Analogues, indications for use and side effects. The drug 'Cerebrolysin'

In this article, you can read the instructions for use medicinal product Cerebrolysin. Reviews of site visitors - consumers are presented this medicine, as well as the opinions of medical specialists on the use of Cerebrolysin in their practice. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Cerebrolysin analogues, if available structural analogues. Use to treat stroke and brain damage in adults, children, and pregnancy and lactation.

Cerebrolysin- nootropic drug.

Cerebrolysin contains low molecular weight biologically active neuropeptides that penetrate the blood-brain barrier and directly enter the nerve cells. The drug has an organ-specific multimodal effect on the brain, i. provides metabolic regulation, neuroprotection, functional neuromodulation and neurotrophic activity.

Metabolic regulation: Cerebrolysin increases the efficiency of aerobic energy metabolism in the brain, improves intracellular protein synthesis in the developing and aging brain.

Neuroprotective action: the drug protects neurons from the damaging effects of lactic acidosis, prevents the formation free radicals, increases survival and prevents the death of neurons under conditions of hypoxia and ischemia, reduces the damaging neurotoxic effect of excitatory amino acids (glutamate).

Neurotrophic activity: Cerebrolysin is the only nootropic peptidergic drug with proven neurotrophic activity, similar to action natural neuronal growth factors (NGF), but manifested in conditions of peripheral administration.

Functional neuromodulation: the drug has a positive effect on cognitive impairment, improves concentration, memory processes.

Pharmacokinetics

The complex composition of Cerebrolysin, the active fraction of which consists of a balanced and stable mixture of biologically active oligopeptides with a total polyfunctional effect, does not allow for the usual pharmacokinetic analysis of individual components.

Indications

• Alzheimer's disease;
• dementia syndrome of various origins;
• chronic cerebrovascular insufficiency;
• ischemic stroke;
• traumatic injuries to the head and spinal cord;
• delay mental development in children;
• hyperactivity and attention deficit in children;
• endogenous depression resistant to antidepressants complex therapy).

Release form

Solution for injections 1 ml, 5 ml, 10 ml and 30 ml (injections in ampoules).

Instructions for use and dosage

The drug should be used parenterally (intravenously or intramuscularly). The dose and duration of use depend on the nature and severity of the disease, as well as the age of the patient. Perhaps a single administration of the drug at a dose of up to 50 ml, but it is more preferable to conduct a course of treatment.

• Acute conditions (ischemic stroke, traumatic brain injury, complications of neurosurgical operations) - from 10 ml to 50 ml.
• In the residual period of cerebral stroke and traumatic injury to the brain and spinal cord - from 5 ml to 50 ml.
• Psychoorganic syndrome and depression - from 5 ml to 30 ml.
• Alzheimer's disease, dementia of vascular and combined Alzheimer's-vascular genesis - from 5 ml to 30 ml.
• In neuropediatric practice (in children) - 0.1-0.2 ml / kg of body weight.

To increase the effectiveness of treatment, repeated courses can be carried out as long as there is an improvement in the patient's condition due to treatment. After the first course, the frequency of injections can be reduced to 2 or 3 times a week.

Cerebrolysin is administered parenterally as intramuscular injections(up to 5 ml) and intravenous injections (up to 10 ml). The drug in a dose of 10 ml to 50 ml is recommended to be administered only by slow IV infusion after dilution with standard solutions for infusion. The duration of infusions is from 15 to 60 minutes.

After opening the ampoule/vial, the Cerebrolysin solution should be used immediately.

Side effect

• sensation of heat;
• sweating;
• loss of appetite;
• dyspepsia;
• diarrhea;
• constipation;
• nausea and vomiting;
• arousal, manifested by aggressive behavior, confusion, insomnia;
• grand mal seizures;
• convulsions;
• reactions hypersensitivity, manifested by headache, pain in the neck, limbs, lower back, shortness of breath, chills and a collaptoid state;
• skin hyperemia;
• itching and burning at the injection site;
• arterial hypertension;
• arterial hypotension;
• fatigue;
• tremor;
• depression;
• apathy;
• dizziness;
• flu-like symptoms (cough, runny nose, respiratory infections).

Contraindications

• acute renal failure;
• epileptic status;
• hypersensitivity to the drug.

Use during pregnancy and lactation

Cerebrolysin should be used with caution in the 1st trimester of pregnancy and during lactation.

The use of the drug during pregnancy and during breastfeeding possible only if the intended benefit to the mother outweighs potential risk for the fetus/newborn.

results experimental studies do not give reason to believe that Cerebrolysin has any teratogenic effect or has a toxic effect on the fetus. However, similar clinical researches were not carried out.

special instructions

With excessively rapid injection, a feeling of heat, sweating, dizziness may occur. Therefore, the drug should be administered slowly.

