Teturam analogs with the least side effects. Teturam analogues and prices Teturam analogues with fewer side effects
This page contains a list of all Teturam analogues by composition and indications for use. A list of cheap analogues, and you can also compare prices in pharmacies.
- Most cheap analogue Teturam:
- The most popular analogue of Teturam:
- ATH classification: Disulfiram
- Active ingredients / composition: disulfiram
Cheap analogues of Teturam
| # | Name | Price in Russia | Price in Ukraine |
|---|---|---|---|
| 1 | 94 rub | 159 UAH | |
| 2 | disulfiram | 800 rub | 64 UAH |
| 3 | naltrexone hydrochloride Analogue by indication and method of application | 1204 rub | 1150 UAH |
| 4 | cyanamide Analogue by indication and method of application | 1400 rub | 233 UAH |
| 5 | Analogue by indication and method of application | 2790 rub | 31 UAH |
When calculating the cost cheap analogues of Teturam the minimum price was taken into account, which was found in the price lists provided by pharmacies
Popular analogues of Teturam
| # | Name | Price in Russia | Price in Ukraine |
|---|---|---|---|
| 1 | cyanamide Analogue by indication and method of application | 1400 rub | 233 UAH |
| 2 | disulfiram Analogue in composition and indication | 800 rub | 64 UAH |
| 3 | nalmefene Analogue by indication and method of application | 3513 rub | 3922 UAH |
| 4 | L-threonine, pyridoxine hydrochloride Analogue by indication and method of application | 94 rub | 159 UAH |
| 5 | naltrexone Analogue by indication and method of application | 19010 rub | 10168 UAH |
The list of drug analogues based on the statistics of the most requested drugs
All analogues of Teturam
The above list of analogues of drugs, which indicates Teturam substitutes, is the most suitable, since they have the same composition of active ingredients and match the indications for use
Analogues by indication and method of application
| Name | Price in Russia | Price in Ukraine |
|---|---|---|
| metadoxine | -- | 19 UAH |
| -- | 165 UAH | |
| metadoxine | -- | 174 UAH |
| glycine, glucose, sodium formate | -- | 33 UAH |
| naltrexone hydrochloride | 1204 rub | 1150 UAH |
| naltrexone | 19010 rub | 10168 UAH |
| naltrexone | -- | -- |
| naltrexone hydrochloride, triamcinolone acetonide | -- | -- |
| nalmefene | 3513 rub | 3922 UAH |
| L-threonine, pyridoxine hydrochloride | 94 rub | 159 UAH |
| cyanamide | 1400 rub | 233 UAH |
| 2790 rub | 31 UAH |
Different composition, may coincide in indication and method of application
| Name | Price in Russia | Price in Ukraine |
|---|---|---|
| antibodies to the brain-specific protein S-100 affinity purified | -- | -- |
| nicotine | 348 rub | 78 UAH |
| nicotine | 2970 rub | -- |
| nicotine | -- | 126 UAH |
| nicotine | -- | 163 UAH |
| nicotine | -- | 184 UAH |
| nicotine | 1959 rub | -- |
| nicotine | -- | -- |
| varenicline | 988 rub | 995 UAH |
| varenicline | -- | 101 UAH |
| cytisine | 731 rubles | 56 UAH |
| buprenorphine | -- | -- |
| methadone | -- | -- |
| methadone | -- | -- |
| methadone | -- | -- |
| methadone | -- | -- |
| methadone | -- | -- |
| methadone | -- | -- |
| buprenorphine, naloxone | -- | -- |
To compile a list of cheap analogues of expensive drugs, we use the prices provided by more than 10,000 pharmacies throughout Russia. The database of medicines and their analogues is updated daily, so the information provided on our website is always up-to-date as of the current day. If you have not found the analogue you are interested in, please use the search above and select the medicine you are interested in from the list. On the page of each of them you will find everything possible options analogues of the desired medicine, as well as prices and addresses of pharmacies in which it is available.
How to find a cheap analogue of an expensive medicine?
