What is the difference between different types of almagel? Almagel - Instructions for use Almagel green packaging instructions for use

Almagel is an antacid drug.

Release form and composition

The drug Almagel is available in the form of tablets and suspensions intended for oral use.

Almagel suspension is presented in three forms: Almagel, Almagel A and Almagel Neo. In addition to the main components - aluminum oxide and magnesium oxide - two latest drugs contain respectively: benzocaine (painkiller) and simethicone (a substance that eliminates the cause of flatulence).

The classic Almagel suspension is white in color and has a lemon scent. During storage of Almagel, a layer of clear liquid is allowed to form, which disappears after vigorous shaking.

Below are the main active ingredients and their content in 5 ml of Almagel (1 teaspoon of medicine):

• 2. 18 g of aluminum hydroxide gel, which corresponds to 218 mg of aluminum oxide;
• 350 mg of magnesium hydroxide paste, which corresponds to 75 mg of magnesium oxide.

Almagel also contains additional ingredients:

• 10.9 mg methyl parahydroxybenzoate;
• 801.15 mg sorbitol;
• 1.635 mg lemon oil;
• 10.9 mg hyaetellose;
• 1.363 mg butyl parahydroxybenzoate;
• 98.1 mg 96% ethanol;
• less than 5 ml of purified water;
• 818 mcg sodium saccharinate dihydrate;
• 1.636 mg propyl parahydroxybenzoate.

The composition of suspensions type A and Neo differs from the above.

Almagel tablets are packaged in 24 or 12 pieces.

The suspensions are located in 170 ml bottles, together with a measuring spoon they are packaged in cardboard boxes. Each type of Almagel is located in a box of the corresponding color: classic - in green, Almagel Neo - in red, Almagel A - in yellow.

Indications for use of Almagel

According to the instructions for Almagel, the drug is effective in treating peptic ulcer duodenum or stomach in acute phases, gastritis in the acute or chronic phase, as well as with reflux esophagitis, duodenitis, diaphragmatic hernia and enteritis. It is recommended to take Almagel in case of gastrointestinal disorders caused by improper diets, intake medicines(primarily glucocorticosteroids and NSAIDs), as well as drinking alcoholic beverages and smoking.

Contraindications

Directions for use and dosage of Almagel

The drug is administered orally. Exact dosages prescribed by a doctor, the following are indicative.

Treatment of duodenal ulcer, as well as therapy of some types of gastric ulcer, is carried out by using Almagel between meals. Maintenance treatment consists of using the drug in an amount equal to 1 dosage spoon no more than 4 times a day. The duration of such therapy is up to 3 months.

As a preventive measure, Almagel should be taken 1-2 teaspoons.

The use of the drug by children is permitted only after consultation with a doctor. Children under 10 years of age should take 1/3 of the dose prescribed for adults. Children over 10 but under 15 years of age should take half the adult dosage.

It is recommended to begin treatment of diseases during which nausea, abdominal pain, and vomiting occur with the use of Almagel A; only after these symptoms have been eliminated do they switch to therapy with classic Almagel.

Side effects of Almagel

While taking the medicine, in rare cases, nausea, stomach cramps, vomiting, constipation, pain in the stomach, as well as changes in taste sensations may occur. As a rule, the above symptoms disappear after reducing the dose.

It is important to keep in mind that taking high doses of the drug may cause drowsiness.