Compatibility of the drug (within 24 hours at room temperature and lighting) has been tested and confirmed with the following standard infusion solutions: 0.9% sodium chloride solution, Ringer's solution, 5% dextrose (glucose) solution.

Simultaneous use of Cerebrolysin with vitamins and drugs that improve cardiac circulation however, these drugs should not be mixed in the same syringe with Cerebrolysin.

Cerebrolysin and Balanced Amino Acid Solutions should not be mixed in the same infusion solution.

Only Cerebrolysin Clear Solution should be used and only once.

Influence on the ability to drive vehicles and control mechanisms

Clinical trials have shown that Cerebrolysin does not affect the ability to drive vehicles and use of mechanisms.

drug interaction

With the simultaneous use of Cerebrolysin with antidepressants or MAO inhibitors, mutual enhancement of their action is possible. In such cases, it is recommended to reduce the dose of the antidepressant.

Cerebrolysin is incompatible with solutions containing lipids and with solutions that change the pH of the medium (5.0-8.0).

Analogues of the drug Cerebrolysin

Cerebrolysin has no structural analogues for the active substance.

Analogues for pharmacological group(nootropic drugs):

• Actovegin;
• Amilonosar;
• Aminalon;
• Ampasse;
• Bilobil;
• Gammalon;
• Gleacer;
• Gliatilin;
• Glycine;
• Glutamic acid;
• Gopantam;
• Hopantenic acid;
• Delecite;
• Demanol;
• Idebenone;
• Intellan;
• Cortexin;
• Lucetam;
• Mexiprim;
• Mexifin;
• Memotropil;
• Minisem;
• Neuromet;
• Nootropil;
• Noocholine Rompharm;
• Noocetam;
• Pantogam;
• Picamilon;
• Pirabene;
• Piracetam;
• Pyriditol;
• Pramistar;
• Semax;
• Tenoten;
• Phenibut;
• Phenotropil;
• Ceraxon;
• Cerebramin;
• Cerebril;
• Cerebrolysate;
• Encephabol;
• Escotropil.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.

Reading time: 11 minutes

Cerebrolysin is prescribed for pathological conditions characterized by a decrease in the functional activity of various brain structures and a deterioration in the nutrition of neurocytes. The drug improves the nutrition of the brain.

Cerebrolysin is a solution for injection, which is a clear yellowish-brown liquid.

The composition of the drug

The drug is sold in tinted glass ampoules of 1, 2, 5, 10 and 20 ml. Ampoules are packaged in contour cells of 5 pieces and packed in a cardboard box.
Cerebrolysin is also available for intravenous injection in 30 ml glass vials. This form the drug is packaged in cardboard packs of 1 or 5 pieces.

Pharmacological effects

Cerebrolysin belongs to the group of nootropic drugs. Therapeutic action is determined by the content of a complex of low molecular weight peptides, which are otherwise called neurotransmitters. Therefore, when using it, you can achieve the following therapeutic effects:

• increases the effectiveness of aerobic metabolism (the chemical process in which energy is produced);
• improves nutrition of the brain;
• the drug increases the resistance of brain structures to various damaging processes (hypoxia, intoxication) and has antioxidant effect;
• regulates the growth of cells of the nervous system, in other words, the action of the drug is aimed at slowing down / stopping the progression of hereditary and acquired pathologies of the nervous system;
• Cerebrolysin has a stimulating effect on the functioning of the brain, improves memory, mental thinking, and generally increases efficiency.

Indications

Cerebrolysin is prescribed for pathological conditions characterized by a decrease in the functional activity of various brain structures and a deterioration in the nutrition of neurocytes. The following indications for prescribing the drug are also distinguished:

• ischemic stroke;
• dementia (deterioration of mental activity) of various etiologies;
• cerebrovascular pathology that provokes cerebral atherosclerosis;
• lag in intellectual / speech development in childhood;
• disorders formed against the background of lack of attention in children;
• trauma to the brain/spinal cord;
• endogenous depression, not amenable to the effects of antidepressants (prescribed by a psychotherapist);
• neurological consequences hemorrhagic stroke.

Contraindications

Absolute contraindications to the appointment of the drug are:

• intolerance to any of the constituent components;
• severe forms kidney failure;
• epileptic status.

With caution, Cerebrolysin is prescribed in the presence of allergic diathesis and epileptic diseases (taking a nootropic can cause an increase in the frequency and severity epileptic seizures), hyperactivity in children (the drug has a stimulating effect).

Cerebrolysin: instructions for use (dosage and method of administration)

The drug is intended for parenteral administration. The dosage and course of treatment is selected individually in each case, depending on the age of the patient and the severity of the pathology. In some conditions, a one-time administration of a nootropic, in a volume of 50 ml, is indicated, but the reproduction of a course of treatment is considered a more preferable option.

