Arbidol instructions for use, contraindications, side effects, reviews. Children's Arbidol: instructions for use Arbidol contraindications

Children are more susceptible to viral diseases. The likelihood of developing the disease increases when the child begins to attend kindergarten or school. In addition, viral infections appear in young patients during the cold season or during epidemics. This is due to the fact that the baby’s body continues to develop, and the immune system weakens during the off-season. It is important to treat the child correctly to prevent complications. For this purpose, it is recommended to use Arbidol at the first symptoms of the disease.

An effective drug that demonstrates an antiviral effect is called Arbidol. Most often it is used for influenza and respiratory diseases. In addition, the medication helps prevent viral infections during epidemics. Arbidol strengthens the immune system and shows antioxidant protection. The drug is available in various dosage forms and is well tolerated by patients.

Composition and effect on the body

Arbidol for children is available in tablets, capsules and powder. As a rule, children are prescribed tablets to treat viral diseases. Although the quantity active substance in capsules and pills is the same. However, the second dosage form is more convenient for young patients. But if the child is already old enough, then he can take capsules. The main thing is to follow the dosage prescribed by the pediatrician.

The suspension looks like a cream-colored powder, which is diluted with water before use. This syrup is allowed to be taken by patients over 2 years of age. The main component of the drug is umifenovir. In addition, the medicine contains additional substances: MCC, pyrogenic silicon dioxide, starch, calcium sterol, povidone, etc.

To understand how Arbidol works, you need to start from the moment the child becomes infected. When the virus enters the body, it provokes the production of hemagglutinin (a special protein). With its help, the pathogenic agent attaches to receptors on the surface of cells, causing inflammatory reactions. For influenza, acute respiratory infections pathogen affects the respiratory tract, ENT organs.

Viruses multiply in the body, causing inflammation to grow. As a result, the patient develops a cough, rhinitis, swelling of the mucous membranes, and a sore throat. Arbidol blocks the production of hemagglutinin, which damages body tissue. That is, the drug protects cells from the action of a pathogenic agent, keeping it at outer shell until it ends life cycle. As a rule, after 3–4 days the virus dies.

Arbidol helps prevent influenza or acute respiratory infections during mass illnesses. The therapeutic effect is due to the fact that the medication blocks the action of the pathogenic microorganism immediately after its penetration into the inner shells. The drug is prescribed to children when the body's immune strength is reduced.

Thus, Arbidol demonstrates the following effects:

• antiviral;
• immunomodulatory;
• antioxidant;
• detoxification;
• reduces the likelihood of complications viral infections.

In addition, with timely and regular use of Arbidol, chronic diseases are less likely to worsen.

Appointment of Arbidol

The drug treatment regimen is determined by the pediatrician, taking into account age and clinical picture.

Arbidol is prescribed to children if they have the following diseases:

• Influenza (type A, B), respiratory diseases.
• Viral infections that are accompanied by inflammation of the bronchi and lungs.
• After surgery, to reduce the likelihood of viruses entering the body.
• Diseases of viral etiology with a chronic course (to reduce the frequency of exacerbations of the disease).

According to the instructions for use, Arbidol helps not only to cure, but also to prevent viral infections.

Tablet dosage

A single dose of medication for patients of different ages:

• 3 – 6 years – 50 mg;
• 7 – 12 years – 100 mg;
• from 13 years – 200 mg.

Tablets are sold with different dosages umifenovir – 50 or 100 mg. Your doctor will help you choose the appropriate concentration for your child.

Arbidol treatment regimens for different diagnoses:

• For the prevention of influenza, acute respiratory infections - a single dose, treatment lasts 10 - 14 days.
• To prevent viral infections during mass diseases - a standard portion for 20 days.
• For flu or mild colds – 4 single doses per 24 hours for 5 days.
• For influenza or acute respiratory infections with complications, a single dose is taken four times a day for 5 days. Then take 1 tablet every 7 days for 1 month.

The final dosage of the medicine for children will be determined by the pediatrician.

Application of capsules

A single dose of the drug in capsule form for children is no different. Patients from 3 to 6 years old take 1 piece with a concentration of umifenovir 50 mg, children from 7 to 12 years old - 1 capsule of 100 mg, and patients over 13 years old - 2 capsules of 100 mg.

Treatment regimens for diseases of viral origin:

• For flu and colds, children over 3 years old drink 1 capsule four times, over 7 years old - 1 capsule (100 mg), over 13 years old - 2 pieces (100 mg each) with the same frequency of use. Treatment lasts 5 days.
• To cure influenza, acute respiratory infections with complications need to take a standard dose four times a day for 5 days. Then 1 dose of the medicine is taken 1 time every 7 days for 1 month.
• To prevent viral infections, children are prescribed 1 serving of capsules twice every 7 days. Total duration therapy – 3 weeks.

