Erythromycin ointment for newborns. Eye ointment with erythromycin: instructions for use

Erythromycin was obtained back in the 50s of the last century, and is the very first in the group of macrolide antibiotics. He showed good efficiency against entire groups of gram-positive and gram-negative microorganisms. Erythromycin ointment based on it is an antibiotic local action, widely used in ophthalmic practice, as well as for the treatment of skin infections.

Low price, good application results and minimal quantity side effects made erythromycin-based ointments popular among doctors and patients.

Erythromycin ointment is an antibacterial drug, the main component of which is an antibiotic. wide range actions.

Eye ointment

Ophthalmic ointment is used in the treatment of infectious lesions of the conjunctiva of the eyes. Compound:

• erythromycin – 10 thousand units per g;
• sodium disulfite (meta-, pyro-) – 0.0001 g;
• binder – ophthalmic petroleum jelly up to 1g.

The medicine is available in tubes weighing 3, 5, 10 g.

For external use

The medicine is intended to suppress skin infections. Its components are:

1. erythromycin – 1.11g;
2. sodium disulfite (metabisulfate) – 0.01 g;
3. nipazole – 0.12 g;
4. lanolin – 40 g;
5. Vaseline – up to 100 g.

The drug is packaged in tubes of 15 g.

Both forms of the drug look like a homogeneous yellow-brown substance.

Attention: Erythromycin is considered one of the most safe antibiotics, is a reserve of Penicillin.

Indications for use

The active substance of the drug belongs to the class of macrolides. This provides a bacteriostatic effect when used - disruption of peptide bonds in the structure of microorganisms and suppression of the synthesis of new proteins of pathogenic flora. Large doses lead to a bactericidal effect - microorganisms die.

Erythromycin does this effective means against the following types microorganisms:

• staphylococci;
• streptococci;
• chlamydia;
• gonorrhea and hemophilus influenzae.

The drug is ineffective against some classes of gram-negative bacilli, therefore, when prescribed, a culture test for sensitivity to antibiotics is often done.

The ophthalmic form of the antibiotic is used for the following diseases:

1. conjunctivitis (inflammation of the mucous membrane of the eyes) of various etiologies;
2. keratitis;
3. blepharitis;
4. trachoma;
5. blepharitis, for the prevention of blenorrhea in newborns.

Erythromycin interacts well with the watery surface of the mucosa and enters the cornea. Suction efficiency up to 60%. Penetrates into all body fluids and decomposes in the liver. It is well excreted by the kidneys and gastrointestinal tract.

Medicine for external use helps to overcome bacterial infections with the growth of pathogenic flora on the skin. It is used in the treatment of the following conditions:

• pustular diseases of soft tissues;
• infected wounds;
• burn lesions of II-III degree;
• trophic ulcers;
• acne in adolescence;
• bedsores.

An indispensable condition for use is infection of the skin. In its absence, the antibiotic is not used. Erythromycin nasal ointment is used to prevent the proliferation of adenoids during inflammation of the mucous membranes of the nasopharynx and runny nose.

The drug is not used in the treatment of viral pathologies - herpes, chickenpox and other infections.

Erythromycin ointment - instructions for use

Before using the drug, a smear is taken to determine sensitivity to erythromycin. The dose and number of applications suggested in the instructions for use of Erythromycin ointment should not be exceeded. If the drug is active against the pathogen, the infection will be eliminated.

Eye ointment

The drug is placed behind the lower eyelid three times a day. To do this, squeeze out 1-1.3 cm of cream. In most cases, the course of treatment is up to 14 days.

For trachoma and chlamydia infection, 4-5 medications are applied per day. The course of treatment lasts up to 3-4 months.

You cannot wash the remaining drug out of your eyes; you need to wait until it is completely dissolved and your vision clears.

Product for external use

Erythromycin is applied to clean, dry skin 2-3 times a day. thin layer. The duration of treatment is 1-2 months.

When treating burn wounds, the medicine is applied 2-3 times a week.

During pregnancy

Erythromycin ointment is not recommended for use during pregnancy. The drug enters the systemic circulation and is metabolized in the liver. Treatment can be recommended only if it is impossible to overcome the infection in another way.