The drug is administered intramuscularly if the dose of the drug does not exceed 5 ml. Injections from 10 to 50 ml. diluted with standard solutions for infusion and slowly injected through an intravenous dropper.
Permissible dosage of Cerebrolysin for different states listed in the table:

Doctor's advice

From the practice of application, I can say that Cerebrolysin is a really excellent drug. I often prescribe to patients in the acute period of a stroke, as well as at the recovery stage, it helps many to regain lost functions. However, the earlier therapy is started, the more effective Cerebrolysin is, but this rule applies to all drugs prescribed for stroke. Direct analogues in tablets this tool no, but there are medicines with similar action and well proven. These are Ceraxon in tablets and sachets (cost from 600 and from 1300 rubles, respectively), Cytoflavin (average cost from 400 rubles), Actovegin (cost from 1400 rubles), Semax nasal drops (average cost from 350 rubles).

Side effects

Side effects of the drug include:

• allergic reactions (skin rash, bronchospasm, anaphylactic shock, etc.);
• disorders mental nature(increased excitability, aggression, insomnia, confusion);
• cramps of the limbs;
• increase in blood pressure;
• arrhythmia, increased heart rate (develops due to improper injection);
• nausea, vomiting;
• defecation disorders;
• loss of appetite;
• headache.

In rare cases, a slight seal appears at the injection site. In the presence of side effects consult a neurologist

Side effects "Cerebrolysin" rarely gives. Most often it is a headache or hyperexcitability in both children and age patients. The problem is solved by reducing the dose of the drug by half or canceling it. Cerebrolysin is included in the Vital and Essential Drugs List, which means that when appointed by a regional specialist, if the budget allows, it can be prescribed and dispensed in a pharmacy for free. However, given the cost of the drug, this is rare.

Features of use

Before using the drug, you should carefully study the instructions for use, as well as take into account certain nuances when using it:

• it is necessary to open the ampoule immediately before the injection; it is forbidden to store an open container with a solution;
• for intravenous infusions, it is allowed to use Ringer's solution, sodium chloride and glucose 5% as a solvent;
• the prepared preparation is administered immediately;
• the drug can be combined with injections of vitamins and drugs that improve cerebral circulation, but in different syringes;
• the drug is incompatible with a solution of amino acids;
• the presence of impurities, sediment, foreign elements in the solution is not allowed;
• when using Cerebrolysin as a complex therapy, a single dose of the drug is reduced;
• nootropic treatment in pregnant and lactating women is carried out exclusively for honey. indications under strict medical supervision;
• the use of the drug is possible only on prescription.

Overdose

Cases of overdose with the use of the drug Cerebrolysin were not observed.

Cerebrolysin analogues in tablets

Pharmacies offer a large selection of drugs that are similar in action and indications for use with Cerebrolysin. Generic (analogous to the active substance) is Cerebrolysate, but it must be understood that it is impossible to arbitrarily replace the prescribed drug with another drug.

Shelf life and shelf life

The drug is stored in a cool (temperature limit should not exceed 25 degrees), dark place.

Shelf life of bottles - 2 years, ampoules - 5 years from the date of manufacture.

The price of the drug Cerebrolysin

The average cost of Cerebrolysin per package ranges from 630 to 1550 rubles.

FAQ:

What is more painful to put Cerebrolysin or Cerebrolysate

Based on patient feedback, it can be said with confidence that Cerebrolysin injections are much easier for patients to tolerate. If the drug is administered strictly according to the rules, then pain practically do not occur.

How long does it take to get better after taking medication

Improvements usually appear after 3-5 injections, but the effectiveness of the drugs depends on the severity and degree of neglect of the pathology.

Cerebrolysin and protein allergy

If the patient is allergic to proteins of animal origin, then the use of Cerebrolysin is prohibited, especially in the treatment of children. During therapy, allergic reactions may develop in the form of bronchospasm, severe shortness of breath, rash, etc. It is almost impossible to stop these symptoms with antihistamines.

On the compilation of combinations of applied nootropics, see the video:

Useful articles

Cerebrolysin - prescription drug in ampoules for intravenous and intramuscular injection obtained from the brain of a pig.

The drug has a nootropic effect and is used for violations of cognitive functions, to restore the body after a stroke, head injury and other organic brain lesions.

The issue of selecting Cerebrolysin analogues is relevant for those who are not suitable for the injectable form, if the patient cannot afford an expensive drug or there are other reasons. Coordinate the choice of substitutes with your doctor, many of them are not sold freely in pharmacies.