Since long-term use of Almagel in high dosages in combination with eating food poor in phosphorus, it can provoke phosphorus deficiency, increased excretion and resorption of calcium in the urine; it is necessary to ensure adequate phosphorus intake from food during treatment with the drug. In addition, in patients with renal failure in chronic form Edema of the extremities, hypermagnesemia and dementia may occur. Rating: 5 - 1 vote

Almagel®, suspension for oral administration - polyethylene terephthalate bottle (bottle) 170 ml with a measuring spoon (scoop), cardboard pack 1 - EAN code: 3800009121082 - No. P N012742/01, 2010-02-26 from Balkanpharma-Troyan (Bulgaria)

Latin name

Almagel®

Active ingredient

Algeldrate* Magnesium hydroxide

ATX

A02AX Antacids in other combinations

Pharmacological group

Antacids in combinations

Nosological classification (ICD-10)

K21.0 Gastroesophageal reflux with esophagitisK25 Gastric ulcerK26 Duodenal ulcerK29 Gastritis and duodenitisK29.1 Other acute gastritisK29.5 Chronic gastritis, unspecifiedK44.9 Diaphragmatic hernia without obstruction or gangreneK52.9 Non-infectious gastroenteritis and colitis, unspecifiedY42.0 Unfavorable y reactions during the therapeutic use of glucocorticoids and their synthetic analoguesY45 Adverse reactions during the therapeutic use of analgesic, antipyretic and anti-inflammatory drugsZ72.4 Inappropriate diet and bad habits in nutrition

Composition and release form

5 ml of oral suspension contains aluminum hydroxide 300 mg (equivalent to 200 mg of aluminum oxide), magnesium hydroxide 100 mg - in plastic bottles of 170 ml complete with a dosing spoon, 1 bottle in a cardboard box.

Characteristic

A suspension of white or slightly grayish color with a characteristic sweetish taste and smell of lemon.

Pharmacological action

Pharmacological action - antacid, enveloping, adsorbing.

Neutralizes hydrochloric acid and reduces the activity of pepsin and gastric juice, protects the gastrointestinal mucosa from damaging effects.

Pharmacodynamics

It is evenly distributed throughout the gastric mucosa and provides long-lasting gastroprotection. It has buffering and antacid properties: between doses, the pH of gastric juice is maintained from 4-4.5 to 3.5-3.8. Sorbitol has a choleretic and mild laxative effect. The therapeutic effect appears after 3-5 minutes and lasts 70 minutes.

Pharmacokinetics

Practically not absorbed from the gastrointestinal tract.

Indications of the drug Almagel®

Peptic ulcer of the stomach and duodenum (acute phase), acute or chronic gastritis against the background of normal or increased secretion (exacerbation phase), reflux esophagitis, diaphragmatic hernia, duodenitis, enteritis, gastrointestinal disorders caused by poor diet, taking medications (NSAIDs, glucocorticoids), drinking coffee or alcohol, smoking.

Contraindications

Hypersensitivity, severe renal dysfunction, Alzheimer's disease, neonatal period, breastfeeding.

Use during pregnancy and breastfeeding

During pregnancy, use is possible for no longer than 3 days. Breastfeeding should be stopped during treatment.

Side effects

From the gastrointestinal tract: taste disturbance, nausea, vomiting, spasm, pain in the epigastric region, constipation.

Metabolism: hypercalciuria, hypermagnesemia, hypophosphatemia.

Other: drowsiness, osteomalacia, dementia and swelling of the extremities (due to chronic renal failure).

Interaction

Reduces the effectiveness of tetracyclines, H2-antihistamines, cardiac glycosides, iron salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indomethacin, ketoconazole, etc. (when administered together, an interval between doses of at least 1-2 hours is recommended).

Directions for use and doses

Orally, 0.5 hours before meals (for peptic ulcers of the stomach and duodenum between main meals) and at night, for adults, 1-3 dosage spoons 3-4 times a day. Maintenance dose - 1 dosage spoon 3-4 times a day for 2-3 months. Preventive therapy- 1-2 dosage spoons.

Children strictly as prescribed by the doctor: up to 10 years - 1/3 of the dose for adults, 10-15 years - 1/2 of the dose.

The maximum daily dose is 16 dosage spoons, with this dose the duration of treatment is no more than 2 weeks.

The suspension should be shaken before use.

In case of a disease accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of the listed symptoms, they switch to taking Almagel.