If the child has been in contact with a sick person, then a single dose is taken 1 time in 14 days.

Suspension for children

The suspension is sold in pharmacies less often than others dosage forms. The finished syrup is stored on the bottom shelf of the refrigerator for no longer than 10 days. After this period, the medicine must not be used. Patients over 2 years old can use the solution for medical reasons.

To prepare the syrup, pour 30 ml into a bottle with powder warm water after boiling. Then you need to close the lid and shake the liquid so that the contents dissolve. Then pour a little more water into the bottle so that its level reaches 100 ml, close it and shake again. After this procedure, the suspension is ready.

A single dose depends on the age of the child:

• 2 – 6 years – 10 ml;
• 7 – 12 years – 20 ml;
• from 13 years – 40 ml.

The solution is taken according to the following scheme:

• To prevent colds - a single dose twice every 7 days. Duration of treatment – ​​20 days.
• To prevent viral infections after contact with a patient - 1 dose within 14 days.
• To cure the flu, acute respiratory infections - a single serving four times. Therapy lasts 5 days.

The final dose of the medicine will be determined by the pediatrician, taking into account age and individual characteristics the child's body.

Restrictions and contraindications

Arbidol is well tolerated by children and rarely provokes negative reactions. The drug in the form of tablets and capsules is prohibited for use by patients under three years of age (including up to one year). The suspension is not recommended for children under 2 years of age. In addition, Arbidol is contraindicated in case of intolerance to its components.

For renal, hepatic, cardiac or vascular insufficiency the child can take Arbidol, but his condition must be monitored by a pediatrician. If the rules of use are violated or there are contraindications, a rash appears on the skin, itching, nettle fever, nausea. If such symptoms appear, stop taking Arbidol and consult your doctor.

Cost of the drug

You can find Arbidol in all pharmacies in the country; its cost depends on the dosage form and volume:

• Powder for making syrup (25 ml) costs from 330 to 350 rubles.
• Pills (50 mg) 10 pcs. - on average 150 rubles.
• The cost of 100 mg tablets (the same quantity) is 190 rubles.
• For 10 capsules (50 mg) you need to pay 180 rubles.
• Gelatin-coated pills (100 mg) 10 pcs. cost about 240 rubles.

If necessary, Arbidol can be replaced with a cheaper medicine with a similar effect.

Alternative medicines

If there are contraindications, the child is given drugs with a similar therapeutic effect. Popular analogues of Arbidol for children:

• Ingavirin helps fight influenza viruses (type A, B). This medicine is more effective than Arbidol, but has more side effects, so before using it you must obtain the approval of a pediatrician.
• used for the prevention and treatment of viral infections. Stimulates the production of interferon and helps the body fight pathogenic agents. Designed for children over 3 years old.
• Aflubin is another analogue of Arbidol, which provokes the synthesis of interferon. After taking the drug, the swelling of the mucous membrane decreases, the removal of sputum accelerates, the temperature normalizes, and the body is cleansed of toxins. For patients up to 12 months, a suspension is used.
• Remantadine does not strengthen the immune system, but it copes well with viruses. The medication is contraindicated in children with liver failure and patients younger than 12 months.
• is a homeopathic medicine for the prevention and treatment of influenza and colds. With regular use, the likelihood of dangerous complications(bronchitis, pneumonia).
• Immunal increases immunity, prevents viral diseases, and accelerates recovery in the presence of infection. The drug is contraindicated only if you are allergic to its components. Suitable for patients up to 12 months.

Thus, Arbidol for children is effective, and if the treatment rules are followed, safe drug. Before using it, consult a pediatrician who will select a treatment regimen and dosage. If a child, after taking Arbidol, develops side effects, then abandon it and consult a doctor.

The contents of the capsules are a mixture containing granules and powder from white to white with a greenish-yellowish or creamy tint.

Active substance:

Umifenovir (umifenovir hydrochloride monohydrate (arbidol) in terms of umifenovir hydrochloride) – 100 mg.

Regimen and dosage

Treatment
4 times a day, 5 days

Post-exposure prophylaxis
Once a day, 10–14 days

Seasonal prevention
2 times a week, 3 weeks

• 6-12 years single dose 100 mg

• 12 years and older single dose 200 mg

Registration number: P N003610/01

Trade name: Arbidol ®

International nonproprietary name: umifenovir

Dosage form: capsules

Composition per capsule

Active ingredient: umifenovir hydrochloride monohydrate (in terms of umifenovir hydrochloride) – 100 mg.