The drug is synthesized from the brain of a pig and has many beneficial effects:

• enhances the restoration of damaged parts of the nervous system and has an anti-inflammatory effect;
• prevents the death of neurons in damaged tissue;
• contributes to the improvement of cognitive functions, concentration of attention and memorization processes;
• improves the processes of energy metabolism of the brain.

The drug is of particular benefit to patients with Alzheimer's disease when it is a disease-modifying agent. Cerebrolysin reduces the frequency and severity of clinical relapses of the disease, reduces accumulated damage within the brain, slows down the growth of disability for a long time.

Indications for use of Cerebrolysin

The medication is prescribed by a doctor for the treatment of children and adults with the following diseases:

1. damage to the brain and spinal cord due to trauma;
2. Alzheimer's disease;
3. dementia of various nature;
4. recovery after ischemic stroke;
5. chronic cerebrovascular insufficiency;
6. in childhood - mental retardation, attention deficit, hyperactivity.

In the presence of status epilepticus and acute renal failure, the medication is replaced by approved analogues.

Cerebrolysin - instructions for use

The drug is sold by prescription and used as prescribed by a doctor. Method of use - intravenously, as part of droppers with glucose, saline or Ringer's solution, intramuscularly. The route of administration is affected by the severity of the disease and the age of the patient, the prescribed amount of ml. So, up to 5 ml is injected intramuscularly, from 5 to 10 - intravenously, over 10 ml - added to droppers.

The course of treatment is 10-20 days, the medicine is administered every day. In severe organic lesions of the brain, an increase in the course is possible, according to the scheme in 2-3 days.

Cerebrolysin when to inject - in the morning or in the evening

Cerebrolysin refers to nootropic drugs that are best injected in the morning. With evening administration, an undesirable reaction is possible - insomnia or insomnia.

The patient's well-being during and after the injection is affected by the speed of manipulation. Well tolerated if the drug is administered slowly. With rapid infusions, a person complains of fever, dizziness, sweating, confusion.

Cerebrolysin analogs

The price of Cerebrolysin depends on the number of ml in an ampoule and varies from 1 thousand to 3.5 thousand for 5-10 pieces. Usually, one package is not enough for a course, so treatment becomes inaccessible for some categories of patients, in particular, pensioners. How to replace Cerebrolysin depends on the indications and complaints of the patient, the presence of contraindications, financial possibilities, preferences for the form of the drug (ampoules or tablets).

Modern analogues of Cerebrolysin with prices and country of origin

The Cerepro analogue consists of choline alfoscerate in the form of ampoules and capsules. It is used for dementia, ischemic stroke, TBI, cerebrovascular insufficiency, as a nootropic. It is prescribed by a doctor and dispensed by prescription.

Cerepro analogues with a similar composition:

• Alfocholine (Belarus);
• Gleatser (Russia);
• Gliatilin (Italy);
• Nooprin (Russia);
• Cereton (Russia), etc.

Domestic analogue Cytoflavin improves brain metabolism. The medicine consists of succinic acid, riboxin, nicotinamide, riboflavin. It is produced in ampoules and tablets, it is dispensed by prescription for cerebrovascular diseases, cerebral infarction, neurasthenia.

Magnesium

The multivitamin complex Magnesium compensates for the deficiency of magnesium citrate and ascorbate. Used after injury nervous disorders for the rehabilitation of persons with cardiovascular diseases.

Cerebrolysin or Cortexin - which is better for an adult and a child

Cortexin is an analogue cheaper than Cerebrolysin in ampoules, also obtained from the brain of pigs. Available in powder, before use it is dissolved in sodium chloride, water or novocaine. The drug is administered intramuscularly once a day, with severe lesions - twice a day. It is a painful prick.

Cerebrolysin substitute has similar effects. The drug improves cognitive functions, improves metabolism in damaged brain tissues and protects cells from destruction and adverse factors, accelerates peptide synthesis and metabolic processes. Restrictions for use are pregnancy and individual intolerance to the components.

Cerebrolysin is a similar drug in the form of ampoules ready for administration. It has the same therapeutic effects as Cortexin. It has positive reviews doctors.

What is the difference between the two analogues:

• The cost of Cortexin is lower.
• Cerebrolysin is not used in status epilepticus and acute renal failure, in which case Cortexin is the drug of choice.
• Child and adult low degree Cortexin is recommended for brain damage; in severe conditions, Cerebrolysin is more often prescribed.

Which is better - Cortexin or Cerebrolysin, depends on the severity of the patient's condition, indications, history of contraindications, financial capabilities.

Cerebrolysin or Actovegin - which is better for blood vessels for an adult

Actovegin is an analogue of Cerebrolysin injections, also available in tablets for maintenance therapy. It is based on hemoderivate of calf blood. Among the therapeutic effects are the activation of metabolism in tissues, the improvement of trophic processes and the stimulation of regeneration.