Overdose

Symptoms: depression of gastrointestinal motility.

Treatment: prescription of laxatives.

Precautions

At long-term use it is necessary to ensure sufficient intake of phosphorus from food.

Special instructions

At functional disorders accompanied by nausea, vomiting, and abdominal pain, treatment begins with Almagel A.

Storage conditions for the drug Almagel®

In a dry place, protected from light, at a temperature not exceeding 25 °C. Do not freeze!

Keep out of the reach of children.

Shelf life of the drug Almagel®

2 years.

Latest update of the description by the manufacturer

15.07.2008

Other packaging options for the drug are Almagel®.

Almagel®, suspension for oral administration - bottle (bottle) 170 ml with measuring spoon (scoop), cardboard pack 1 - EAN code: 3800009120016- No. P N012742/01, 2010-02-26 from Balkanpharma-Troyan (Bulgaria) Almagel® , suspension for oral administration - polyethylene terephthalate bottle (bottle) 170 ml with a measuring spoon (scoop), cardboard pack 1 - EAN code: 3800009121082 - No. P N012742/01, 2010-02-26 from Balkanpharma-Troyan (Bulgaria)

Almagel A (aluminum hydroxide + magnesium hydroxide + benzocaine) is an antacid drug, “enhanced” by the addition of an anesthetic. The drug neutralizes free hydrochloric acid in the stomach, which reduces the digestive ability of gastric juice. The drug does not cause the so-called “acid rebound” - the development of secondary gastric hypersecretion. Has a local anesthetic, enveloping and adsorbing effect, neutralizes the influence of aggressive factors on the mucous membrane gastrointestinal tract. The drug begins to act within 3-5 minutes from the moment of administration and provides a lasting and pronounced therapeutic effect for 70 minutes. During this entire time, Almagel A ensures stable neutralization of constantly produced gastric juice and reduces the concentration of hydrochloric acid in it to the required limits. Aluminum hydroxide (alhedrate) inhibits the secretion of pepsin, neutralizes hydrochloric acid with the formation of aluminum chloride, which, in turn, entering the intestines and swallowing the local alkaline “spirit of freedom”, turns into an alkaline salt. Magnesium hydroxide also neutralizes hydrochloric acid, forming magnesium chloride. The antagonistic attitude of magnesium hydroxide in relation to the tendency of aluminum hydroxide to cause constipation ensures the uninterrupted functioning of the physiological “conveyor” digestive tract. The third in line, but not least important, component of Almagel A - benzocaine - has a long-lasting and pronounced local anesthetic effect. Sorbitol included in the drug as an excipient facilitates bile excretion and exhibits a mild laxative effect, harmoniously complementing the action of magnesium hydroxide. Almagel A smoothly but confidently shifts the pH to the “alkaline” side, “anchoring” it within physiological limits from 3.5 to 4.5. The drug forms a protective shell, ensuring uniform distribution of active substances on the gastric mucosa, and has a long-lasting local effect without formation in the stomach carbon dioxide, which, in turn, causes flatulence, discomfort in the epigastric region and secondary hypersecretion of hydrochloric acid.

Almagel neo is practically non-toxic: it does not have teratogenic or mutagenic effects. In isolated cases in newborns whose mothers long time took the drug, an increase in tendon reflexes was observed. In addition, in newborns there is a risk of a pathological increase in the amount of magnesium in the blood plasma, especially in a state of dehydration, and therefore long-term use of the drug for pregnant women and newborns is not recommended.

