Bactroban nasal ointment. Nasal ointment "Bactroban": reviews. Medicine "Bactroban": instructions, use, price.
Skin infections and inflammation are extremely common problems. And in such cases, Bactroban nasal ointment is often prescribed. Reviews from doctors and patients confirm that this remedy effectively copes with a host of ailments, including bacterial ones. So what does it contain? What properties does it have? Are there possible complications during therapy? How much does the ointment cost in pharmacies? The answers to these questions will be of interest to many.
Release form and description of composition
Today, many are interested in the question of what “Bactroban” (nasal ointment) is, instructions, price, reviews about the drug. But first you need to consider its composition and properties. As the name suggests, the medicine comes in the form of an ointment. white with a homogeneous consistency. It is packaged in aluminum tubes of 3 or 15 g. The kit also includes a plastic tip, which makes its use more convenient.
Main active substance The antibiotic mupirocin is Naturally, there are also some excipients, including soft white paraffin, macrogol and softisan.
What properties does the drug have?
In modern medical practice Bactroban nasal ointment is often used. Reviews from experts, as well as relevant studies, have shown that the drug has pronounced antibacterial activity. Basic active ingredient medicine is an antibiotic wide range impact. It is active against staphylococci, streptococci, E. coli and some other microorganisms.
When used externally, the components of the ointment practically do not penetrate into the deep layers of the skin. Entry into the systemic bloodstream is possible only when treating large areas. Drug metabolites are excreted by the kidneys.
When is it appropriate to take the medicine?
In what cases do doctors prescribe Bactroban ointment to patients? The use of the drug is advisable for the treatment of infectious lesions of the tissues of the nasal passages, which are caused by microorganisms sensitive to the antibiotic.
On the other hand, the medicine also copes with a host of other problems. It is often used to treat impetigo, folliculitis, and external furunculosis. ear canals And ears. "Bactroban" can be used as a prophylactic in the presence of wounds, abrasions and cuts in the nasal passages.
The drug "Bactroban" (nasal ointment): instructions and recommendations
Should not be used this remedy on one's own. Only a doctor can prescribe and determine the exact dose of Bactroban (nasal ointment). The instructions contain only some recommendations.
First, squeeze 30 mg of ointment (about the size of a match head) onto a plastic tip and apply to the mucous membrane of the nasal passage. The same procedure should be done with the adjacent nasal passage, after which you should tightly pinch your nose for several minutes - this will help the drug to be evenly distributed throughout the tissues. It is recommended to perform this procedure twice a day. The course of treatment lasts from three to five days. The maximum duration of use of the ointment should not exceed ten days.
After each contact with the ointment, you should wash your hands thoroughly. If the drug accidentally gets on the mucous membrane of the eye, you need to rinse it as quickly as possible using large number warm water.
Are there any contraindications?
Of course, many patients are interested in questions about whether Bactroban nasal ointment has any restrictions on its use. Reviews from doctors, as well as scientific research, indicate that most people tolerate this medicine. Perhaps the only contraindication is hypersensitivity to mupirocin or any other component.
Special studies have not been conducted to study the effect of the drug on the body of a pregnant woman and the fetus. However, since the medicine practically does not penetrate into the systemic circulation, its use is possible, but only on the recommendation of the attending physician and under close supervision.
Bactroban ointment has no age restrictions. It can be used to treat children starting from the first month of life.
Description of possible side effects
Given medicine rarely causes any side effects. Occasionally, during the use of the ointment, local allergic reactions develop, which are manifested by redness and swelling of the tissues, as well as itching and a burning sensation in the area of application. An allergic rash may appear in and around the area where the ointment is applied. It is extremely rare that therapy causes the development of contact dermatitis and erythema. Generalized allergic reactions have also been reported, but these are isolated cases.
If, after applying the medicine, you feel a strong burning and itching that does not go away within a few minutes, the ointment should be quickly removed with a swab, and then rinse the nasal passages. Next, it is recommended to consult a doctor to prescribe another antibacterial agent.