To figure out which is better - Actovegin or Cerebrolysin, is it possible to take these drugs at the same time, you need to compare them:

• both drugs have a nootropic effect;
• with ischemic stroke, dementia, neurological pathologies, it is possible to use any medication;
• Cerebrolysin is better for improving cognitive functions - memory, attention, learning;
• Actovegin is more often prescribed for violation of peripheral circulation and diabetic polyneuropathy;
• sharing is possible, and two drugs cannot be taken into one syringe.

What is better in a particular case is determined by the doctor.

Cerebrolysin or Ceraxon

Ceraxon is a nootropic agent based on citicoline, prescribed for ischemic, hemorrhagic stroke, TBI and cognitive impairment. Often used for the elderly.

One of the differences between the analogue of the drug Cerebrolysin is an additional form in the form of a solution for oral administration. It is packaged in a bottle with a dosing syringe or disposable sachets.

Ampoules of Ceraxon are administered intramuscularly or intravenously, depending on the indications and the severity of the patient's condition. Then it is possible to enhance the effect with an oral solution.

The analogue restores damaged brain cells, improves cognitive functions, prevents the death of ischemic tissues, and reduces the severity of neurological manifestations of diseases.

Ceraxon is different from Cerebrolysin at a lower cost and the presence of an additional form of release - a solution for oral administration. Both drugs are used to recover from TBI and stroke, with impaired cognitive function. However, Cerebrolysin is also used in children with developmental delay, hyperactivity and attention deficit disorder, in Alzheimer's disease. The mechanisms of action of drugs are different due to the incoming substances - Cerebrolysin consists of polypeptides, cheap analogue Ceraxon contains citicoline.

Citicoline is also found in Proneiro, Recognan, Neipilept and others. Which is better is determined by the doctor specifically for each patient.

Cerebrolysin or Mexidol - which is better

Cerebrolysin analogue in ampoules 5 ml - antioxidant domestic drug Mexidol. It differs in the spectrum of action and indications.

Mexidol analogue has antioxidant, antihypoxic, nootropic, anticonvulsant action. With a course of treatment, it improves blood supply to the brain and metabolism in tissues, reduces anxiety. Used for acute form cerebrovascular accidents, encephalopathy, TBI, mild cognitive and anxiety disorders. Available in ampoules, tablets to enhance the therapeutic effect. The tablet form is suitable for those patients who do not have the opportunity to use injections.

Which is better - Mexidol or Cerebrolysin, depends on the indications.

Cerebrolysin or Piracetam

Piracetam is an analogue of Cerebrolysin in tablets, capsules and injections. The drug is weaker, since it has a nootropic effect, improves metabolism in brain cells, and affects the properties of blood cells.

The main indications for the use of the analog are the treatment of cognitive impairment after a stroke or other organic brain lesions, the therapy of decreased attention, dizziness, and tinnitus. Not used for hemorrhagic stroke.

Piracetam is marketed by manufacturers under the following trade names:

• Lucetam;
• Nootropil.

Also included in complex preparations with cinnarizine - Phezam, Nookam, Omaron.

What to choose from analogues, consult your doctor.

Cerebrolysin or Cerebrolysate

The two drugs have a similar mechanism of action and healing effects are available in ampoules. Cerebrolysate (Cellex substitute) is more effective in cerebral palsy, nerve root diseases, after surgical intervention on the brain. The route of administration is exclusively intramuscular.

Cerebrolysin is a studied Austrian drug for developmental delays in children and dementia, after a stroke. This means that as a result clinical trials indications, contraindications, side effects, dosing regimen were determined. The drug is used intramuscularly, intravenously and as part of droppers. The only drawback is the high cost.

When choosing between analogues, one should take into account financial possibilities, efficiency and sufficient research.

Discuss the choice of analogues cheaper than Cerebrolysin with your doctor due to possible contraindications, side effects and nuances of appointment. Many medicines with similar actions are not sold freely in pharmacies. Before use, read the instructions for use.

Answers on questions

1. Cerebrolysin - prescription or not?
   

   Yes, the drug is prescription and is used as prescribed by a doctor. Dosage, course of treatment are also determined by a specialist.

2. How is Cerebrolysin administered - intravenously or intramuscularly?
   

   The method of administration is determined by the doctor based on the patient's condition, severity of the disease, age. The medicine up to 5 ml is administered intramuscularly, up to 10 ml intravenously, over 10 ml is prescribed in the form of droppers with other permitted solutions.

3. Cerebrolysin raises or lowers blood pressure?
   

   Among the side effects when using the drug and exceeding the dosage are arrhythmia, heart palpitations, an increase or decrease in blood pressure.