Almagel A is practically not absorbed from the gastrointestinal tract. The drug does not disturb the water-salt balance and does not create any prerequisites for the occurrence of alkalosis and other metabolic disorders. Almagel A does not have an irritating effect on the urogenital tract and does not contribute to the formation of stones even with a long course of medication. Available in the form of a suspension for oral administration. A measuring spoon is included in the package with the drug to ensure dosing accuracy. A single dose for adults is 1-3 scoops (their quantity is determined by the severity of clinical case). Frequency of administration: 3-4 times a day, 30 minutes before meals and before bedtime. The maximum daily dose is 16 spoons. In children, the drug is used exclusively as prescribed by a doctor and under medical supervision: children under 10 years old take a third of the “adult” dose, children from 10 to 15 years old take half. For diseases that are clinically manifested by nausea, vomiting and abdominal pain, pharmacotherapy begins with Almagel A, then the patient is transferred to Almagel. The bottle of the drug must be shaken before use. It is not recommended to take any other medications 1-2 hours before taking Almagel A and the same time after it.

Pharmacology

The instructions were approved by the Pharmacological Committee of the Russian Ministry of Health on March 2, 2001.

Almagel A neutralizes free hydrochloric acid in the stomach, which leads to a decrease in the digestive activity of gastric juice. Does not cause secondary hypersecretion of gastric juice. Provides local anesthetic, adsorbent and enveloping effect, reduces the influence of damaging factors on the mucous membrane.

The therapeutic effect after taking the drug occurs within 3-5 minutes and lasts an average of 70 minutes.

Almagel A provides long-term local neutralization of continuously secreted gastric juice and reduces the content of hydrochloric acid in it to optimal limits for treatment. Aluminum hydroxide suppresses the secretion of pepsin, neutralizes hydrochloric acid, forming aluminum chloride, which in the alkaline environment of the intestine turns into alkaline aluminum salts. Magnesium hydroxide also neutralizes hydrochloric acid, turning into magnesium chloride. This counteracts the constipating effects of aluminum hydroxide. Magnesium hydroxide and magnesium chloride are resorbed into minor degree and have virtually no effect on the concentration of magnesium ions in the blood.

Benzocaine has an effective and long-lasting local analgesic effect in severe pain.

Sorbitol, which is part of the drug, promotes increased secretion of bile and exhibits a mild laxative effect, complementing the effect of magnesium hydroxide.

Almagel A does not sharply increase the pH of the stomach contents; it buffers its value from 4.0–4.5 to 3.5–3.8 ( physiological significance) in the period between doses. The drug forms a protective layer, ensuring uniform distribution on the gastric mucosa active substances and has a long lasting local action without the subsequent formation of carbon dioxide in the stomach, which, in turn, causes flatulence, a feeling of heaviness in the epigastric region and a secondary increase in the secretion of hydrochloric acid.

According to the Hodge and Sterner classification, the drug oral administration It is a mildly toxic drug and does not have embryotoxic, teratogenic or mutagenic effects. In some cases, increased tendon reflexes were noted in newborns whose mothers took the drug for a long time. In addition, in newborns there is a risk of developing hypermagnesemia, especially in a state of dehydration, therefore long-term use of the drug for pregnant women and newborns is not recommended.

Pharmacokinetics

Almagel A is a non-absorbable drug. Subject to correct mode dosage and duration of treatment, it is practically not resorbed in the gastrointestinal tract and has a long-lasting, uniform effect without disturbing the electrolyte balance and without creating the risk of alkalosis or other metabolic disorders. It does not irritate the urinary system and long-term use does not cause alkalosis and the formation of stones in the urinary tract.

Release form

Oral suspension white or almost white, with a characteristic lemon smell; During storage, a layer of transparent liquid may form on the surface; vigorously shaking the bottle will restore the homogeneity of the suspension.

Excipients: sorbitol - 801.15 mg, hyaetellose - 15.26 mg, methyl parahydroxybenzoate - 10.9 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 0.818 mg, lemon oil - 1.635 mg, ethanol 96% - 98. 1 mg, purified water - up to 5 ml.

170 ml - bottles (1) complete with a dosing spoon - cardboard packs.

Dosage

Inside. As prescribed by a doctor, 1-3 dosage (teaspoons) depending on the severity of the case, 3-4 times a day half an hour before meals and in the evening before bed.