The drug "Bactroban" (nasal ointment): price and analogues
It is quite natural that for many patients important criterion When purchasing a particular medicine, its cost is important. So how much does a tube of ointment cost? The cost, naturally, will depend on many factors, including the manufacturer, city of residence, pricing policy of the pharmacy, etc. The price of one tube with 3 g of medicine ranges from 400 to 600 rubles.
This medicine has no direct analogues. Drugs such as Isofra, Luffel, and Fluimarin can be considered similar in their mechanism of action. In any case, only a doctor can choose a substitute.
Bactroban is an antibiotic-containing ointment for external and local (in ENT practice) use.
Release form and composition
You are given Bactroban in two forms:
- Nasal ointment 2%. The color is white or almost white, of uniform consistency. 1 g of the drug contains 21.5 mg of mupirocin calcium, which is equivalent to 20 mg of mupirocin. The following excipients are used: white soft paraffin, softizan. Packaged in aluminum tubes of 3 g, complete with plastic tip, packaging – cardboard box;
- Ointment for external use 2%. The color is white or almost white, of uniform consistency. 1 g of medication contains 22 mg of mupirocin. Excipients – macrogol 400 and macrogol 3350. Packaged in aluminum tubes of 15 g, complete with plastic tip, packaging – cardboard box.
Indications for use
The use of nasal ointment is practiced for local infections of the nasal cavity caused by Staphylococcus aureus microorganisms (including methicillin-resistant strains) sensitive to mupirocin.
Ointment for external use Bactroban, according to the instructions, is recommended in the following cases:
- Treatment of primary skin infections - folliculitis, impetigo, ecthyma, furunculosis (including boils of the auricles and external auditory canals);
- Treatment of secondary skin infections - infected eczema, injuries, abrasions, insect bites, minor burns and wounds that do not require hospitalization;
- Prevention of bacterial infections in small wounds and cuts.
Contraindications
The use of Bactroban, according to the instructions, is contraindicated in the case of hypersensitivity to mupirocin, and/or to auxiliary components medicine.
The ointment is used with caution for external use on large surfaces of the skin, with increased absorption of polyethylene glycol (through wounds or other damage to the epidermis) in patients with moderate to severe renal failure. Since macrogol ( excipient drug for external use) – polyethylene glycol, which is excreted from the body through the kidneys.
Data on the use of ointment during pregnancy and during breastfeeding No. Therefore, treatment with Bactroban is recommended only under the supervision of a doctor, if possible risk for the child is insignificant in comparison with the benefits of therapy for his mother.
Directions for use and dosage
To apply Bactroban nasal ointment, you should use a special applicator - a reusable plastic tip.
About 30 mg of the product (the size of a match head) should be squeezed into each nostril, after which the nasal passages should be squeezed tightly so that it is evenly distributed throughout the mucous membrane. Repeat the procedure twice a day, the course duration is from 3 to 5 days.
Bactroban ointment for external use is distributed in small quantities onto the affected areas of the skin 2 to 3 times a day; a bandage may be applied on top. The duration of therapy can be up to 10 days, but if after a five-day course there is no effect, it is necessary to take into account the dynamics clinical indicators and re-evaluate treatment tactics.
Fundamental clinical studies were conducted on the safety and effectiveness of using Bactroban ointment in children from two months. Based on the results of observations, no age restrictions have been established.
Correction of the dosage regimen is not necessary for elderly patients, as well as patients with impaired liver function.
Side effects
Therapy with Bactroban nasal ointment may cause allergic manifestations on the nasal mucosa (uncommon); local hypersensitivity reactions (very rare).
When applying Bactroban ointment for external use, the following are possible: itching and burning in the area of application, contact dermatitis, erythrema, allergic rash, swelling, dry skin, in isolated cases - a generalized allergic reaction.
Special instructions
You should avoid getting Bactroban ointment in your eyes, and if this happens, you should rinse them with plenty of water to completely remove the drug.
Ointment for external use should not be applied to drainage areas or mucous membranes.