For the prevention of recurrent heart attack and for the treatment mental disorders shows Cerebrolysin.

The drug belongs to the group of nootropic substances, enriches brain cells with oxygen, has a slight calming effect.

The active substance is peptides obtained from the pig brain, which have the same name with the drug.

In the list of indications for heart disease - vascular system, Alzheimer's disease, children's mental problems, heart attack and stroke.

Release form - solution in ampoules and vials. Application is possible even in preventive purposes. The price depends on the number of ampoules in the package, ranging from 700 to 1400 rubles.

Read what are the cheap analogues of Cerebrolysin of domestic and foreign production.

Domestic generics are inexpensive synonyms that also have a beneficial effect on brain function.

Russian-made tablets differ from each other in the list of indications.

Among the best drugs from the group of nootropics:

• Amilonosar. Release form - solution and tablets. The drug helps prevent a second heart attack or stroke.

  The tablets act directly on the central nervous system, which helps to get rid of migraines and insomnia. The price for a package is 140 rubles.

• Cortexin. A powerful drug designed for a long course of treatment.

  Injections help restore blood circulation in the brain, have a slight sedative effect. Also on the list of indications are epileptic seizures.

  The drug is contraindicated in children, pregnant and lactating women. The average cost is 1100 rubles.

• Vinpocetine. The drug also belongs to the group of nootropics, but with the same name active substance contains vinpocetine.

  Possesses similar action, on sale can be found in the form of an injection solution and tablet form. The price for a package is 170 rubles.

• Picamilon. Domestic generic having wide range actions.

  The drug can be used to restore normal mental health, during the period of treatment for alcoholism, depression, even helps with headaches. Price - 100 rubles per pack.

Among the drugs of a domestic manufacturer, you can choose an inexpensive option. The cheapest synonym is Picamilon, which you can buy for 100 rubles.

Expensive but potent drug sold in injections - Cortexin, costs more than 1100 rubles.

Ukrainian generics

Foreign manufacturers also produce budget medicines. Among the synonyms of Ukrainian production, you can find tablets for 50 rubles.

These drugs belong to the group of nootropics and psychostimulant drugs:

• Thiocetam. A drug that is prescribed during the rehabilitation period after traumatic brain injury.

  Also, taking the drug is indicated for the prevention of recurrent heart attack and stroke.

  Lack of medication in big list contraindications. The price for packing is 500 rubles.

• Ginkgo biloba. The drug for plant-based, which is prescribed to increase performance and improve brain activity.

  Ginkgo biloba extract has the ability to strengthen blood vessels. Price - 80 rubles.

• Piracetam. Ukrainian generic, which can even be used to treat children. Age limit - contraindicated in the first year of life.

  Release form - tablets, capsules and solution. The tablet form will be cheaper - only 50 rubles per pack.

The list of nootropics can go on and on.

Each medication has its own advantages and disadvantages. Piracetam is the cheapest synonym, costing only 50 rubles.

However, Ginkgo biloba tablets are a plant-based drug that has a minimum of side effects.

Other foreign substitutes

To improve brain activity, you can look at imported generics. Foreign-made drugs have a similar effect.

Acquainted with short instruction according to the application can be in the table:

Name of imported medicine	Description and indications for use	Average price in a pharmacy
Nootropil	Polish medicine widely used in narcology, psychiatry and neurology. Release form - solution, injections, capsules and tablets. It has a fairly impressive list of side effects, overdose symptoms were observed during the study	280 rubles
Aminalon	It is indicated during the rehabilitation period after a stroke, traumatic brain injury. And for the treatment of migraines, dizziness. The list of contraindications includes children, pregnant and lactating women, as well as patients with individual intolerance to the components	150 rubles
Ceraxon	A close substitute that has an identical mode of action. Instructions for use of the drug does not differ from the list of indications and contraindications of the original. However, you cannot call it a cheap synonym, its cost exceeds the price of Cerebrolysin	1200 rubles
Piracetam Vial	A Chinese drug that can improve memory, increase intellectual abilities and enrich brain cells with oxygen. Mostly prescribed in old age. It is also used to treat drug addicts and alcoholics from long-term dependence.	70 rubles

The best option in terms of finances is Piracetam Vial. Generic belongs to the group of nootropics, it costs only 70 rubles.

The structural substitute in composition is Ceraxon, the cost of which even exceeds the original. Read before starting treatment complete instructions on the use of analogue.

Attention! replacement original drug for a cheap generic, you must agree with your doctor.

You should not make such decisions on your own, each synonym has its own contraindications.