To find inexpensive analogue medicine, generic or synonym, first of all, we recommend paying attention to the composition, namely, to the same active ingredients and indications for use. The same active ingredients of the drug will indicate that the drug is a synonym for the drug, a pharmaceutical equivalent or a pharmaceutical alternative. However, do not forget about the inactive components of similar drugs, which can affect safety and efficacy. Do not forget about the advice of doctors, self-medication can harm your health, so before using any medicinal product always consult your doctor.Teturam price
On the sites below you can find prices for Teturam and find out about the availability of a pharmacy nearbyTeturam instruction
INSTRUCTIONS
on the use of funds
TETURAM
Dosage forms
tablets 250mg
Pharmgroup
Means for the treatment of alcoholism
International non-proprietary name
Disulfiram
Vacation order
Released by prescription
Compound
The active substance is disulfiram.
pharmachologic effect
Anti-alcohol. Inhibits acetaldehyde dehydrogenase and delays the enzymatic biotransformation of alcohol at the stage of acetaldehyde. The accumulation of the latter in the body causes intoxication, which (since consciousness is preserved) is accompanied by severe sensations. Rapidly and completely absorbed in the gastrointestinal tract. It is metabolized quite intensively, recovering to diethyldithiocarbonate, excreted by the kidneys in the form of glucuronide, or decomposes to form diethylamine and carbon disulfide, which is excreted by the lungs.
Indications for use
Chronic alcoholism (relapse prevention, lack of therapeutic effect from other methods), chronic nickel intoxication.
Contraindications
Hypersensitivity, thyrotoxicosis, diabetes, pronounced cardiosclerosis, cerebral atherosclerosis, pre- and post-infarction conditions, aortic aneurysm, coronary insufficiency, hypertonic disease II-III stages, cardiovascular diseases in the stage of decompensation, pulmonary tuberculosis with hemoptysis, bronchial asthma, severe emphysema, erosion of the stomach, diseases of the liver and kidneys, mental illness, epileptiform syndrome, polyneuritis, glaucoma, pregnancy. Restricted use: age over 60 years, peptic ulcer stomach and duodenum(in the acute stage), endarteritis, previously transferred psychosis while taking disulfiram.
Side effect
Metallic taste in the mouth, hepatitis, neuropsychiatric disorders, headache, polyneuritis lower extremities, pruritus, urticaria.
Interaction
Effects, incl. neurotoxic, enhance tricyclic antidepressants (amitriptyline), metronidazole, isoniazid, reduces (reaction to alcohol) - vitamin C. Reduces blood clotting against the background indirect anticoagulants. Increases the toxicity of diphenin.
Overdose
Manifested coma, collapse, various neurological phenomena. Treatment is symptomatic.
Method of application and dosage
inside. The dose is selected individually, is usually 0.25-0.5 g / day. 8-10 tablets are implanted subcutaneously and intramuscularly.
special instructions
No information.
Storage conditions
List B. In a dry place.
Manufacturers
Tatkhimfarmpreparaty (Russia).
In this article, you can read the instructions for use medicinal product Teturam. Reviews of site visitors - consumers are presented this medicine, as well as the opinions of doctors of specialists on the use of Teturam in their practice. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Teturam if available structural analogues. Use for the treatment of chronic alcoholism and elimination of cravings for alcohol in adults, children, as well as during pregnancy and lactation.
Teturam- a drug for the treatment of alcohol addiction. It has an inhibitory effect on the enzyme aldehyde dehydrogenase, which is involved in metabolism ethyl alcohol. This leads to an increase in the concentration of the ethyl alcohol metabolite acetaldehyde, which causes flushing to the face, nausea, vomiting, general malaise, tachycardia, and a decrease in blood pressure, which make it extremely unpleasant to drink alcohol after taking Teturam.
Compound
Disulfiram + excipients.