When allergic symptoms occur skin reactions or significant irritation of the epidermis, you should stop therapy, remove any remaining ointment by rinsing with water, and consult a doctor to prescribe alternative antibiotic drugs.
Long-term use of mupirocin can cause excessive growth of microorganisms that are insensitive to this antibiotic.
There were no cases of negative impact of the use of the product on management complex mechanisms and driving vehicles.
After each contact with Bactroban ointment, be sure to wash your hands thoroughly.
Analogues
Preparations for external use, the main active ingredient of which is mupirocin - Supirocin, Bonderm
Analogs similar to Bactroban ointment for external use according to the mechanism of action, belonging to the same pharmaceutical industry. subgroup - Baneocin, Heliomycin, Gentamicin, Levovinisol, Levomycetin, Linkomycin, Neomycin, Syntomycin, Fuzidin, Fuzimet, Fusiderm, etc.
Bactroban nasal ointment has no direct analogues. Drugs similar in mechanism of action - Aqua Maris, Aqua-Rinosol, Aflubin-Naze, Isofra, Luffel, Marimer, Pinosol, Rizosin, Physiomer, Fluimarin, Evamenol, Nazol Aqua
Terms and conditions of storage
Tubes of ointment should be stored in a place inaccessible to children, at a temperature not exceeding 25° C.
The shelf life of the ointment for external use is 2 years, for nasal use – 3 years.
Bactroban is antimicrobial drug For local application.
Pharmacological action
Bactroban contains mupirocin, a broad-spectrum antibiotic that was developed specifically for external use. Mupirocin inhibits the increase in the amount of protein in bacterial cells, has a bacteriostatic and, subject to increasing its dose, a bactericidal effect.
The studies did not reveal cross-resistance between mupirocin and other antimicrobial agents.
Bactroban is active against some staphylococci, streptococci, meningococci, diplococci of the genus Neisseria, causing gonorrhea, Haemophilus influenzae, pathogens of opportunistic infections, infections of the mucous membranes, respiratory, intestinal, urogenital purulent-inflammatory diseases, Enterobacter, pertussis, some types of Proteus, Citrobacter.
Release form
Bactobran ointment and cream for topical use are available. Bactroban nasal is also produced for local treatment nasal cavity infections.
Indications for use
According to the instructions, Bactroban is used for treatment bacterial infections soft tissues and skin, folliculitis, furunculosis, impetigo, nasal infections.
Bactroban ointment and cream can be used externally in complex therapy and monotherapy, but with the condition that no other drugs will be applied to the skin at the same time. If this is still necessary, an interval of half an hour should be maintained.
Instructions for use of Bactroban
Bactroban cream is applied using a cotton swab or gauze up to three times a day to the affected area of the skin, which should be cleaned before applying Bactroban. A bandage can be applied over the affected and treated area.
The duration of treatment and the regimen for using Bactroban are determined by the doctor, but the instructions for Bactroban indicate that the average duration of the course of treatment is 7-10 days.
After using Bactroban cream, you should wash your hands thoroughly and avoid getting it in your eyes.
For patients with impaired renal function, no dose adjustment of Bactroban is required.
When using Bactroban cream, it should be remembered that systemic absorption of the drug increases when the integrity of the skin is damaged.
Bactroban ointment is applied thin layer on the cleaned area of skin one to three times a day, after which you can apply a bandage.
After treating the skin with Bactroban ointment, you should wash your hands thoroughly and avoid getting it into your eyes.
The course of treatment indicated in the Bactroban instructions is from a week to 10 days.
Bactroban nasal is placed in a small amount into each nostril two times a day. The recommended course of treatment is five days.
The Bactroban instructions indicate that after applying the ointment intranasally, in order for it to be better distributed, you need to close your nose well with your fingers, press its wings on both sides several times and rub gently. On the third to fifth day of the treatment course, the nasal cavity is freed from infectious agents.
Patients with renal liver failure The dose of nasal Bactroban does not need to be adjusted.
Side effects
Bactroban is usually well tolerated, but isolated cases of itching, burning, dry skin, hyperemia, urticaria, eczema, and erythema have been reported.
