Almagel A. It can be taken during pregnancy, but not more than three days. The drug is contraindicated during breastfeeding.
Interaction with other medications
Almagel A is contraindicated in combination with sulfonamide drugs, since the benzocaine contained in its composition is an antibiotic antagonist.
Release form of the drug : bottles of 170 milliliters and 200 milliliters.
Storage conditions
The optimal storage temperature for the drug is from 0 to 25 degrees Celsius.
Best before date : 5 years.
Analogs
Among the antacid drugs, the following are also distinguished:
Today you can find Almagel in any pharmacy. The average price for the drug varies from 150 rubles and can reach up to 190 rubles per package.
The cost largely depends on the manufacturer and the locality (for example, in Moscow the drug can cost more than 200 rubles, but in pharmacies in Yekaterinburg the drug can be purchased for 170 rubles).
It has been proven that taking Almagel provokes increased excretion of calcium ions in the urine, and the ability to absorb phosphates from food is reduced. This leads to disruption of phosphate and calcium metabolism. Taking this into account, many doctors prescribe drugs containing phosphorus together with Almagel.
Patients with a history of chronic renal failure may have the following side effects while taking Almagel: edema and increased levels of magnesium ions in the blood. In severe cases, dementia may develop.
One of the varieties of Almagel is “Almagel Neo”, which is able to reduce the formation of intestinal gases due to the content of simethicone in its composition. "Almagel Neo" is indicated for patients with flatulence.
On sale in pharmacies you can find another analogue of Almagel - Phosphalugel. Let's look at what is better: Almagel or Phosphalugel?
Many people confuse these medications because they are very similar in composition. That is why it is very difficult to say which antacid drug is better. However, it should be noted that Phosphalugel has more properties. This allows it to be prescribed in various areas (not only as a symptomatic drug for diseases of the gastrointestinal tract). It can act as an absorbent and enveloping substance.
Unlike Almagel, Phosphalugl does not lead to disruption of the metabolism of phosphates and calcium. This property allows for longer administration of the drug. In addition, Phosphalugel can be prescribed to pregnant women, infants and elderly patients. However, it is definitely impossible to say that any drug is better. Treatment for each patient is selected individually by the doctor.
The drug is available without a prescription. You can buy the drug at any pharmacy. However, you should remember that taking medication on your own can harm your health. Before purchasing, you should consult your doctor.
It is imperative to observe the interval between taking Almagel Neo and other medications, which is about 1-2 hours. The drug is prescribed in teaspoons, which is equal to 5 milliliters of the active substance.