Pharmacokinetics
After oral administration, there is a rapid, but incomplete (70-90%) absorption of the active substance from the gastrointestinal tract. Due to its high lipid solubility, disulfiram is widely distributed in the body and accumulates in various fat depots. Disulfiram is rapidly metabolized to diethyldithiocarbamate (DDC), which is partially excreted as carbon disulfide in exhaled air and partially metabolized in the liver to methyl-DDC. The latter is converted into an active metabolite - diethylthiocarbamic acid methyl ester (methyl-DTC). With mild or moderate deterioration in liver function, metabolism does not change. On the contrary, with cirrhosis of the liver, an increase in the concentration of metabolites in the blood is observed. Metabolites are excreted mainly in the urine. Part is excreted with exhaled air in the form of carbon disulfide. 20% in the form of unchanged disulfiram is excreted through the intestines. Up to 20% of a dose may remain in the body for 1 week or more. Despite the very low levels, disulfiram-ethanol reactions may occur within 5-9 months after implantation.
Indications
For oral administration:
- prevention of relapse during the treatment of chronic alcoholism.
For implantation:
- treatment of chronic alcoholism
- as a detoxification agent for chronic nickel poisoning.
Release form
Tablets 100 mg, 150 mg, 200 mg and 250 mg.
Other dosage forms, whether it be drops or capsules, does not exist.
Instructions for use and regimen
When taken orally, the dose is 125-500 mg per day, the treatment regimen is determined individually.
When implanted in the subcutaneous fat using a special technique, 800 mg is administered.
Side effect
- metallic taste in the mouth;
- polyneuritis of the lower extremities;
- neuropsychiatric disorders;
- memory loss;
- disorientation;
- headache;
- skin rash;
Reactions due to the association of disulfiram-ethanol: collapse, disorders heart rate, angina attacks, myocardial infarction, cerebral edema.
Contraindications
- severe cardiovascular disease;
- severe liver failure;
- diabetes;
- epilepsy;
- neuropsychiatric diseases;
- concomitant use of phenytoin, isoniazid, metronidazole;
- simultaneous use of drinks containing alcohol or taking medications containing ethanol, as well as their use within 24 hours after taking disulfiram;
- pregnancy;
- lactation;
- hypersensitivity to disulfiram.
Use during pregnancy and lactation
Contraindicated for use during pregnancy and lactation.
Before implantation, pregnancy should be excluded. Against the background of the action of disulfiram, it is necessary to use reliable contraceptives.
Use in children
The drug is contraindicated in children and adolescents under the age of 18 years.
special instructions
Use with caution in patients with kidney failure, diseases of the liver, respiratory system.
drug interaction
With simultaneous use of coumarin derivatives with anticoagulants (including warfarin), the anticoagulant effect increases, and the risk of bleeding increases.
Disulfiram inhibits liver enzymes, therefore, with the simultaneous use of drugs metabolized in the liver, their metabolism may be impaired.
With the simultaneous use of disulfiram with tricyclic antidepressants, phenothiazine derivatives, MAO inhibitors, there is a risk of developing serious adverse reactions associated with drug interactions.
A case of the development of mania in a patient taking Teturam and buspirone is described.
With simultaneous use, the clearance of desipramine and imipramine from the body decreases.
With simultaneous use with amitriptyline, an increase in therapeutic action disulfiram, but it is also possible to increase toxic action amitriptyline on the CNS.
With simultaneous use, the concentration in the blood plasma of diazepam and chlordiazepoxide increases, in some cases accompanied by dizziness. Under the influence of diazepam, a decrease in the intensity of the disulfiram-alcohol reaction is possible. A case of increased toxicity of temazepam has been described.
With simultaneous use with isoniazid, cases of the development of dizziness, depression are described; with caffeine - the excretion of caffeine from the body decreases; with metronidazole - develops acute psychosis, confusion; with omeprazole - a case of development of impaired consciousness and catatonia is described.
With simultaneous use with perphenazine, the development of psychotic symptoms cannot be excluded.
With simultaneous use, Teturam inhibits the metabolism and excretion of rifampicin.
With simultaneous use with phenazone, T1 / 2 of phenazone increases; with phenytoin - the effects of phenytoin are enhanced due to an increase in its concentration in the blood plasma, toxic reactions develop.
With simultaneous use with chlorzoxazone, the concentration of chlorzoxazone in the blood plasma increases; with chlorpromazine - may increase arterial hypotension.