Excipients: core: potato starch - 30.14 mg, microcrystalline cellulose - 55.76 mg, colloidal silicon dioxide (Aerosil) - 2.0 mg, povidone K 25 (kollidon 25) - 10.1 mg, calcium stearate - 2 .0 mg.

Hard gelatin capsules No. 1:

Body: titanium dioxide (E 171) – 2.0000%, gelatin – up to 100%.

Cap: titanium dioxide (E 171) – 1.3333%, sunset yellow dye (E 110) – 0.0044%, quinoline yellow (E 104) – 0.9197%, gelatin – up to 100%.

Description

Hard gelatin capsules No. 1. Frame white, cap yellow. The contents of the capsules are a mixture containing granules and powder from white to white with a greenish-yellowish or creamy tint.

Pharmacotherapeutic group: antiviral agent

ATX code: J05AX13

Pharmacological properties

Pharmacodynamics. Antiviral agent. Specifically suppresses in vitro influenza viruses A and B (Influenzavirus A, B), including highly pathogenic subtypes A(H1N1)pdm09 and A(H5N1), as well as other viruses that cause acute respiratory viral infections (ARVI) (coronavirus associated with severe acute respiratory syndrome (SARS), rhinovirus (Rhinovirus), adenovirus (Adenovirus), respiratory syncytial virus (Pneumovirus) and parainfluenza virus (Paramyxovirus)). By mechanism antiviral action belongs to fusion inhibitors, interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect and increases the body's resistance to viral infections. It has interferon-inducing activity - in a study on mice, the induction of interferons was noted after 16 hours, and high titers interferons remained in the blood for up to 48 hours after administration. Stimulates cellular and humoral immune responses: increases the number of lymphocytes in the blood, especially T-cells (CD3), increases the number of T-helpers (CD4) without affecting the level of T-suppressors (CD8), normalizes the immunoregulatory index, stimulates the phagocytic function of macrophages and increases the number of natural killer (NK) cells.

Therapeutic effectiveness for viral infections is manifested in a decrease in the duration and severity of the disease and its main symptoms, as well as in a decrease in the incidence of complications associated with viral infection and exacerbations of chronic bacterial diseases.

In the treatment of influenza or ARVI in adult patients, a clinical study showed that the effect of the drug Arbidol ® in adult patients is most pronounced in the acute period of the disease and is manifested by a reduction in the time for resolution of symptoms of the disease, a decrease in the severity of manifestations of the disease and a reduction in the time for elimination of the virus. Therapy with Arbidol ® leads to a higher rate of relief of disease symptoms on the third day of therapy compared to placebo. 60 hours after the start of therapy, the resolution of all symptoms of laboratory-confirmed influenza was more than 5 times higher than in the placebo group.

A significant effect of the drug Arbidol ® on the rate of elimination of the influenza virus was established, which, in particular, was manifested by a decrease in the frequency of detection of viral RNA on the 4th day.

Refers to low-toxic drugs (LD50 > 4 g/kg). Doesn't provide any negative impact on the human body when oral administration in recommended doses.

Pharmacokinetics. Quickly absorbed and distributed throughout organs and tissues. The maximum concentration in blood plasma is reached after 1.5 hours. Metabolized in the liver. The half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in small amounts by the kidneys (0.12%). During the first day, 90% of the administered dose is eliminated.

Indications for use

Prevention and treatment in adults and children: influenza A and B, other acute respiratory viral infections.

Complex therapy for recurrent herpetic infection.

Prevention of postoperative infectious complications.

Complex therapy of acute intestinal infections rotavirus etiology in children over 6 years of age.

Contraindications

Hypersensitivity to umifenovir or any component of the drug; childhood up to 6 years old. First trimester of pregnancy. Breastfeeding period.

With caution:

Second and third trimesters of pregnancy

Use during pregnancy and breastfeeding

Not found in animal studies harmful effects on the course of pregnancy, development of the embryo and fetus, labor and postnatal development. The use of Arbidol ® in the first trimester of pregnancy is contraindicated. In the second and third trimester of pregnancy, Arbidol ® can only be used for the treatment and prevention of influenza and if the expected benefit to the mother exceeds potential risk for the fetus. The benefit/risk ratio is determined by the attending physician.

It is not known whether Arbidol ® penetrates into breast milk in women during lactation. If it is necessary to use the drug Arbidol ®, you should stop breastfeeding.