For diseases accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of the listed symptoms, they switch to taking Almagel.

The bottle should be shaken before use.

Interaction

With simultaneous use, Almagel A can reduce the therapeutic effect of tetracycline antibiotics, histamine H2 receptor blockers, digitalis glycosides, iron salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indomethacin and ketokenozol, etc.

Side effects

In some cases, when taking the drug, changes in taste sensations, nausea, vomiting, stomach cramps, pain in the epigastric region and constipation may occur, which disappear after reducing the dose. May cause drowsiness when used in high doses.
Long-term treatment with high doses of the drug and phosphorus-poor food can lead in predisposed patients to the development of phosphorus deficiency in the body, increased resorption and excretion of calcium in the urine and the occurrence of osteomalacia. Therefore, when taking the drug for a long time, it is necessary to ensure a sufficient intake of phosphorus from food.
In patients with chronic renal failure In addition to osteomalacia, swelling of the extremities, dementia and hypermagnesemia may be observed.

Indications

• peptic ulcer of the stomach and duodenum in the acute phase;
• acute gastritis and chronic gastritis with increased and normal secretory function in the acute phase;
• duodenitis;
• enteritis;
• hernia hiatus diaphragms;
• reflux esophagitis;
• functional bowel disorders, colitis;
• discomfort and pain in the epigastrium due to errors in diet, after drinking coffee, nicotine, alcohol;
• prophylactically in the treatment of GCS and NSAIDs.

In the complex therapeutic measures Almagel A is prescribed to patients with diabetes.

Contraindications

• hypersensitivity to the components of the drug;
• pronounced violation kidney function;
• Alzheimer's disease;
• early childhood(up to 1 month).

Do not prescribe simultaneously with sulfonamides due to the presence of benzocaine in the drug.

Features of application

Use during pregnancy and breastfeeding

Avoid administration to nursing mothers.

Use for renal impairment

Contraindicated: severe renal impairment.

Use in children

Contraindicated: early childhood (up to 1 month).

In children, the drug is used strictly as prescribed by a doctor: children under 10 years of age are prescribed 1/3 of the dose for adults, and children from 10 to 15 years of age are prescribed 1/2 of the dose for adults.

Special instructions

Interval between taking Almagel A and others medicines should be 1-2 hours.

When taking the drug for a long time, you should ensure a sufficient intake of phosphorus from food.

INSTRUCTIONS
on the use of a medicinal product for medical use

REGISTRATION NUMBER: P N012742/01-160512

TRADE NAME OF THE DRUG: ALMAGEL ®

INTERNATIONAL NON-PROPENTED OR GROUP NAME:
Algeldrate+Magnesium hydroxide

DOSAGE FORM: Oral suspension

COMPOUND
1 measuring spoon (5 ml) of suspension contains:

Active substances:
Algeldrate (aluminum hydroxide gel 2.18 g, corresponding to 218 mg of aluminum oxide), magnesium hydroxide paste 350 mg, corresponding to 75 mg of magnesium oxide); Excipients: sorbitol 801.150 mg, hyaetellose 10.900 mg, methyl parahydroxybenzoate 10.900 mg, propyl parahydroxybenzoate 1.363 mg, butyl parahydroxybenzoate 1.363 mg, sodium saccharinate dihydrate 0.818 mg, lemon oil 1.635 mg, ethanol 96% 98.100 mg , purified water up to 5 ml.

DESCRIPTION
A suspension of white or almost white color with a characteristic lemon odor. During storage, a layer of clear liquid may form on the surface. By vigorously shaking the contents of the bottle, the homogeneity of the suspension is restored.