It is especially dangerous in the initial third of the term. When used during lactation, feeding must be stopped. The decision to prescribe is made by the doctor in each case individually, according to indications.

For children

Instructions for use allow the use of Erythromycin eye ointment for children from the first days of life. The antibiotic is considered to have low toxicity compared to other drugs, in particular penicillin.

Erythromycin ointment treats infections caused by movement along the birth canal. These may be skin infections or conjunctivitis. In this case, an ophthalmic or cutaneous version of the drug is selected. The mother should put the medicine into the conjunctival sac of the child’s eyes according to the proposed scheme. The drug can be used only after consultation with a pediatrician or ophthalmologist.

If there is a danger of the appearance of blenorrhea, the newborn is given a single application of the drug measuring 0.5-1 cm in each eye.

Attention: erythromycin ointment for external use is used only for bacterial infections. To relieve irritation from diapers and for hives, other remedies without antibiotics are sufficient.

Contraindications

Treatment with antibiotics requires strict adherence to the regimen and course of administration. Erythromycin ointment is prescribed by a doctor. It is not recommended:

• with individual intolerance;
• when severe lesions liver, with jaundice;

The drug should be used with caution during pregnancy, in old age, and in the presence of liver disease.

Side effects

The use of the medicine may cause local reactions. After applying Erythromycin ophthalmic ointment, the following are possible:

1. increased hyperemia;
2. burning on the mucous membrane;
3. loss of clarity of vision;
4. allergic manifestations.

A product for external use, in addition to allergic reactions, can cause itching, peeling of the epidermis, and swelling of the skin.

additional information

Preparations containing erythromycin are not used simultaneously with the following medications:

• chloramphenicol;
• clindamycin;
• lincomycin.

When using skin exfoliants, it is possible that negative reactions on the epidermis may increase after using Erythromycin.

Treatment with the drug reduces the effectiveness of the use of other antibiotics:

1. penicillins;
2. carbapenems;
3. cephalosporins.

In parallel treatment of acne by different means you need to maintain an hour interval between applying the drugs. If there is no improvement, the course of treatment of the rash with Erythromycin can be extended to 2-3 months.

With prolonged use, superinfection may occur.

Analogues

There are no other external preparations containing erythromycin as an active substance. The closest analogue is . Differences and features of use:

• Tetracycline is a drug from another group. Its concentration in drugs is higher (up to 3%), so they are used to treat complicated and more voluminous lesions.
• Not used for small children (only from 10 years old).
• More side effects and complications from use.

The cost of Tetracycline ointment is from 50 rubles.

Other analogues of ophthalmic ointment Erythromycin - Ciplox.

For external use for purulent lesions, Dalacin can be used.

Erythromycin ointment for acne is an antibiotic external remedy containing as a therapeutic substance an antibiotic from the macrolide group, which has high activity in the treatment of skin and tissue infections.

Unlike penicillin, erythromycin is better tolerated by patients and is less likely to provoke allergic and other unwanted side reactions.

The medicine contains 10,000 units of active substance in 1 gram and gives a high therapeutic result in getting rid of acne and acne. Erythromycin destroys the main pyogenic bacteria that cause inflammation and suppuration in the hair follicle area.

The main medicinal ingredient blocks the production of protein compounds from propionibacteria acne and Staphylococcus epidermidis.

These pathogenic microorganisms are able to multiply on the skin and, with weakened local immunity and abnormally high production of sebum (sebum), lead to the appearance of various kinds of acne and pustules.

To treat acne, the ointment is applied pointwise to areas of inflammation and suppuration three times a day, after pre-treating the affected areas with hydrogen peroxide and drying. The duration of applications varies depending on the severity of the process and the patient's sensitivity to Propionibacterium acnes and S. epidermidis.

It should be remembered that microbial flora resistance to erythromycin develops quite quickly, so use of the drug for longer than 1 to 2 months is not recommended.

In case of boils development, Erythromycin ointment is used after the abscess has matured and opened to destroy the pathogenic flora in the area of ​​purulent masses and prevent re-suppuration.