Directions for use and doses

Inside, before meals.

Single dose of the drug (depending on age):

Dosage regimen (depending on age):

Indication	Dosage regimen
For children over 6 years of age and adults:
Nonspecific prevention during an epidemic of influenza and other acute respiratory viral infections	in a single dose 2 times a week for 3 weeks
Nonspecific prophylaxis in direct contact with patients with influenza and other acute respiratory viral infections	in a single dose 1 time per day for 10-14 days
Treatment of influenza and other acute respiratory viral infections
Complex therapy for recurrent herpes infection	in a single dose 4 times a day (every 6 hours) for 5-7 days, then a single dose 2 times a week for 4 weeks
Prevention of postoperative infectious complications	in a single dose 2 days before surgery, then on the 2nd and 5th days after surgery
For children over 6 years of age:
Complex therapy of acute intestinal infections of rotavirus etiology	in a single dose 4 times a day (every 6 hours) for 5 days

Use the drug only according to the indications, method of administration and in the doses indicated in the instructions.

The drug should be taken from the moment the first symptoms of influenza and other acute respiratory viral infections appear, preferably no later than 3 days from the onset of the disease.

If after using the drug Arbidol ® for three days in the treatment of influenza and other acute respiratory viral infections, the severity of the symptoms of the disease persists, including high temperature(38 °C or more), then you need to consult a doctor to assess the validity of taking the drug.

When treating influenza and ARVI, concomitant symptomatic therapy, including taking antipyretic drugs, mucolytics and local vasoconstrictors.

Side effect

The drug Arbidol ® is a low-toxic drug and is usually well tolerated.

Side effects are rare, usually mild or moderate and transient.

The frequency of adverse drug reactions is determined in accordance with the WHO classification: very often (with a frequency of more than 1/10), often (with a frequency of at least 1/100, but less than 1/10), infrequently (with a frequency of at least 1/1000, but less than 1/100), rare (with a frequency of at least 1/10,000, but less than 1/1000), very rare (with a frequency of less than 1/10,000), frequency unknown (cannot be determined from the available data).

Violations by immune system: rarely - allergic reactions.

If any of the side effects indicated in the instructions get worse, or you notice any other side effects, not listed in the instructions, inform your doctor.

Overdose

Not marked.

Interaction with other drugs

When assigned with others medicines no negative effects were noted.

No special clinical studies have been conducted to study the interactions of the drug Arbidol ® with other drugs.

Information about the presence of undesirable interactions with antipyretic, mucolytic and local vasoconstrictor drugs in conditions clinical trial were not identified.

Special instructions

It is necessary to follow the regimen and duration of taking the drug recommended in the instructions. If you miss one dose of the drug, the missed dose should be taken as early as possible and continue taking the drug according to the started regimen. If, after using the drug Arbidol ® for three days in the treatment of influenza and other acute respiratory viral infections, the severity of the symptoms of the disease, including high temperature (38 ° C or more), then you must consult a doctor to assess the validity of taking the drug.

Instructions for use:

Arbidol is medicinal product, which belongs to the group of antiviral and immunomodulatory drugs.

Release form

Arbidol is available in the form of yellow tablets or capsules, in the middle of the capsule there are granules and powder, the color of this mixture varies from pure white to white with a cream or greenish-yellow tint.

Arbidol is available in capsules with the active ingredient of 50 and 100 mg and in tablets with the active ingredient of 100 or 200 mg. Arbidol for children is approved for use from three years of age, since in more early age It is difficult for children to take medications in tablets and capsules. Previously, Arbidol for children was used from the age of two years.

Pharmacological action

Arbidol refers to antiviral drugs, acts as an immunomodulator. Shows anti-influenza effect. It has a negative effect on influenza viruses type A and B, as well as the SARS virus (severe acute respiratory syndrome), suppressing them.

Prevents contact and penetration of the virus into the cells of the body. Suppresses the coupling of the fatty membrane of the virus and cell membranes, strengthens the immune system, and increases the body’s resistance to viruses.

Reduces the incidence of complications after viral infections and exacerbation of chronic bacterial infections. The use of Arbidol for viral infections helps reduce intoxication and symptoms of the disease, and reduce the time of illness. The drug does not have a negative effect on the human body when taken in recommended doses.

Indications for use of Arbidol

According to the instructions, Arbidol is effective for the following diseases:

Flu types A and B;

TORS (severe acute respiratory syndrome);

Viral infections with complications (bronchitis and pneumonia);

Repeated immunodeficiency states;

Chronic bronchitis, pneumonia and recurrent herpes infections in chronic form(in combination with other drugs);

As a prophylactic agent to prevent infectious complications after operations.