PHARMACOTHERAPEUTIC GROUP
Antacid.
ATX code: A02AX

PHARMACOLOGICAL ACTION

Pharmacodynamics
Almagel is a medicine that is a balanced combination of algeldrate (aluminum hydroxide) and magnesium hydroxide. It neutralizes free hydrochloric acid in the stomach, reduces the activity of pepsin, which leads to a decrease in the digestive activity of gastric juice. Has an enveloping, adsorbing effect. Protects the gastric mucosa by stimulating the synthesis of prostaglandins (cytoprotective effect).
This protects the mucous membrane from inflammatory and erosive-hemorrhagic lesions as a result of the use of irritating and ulcerogenic agents, such as ethanol and non-steroidal anti-inflammatory drugs (for example, indomethacin, diclofenac, aspirin, acetylsalicylic acid, corticosteroid drugs). The therapeutic effect after taking the drug occurs within 3-5 minutes. The duration of action depends on the rate of gastric emptying. When taken on an empty stomach, the effect lasts up to 60 minutes. When taken one hour after a meal, the antacid effect can last up to 3 hours.

Does not cause secondary hypersecretion of gastric juice.

Pharmacokinetics
Algeldrat
Suction- small amounts of the drug are resorbed, which practically do not change the concentration of aluminum salts in the blood.
Distribution- No.
Metabolism- No.
Removal- excreted through the intestines.

Magnesium hydroxide
Suction- magnesium ions are resorbed in about 10% of the dose taken and do not change the concentration of magnesium ions in the blood.
Distribution- usually locally.
Metabolism- No.
Removal- excreted through the intestines.

INDICATIONS FOR USE
Treatment

• Acute gastritis; chronic gastritis with increased and normal secretory function of the stomach (in the acute phase); acute duodenitis, enteritis, colitis;
• peptic ulcer of the stomach and duodenum (in the acute phase);
• hiatal hernia, gastroesophageal reflux, reflux esophagitis, duodenogastric reflux;
• symptomatic gastrointestinal ulcers of various origins; mucosal erosion upper sections gastrointestinal tract;
• acute pancreatitis, exacerbation of chronic pancreatitis;
• heartburn and epigastric pain after errors in diet, excessive consumption of ethanol, nicotine, coffee, taking medications that irritate the gastric mucosa.

Prevention gastric and duodenal disorders - reducing the irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.

CONTRAINDICATIONS

• Hypersensitivity to the drug or to any excipient, which is part of the drug.
• Severe form of renal failure (due to the risk of developing hypermagnesemia and aluminum intoxication).
• Pregnancy.
• Alzheimer's disease.
• Hypophosphatemia.
• Children's age up to 10 years.
• Congenital fructose intolerance (contains sorbitol).

Use during pregnancy and lactation
Animal studies have shown that there is no evidence of teratogenic potential or other unwanted effects to the embryo and/or fetus.

There are no clinical data on the use of Almagel by pregnant women. The drug is not recommended during pregnancy, but if the expected benefit from its use outweighs the potential risk to the fetus, the drug should be taken under medical supervision for no more than 5-6 days.

There is no data on the release of the active substances of the drug from breast milk. Almagel can be used during breastfeeding only after a careful assessment of the balance of benefits for the mother and potential risk for a newborn. During breastfeeding, it is recommended to use no more than 5-6 days under medical supervision.

METHOD OF APPLICATION AND DOSES

Treatment

Adults and children over 15 years old
5-10 ml (1-2 measuring spoons) 3-4 times a day. If necessary, the single dose can be increased to 15 ml (3 scoops).

Children from 10 to 15 years old
Used in a dose equal to half the dose for adults.
The drug is taken 45-60 minutes after meals and in the evening before bedtime.
After reaching therapeutic effect daily dose reduce to 5 ml (1 measuring spoon) 3-4 times a day for 15-20 days.
It is not recommended to take liquids within 15 minutes after taking Almagel.
Before each dose, the suspension must be thoroughly homogenized by shaking the bottle!

For prevention
5-15 ml 15 minutes before taking medications with irritating effects.

