Find analogues of medicines. Russian analogues of imported drugs: an adequate replacement? Anti-inflammatory and antipyretic

Very often, prescribed drugs from well-promoted imported pharmaceutical companies are expensive, so patients, in search of a more economical option, look for analogues of the drugs prescribed to them, quite often these are medicines for colds and flu, probiotics or vitamins and microelements. They also often look for analogues of medications widely advertised on TV, antihistamines, nootropics and what advertising calls “cure for VSD.”

In this case, it is better to choose complete analogues or generics, that is, drugs that also contain the same amount of active ingredient. For example, we are looking for analogues and find a product such as Aspartame, the price of which is an order of magnitude lower than Panangin. If such a remedy cannot be found, with the consent of the attending physician, you can pay attention to substances that are similar in their effect, but contain another active substance.

Since they are usually looking for not just analogs of drugs - cheap analogues of expensive drugs, it is unlikely that it would be beneficial for pharmacy workers to recommend such a replacement. Therefore, those who need such a replacement should refer to our article, and also expand their knowledge by reading Medical reference medicines and their analogues. We will not be able to talk about all medications and their analogues within the framework of this article - full list this is a multi-volume work. Therefore, we will focus on those that today often appear in commercials and those that patients are most interested in.

Scene in a pharmacy (cheap analogues of expensive drugs)

Examples of analogues of drugs from different groups

Most often, when receiving a doctor's prescription, we buy the wrong thing at the pharmacy. cheap drug. It is not the topic of the article to analyze the reasons for this situation; let’s just say that analogues of drugs in the Russian Federation cost two times, and sometimes an order of magnitude less, than imported analogues. Most often, the effect is satisfactory, and the cost savings are obvious.

However, buying cheap analogue, it is not always possible to achieve the desired effect. That is, by buying a more expensive product, we get the result promised by the instructions. And when purchasing a cheap option, we get a much weaker effect, although the active substance and its concentration are identical expensive product. At least this follows from patient reviews.

The reason for this phenomenon can only be explained by conducting appropriate research. Perhaps in some cases the situation can be explained psychological factor(trust in foreign pharmacological companies is higher), in others the drug is counterfeit. Perhaps there are other reasons.

Probiotics

Considering the frequency of use of antibiotics to treat certain bacterial infections in humans, animals, and their treatment of plants, it can be argued that the intestinal microflora is exposed to substances that are harmful to it quite intensively. It’s not surprising that you have to take probiotics Linex, Symbiolact or eubiotics Enterol and Bioflor.

These are high-quality probiotics that contain not only bifidobacteria and lactobacilli, but also enterococci (Symbiolact). Eubiotics may contain either Saccharomycetes (Enterol), Escherichia coli (Bioflor) and other preparations that contain certain microorganisms needed by the intestines.

Accordingly, the price of these drugs is not the lowest. Linex costs from 250 rubles. It is not surprising that patients are looking for analogs with more reasonable price. Unfortunately, there are no cheap complete analogues for this product. The most acceptable analogues of tablets are:

• Lactobacterin - from 113 rubles;
• Gastrofarm from 75 rubles.

Other drugs are comparable in price to Linex or more expensive.

Antihistamines

They are usually called allergy medications. Today, there are first-generation antihistamines (Diazodin, Diphenhydramine) and second-third generation (Claridon, Rupafin, Trexil, Telfast).

First generation antihistamines suffers from serious side effects, the main of which is increased drowsiness. This significantly reduces the performance of an allergy sufferer; it is especially difficult to take them for those whose work involves risk (drivers, construction equipment operators and others), and Diphenhydramine is also addictive.

Representatives of the next two generations are deprived of this disadvantage. But the cost leaves much to be desired. It is difficult to find complete analogues of cheap drugs for this group of drugs - analogues of expensive drugs, as a rule, are not complete and belong to the first generation drugs.

For those who are looking for cheap analogues of medicine, we can recommend looking at the price table for analogues of expensive medicines:

You can also find analogues at a cheaper price. For example, Chloropyramine tablets cost about 64 rubles. Second- and third-generation drugs cost from 200 rubles, for example Claritin costs about 204 rubles.