In combination with other drugs, Arbidol for children is prescribed for intestinal infections of rotavirus nature.

Method of administration of Arbidol and dose

According to the instructions for Arbidol, the drug must be taken orally after meals.

A single dose for adults and children over twelve years old is 200 mg, for children aged six to twelve years – 100 mg, for children aged three to six years – 50 mg.

The use of Arbidol as a prophylaxis

1. In contact with a sick person (flu and ARVI):

Adults and children over 12 – 200 mg/day;

Children 3-6 years old – 50 mg/day.

Arbidol is taken once a day, the course of treatment ranges from 10 days to two weeks.

2. To prevent relapse chronic bronchitis and herpes infection during the spread of influenza and ARVI :

Children 6-12 years old – 100 mg/day;

Children 3-6 years old – 50 mg/day.

Arbidol must be taken 2 times a week, the course of treatment is three weeks.

3. To prevent SARS in direct contact with a sick person:

Adults and children over 12 years of age – 200 mg/day;

Children 6-12 years old – 100 mg/day;

The drug is taken once a day, the course of treatment is 12-14 days.

4. To prevent infection after surgery:

Adults and children over 12 years of age – 200 mg/day;

Children 6-12 years old – 100 mg/day;

Children 3-6 years old – 50 mg/day.

In this case, Arbidol is used two days before the intended operation, on the second and fifth days after it.

The use of Arbidol as a treatment

1. Flu and ARVI without complications:

Adults and children over 12 years of age - 200 mg 4 times a day;

Children 6-12 years old – 100 mg 4 times a day;

Children 3-6 years old - 50 mg 4 times a day.

The course of treatment is 5 days.

2. Flu and ARVI with complications (bronchitis, pneumonia):

Adults and children over 12 years old - 200 mg 4 times per day, 5 days, then 200 mg 1 time (in 7 days), course 4 weeks.

Children 6-12 years old - 100 mg 4 times/day, then 100 mg 1 time/7 days, course 4 weeks.

Children 3-6 years old - 50 mg 4 times/day, 5 days, then 50 mg 1 time/7 days, course 4 weeks.

When taking the drug four times a day, the time between doses is 6 hours.

3. For the treatment of SARS:

Adults and children over 12 years old - 200 mg 2 times a day, course 8-10 days.

4. In combination with other drugs for the treatment of chronic bronchitis and recurrent herpetic infections:

Adults and children over 12 years old - 200 mg 4 times/day, 5-7 days, then 200 mg 2 times/7 days, course 4 weeks.

Children 6-12 years old - 100 mg 4 times/day, 5-7 days, then 100 mg 2 times/7 days, course 4 weeks.

Children 3-6 years old - 50 mg 4 times/day, 5-7 days, then 50 mg 2 times/7 days, course 4 weeks.

When taking the drug four times a day, the time between doses is 6 hours.

5. In combination with other drugs for acute intestinal infections of rotavirus nature:

Children over 12 years old - 200 mg 4 times a day, 5 days.

Children 6-12 years old - 100 mg 4 times a day, 5 days.

Children 3-6 years old - 50 mg 4 times a day, 5 days.

Side effects

According to the instructions for Arbidol, the drug is quite well tolerated, in rare cases it is possible to develop an allergy to the components of Arbidol.

Contraindications

According to the instructions, Arbidol is contraindicated in case of sensitivity to the components of Arbidol, as well as in children under three years of age.

Pregnancy and breastfeeding

There is no data on the use of Arbidol during pregnancy and feeding a child.

More information

According to the instructions, Arbidol does not affect the ability to drive vehicles or operate dangerous machinery.

Arbidol's analogs

Arbidol analogues mean drugs that have the same active substance, but are sold under other names.

Analogues of Arbidol include the following drugs:

Proteflazid;

Ferrovir;

Detoxopyrol;

Armenicum;

Engystol.

Before using Arbidol analogue, be sure to consult with your doctor.

LSR-003900/07

Trade name of the drug

Arbidol®

International nonproprietary name

Umifenovir

Chemical name

Ethyl 6-bromo-5-hydroxy-1-methyl-4-dimethylaminomethyl-2-phenylthiomethylindole-3-carboxylic acid hydrochloride monohydrate.

Dosage form

Tablets, coated film-coated.

Other dosage forms Arbidol

Description

Film-coated tablets from white to off-white with a creamy tint, round, biconvex. On the fracture it is white to white with a greenish-yellowish or creamy tint.