Cerebrolysin analogues are cheaper

1 (20%) 1 vote

Cerebrolysin refers to nootropic drugs, which include low molecular weight peptides, which are obtained from the brain tissue of pigs. Despite the fact that the clinical efficacy of the drug has not yet been proven, cerebrolysin and its analogues are actively prescribed by neurologists and psychiatrists.

Testimonies of patients in most cases indicate an improvement in the clinical picture of the course of the disease after treatment with cerebrolysin, and also note the drug with a positive effect on the brain. It is worth knowing that the drug Cerebrolysin has a certain list of contraindications, which does not recommend its use in the treatment of some patients.

In such situations, patients are prescribed cerebrolysin analogues. In addition, the doctor may prescribe an analogue if the patient asks to prescribe him more cheap drug, because, unfortunately, cheap raw materials did not lead to a low cost of the final drug (the cost of Cerebrolysin starts from 650 rubles).

Cerebrolysate

Cheap analogues of cerebrolysin are not easy to find, but cerebrolysate is one of them. The main difference between cerebrolysate and cerebrolysin is that cerebrolysate is derived from bovine brain cells, not pigs. An analogue is produced in the same forms as Cerebrolysin - in ampoules, in the form of a liquid solution for injections.

Cerebrolysate as an analogue of cerebrolysin is used to treat the following diseases:

• radiculopathy caused by various sources;
• neropathy and myelopathy;
• brain injury;
• as part of complex therapy in the post-stroke state;
• disturbances in the work of the central nervous system caused by starvation of the brain due to its poor blood supply;
• low level of concentration.

List of contraindications

There are a number of situations in which Cerebrolysate should not be used.

1. High sensitivity to the composition of the drug.
2. Pregnancy up to 12 weeks
3. Epilepsy
4. Problems in the work of the kidneys.

With extreme caution, cerebrolysate is prescribed in such cases as:

• baby feeding breast milk;
• second and third trimesters of pregnancy;
• acute renal failure;
• diathesis of allergic etiology.

Cerebrolysate can be attributed to cheap analogues of Cerebrolysin, its price is lower than that of the original, and starts from 180 rubles per pack. The entry of this drug into the niche of cheap analogues of Cerebrolysin makes it an extremely popular drug.

Actovegin

Actovegin is another analogue of cerebrolysin, which is produced from calf red blood cells. The basis for production is its main difference directly from celebrolysin.

There are several types of actovegin release forms:

• ointment;
• cream;
• gel;
• solution for infusion;
• injection.

It is worth considering that of all the existing forms, only solutions for intravenous and intramuscular administration and tablets belong to the analogues of cerebrolysin. Other varieties of forms of the drug are designed to heal damage skin and relieve joint pain.

Indications for prescribing the drug

Indications for prescribing the drug directly depend on its dosage form, solutions for injections and infusions.

Application

The appointment of a solution for intravenous infusion, as well as for intramuscular injections as an analogue of cerebrolysin, is indicated for such diagnoses as:

• ischemic stroke;
• traumatic brain injury;
• arterial vascular disorders
• trophic ulcers;
• angiopathy;
• diabetic polyneuropathy;
• the presence of wounds;
• restoration of the skin and mucous membranes after radiation therapy.

Pills

Doctors prescribe Actovegin in tablets to patients to improve their condition during the course of such diseases and conditions as:

• vascular disorders of the brain;
• metabolic disorders of the brain;
• insufficient supply of blood to the brain;
• traumatic brain injury;
• dementia;
• venous vascular disorders;
• arterial vascular disorders;
• trophic ulcers;
• angiopathy;
• diabetic polyneuropathy.

List of contraindications

The list of contraindications to the use of Actovegin is directly related to the form of the prescribed drug.

For infusion solutions and solutions for intramuscular injection

A number of strict contraindications that prohibit the appointment of the drug include:

• slow excretion of fluid by the body;
• decompensated heart failure;
• oliguria;
• anuria;
• swelling of the respiratory system;
• allergy to the composition of the drug.

The appointment of actovegin with extreme caution should be with:

• hypernatremia;
• hyperchloremia;
• pregnancy and breastfeeding (in such a situation, the benefit to the body of the expectant mother should be much higher than all the risks that the fetus will be exposed to during therapy)

For tablets

Actovegin tablets are absolutely contraindicated only if their components are intolerant to the patient's body. In other cases, the use of the drug is permissible. It is worth considering that under certain conditions Actovegin tablets should be taken with extreme caution. These states include:

• heart failure of the second and third degree;
• hyperhydration;
• swelling of the respiratory system;
• anuria;
• oliguria;
• pregnancy;
• feeding the baby with breast milk.