Analogues of the drug Teturam
Structural analogues for the active substance:
- Antabuse;
- disulfiram;
- Lidevin;
- Esperal.
In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.
Instructions for use. Contraindications and release form.
INSTRUCTIONS
on the use of funds
TETURAM
Dosage forms
tablets 250mg
Pharmgroup
Means for the treatment of alcoholism
International non-proprietary name
Disulfiram
Vacation order
Released by prescription
Compound
The active substance is disulfiram.
pharmachologic effect
Anti-alcohol. Inhibits acetaldehyde dehydrogenase and delays the enzymatic biotransformation of alcohol at the stage of acetaldehyde. The accumulation of the latter in the body causes intoxication, which (since consciousness is preserved) is accompanied by severe sensations. Rapidly and completely absorbed in the gastrointestinal tract. It is metabolized quite intensively, recovering to diethyldithiocarbonate, excreted by the kidneys in the form of glucuronide, or decomposes to form diethylamine and carbon disulfide, which is excreted by the lungs.
Indications for use
Chronic alcoholism (relapse prevention, lack of therapeutic effect from other methods), chronic nickel intoxication.
Contraindications
Hypersensitivity, thyrotoxicosis, diabetes mellitus, pronounced cardiosclerosis, cerebral atherosclerosis, pre- and post-infarction conditions, aortic aneurysm, coronary insufficiency, stage II-III hypertension, decompensated cardiovascular diseases, pulmonary tuberculosis with hemoptysis, bronchial asthma , severe emphysema, erosion of the stomach, liver and kidney disease, mental illness, epileptiform syndrome, polyneuritis, glaucoma, pregnancy. Restriction on use: age over 60 years, peptic ulcer of the stomach and duodenum (in the acute stage), endarteritis, previously transferred psychosis while taking disulfiram.
Side effect
Metallic taste in the mouth, hepatitis, neuropsychiatric disorders, headache, polyneuritis of the lower extremities, pruritus, urticaria.
Interaction
Effects, incl. neurotoxic, enhance tricyclic antidepressants (amitriptyline), metronidazole, isoniazid, reduces (reaction to alcohol) - ascorbic acid. Reduces blood clotting against the background of indirect anticoagulants. Increases the toxicity of diphenin.
Overdose
Manifested by a coma, collapse, various neurological phenomena. Treatment is symptomatic.
Method of application and dosage
inside. The dose is selected individually, is usually 0.25-0.5 g / day. 8-10 tablets are implanted subcutaneously and intramuscularly.
special instructions
No information.
Storage conditions
List B. In a dry place.
Manufacturers
Tatkhimfarmpreparaty (Russia).
Teturam is one of the most popular drugs for the treatment of alcohol dependence. It refers to strong drugs and applies in cases where mild treatment did not give desired result. The drug has quite long list contraindications and possible undesirable consequences. Therefore, patients often look for other drugs with less side effects capable of replacing Teturam. Pharmacies offer many tablets for anti-alcohol therapy with a similar effect.
There are both analogues of Teturam, which have the same composition as it, and drugs similar in effect, suitable for the treatment of alcoholics at different stages of addiction. They should only be used as directed by a doctor. Illiterate use can harm the patient.
Similar tablets to Teturam:
- Stopethyl;
- disulfiram;
- Antabuse;
- Esperal;
- Antethyl;
- Kolma.
Drugs used in anti-alcohol therapy, with more soft effect(easy substitutes):
- Naltrexone;
- Proproten-100;
- Biotredin;
- Zorex;
- Alcodez.
Before use, you should take tests and carefully read the instructions to find out contraindications and undesirable consequences.
Colme
This is a liquid analogue of Teturam, also widely used for the treatment of alcoholism. active ingredient is cyanamide. This substance delays the biotransformation of ethanol in the liver. Compared with Teturam, the remedy is gentle. Its influence lasts a shorter amount of time and does not cause pressure surges.