Composition per tablet

Active substance:

umifenovir (umifenovir hydrochloride monohydrate (arbidol) in terms of umifenovir hydrochloride) - 50 mg or 100 mg.
Excipients:
core: potato starch - 31.860 mg or 63.720 mg, microcrystalline cellulose - 57.926 mg or 115.852 mg, povidone-K30 (kollidon 30) - 8.137 mg or 16.274 mg, calcium stearate - 0.535 mg or 1.070 mg, croscarmellose sodium (primellose) 1,542 mg or 3.084 mg; Shell: gypromallosis (hydroxypropylmethyl cellulose) - 4.225 mg or 8.450 mg, dioxide titanium - 1.207 mg or 2.415 mg, macrogol -4000 (polyethylene glycol -4000) - 0.471 mg or 0.942 mg, polysorbas -80 (twin -80) - 0.097 mg or 0.193 mg (for dosages 50 mg and 100 mg)

or
Advantia™ Prime 390035ZP01 (Advantia™ Prime 390035ZP01) - 6,000 mg [Hypromellose (hydroxypropyl methylcellulose) - 4.225 mg, titanium dioxide - 1.207 mg, macrogol-4000 (polyethylene glycol-4000) - 0.471 mg, polysorbate-8 0 (twin-80) - 0.097 mg] - for a dosage of 50 mg

or
Aquarius PrimeVAR318008 White -6.000 mg [Hypromellose (hydroxypropyl methylcellulose) - 4.225 mg, titanium dioxide - 1.207 mg, macrogol-4000 (polyethylene glycol-4000) -0.471 mg, polysorbate-80 (Tween-80) - 0, 097 mg] - for a dosage of 50 mg.

Pharmacotherapeutic group

antiviral agent.

ATX code

Pharmacological properties

Pharmacodynamics.

Antiviral agent. Specifically suppresses influenza A and B viruses, coronavirus associated with severe acute respiratory syndrome (SARS). According to the mechanism of antiviral action, it belongs to fusion inhibitors, interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. Has a moderate immunomodulatory effect. It has interferon-inducing activity, stimulates humoral and cellular immune responses, the phagocytic function of macrophages, and increases the body's resistance to viral infections. Reduces the incidence of complications associated with viral infection, as well as exacerbations of chronic bacterial diseases. Therapeutic effectiveness for viral infections is manifested in a decrease in the severity of general intoxication and clinical phenomena, a reduction in the duration of the disease, and a decrease in the risk of complications.
Refers to low-toxic drugs (LD50 > 4 g/kg). Does not have any negative effects on the human body when administered orally in recommended doses.
Pharmacokinetics.

Quickly absorbed and distributed throughout organs and tissues. The maximum concentration in blood plasma when taken at a dose of 50 mg is achieved after 1.2 hours, at a dose of 100 mg - after 1.5 hours. Metabolized in the liver. The half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in small amounts by the kidneys (0.12%). During the first day, 90% of the administered dose is eliminated.

Indications for use

Prevention and treatment in adults and children:

• influenza A and B, ARVI, severe acute respiratory syndrome (SARS) (including those complicated by bronchitis, pneumonia);
• secondary immunodeficiency states;
• complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection.
• Prevention of postoperative infectious complications and normalization of immune status.
• Complex therapy of acute intestinal infections of rotavirus etiology in children over 3 years old.

Contraindications

Hypersensitivity to the drug, children under 3 years of age.

Directions for use and doses

Inside, before meals. Single dose: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg (2 tablets of 100 mg or 4 tablets of 50 mg).
For nonspecific prophylaxis:
- in direct contact with patients with influenza and other acute respiratory viral infections:
children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 1 time per day for 10 -14 days;
- during an epidemic of influenza and other acute respiratory viral infections, to prevent exacerbations of chronic bronchitis, relapse of herpes infection:
children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 2 times a week for 3 weeks.
- for the prevention of SARS (in contact with a patient): adults and children over 12 years of age are prescribed 200 mg once a day for 12-14 days.
- prevention postoperative complications:
children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 2 days before surgery, then 2 - 5 days after surgery.
For treatment:
- influenza, other acute respiratory viral infections without complications:
children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5 days;
- influenza, other acute respiratory viral infections with the development of complications (bronchitis, pneumonia, etc.):
children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5 days, then a single dose 1 time per week for 4 weeks. Severe acute respiratory syndrome (SARS):
adults and children over 12 years old - 200 mg 2 times a day for 8-10 days.
IN complex treatment chronic bronchitis, herpetic infection:
children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5 to 7 days, then a single dose 2 times a week within 4 weeks. Complex therapy of acute intestinal infections of rotavirus etiology in children over 3 years of age:
from 3 to 6 years - 50 mg, from 6 to 12 years - 100 mg, over 12 years - 200 mg 4 times a day (every 6 hours) for 5 days.