1. Features of application.
2. When using the ointment simultaneously with another anti-acne agent, the interval between applications should be at least 1 to 2 hours.
3. If during treatment for 3-4 weeks there are no positive changes in the condition of the skin due to acne and pimples, you should consult a dermatologist.
4. To obtain a noticeable therapeutic result, if there is no addiction to the product, it may take 2 to 3 months.
5. During the treatment of acne and pustular rashes, it is not allowed to use the drug while cleansing the skin with abrasive or highly active chemicals(scrubs, peelings). This leads to excessive irritation and inflammation of the epidermis.
6. With the simultaneous use of ointment and external pharmaceutical products that cause peeling, the development of excessive dryness of the skin and irritation is likely.
7. Erythromycin ointment is incompatible with external preparations containing aminoglycosides (Baneocin, Gentamicin ointment), Lincomycin, Clindamycin, Chloramphenicol (Syntomycin emulsion). The product reduces the bactericidal effect of external ointments with penicillin, cephalosporins, and carbapenems.

Eye ointment

Erythromycin-based ointment is actively used in ophthalmology for the treatment of infectious pathologies eyes of bacterial origin - more often when affected by streptococcus, chlamydia, staphylococcus. They use Erythromycin ophthalmic ointment in tubes of 3, 7 and 10 grams, and not a product for external use.

Eye ointment is prescribed as a single drug (independent drug) for the treatment of the following diseases of the organs of vision:

• bacterial blepharitis (inflammation of the eyelids);
• purulent conjunctivitis and blepharoconjunctivitis;
• ophthalmia of newborns, including gonoblenorrhea (occurs in infants when passing through birth canal, infected with gonococci, Haemophilus influenzae, Trichomonas, chlamydia);
• chalazion (painless, dense tumor in the area sebaceous gland in the century);
• barley (meibomite) – purulent inflammation sebaceous gland;
• endophthalmitis (purulent-inflammatory process inner shells eyeball);
• ophthalmochlamydia and trachoma;
• keratitis (inflammation of the cornea).
• secondary infection after ophthalmic surgery.

Fungi and viruses are resistant to erythromycin, so, for example, if conjunctivitis of a viral nature has developed, the ointment will not have any effect on the pathology. For this reason, the treatment composition can be applied only after consultation with an ophthalmologist and an accurate diagnosis of a bacterial rather than a viral or fungal infection.

In case of boils development, Erythromycin ointment is used after the abscess has matured and opened to destroy the pathogenic flora in the area of ​​purulent masses and prevent re-suppuration.

1. When treating blepharoconjunctivitis, ophthalmia of newborns, keratitis, meibomitis, chalazion, eye ointment is applied to the conjunctiva of the eye in the form of a strip, slightly retracting the lower eyelid, at a dose of 200 - 300 mg 3 times a day.
2. To prevent the development of ophthalmia in children after birth, use the ointment once, placing a strip of the product no more than 5–10 mm long behind the baby’s lower eyelid. When using the toilet, a newborn should not be washed remedy from the eyes.
3. The duration of use of eye ointment for major infectious lesions of the organs of vision, including keratitis, is determined by the attending physician, taking into account the form and severity of the pathology, age and concomitant diseases of the patient. The maximum duration of treatment is limited to 2 weeks.
4. When treating chlamydial conjunctivitis and trachoma, the product is placed behind the eyelid at least 4 to 5 times a day. In this case, the ophthalmologist performs a mandatory autopsy of the follicles. When the severity of inflammatory phenomena decreases, the number of ointment applications is reduced to 2–3 times a day. The duration of treatment for these eye infections increases to 3–4 months.
5. For blepharoconjunctivitis, trachoma, ophthalmochlamydia, ophthalmia of newborns, the conjunctiva of both eyes is treated with ointment, since the infection quickly spreads to the healthy organ of vision.

Skin ointment

Erythromycin ointment for external use shows a high therapeutic result for infectious skin and soft tissue lesions caused by bacterial organisms resistant to penicillin, tetracycline, streptomycin and chloramphenicol.

The ointment suppresses the vital activity of gram-positive bacteria: staphylococcus, streptococcus, anthrax bacillus - the causative agent anthrax, causing necrotic cutaneous ulcers, gonococcus, clostridia (gas gangrene), corynebacteria - the causative agents of diphtheria and ulcerative skin lesions.