Small doses of the drug are generally well tolerated by patients and do not cause complications. Therapy for advanced forms of alcoholism can be carried out long time, resulting in possible side effects. They are less pronounced than in Teturam, so they pass faster. These include:
- gastrointestinal disorders (diarrhea, nausea, vomiting),
- the occurrence of erosion in the esophagus;
- vascular thrombosis;
- violations of the liver;
- dermatitis.
Colme is available in the form of drops. They are colorless and odorless, which is a plus in cases of treatment without the knowledge of the patient. For standard treatment of alcoholism take 30-50 drops daily. However, the dosage is prescribed by the doctor depending on the severity of the specific case. The cost of the medicine is from 1200 to 1500 rubles for 4 ampoules.
The drug is widely used in the treatment of alcoholism in different stages. It is used in clinics for:
- treatment of chronic patients,
- withdrawal from drinking
- elimination of withdrawal syndrome.
In addition, it has detoxifying properties. The drug is a hepatoprotector that restores liver function. The agent enhances the removal of ethyl alcohol decay products from the body, prevents the occurrence of cirrhosis. Active substances contribute to the improvement of thinking, restore the connections of neurons in cells. These properties allow it to be used in complex therapy to restore the health of chronic alcoholics.
Available in tablets and in liquid form, as a solution for injection. To detoxify the body, the drug is injected into the bloodstream using droppers. For the treatment of alcoholism, take one tablet orally 2-3 times a day. Side effects include allergic reactions. The price in pharmacies is about 1500 rubles.
Naltrexone
It is used in anti-alcohol therapy at all stages of the disease. The principle of action of the drug is the blocking of opioid centers located in the brain. The drug does not apply to aversive drugs (causing conditioned reflexes). When it is used, there are no reactions accompanied by physical malaise, as in Teturam.
Among the undesirable consequences are:
- nausea;
- headache;
- stomach upset;
- weakness.
In rare cases, itching, rash, muscle pain. Some patients experienced irritability, sweating, decreased libido. The drug is available as an oily solution for intravenous administration. The treatment regimen is prescribed by the doctor individually. The price is about 750 rubles.
Esperal
This is an analogue of Teturam in injections and tablets. The active ingredient is disulfiram. The tool is intended to combat chronic alcoholism, to prevent relapse after treatment. Side effects are the same as those of Teturam. With long-term use, mental disorders may appear.
If during the treatment the patient takes alcohol, even in small quantities, the consequences will be as follows:
- severe pressure in the sternum, respiratory spasms;
- increased heart rate;
- rush of blood to the face, fever;
- headaches and muscle pain;
- decrease or increase in pressure;
- panic feeling of fear, disturbing thoughts.
In addition, the patient may develop psychosis, hallucinations with delusions, a state of persecution. The occurrence of these complications requires immediate medical assistance which cannot be provided at home.
It is necessary to carry out therapy with this agent in the clinic under the close supervision of a narcologist.
Contraindications:
- endocrine diseases;
- brain damage;
- tuberculosis;
- complex diseases of the cardiovascular system;
- disorders in the work of the lungs, respiratory tract;
- mental disorders;
- neuritis;
- epilepsy.
Before starting therapy, you should undergo an examination to determine the presence or absence of these diseases. This is a very important point that should not be neglected.
For treatment severe stages alcoholism remedy is taken orally one tablet during breakfast. During therapy, the dose is gradually reduced. For a sustainable effect, Esperal is drunk regularly, up to three years. As intramuscular injections used for coding for 1-3 years. The cost depends on the form of release and the amount of the substance and starts from 1000 rubles.
Proproten-100
Homeopathic medicine. The active substance is antibodies to protein compounds S-100, located in the brain. It is intended to relieve withdrawal symptoms, is used as aid in complex anti-alcohol therapy. The drug eliminates the symptoms associated with the effect of withdrawal after prolonged use of alcohol. Its use has a positive effect on the patient's psyche, normalizes sleep, reduces aggression. 
Side effects are not observed, except for intolerance to the components of the drug. There are also no contraindications. The price ranges from 100-200 rubles.