Side effect

Rarely - allergic reactions.

Overdose

Not marked.

Interaction with other drugs

When prescribed with other drugs, no negative effects were noted.

Special instructions

Does not exhibit central neurotropic activity and can be used in medical practice V for preventive purposes in practically healthy individuals of various professions, incl. requiring increased attention and coordination of movements (transport drivers, operators, etc.).

Release form

Film-coated tablets 50 mg, 100 mg.
10 tablets in a blister pack.
10, 20, 30 or 40 tablets in a polymer jar.
1, 2, 3 or 4 blister packs or a polymer jar of 10, 20, 30 or 40 tablets along with instructions for use in a cardboard pack.

Other number of doses (volume) in the package Arbidol Tablets

Best before date

3 years - for a dosage of 50 mg.
2 years - for a dosage of 100 mg.
Do not use after the expiration date stated on the package.

Storage conditions

At a temperature not higher than 25 °C.
Keep out of the reach of children.

Arbidol is a drug that prevents the emergence and development of viruses in the body of groups A and B. It helps strengthen the immune system and protect the body from the manifestations of influenza through the manifestation of humoral and cellular reactions. Taking the medicine helps reduce complications after suffering from acute respiratory viral infections and acute respiratory infections. The product has therapeutic effect, due to which the duration of the disease decreases, which means the body recovers quickly.

Composition and release form

Available in capsules with 50 mg of active substance. The drug is produced in packages of 10, 20 and 40 pieces or in cans.

Arbidol comes in capsules with different markings and colors:

• No. 10 – yellow. The dose is 50 milligrams.
• No. 1 - white with a dose of one hundred mg.

Inside the capsules there is a powdery substance that has different color shades from white to greenish.

Composition of Arbidol capsules

• Main components: Arbidol hydrochloride in an amount of 100 mg.
• excipients : potato starch, microcrystalline cellulose, colloidal silicon dioxide, povidone.
• Capsule shell consists of: titanium dioxide, dyes, acetic acid, gelatin.

Indications for use of Arbidol

When taking the drug, the following indications are used:

• Treatment of group A and B viruses
• Severe form of ARVI.
• Secondary immunodeficiencies.
• Therapy in the complex of consequences of bronchitis, pneumonia or herpes.
• Prophylactic for complications in postoperative period.
• Normalization of immunity.

Contraindications

Instructions for use prohibit Arbidol in the following cases:

• Hypersensitivity to individual components of the drug.
• Age up to 3 years.
• For diseases cardiovascular system, as well as renal-hepatic.
• Should be taken with caution during pregnancy and lactation.

Side effects

TO side effects The drug may cause rare allergic reactions, such as skin rash.

Instructions for use

The drug has the ability to quickly absorb and dissolve individual components throughout the blood and all internal organs. When taking a small dose of the drug, the most impressive amount of it is observed in the body after an hour, and in a large dosage - after an hour and a half. Arbidol is concentrated in the liver and is excreted within 24 - 26 hours through the kidneys or with bile.

Arbidol in capsules

The instructions for use of the product state that Arbidol is administered orally before the next meal. You need to take 800 mg for three days. This is the general picture of treatment.

Using the drug as a preventative measure has its own characteristics and nuances:

• If you find healthy person near the patient, the dosage should be about 2 tablets per day. At the same time, the course preventive treatment should be up to 14 days.
• For preventive measures to avoid recurrent bronchitis or the manifestation of herpes ulcers during an acute respiratory viral infection or influenza epidemic, take two tablets.
• Accept this drug recommended for complications of ARVI in close proximity to a sick person, 0.2 g. per day.
• To protect the weakened body in the postoperative period, it is also necessary to carry out prophylaxis in the amount of two tablets per day.

Arbidol for diseases

If any disease occurs, the medicine should be taken as follows:

• Mild form of influenza and acute viral respiratory infection. Patients need to take 800 mg per day every 6 hours for five days.
• Complicated forms of influenza and ARVI. In this case, patients must undergo the following course of treatment: take the standard dosage of 800 mg for 5 days, and then 2 tablets for a week.
• For the treatment of severe respiratory diseases, 400 mg of the drug per day for 10 days.
• For the treatment of chronic bronchitis or herpes, Arbidol is taken in combination with other drugs. It must be taken at 800 mg for a week, and then the dosage must be reduced to 4 tablets for a week.
• When sick with rotavirus, the complex is used. The drug is taken 800 mg per day for 5 days.