The product has a bactericidal and antimicrobial effect in the following pathologies:

• infected purulent wounds;
• pustular lesions, including furunculosis, secondary infection in eczema, streptococcal and staphylococcal impetigo;
• trophic ulcers;
• bedsores;
• damage to the epidermis with the addition of a bacterial infection.

The medicinal product is applied to the affected areas in a thin layer, without rubbing, 2 - 3 times a day after removing the purulent masses and treating with hydrogen peroxide.

In case of burns, use is reduced to 2–3 applications per week.

The duration of treatment for the patient is determined by the attending physician, taking into account the type of pathogen, the form and specificity of the disease, and the severity of the process. The average duration is from 7 days to 2 – 3 weeks. In rare cases, therapy is extended to 6–8 weeks.

Features of therapy.

1. The medication is not prescribed if there is no process of suppuration, and also if skin affected by mycobacterial and fungal infections. She won't give therapeutic effect. Therefore, before using the product, it is recommended to clarify the diagnosis and check the sensitivity of microorganisms to erythromycin.
2. With prolonged use of Erythromycin ointment, its degree may decrease. therapeutic effects due to the development of resistance to erythromycin in pathogenic bacteria.

Erythromycin ointment in gynecology

In the field of gynecology, the drug under discussion is used as an external agent in complex therapy:

• chlamydia, including chlamydia in pregnant women;
• inflammation of the mucous membrane of the external genitalia, including colpitis, vulvitis;
• gonorrhea and syphilis at an early stage.

During treatment, the ointment is applied to the skin and mucous membrane of the vulva up to 3 times a day after a thorough hygienic toilet using Chlorhexidine, Miramistin, and furatsilin solution. Gauze tampons thickly soaked in ointment are inserted inside, changing them after 6 hours. The duration of therapy is determined by the gynecologist.

In case of boils development, Erythromycin ointment is used after the abscess has matured and opened to destroy the pathogenic flora in the area of ​​purulent masses and prevent re-suppuration.

1. Before starting treatment, it is recommended to conduct smear tests to identify the causative agent of the disease.
2. It is allowed to start therapy without waiting for test results and an antibiogram, and to adjust treatment after receiving them by continuing to use the ointment or replacing it with another medication.
3. Taking into account the identified pathogenic organisms, determine the need to use Erythromycin ointment. The product will help with the following pathogens: gonococci, chlamydia, staphylococci, streptococci, spirochetes.

Erythromycin ointment during pregnancy

Unlike Erythromycin, which is used orally, the properties of the ointment allow it to be used as an external remedy for women awaiting replenishment.

For pregnant women, this remedy is prescribed by an ophthalmologist for eye chlamydia and other pathologies, a dermatologist for skin problems, or a gynecologist for the treatment of urogenital diseases that worsen during this important period of their life.

Although antibiotics are extremely undesirable during pregnancy, Erythromycin ointment does not have any effect during pregnancy. overall influence neither on the mother’s body, nor on the course of gestation and development of the embryo.

This pharmaceutical product does not systemically affect the body, however, in order to avoid unpredictable consequences, you should obtain permission from a gynecologist.

Erythromycin ointment for children

The advantages of Erythromycin ointment include extremely low absorption into the blood and local effect on diseased areas.

Therefore, the medicine in the form of an ointment is used even to treat infants, but only after examination by a specialized specialist and pediatrician. When prescribing, the child’s age, the form and severity of the pathology, as well as the child’s allergic status must be taken into account.

In pediatrics, this remedy is one of the few external antibiotic drugs approved for the treatment of:

• chlamydia in newborn girls;
• skin diseases with purulent-inflammatory elements;
• eye diseases, including purulent conjunctivitis, ophthalmochlamydia, blepharitis.

Conditions and shelf life

Temperature range at which Erythromycin ointment retains its properties medicinal properties- from 1 to 20°C. Shelf life - no more than 2 years from the date indicated on the manufacturer's packaging. The product should not be allowed to freeze. Keep out of the reach of children.

How much does Erythromycin ointment cost?

In the Russian pharmacy chain, Erythromycin ointment can be purchased at prices ranging from 75 to 85 rubles, depending on the volume of the tube.

Side effects

When used topically, the absorption of erythromycin into the blood is very low, so the ointment does not cause any general side effects. The minimal amount that enters the bloodstream is processed by liver enzymes and excreted in urine and feces.