Biotredin
The main substances of the drug are pyridoxine (vitamin B) and L-threonine. It is intended for the treatment of chronic alcoholism in combination with other drugs, relieving withdrawal symptoms. Reduces craving for alcohol, removes irritability, normalizes metabolism.
The drug is taken in a course lasting up to 14 days during an exacerbation of the disease. The dosage is determined by the attending physician. No contraindications or adverse effects were observed. Should not be taken with antidepressants.
Zorex
An effective drug used to reduce cravings for alcohol and recover from drunken conditions. The composition includes the substance unithiol, which has a detoxifying effect. The medicine also contains a calcium salt. pantothenic acid, regulating calcium-phosphorus metabolism in the body.
To reduce dependence, take one tablet twice a day, before meals. When removing hangover syndromes and withdrawal symptoms, drink 1 capsule in the morning and during the day. side effects No, except for the appearance of an allergy to the components of the drug. Contraindications are severe kidney and liver diseases.
To develop an aversion to alcohol, doctors use the drug Teturam, which, when interacting with even a small amount of alcohol, causes convulsions, dilates blood vessels and leads to nausea. The use of the drug is justified in cases of treatment of alcoholism. The principle of the drug is that it inhibits the acetaldehyde dehydrogenase enzymes involved in the metabolism of ethanol.
The drug based on the substance disulfiram enjoys well-deserved popularity and is able to bring real benefit subject to the rules of use. The action of the drug is based on the principle of "knock out a wedge with a wedge", so it should be used with caution, following the instructions. You need to realize that Teturam contributes to short-term severe intoxication of the body, which creates in the drinker conditioned reflex: alcohol is pain and suffering. The drug is able to influence the behavior of the addict much more than the persuasion of loved ones.
Related articles Pills for alcohol addiction Coding drugs for alcohol addiction Pills for alcohol addiction without the knowledge of the patient
Composition and form of release
The drug is produced in the form of tablets having a flat-cylindrical shape. The color of the drug is white, sometimes with a yellow-greenish tint, there is no smell. The drug is intended for oral administration. Tablets are packaged in blisters, which are placed in carton boxes for sale through pharmaceutical networks. The volume of the active substance can be 100, 150, 200 mg.
Pharmacodynamics and pharmacokinetics
The agent affects the metabolism of ethyl alcohol that has entered the body, as a result of which the concentration of toxic decomposition products of alcohol in the tissues increases. The person begins to feel a flush of blood to the face, the urge to nausea ( possible complications up to vomiting), drops blood pressure. The peak of the therapeutic effect is reached after 12 hours after ingestion and can last up to two weeks.
Absorption of the drug in the stomach and intestines is at least 70% and can reach up to 90%. In the process of metabolism, which occurs in a short time, Teturam is reduced to dithiocarbamate, which is excreted from the body in the form of glucuron conjugate. Part of the dithiocarbamate can be transformed into diethylamine and carbon sulfite, which can be excreted through the lungs, the rest is excreted in the urine.
Indications for use
The tool is used as effective method prevention of chronic alcoholism. Teturam can be used as a drug that guarantees the absence of relapses during the main treatment with other specific methods. The tool can be used by relatives both in secret from an alcoholic, and used by a drinker consciously. Active substance Teturama-disulfiram is an antidote for nickel, for this reason it can be used for detoxification in case of poisoning with this metal.
Method of application and dosage
According to the instructions, Teturam is taken orally by mouth. Dosages should be in the range of 150-500 mg per day. The specific dosage and regimen are determined individually by the narcologist, depending on the patient's condition. After 8-10 days, an experimental test for the action of the agent is carried out. The test produces a psychological effect. After taking the pill, the patient is given 30 mg of vodka. The strength of the reaction is a dosage adjustment factor. After the revision, a second test is carried out after 3-4 days. The maintenance dose is 150-200 mg per day.
How to take Teturam on your own
Often the drug is used by patients on their own or through loved ones. This is an acceptable practice, but it must be preceded by a mandatory consultation with a doctor with the appointment of a regimen. The doctor has knowledge of the risks of using the drug against the background of the patient's pathologies and health status. Neglecting these factors can be harmful. According to doctors, 1-3 tablets per day (150-450 mg) are prescribed. The process of admission should be accompanied by periodic supervision by a doctor.