Allowed for children from 3 years old. The tablet must be thoroughly crushed into powder. The dosage of the drug varies not only between adults and children, but also between the children themselves. So it will be as follows:

• Children from 6 to 12 years old – 1 tablet per day.
• From 3 to 6 – half a tablet per day.

It will be the same for any reason for prophylactic use.

Dosage:

In uncomplicated forms of the disease of the upper respiratory tract children accept:

• For 3-6 years – half a tablet 4 times a day.
• For 6-12 years – 400 mg per day.

For diseases with complications, as well as the presence complex therapy when treating bronchitis or rotavirus, the dosage will be:

• From 3 to 6 years – 200 mg per day for a week. Then - 100 mg. within a week.
• From 6 to 12 years – 400 mg. per day for 7 days, then 200 mg for a week.

Children 12 years of age and older are treated the same as adults and take the same dosage as them.

Contraindications to the use of the drug for children

Arbidol for children should be taken with caution in those children who have the following types diseases:

• Hepatic or renal underdevelopment.
• Diseases of the cardiovascular system.
• Lactose intolerance.

Arbidol for children

Designed especially for children children's drug It has the following characteristic. His description completely matches that of an adult. In addition, children's Arbidol helps strengthen the immune system and also helps restore children's body after suffering from acute respiratory viral infection or acute respiratory infections. The drug should be taken half an hour before meals, washed down with water. It can also be combined with other drugs.

During pregnancy and lactation

Do not take during pregnancy This is due to the fact that the effect of such treatment is small, and the drug can have an effect on the fetus. However, in case of infection with virus A, Arbidol is absolutely necessary. In this case, you can use the minimum dosage.

During feeding, the product is strictly prohibited, since all its components can enter the baby’s body, causing complications.

Interaction with other drugs

No interactions with other drugs were found when taking the drug.

Domestic and foreign analogues

The following analogues of the drug are distinguished:

• Analogue of Arbidol - Amiksin. Available in tablets. Used to treat viruses groups A,B,C. , and also as a complex in the treatment of tuberculosis. Serves as a prophylactic agent in the treatment of acute respiratory infections and influenza.
• An analogue of the drug is Interferon. Drops intended for the treatment of the upper respiratory tract.
• An analogue of the product is Laferobion. Available in suppositories and helps cure viruses various groups, as well as in complex treatment of the sensory organs.
• An analogue of the drug is Viferon. Sold in the form of suppositories and used in the prevention of acute respiratory infections and acute respiratory viral infections.
• Analogue of Arbidol - Proteflazid. Available in the form of drops. For prevention viral diseases, as well as in the treatment of herpes.
• An analogue of the drug is Ferrovir. Available in the form of drops. Taken for the treatment of herpes, as well as in combination for patients with HIV infections and AIDS.
• An analogue of the drug is Detoxopirol. The drug is sold in tablet form. It is used for tonsillitis, laryngitis and otitis, bronchitis and influenza, acute respiratory infections and acute respiratory viral infections.
• An analogue of the drug is Armenicum. The drug is available in liquid form and is used for HIV infections.
• Arbidol's analogue is Engystol. Tablets used in the treatment of viral infections, skin diseases, and gynecological problems.
• An analogue of the drug - Coldact flu. It comes in the form of powder, capsules and suspensions. For colds.
• An analogue of the product is Immunal. Available in the form of drops and tablets. Helps improve Immunity.
• An analogue of the drug is Kagocel. Release form: tablets. Helps in modulating immunity.
• An analogue of the drug is Anaferon. Available in tablet form. Helps increase resistance to various types of infections.
• An analogue of the product is Theraflu. It is used in the form of powders for the treatment of acute respiratory infections and acute respiratory viral infections.
• Arbidol's analogue is Tamiflu. Available in the form of capsules and suspensions for the prevention and treatment of influenza.
• An analogue of the drug is Fervex. A powder that helps reduce fever and effectively treats colds.
• An analogue of the drug is Neoflu 750. For the treatment of ENT diseases, as well as for manifestations of influenza.
• Arbidol's analogue is Milife. Biologically active additive. Used for chronic fatigue, in combination with respiratory diseases. Suitable for people engaged in physical labor or undergoing physical activity.
• Mustard plaster package in a ribbon. Used for acute respiratory viral infections, acute respiratory infections and influenza. It can also be taken for bronchitis, pneumonia and osteochondrosis.