At the risk of getting expressed allergic reaction, in no case should you prescribe actovegin yourself as an analogue of cerebrolysin, especially since this analogue is not included in the category of cheap drugs. The cost of the drug in the form of solutions is almost equal to the cost of Cerebrolysin, and the cost of tablets goes far beyond the budget (or cheap) segment. medicines, reaching a figure of 1600 rubles and more.

Cortexin

Cortexin is one of the drugs belonging to the order of nootropics. Cortexin is obtained from cells located in the cerebral cortex of cattle and pigs. The difference between Cortexin and other analogues of Cerebrolysin is a larger range of indications for prescribing at the same time with a smaller list of contraindications and with extremely rare side effects. The good tolerability of the analogue was the reason that the greatest use of Cortexin is in child psychiatry and neurology. Children under 3 years of age are prescribed it free of charge, while older patients have to purchase Cortexin on their own. Unfortunately, the popularity of the drug did not put Cortexin on the list of cheap drugs.

Indications for prescribing the drug

Cortexin as an analogue of cerebrolysin is prescribed to patients in the following situations:

• disturbances in the blood supply to the brain;
• viral neuroinfections;
• bacterial nature;
• traumatic brain injury;
• asthenic syndrome;
• encephalopathy with various sources;
• vegetative suprasegmental disorders;
• memory problems;
• thinking problems;
• epilepsy;
• encephalitis;
• encephalomyelitis.

• Reduced susceptibility to learning;
• delay in psychomotor development;
• delay in speech development;
• the presence of perinatal CNS injuries.

List of contraindications

• pregnancy;
• lactation;
• allergic to Cortexin.

It should be noted that Cortexin is not the cheapest drug among analogues; moreover, its cost is often higher than the cost of cerebrolysin itself and starts from 750 rubles.

Mexidol

Unlike Cerebrolysin, Mexidol is not a nootropic, but an antioxidant drug. The action of the analogue is based on the fact that Mexidol protects cells from excessive oxidation, promotes the restoration of intercellular membranes, and increases the tolerance of hypoxia by tissues. The generic is similar directly to cerebrolysin in that both the original composition and the analogue of the drug activate mental activity, improve memory and increase learning.

The indisputable advantage of Mexidol is its price. Mexidol is the cheapest analogue of Cerebrolysin.

Indications for prescribing the drug

Mexidol is prescribed to the patient in the presence of such diagnoses as:

• acute disorders in the blood circulation of the brain;
• vegetovascular dystonia;
• cardiopsychoneurosis;
• encephalopathy;
• atherosclerosis;
• neuroses;
• panic attacks;
• acute poisoning with neuroleptic drugs;
• alcoholism;
• inflammatory processes in the peritoneum in the acute stage;
• tissue hypoxia;
• extreme environmental conditions.

List of contraindications

Despite numerous positive sides mesidol also has a certain list of contraindications that do not allow the use of this drug.

1. Liver failure.
2. Renal failure.
3. Allergy to active active ingredients medicinal product.
4. Pregnancy.
5. Feeding the baby with breast milk.

Mexidol can be confidently included in the segment of cheap medicines. The cost of one package of analogue starts from 40 rubles. The availability of Mexidol (due to the cheap price) provided the drug with exceptional popularity and active use for the treatment of patients in hospitals.

Ceraxon

Ceraxon, like Cerebrolysin, belongs to nootropic drugs designed to fight brain and central nervous system damage. This is an advanced development of Russian scientists. The main difference between the drugs is the base. For the fundamental component of ceraxon, a synthetically created substance, citicoline, was taken.

Indications for prescribing the drug

Ceraxon as an analogue to Cerebrolysin is prescribed when the following diagnoses are detected:

• recovery in the post-stroke period;
• the presence of a traumatic brain injury;
• acute period of ischemic stroke;
• the presence of cognitive disorders, the cause of which is degenerative and vascular diseases brain;
• Availability behavioral disorders, the cause of which is degenerative and vascular diseases of the brain.

List of contraindications

1. Expressed vagotonia.
2. Sensitivity to the components of the drug.
3. Pregnancy.
4. lactation period.

In addition, ceraxon cannot be used as an analogue of cerebrolysin if the patient is under 18 years of age.

It will not work to save money by purchasing ceraxon as an analogue of Cerebrolysin. This drug can not be called cheap. In most pharmacies, the cost of both drugs is approximately the same.

Each of the nootropic substitutes discussed, Cerebrolysin, has its own advantages and disadvantages, including the presence of side effects and cheaper or more expensive cost. Asking the question what is better cerebrolysate or cerebrolysin, cortexin or another analogue of cerebrolysin, the patient should keep in mind that the drug is prescribed by the doctor based on the patient's history and clinical picture the use of the drug, so if the attending physician has prescribed Cerebrolysin, then the patient should obey and take this particular drug, and not its cheaper or more expensive counterparts.