The duration of the course of treatment
The duration of the main course of therapy is 4-6 weeks. The maintenance dose can last from one to three years. The decision on specific timing should be made by the responsible doctor. The decisive influence on the period of treatment is individual characteristics sick. The duration and reliability of therapy largely depend on the complexity of the approach. Measures to social adaptation the patient fixes the effect achieved with the help of Teturam. Possible implantation of tablets.
Teturam and alcohol
The therapeutic effect is achieved by suppressing the ability of the liver to produce acetaldehyde dehydrogenase, an enzyme that breaks down alcohol into water and carbon dioxide suspended at an intermediate stage of acetaldehyde. This substance is a toxic poison, which negative impact stronger than alcohol 20-30 times. The concentration of acetaldehyde accumulates in the tissues and causes a number of manifestations in a person under alcohol dependence, as a result of which he is forced to stop the process of drinking alcoholic beverages.
drug interaction
Teturam tablets should not be combined with certain medicines due to negative reactions. Example of combinations and effects:
- according to reviews, anticoagulants, coumarin derivatives, warfarin increase the risk of bleeding;
- disulfiram disrupts the metabolism of liver enzyme inhibitor drugs;
- tricyclic antidepressants, phenothiazine derivatives increase the risk of side effects;
- Buspirone can cause mania when combined with Teturam;
- the drug reduces the clearance of Desipramine, Imipramine;
- Amitriptyline enhances the therapeutic effect of the drug, but the toxicity of the drug itself increases in parallel;
- Disulfiram increases the plasma concentration of Diazepam and Chlordiazepoxide, their administration is accompanied by dizziness, Diazepam also reduces the intensity of the reaction with ethanol, there are cases of increased toxicity of Temazepam;
- Isoniazid can cause dizziness, depression, caffeine - a decrease in excretion from the body, Metronidazole - acute psychosis and confusion, Omeprazole - impaired consciousness and catatonia;
- Perphenazine can lead to psychotic symptoms;
- Disulfiram inhibits the metabolism and excretion of Rifampicin, increases the withdrawal period of Phenazone, enhances the effect of Phenytoin, increases the concentration of Chlorzoxazone, enhances the effect of arterial hypotension Chlorpromazine.
Side effects of Teturama
The most common side effect of the drug is a teturam-like effect (total alcohol intolerance due to alcohol biotransformation), which cannot be considered an achievement, since alcohol is produced in minimal doses. human body default. Others negative reactions from taking the medication are:
- metallic taste in the mouth, hepatitis, confusion;
- polyneuritis of the lower extremities, memory disorders, headache;
- neuropsychiatric disorders, allergic reactions in the form of skin rash and itching;
- collapse due to the use of alcohol, heart rhythm disturbances, angina pectoris, myocardial infarction, cerebral edema.
Contraindications
The use of Teturam for alcoholism is prohibited for certain groups of patients with specific conditions, as well as those undergoing therapy with certain drugs:
- severe course cardiovascular diseases;
- diabetes;
- epilepsy;
- neuropsychiatric diseases;
- combination with alcohol, phenytoin, isoniazid, metronidazole;
- pregnancy, lactation, liver disease;
- hypersensitivity to components.
Terms of sale and storage
The medicine Teturam is dispensed by prescription, stored for four years, provided that the temperature regime is not higher than 25 degrees.
Teturam analogue
It is permissible to use analogues of a drug that have an identical active substance or providing similar pharmacological effects. Analogues of the drug are presented below:
- Esperal;
- disulfiram;
- Antabuse;
- Tetlong;
- Alcodez;
- Liveria;
- Antakson;
- Vivitrol;
- Naltrex;
- Naltrexin;
- Biotredin;
- Colme;
- Naxon.
Teturam price
When buying Teturam, it is recommended to check the price monitoring, in different pharmacies and pharmaceutical chains, the drug is sold at different prices. The price level of the drug depends on the manufacturer and the seller's margin. The average prices for the drug are indicated in the table.