"Anti-cold" remedies

Most often, when a pharmacy asks for a medicine for flu and colds, they mean drugs that reduce the symptoms of a viral infection (cough, runny nose, sore throat, fever). That is, medications that contain antipyretic and non-steroidal anti-inflammatory components, and sometimes vitamin C and an antihistamine. But this category also includes antivirals, as well as immunomodulators and immunostimulants.

A striking and advertised example of such a “cold cure” is Theraflu. This product is worth it quick help for colds and flu - about 338 rubles. Is it possible to find something cheaper? Of course, see analogues of medications, table of “anti-cold powders”:

You can replace this drug with such incomplete analogues of drugs as Antiflu at a price of 113 rubles or Coldrex at 116 rubles. They differ slightly in composition from Theraflu, but give approximately the same effect. Choosing cheap analogues of drugs, in case colds, you should know that in most cases it is enough to take a banal one at a price of 16 rubles and ascorbic acid 15 rubles per package.

If the disease is viral in nature, you cannot rely on antipyretic and anti-inflammatory drugs; they only eliminate the symptoms, but do not prevent the virus from developing. This role is performed antiviral drugs, for example Rimantadine, Kagocel and others. Kagocel costs about 220 rubles and has no analogues. One of the cheapest is Rimantadine. Rimantadine is an analogue for Kagocel and costs 50 rubles. But we classified it as analogues only conditionally.

Vitamin preparations and microelements

This large group funds that pharmaceutical companies packaged in beautiful boxes and given intriguing names, and all this is quite affordable high price. Although there are products that have the same effect at a much lower price. Most often, for such drugs, patients look for cheap analogues of drugs:

• Neurobion;
• Aginovit and others.

The list of cheap analogues of expensive drugs will be as follows: there is a Russian analogue for Multigamma. An analogue of Iodomarin (124 rubles) is Potassium Iodide (94 rubles). Neurobion, which costs about 340 rubles, can be successfully replaced at a price of 230 rubles.

Antihypertensives and drugs that improve heart function

If in our young years we do not notice how our “engine” works. With age, the heart, an organ that does not know sleep and rest, begins to malfunction, tachycardia and arrhythmia appear, and blood pressure rises. To help this important body there are many remedies. For example, we provide a table with prices for medications and their analogues:

Drug name	Price/rubles	Analog/Substitute	Price/rubles
Panangin	122	Asparkam	33
Eltacin	170	No
Nebilet	500	Nebivolol	157
	115	(not analogue)	5

Panangin is an original drug from the Gideon Richter company, produced in the form of dragees, the shell of which makes it easy to swallow. For Panagin, the analogue is . It is in tablet form and is less comfortable to swallow. In addition, the drugs differ only in manufacturer and price.

Advertising positions Eltacin as a remedy for VSD, almost the only and absolute one. This is not entirely true. This is a metabolite drug. It is designed to normalize metabolic processes in the heart muscle and reduce tissue hypoxia. It's an antioxidant. Its main purpose is to help the myocardium in chronic heart failure; to combat the syndrome of vegetative-vascular dysfunction it is prescribed to children aged 12 to 18 years as part of complex therapy. It contains amino acids:

• Glycine;
• Cystine;
• Glutamic acid.

For Eltacin, many sites call the analogue of this medicine Glycine (46 rubles). As can be seen from the composition of the drug, Glycine is only its constituent component. Eltacin costs about 170 rubles. There is no complete analogue to this remedy.

Nibilet is a third-generation cardioselective beta-blocker with vasodilator properties. This means that the drug reduces the need for oxygen in the heart muscle and has antiarrhythmic effect and with its help you can achieve a lasting hypotensive effect. It costs about 500 rubles. Replacing the medicine with cheaper analogues is possible.

For the drug Nebilet, analogues of this medicine are produced in Crovania (Binelol at 382 rubles for 14 tablets), and India (Nebivator for 370 rubles for 14 tablets), and Russia (Nevibol, Kanofarm for 286 rubles for 24 tablets).

Cheap analogues and generics of popular drugs

It is difficult to present cheap analogues of expensive drugs with a complete list for 2016, but we have nevertheless selected a fairly wide list.