Of the rare adverse reactions During treatment with Erythromycin ointment, people allergic to erythromycin experience slight redness in the application area, burning, itching, and dryness. If these phenomena do not go away within 2 days, but become more pronounced, the use of the ointment should be discontinued.

When using eye ointment, unwanted side effects in the form of local reactions are possible:

• redness of the sclera, burning, irritation of the conjunctiva;
• blurred visual perception;
• increased lacrimation.

Such reactions usually subside within half an hour after applying the ointment. If allergic phenomena last longer than 1–2 days, treatment is suspended and contact an ophthalmologist.

With long-term and uncontrolled therapy gynecological diseases, the development of candidiasis (thrush) is possible.

With prolonged treatment of skin pathologies, a secondary superinfection can develop - a severe, rapid form of infection with erythromycin-resistant microorganisms that have not previously manifested themselves, against the backdrop of a weakening of local defenses.

Analogues

Close composition and similar therapeutic effect have the following drugs: Lincomycin ointment, Dalacin, Bactroban, Tetracycline ointment, Clindacin, Zinerit.

Erythromycin ointment for children - medical drug for the treatment of eye diseases, used when other diseases caused by pathogenic microorganisms are detected in children. Is mild antibiotic, approved for the treatment of children infancy. The drug is based on erythromycin, a toxin-free antibiotic that does not weaken the child’s body and does not contribute to a decrease in immunity.

An ophthalmologist prescribes erythromycin ointment for children to treat infectious eye diseases that arise due to the active reproduction of pathogenic microorganisms: chlamydia, streptococci, mycoplasmas, ureaplasmas and others.

Eye ointment treats:

• Bacterial blepharitis, blepharoconjunctivitis;
• The occurrence of conjunctivitis in newborns;
• Trachoma;
• Chlamydia;
• Ophthalmia of infants.

The ointment can be used against the following types of microorganisms and infections:

• Gonococci;
• Listeria;
• Corynobacteria;
• Salmonella;
• Mycobacteria;
• Mushrooms;
• Actinomycetes;
• Clostridia;
• Causative agents of diphtheria and whooping cough.

The drug has a pronounced antibacterial effect, prevents the proliferation of microbes and destroys viruses. If you use it in large quantities, a strong bactericidal effect is possible. The main advantage of the drug: it is successfully used by patients suffering from allergies to penicillin drugs. Disadvantage: microorganisms quickly get used to the ointment.

Instructions for use

Erythromycin ointment for children is used strictly according to the instructions written on the package. You should not self-medicate - this can aggravate the situation and lead to irreversible consequences for the child. Eye ointment is used only after appropriate prescription by a doctor. The dosage of the drug is strictly individual for each type of disease. Let's take a closer look at the most common ones.

During treatment:

• Conjunctivitis, blepharitis - at least 3 times a day, the medicine (300 milligrams) is placed under the upper and lower eyelids until completely absorbed. The duration of treatment is two months.
• Trachomas - first the doctor opens the purulent formations that arise from this disease, then the ointment must be placed behind the eyelid five times a day. Treatment of this disease (provided it is started in a timely manner) is quick and without complications.
• – the sore eye is washed with strong brewed black tea, and then the affected area is lubricated with the medicine. Actions are performed until complete recovery.

The instructions are strictly followed, this helps speed up the treatment process and avoid possible negative consequences.

Before applying the medicine to the eyelid, slightly warm the tube of ointment in your hands. Then pull back the eyelid and gently squeeze out a small amount of the drug. Try not to touch the iron base - this can easily introduce germs. Then close your eyes tightly and rotate eyeballs clockwise for 25 seconds. If a stye occurs, you can apply a warm compress to the sore spot. To do this, apply a few drops of ointment to clean, sterile gauze and apply to the affected area.

Side effects

The body of each child and adult is completely individual, and the effect of using ointment to treat eye diseases can vary significantly. There are frequent cases of occurrence side processes, due to the presence of certain chronic diseases in children or individual intolerance to individual components.

If the ointment is used longer than indicated in the instructions, this may lead to resistance of individual microorganisms and viruses to the components of the drug, which threatens reappearance infections.