Rarely, but possible, the appearance of nausea, pain in the epigastric region, secondary infection of wounds, ulcerative stomatitis, headaches, and systemic allergic manifestations.
Contraindications
According to the instructions, Bactroban is not prescribed to patients who are intolerant to mupirocin and other components of the drug.
It is prohibited to use Bactroban cream and ointment intranasally and in ophthalmology.
Bactroban should be prescribed with caution to elderly patients and those with impaired renal function, especially if treatment with cream or ointment is to be done large plot skin or skin with damaged integrity.
Bactroban ointment is not prescribed for children under two years of age, and cream for children under one year of age.
Bactroban cream and ointment are prescribed for pregnant women and during breastfeeding only in isolated cases, but treatment of cracked nipples during lactation is allowed. Immediately before feeding, you should wash off any remaining ointment under running water using soap.
Bactroban nasal is usually prescribed to children over 12 years of age, since no studies have been conducted on the effect of the drug on children over younger age. There is no data on the possibility of using nasal Bactroban in pregnant women. It is only known that the drug is not excreted into breast milk.
Bactroban nasal does not affect the ability to control transport and complex mechanisms.
Manufacturer: Glaxo Operetaions UK Limited (Glaxo Operations UK Limited) Great Britain
ATS code: R01AX06
Farm group:
Release form: Soft dosage forms. Ointment.
Indications for use:
General characteristics. Compound:
Active ingredient: mupirocin calcium 21.5 mg, which corresponds to the content of mupirocin 20 mg
Excipients: white soft paraffin - 929.6 mg, softizan 649 - 48.9 mg.
3 g - aluminum (1) with a plastic tip - cardboard packs.
Pharmacological properties:
Mupirocin - antibiotic local action. Mupirocin inhibits isoleucyl transfer RNA synthetase, disrupting protein synthesis in bacterial cell. Due to specific mechanism action and unique chemical structure, mupirocin does not show cross-resistance with other antibiotics. At correct use mupirocin, the risk of the emergence of resistant strains of microorganisms is small. When used in minimal inhibitory concentrations, mupirocin has bacteriostatic properties, and when used in higher concentrations, it has bactericidal properties.
Antibacterial activity: in vitro effective against Staphylococcus aureus(including methicillin-resistant strains), Staphylococcus epidermidis, Streptococcus spp. and also against gram-negative microorganisms: Haemophilis influenzae and Escherichia coli. Other gram-negative microorganisms are less sensitive, and strains of Pseudomonas aeruginosa are resistant to mupirocin.
Efficacy against the listed microorganisms has been clinically confirmed.
Pharmacokinetics. Mupirocin after intranasal use enters the systemic circulation when used in newborns and premature infants, without causing any unwanted effects, indicating intolerance to the drug. Absorption of mupirocin through the mucosa (less than 1% of the applied dose is excreted by the kidneys in the form of monic acid).
Indications for use:
- local infections of the nasal cavity caused by microorganisms sensitive to mupirocin, including carriage of Staphylococcus aureus (including methicillin-resistant strains).
Directions for use and dosage:
The ointment is applied using an applicator (reusable tube). After treating the surface of the mucous membrane, the nasal passages should be tightly compressed, which ensures uniform distribution of the ointment throughout the nasal mucosa.
The course of treatment is 3-5 days. The drug should not be used for more than 10 days without reassessing the condition. Should not be mixed with others medicines for intranasal use to avoid dilution of the ointment and, consequently, a decrease in antibacterial activity or a possible change in the stability of the intranasal ointment.
Apply a small amount of ointment, approximately the size of a match head (approximately 30 mg ointment), into each nostril for 5 days.
Features of application:
Avoid contact with eyes. In case of contact with eyes, rinse with plenty of water until complete removal leftover ointment.
Impact on the ability to drive vehicles and operate machinery
No negative effects on these functions were detected.
Side effects:
At 12 clinical studies the frequency of adverse reactions was less than 0.1%. There have been isolated reports of adverse reactions (<1/10 000) во время рутинного применения препарата и указанная частота связана скорее с частотой сообщений, нежели с частотой развития реакции.