SIDE EFFECTS
Almagel can cause constipation, which goes away after reducing the dose. In rare cases, nausea, vomiting, stomach spasms, changes in taste sensations, allergic reactions and hypermagnesemia (increased magnesium levels in the blood). With prolonged use of the drug by patients with renal failure and on dialysis, changes in mood and mental activity are possible. With long-term use of high doses of the drug, along with a deficiency of phosphorus in food, osteomalacia may occur.

OVERDOSE
If the dose is exceeded once, no other signs of overdose are observed except constipation, flatulence, and a metallic taste in the mouth.

With prolonged use of high doses, the formation of kidney stones, severe constipation, mild drowsiness, and hypermagnesemia are possible. There may also be signs metabolic alkalosis: changes in mood or mental activity, numbness or muscle pain, irritability and fatigue, slow breathing, unpleasant taste.

In these cases, it is necessary to immediately take measures to quickly remove the drug from the body - gastric lavage, inducing vomiting, taking activated charcoal.

INTERACTION WITH OTHER MEDICINES
May absorb some medications, thereby reducing their absorption, so if simultaneous administration other medications, they must be taken 1-2 hours before or after taking Almagel.

Almagel reduces the acidity of gastric juice, and this can affect the effect of a large number of medications when taken simultaneously.

Almagel reduces the effect of histamine H2 receptor blockers (cimetidine, ranitidine, famotidine), cardiac glycosides, iron salts, lithium preparations, quinidine, mexiletine, phenothiazine drugs, tetracycline antibiotics, ciprofloxacin, isoniazid and ketoconazole.

When taking enteric drugs simultaneously, the increased pH of gastric juice can lead to accelerated breakdown of their membranes and cause irritation of the stomach and duodenum.

Almagel may affect the results of some laboratory and functional studies and tests: it reduces the level of gastric secretion when determining its acidity; alters test results using technetium (TC99), such as bone scintigraphy and some esophageal tests, increases serum phosphorus levels, serum and urine pH values.

SPECIAL INSTRUCTIONS
The use of the drug in patients with severe constipation is not recommended; for stomach pain of unknown origin and suspected acute appendicitis; if available ulcerative colitis, diverticulosis, colostomy or ileostomy; at chronic diarrhea; acute hemorrhoids; when the acid-base balance in the body changes, as well as in the presence of metabolic alkalosis; with cirrhosis of the liver; severe heart failure; with toxicosis of pregnant women; with impaired renal function (creatinine clearance) With prolonged use of the drug (more than 20 days), regular medical monitoring of serum magnesium levels is necessary when treating patients with renal failure.

The drug does not contain sugar, which allows it to be taken by patients diabetes mellitus. The drug contains sorbitol, which is contraindicated in cases of congenital fructose intolerance.

Impact on the ability to drive a car and operate machinery
Almagel does not affect the ability to drive a car or operate machinery. When taken in the recommended daily dose, the ethyl alcohol contained in the drug does not affect the ability to drive a car or operate machinery.

RELEASE FORM
Suspension for oral administration.
170 ml of the drug in a dark glass bottle with a screw-on plastic cap. Each bottle along with instructions for use and a 5 ml measuring spoon in a cardboard box.
170 ml of the drug in a polyethylene terephthalate bottle with a screw-on plastic cap. Each bottle along with instructions for use and a 5 ml measuring spoon in a cardboard box.

STORAGE CONDITIONS
In a place protected from light, at a temperature not exceeding 25°C.
Do not freeze!
Keep out of the reach of children!

BEST BEFORE DATE
2 years.
Do not use after the expiration date indicated on the package!

CONDITIONS OF VACATION FROM PHARMACIES
Over the counter.