Ointment for the treatment of eye diseases cannot be used in the following cases:

• Disorders of the kidneys and liver;
• Individual intolerance to the drug;
• Increased sensitivity;
• Pregnancy and lactation period.

The following side effects are possible:

• Dizziness;
• Development of allergic reactions;
• Nausea and vomiting;
• Increased tearing and redness of the eyes;
• Weakness;
• Local irritation;
• Emergence repeated infections due to the resistance of pathogenic organisms to the antibiotic due to prolonged use.

In order to minimize the occurrence of negative reactions, the instructions for use of the drug must be strictly followed, especially when treating conjunctivitis and other diseases in children. There have been no reports of drug overdose at this time.

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Important instructions for those who wear! Whenever inflammatory process or infection, stop wearing it for a while. If the disease does not progress, lenses can be worn for a short time. If you notice that your visual acuity has decreased or there is clouding or redness, consult a doctor immediately! Delay is fraught with serious illness. These recommendations apply to both adults and children. If a child complains of discomfort after applying the ointment, his eyes water and look red, this is also a reason to contact a medical facility.

Analogues and price

Treatment of conjunctivitis can also be carried out with analogues of a mild antibiotic, for example, Ciplox, Dexagentamicin, etc.

Erythromycin ointment is an antagonist of clindamycin, which means it reduces the bactericidal properties of other drugs, especially those containing penicillin. If you use the ointment simultaneously with abrasive preparations, this can lead to dry skin around the eyes, the appearance of discomfort, peeling. It is recommended to use the antibiotic separately from other drugs.

To prevent the occurrence of conjunctivitis and ophthalmia in children, do not wash out the eye ointment. If the mother has a baby, it is recommended to take the ointment together with penicillin preparations.

The drug must be stored in a dark, cool place out of reach of children. The ointment is stored for about 3 years, and its cost in pharmacies rarely exceeds 30 rubles for a small tube. Carefully follow your doctor's advice, follow strict dosage, recommendations, healthy image life and show children to an ophthalmologist in a timely manner. A disease is easier to prevent than to cure.

At the moment, no analogues are produced. Erythromycin ointment is available from different manufacturers, and it is inexpensive.

Other dosage forms: tablets.

Price

average price online*: 43 rub.

Erythromycin-based ointment is also widely used in ophthalmic practice for the treatment infectious diseases mucous membranes of the organs of vision. Eye ointment can be prescribed as the main component drug therapy with the following indications:

• blepharitis of bacterial origin;
• purulent conjunctivitis;
• chalazion;
• barley;
• trachoma;
• chlamydia;
• keratitis, etc.

Note! Using ointment for viral conjunctivitis will be ineffective, so the product can be applied only after consultation with an ophthalmologist.

How to apply?

The ointment is used to treat damaged areas, applying a thin layer. The procedure should be carried out 2-3 times a day (treatment burn surfaces- 2-3 times a week). The duration of use of erythromycin ointment should not exceed 2 months.

Eye ointment is placed behind the lower eyelid of the affected eye 3 times a day. Before applying the composition, it is recommended to perform eye hygiene using a solution of furatsilin or herbal decoction. Treatment of eye infections can be carried out within 14 days.

Note! When treating trachoma, the ointment is applied behind the eyelid 5 times a day (the course of treatment can last up to 3 months). Mandatory procedure During treatment with erythromycin, the purulent follicles are opened, which should be carried out by an experienced doctor.

Contraindications

The ointment has no contraindications for use and can be used by everyone age groups patients. You should remember the possible allergic reactions if you are intolerant to the components of the drug, in this case treatment with erythromycin will be contraindicated.

Pregnancy and lactation

The use of the drug during these periods is permitted if there are indications and it is impossible to carry out therapy using other drugs. The drug does not penetrate the placental barrier and does not have a teratogenic effect on the formation, development and growth of the fetus.

When used topically, erythromycin does not accumulate in breast milk.

Overdose

Cases of overdose with erythromycin have not been recorded to date (subject to local use).

Side effects

After application to the skin may appear skin reactions, which are characterized by itching, redness of the treated areas, peeling and dryness. When using eye ointment, increased lacrimation, redness of the eye sclera and burning sensation are possible.

These phenomena should subside within 15-30 minutes after using the ointment. If signs of an allergy persist for more than 48 hours, you should consult a doctor.