Adverse reactions by organ and system are listed below, indicating the frequency of their occurrence. Frequency determination: very often (>1/10), often (>1/100, but<1/10), нечасто (>1/1000, but<1/100), редко (>1/10,000, but<1/1000), очень редко (<1/10 000).
From the immune system: very rarely - local hypersensitivity reactions.
From the respiratory tract: rarely - allergic reactions from the mucous membrane.
Interaction with other drugs:
Not noted.
Contraindications:
- known hypersensitivity to any of the components of the drug.
Use of the drug BACTROBAN® nasal ointment during pregnancy and breastfeeding.
There are no data on the use of the drug during pregnancy and lactation. However, preclinical data from studying the drug did not reveal a negative effect on pregnancy or embryonic development.
Overdose:
To date, there have been no reports of drug overdose.
Storage conditions:
The drug should be stored at a temperature not exceeding 25 ° C out of the reach of children. Shelf life - 3 years. Do not take the drug after the expiration date indicated on the package.
What is Bactroban ointment intended for? Instructions for using this drug will be presented a little further. We will also tell you about the composition of the product we are considering, what indications it has, and also touch on whether there are side effects and contraindications.
Form of the medicinal product and its composition
In what form can you buy Bactroban ointment? The instructions for use state that this drug is sold in two different forms:
- 2% product for external use. 1 g of this drug contains 20 mg of mupirocin. It goes on sale in 15 g tubes, which are placed in a cardboard box.
- 2% product for nasal use. 1 g of this drug contains 20 mg of mupirocin. It goes on sale in 3 g tubes, which are placed in a cardboard box.
Pharmacological characteristics of the drug
What is Bactroban (ointment)? This drug is a good antibiotic. It should be noted that it has a fairly wide spectrum of action. This ointment is active against many gram-negative and gram-positive bacteria that cause the development of various skin infections.
The principle of action of the medication
How does Bactroban ointment work? The instructions for this medication state that its active substance inhibits protein synthesis in the bacterial cell through reversible binding to isoleucyl RNA synthetase. As a result of this effect, the process of incorporation of isoleucine into protein chains being built is prevented. 
At minimal inhibitory concentrations, the active element of the drug has a bacteriostatic effect. If you use the ointment in higher concentrations, you can expect a bactericidal effect.
Due to the specific mechanism of action, as well as the unique chemical structure, cross-resistance with other antibiotics is completely absent. If the ointment is used correctly, the likelihood of the emergence of resistant strains of microorganisms is small.
Pharmacokinetics of the drug
Is Bactroban ointment absorbed into the systemic circulation? The instructions for this product state that the active element of the drug practically does not penetrate the skin. But this is only if they were not damaged.
If absorption of the drug does occur (for example, through damaged skin), mupirocin is first metabolized to an inactive metabolite (i.e., monic acid), and then quickly eliminated from the body through the kidneys.
Instructions for use of the nasal drug "Bactroban"
Nasal ointment, the instructions for which will be discussed right now, is used 2-3 times a day. To do this, the medicine (in a small amount) is applied to the little finger and then injected into one of the nostrils. The other nasal passage is lubricated in exactly the same way. After this, both nostrils are closed on both sides using fingers. This action promotes uniform distribution of the drug inside the nasal passages. 
How long should Bactroban be used? Nasal ointment, the instructions for which are presented above, is used for 5-7 days. However, dosage regimens for adults and children are no different. However, it is recommended that the drug be administered to infants using cotton swabs or a gauze swab.
Bactroban ointment: external use
Ointment for external use is used 2 or 3 times a day. To do this, a small amount of the drug is applied to the affected area of the skin. In this case, it is recommended to apply a gauze bandage on top.
We talked above about how long you can use Bactroban ointment for the nose. As for the external agent, the duration of therapy with this drug should be no more than 10 days. The treatment period depends on the severity of the skin lesion.
If there is no therapeutic effect after 5 days, then the doctor is advised to reconsider further treatment tactics. In this case, it is necessary to take into account all the dynamics of clinical indicators.