MANUFACTURER
Balkanfarma-Troyan AD, Bulgaria
5600, Troyan, st. "Krayrechna" No. 1

Consumer complaints should be sent to:
Actavis LLC
127018, Moscow, st. Sushchevsky Val, 18

Almagel is the first antacid drug. Antacids are intended for the treatment of acid-related diseases of the gastrointestinal tract by neutralizing the hydrochloric acid contained in gastric juice.

The active component of Almagel - aluminum hydroxide - has become the basis for the production of a number of antacid drugs.

In this article we will look at why doctors prescribe Almagel, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS People who have already used Almagel can be read in the comments.

Composition and release form

Depending on the composition there are the following types suspensions:

• Almagel - contains only the main components (aluminum and magnesium hydroxide);
• Almagel A - along with active active ingredients contains benzocaine (pain reliever);
• Almagel Neo - contains an additional component, simethicone, which eliminates gases.

Clinical and pharmacological group: antacid drug.

What does Almagel help with?

As a rule, Almagel is used for the following diseases associated with increased acidity:

1. Flatulence;
2. Esophagitis;
3. Enteritis, duodenitis;
4. Foodborne toxic infections;
5. Hernia;
6. Gastritis is acute with high acidity;
7. Stomach ulcer, exacerbation of duodenal ulcer;
8. Pain, discomfort arising in the gastric region due to diet violations, abuse alcoholic drinks, nicotine, coffee, and medications.

The drug is also used in for preventive purposes as a prevention of the development of ulcerative lesions when using anti-inflammatory non-steroidal substances and glucocorticosteroids.

Pharmacological action

Almagel is an antacid drug. Its action is based on local long-term neutralization of constantly formed gastric juice. According to the instructions, Almagel reduces the content of hydrochloric acid in gastric juice to the optimal level. The product has a local anesthetic effect.

The drug produces a slight laxative effect, is choleretic agent. Aluminum hydroxide, which is part of Almagel as one of active ingredients, inhibits the secretion of pepsin. Coming into contact with hydrochloric acid, it neutralizes it by forming aluminum chloride.

Efficiency this drug is also due to its specific gel-based consistency, which allows Almagel to be evenly distributed throughout the gastric mucosa, thereby providing a longer-lasting effect. The effect of taking the drug begins 3-5 minutes after a single dose, and its duration is approximately 70 minutes.

Instructions for use

According to the instructions for use, each time before use the bottle of Almagel must be shaken thoroughly.

• Adults and children over 15 years of age are prescribed 5-10 ml (1-2 scoops) 3-4 times a day. If necessary, the single dose can be increased to 15 ml (3 scoops). Children aged 10 to 15 years are prescribed at a dose equal to half the dose for adults. After achieving a therapeutic effect, the daily dose is reduced to 5 ml (1 scoop) 3-4 times a day for 15-20 days.
• For prevention, it is recommended to take 5-15 ml 15 minutes before taking medications with irritating effects.

Contraindications

Side effects

After taking all types of Almagel, the following side effects may be observed:

1. Nausea, vomiting.
2. Stomach cramps.
3. Distortion of taste sensations.
4. Pain in the epigastric region.
5. Constipation.
6. Drowsiness.

Maximum doses of the drug in combination with a lack of phosphorus intake from food causes manifestations of phosphorus deficiency, increased excretion of calcium in the urine and the development of osteomalacia.

Pregnancy and lactation

There are no clinical data on the use of Almagel in pregnant women and during breastfeeding. The drug is not recommended for use in this case, but if the expected benefit to the mother outweighs the potential risk to the fetus, Almagel should be used under medical supervision for no more than 5-6 days.

Experimental studies in animals have shown no teratogenic potential or other undesirable effects on the embryo and/or fetus.

Almagel analogues

The following are drugs whose composition and mechanism of action are similar to Almagel:

1. Gastal;
2. Rennie;
3. Inalan;
4. Gastroromazole.

Attention: the use of analogues must be agreed with the attending physician.

Prices

The average price of ALMAGEL in pharmacies (Moscow) is 195 rubles.