Important ! At long-term use erythromycin ointment may reduce the effectiveness of treatment resulting from the resistance of microorganisms to active substance. Against this background, the addition of a secondary infection cannot be ruled out.

Composition and release form

The main component of the ointment is erythromycin, which has high efficiency in therapy bacterial infections. Medical vaseline, anhydrous lanolin and synthetic sodium derivatives are used as auxiliary ingredients. The drug is packaged in aluminum tubes of 3 g, 7 g, 10 g and 15 g.

Pharmacokinetics

The drug is not absorbed and does not penetrate into the bloodstream, as a result of which there is no connection with plasma proteins.

Storage

Maximum permissible temperature storage of erythromycin ointment – ​​15 degrees. Shelf life is 2 years from the date indicated on the original packaging.

Erythromycin eye ointment is an ophthalmic drug based on the non-toxic antibiotic erythromycin from the macrolide group. It is active against most gram-positive bacteria.

The ointment is used to eliminate eye diseases that are caused by microorganisms sensitive to it (mycoplasma, ureaplasma, chlamydia, etc.).

Release form and composition

The drug is available in the form of an eye ointment, packaged in aluminum tubes of 15, 10, 7, 3 grams. His active substance is erythromycin (10,000 units).

TO auxiliary components include sodium disulfide (0.0001 grams), anhydrous lanolin (0.4 grams), special petroleum jelly (up to 1 gram). Instructions for use are supplied with each package.

pharmachologic effect

Erythromycin is an antibacterial substance; it belongs to the group of macrolides. Eye ointment has a pronounced bacteriostatic effect on significant amount gram-negative and gram-positive microorganisms (streptococci, staphylococci, gonorrheal bacilli, etc.), including strains resistant to other antibacterial strains.

The drug is also active against actinomycetes, mycoplasmas, clostridia, corynebacteria, listeria, Haemophilus influenzae, and chlamydia.

Viruses, most gram-negative bacteria, fungi, and mycoplasmas show resistance to this drug.

The tolerability of erythromycin is much better than that of penicillins, so it can be used if you are allergic to the latter. Resistance to this component of the microflora develops quite quickly.

Indications for use

Erythromycin ophthalmic ointment is used to treat:

• bacterial blepharitis;
• conjunctivitis (including those occurring in newborns);
• trachoma, chlamydia;
• ophthalmia of newborns.

Dosage and method of administration

The ointment must be applied to the lower eyelid three times a day, when treating trachoma up to five times a day. Duration of treatment determined by the form and severity of the disease, but it should not be more than two weeks.

Treatment of trachoma with this drug must be combined with the opening of purulent follicles. When the main clinical manifestations diseases, the drug is used three times a day. The course of therapy for trachoma should not exceed three months.

Contraindications

Contraindications to the use of erythromycin ointment include the presence of hypersensitivity to its components and severe impairment of liver function.

Side effects

Sometimes the drug can cause allergic reactions and local irritation. With prolonged use, in rare cases, a secondary infection may occur, which is caused by microorganisms resistant to the action of erythromycin.

Overdose

To date, no evidence of overdose has been received medicine.

Interaction with drugs of other pharmacological groups

Erythromycin is an antagonist of clindamycin, lincomycin, chloramphenicol. It is capable of significantly reducing the bactericidal effect of all beta-lactams. antibacterial drugs(cephalosporins, penicillins, carbopenems).

Simultaneous use dosage forms external erythromycin, as well as abrasive substances that can cause skin irritation, or with agents that cause exfoliation, leads to a cumulative drying or irritating effect.

Precautions and special instructions

There is not enough experience regarding the use of erythromycin ophthalmic ointment during lactation, pregnancy, and in infants. Therefore, therapy with this drug is possible only in cases where the expected effects significantly exceed the risks of adverse reactions.

To prevent ophthalmia in newborns, it is not recommended to wash eye ointment out of the eye. In children whose mothers have severe gonorrhea, the drug is recommended to be taken simultaneously with aqueous solution penicillin G for parenteral administration.

The ointment should be stored in a cool, dark place and out of reach of aunts. Its shelf life is three years. Price in pharmacy chains Russia is in the range from 20 to 30 rubles per 10 gram tube.