Special use of the drug
What do you need to know before using Bactroban? Nasal and external ointment can be used for children of any age (from 2 months). 
Patients with impaired liver function, as well as elderly people, do not require adjustment of the dosage regimen.
It should also be said that after applying the medicine to the skin, you should wash your hands thoroughly.
Indications for use of the medication
According to the instructions that are attached to the drug we are considering, this medication should be used only for the following pathological conditions:
- For the treatment of primary skin infections (for example, folliculitis, ecthyma, impetigo and furunculosis, including boils of the auricle and external auditory canal).
- For the treatment of secondary skin infections (for example, infected eczema, infected trauma (abrasions, insect bites), as well as minor (not requiring hospitalization) wounds and burns).
- To prevent bacterial infections, as well as complications that arise due to minor cuts and wounds.
Contraindications to the use of the medication
The only contraindications for this drug include hypersensitivity to its main components. It should also be noted that the active substance of the medication we are considering can be easily absorbed into the systemic bloodstream through the wound surface, as well as through other skin lesions. In this case, the active element is excreted only through the kidneys. 
It should also be said that mupirocin-based ointment is strictly prohibited for use on large surfaces, as well as in conditions that are accompanied by increased absorption of polyethylene glycol. As a rule, this happens with severe and moderate renal failure.
Special instructions for the use of the medical product
Before using the ointment we are considering, you should definitely consult a doctor and carefully study the attached instructions.
I would like to especially note that ointment for external use should under no circumstances be used in ophthalmology. It is also strictly forbidden to administer it intranasally. To do this, you need to use a different type of drug.
When applying the ointment to the skin of the face, it is necessary to avoid contact with mucous membranes and eyes. If this does happen, the visual organs should be immediately rinsed with plenty of warm water.
The active substance of the drug can be absorbed from damaged skin and open wounds, and then excreted by the kidneys. In this regard, this drug should be used with extreme caution in the presence of moderate or severe renal impairment.
In rare cases, after using the ointment we are considering, the patient may experience allergic reactions or significant irritation of the skin. To get rid of unpleasant symptoms, treatment with this drug must be stopped immediately. In this case, the affected area of the skin must be immediately washed with warm water (to remove any remaining ointment). After this, you should consult your doctor again, who must prescribe you alternative antibacterial treatment.
As with other antimicrobial agents, using the ointment for too long may result in increased growth of non-susceptible microorganisms. 
To date, no negative effects of the drug on the ability to drive a car or the efficiency of working with various mechanisms have been observed.
Side effects
Like any medicine, Bactroban ointment has some side effects. After using the drug, a small number of patients experienced a feeling of tingling, burning and itching at the site of application. Those who used the intranasal form of the drug sometimes developed rhinitis.
If these signs appear, you should immediately stop using the drug and seek help from a doctor.
Overdose
To date, no cases of overdose with Bactroban ointment have been observed. But this does not mean that this medication can be used uncontrolled and without prior consultation with a doctor.
Price of the medicine and reviews about it
After a doctor prescribes this drug, many patients are concerned about how much it costs. It should be noted that the price of this product is quite high. For ointment for external use you will have to pay about 430 Russian rubles. As for the nasal drug, it costs a little less.
In general, treatment with this drug is not very expensive, since the course of therapy lasts no more than 7-10 days.
What do they say about Bactroban ointment? Patients note that this drug copes with the task perfectly. It treats both primary and secondary skin infections well, and also prevents their recurrence. However, it should be noted that with prolonged use, this medication acts weaker and weaker. This is due to the fact that with long-term use the drug leads to increased growth of insensitive microorganisms. That is why it should be used strictly according to the prescription of the attending physician. 
Drug analogues
Today, almost all medicines have analogues. And Bactroban ointment is no exception. You can replace this drug with the following medications: Bonderm, Supirocin or Mupirocin. However, I would like to say right away that the principles of using these products differ significantly from the method of using Bactroban ointment. That is why it is necessary to consult your doctor first.