It’s easier to look at cheap drug analogues in tables. They are recorded in tables using a variety of principles. Sometimes they are grouped according to the pathologies for which they are used. Sometimes by drug groups, in some cases by the frequency of requests. In some cases, identifying a classification criterion is very difficult. We offer several table options that can be used when selecting drug analogues.

Video: Expensive drugs and their cheaper analogues

The domestic pharmaceutical market offers a wide variety of drugs, but at the same time, most of them are very expensive. As an affordable alternative, many people prefer to choose Russian analogues of imported drugs, the list and compliance of which can be obtained from the attending physician or pharmacist at the pharmacy.

Painkillers and antispasmodics

Painkillers (analgesics) are intended to relieve pain syndromes of various origins. In general, analgesics are divided into 2 groups:

• Non-narcotic drugs containing acetylsalicylic acid, analgin, paracetamol, mefinamic acid, piroxicam, ibuprofen, dimexide, etc.
• Narcotic drugs that are prescribed in the most extreme and serious cases, for example, morphine, promedol, fentanyl, etc.

Antispasmodic drugs (antispasmodics, antispasmodics) are intended to relieve spasms of blood vessels and smooth muscles internal organs, for example, the gastrointestinal tract, urinary and biliary tract, female reproductive system.

Cardiac and hypotensive

Cardiac drugs combine several groups of drugs to improve ischemic and cerebral circulation, normalization heart rate, increasing the content and transport of oxygen to the heart.

Antihypertensive (antihypertensive) medications are intended to lower blood pressure. The required effect can be achieved by different principles actions of drugs:

• decreased tone of the sympathetic nervous system;
• suppression of renin production (a component of the blood pressure regulation system);
• vasodilation;
• increasing urine output (diuretics).

Antibacterial and antiviral

Antibacterial drugs (antibiotics) are drugs that inhibit the growth of harmful microorganisms or cause their death.

Antivirals are medications that are used to treat viral diseases of various origins. They are often used to prevent viral diseases and to increase the body’s immunity in complex therapy.

Anti-inflammatory and antipyretic

Nonsteroidal anti-inflammatory drugs (NSAIDs, NSAIDs) have an anti-inflammatory effect, to which antipyretic and analgesic effects are also added.

Antidiarrheal

Diarrhea (stomach upset) is common symptom various diseases Gastrointestinal tract, other internal organs, intoxications. Antidiarrheal drugs reduce intestinal motility, increase sphincter tone. This group also includes eubiotics (enzymes and bacteria that regulate the microflora of the gastrointestinal tract) and adsorbents (cleaning the gastrointestinal tract from toxins and allergens).

Name	Active ingredient	Russian analogue
Imodium	Loperamide	Vero-Loperamide Diara Loperamide
Linux	Lactic acid and bifidobacteria	Bifidumbacterin Bifinorm Lactobacterin Lactonorm
Nifuroxazide	Nifuroxazide	Ecofuril
Smecta	Dioctahedral smectite	Diosmectite Neosmectin
Sorbex	Activated carbon	Activated carbon

Antiulcer

The action of antiulcer drugs is aimed at eliminating ulcerative manifestations on the gastric mucosa and duodenum. They reduce excessive secretion of gastric secretions, reduce the activity of pepsin (the main enzyme gastric juice), destroy Helicobacter in the gastrointestinal tract, normalize motility upper sections digestive tract.

Antiallergic

Anti-allergy medications (antihistamines) block histamine receptors in the body, a neurotransmitter that affects the respiratory tract, skin, gastrointestinal tract, blood vessels, smooth muscles and causes symptoms allergic reaction.

Inhalation drugs and cough suppressants

Inhalation is a method of introducing drugs into the body by inhaling steam, gas or smoke. To carry it out, nebulizer devices (inhalers, nebulizers) are used, which are filled with gaseous, liquid or volatile substances.

Mucolytic agents are cough medications that discharge mucus in the lungs and facilitate its elimination, reducing inflammation in the respiratory tract.

Calming

Sedatives (sedatives, psycholeptics) are a group of medications that cause calm or reduce emotional stress without a hypnotic effect, and at the same time facilitate the process of falling asleep and improve the quality of sleep.

Preparations for external use

The group of medicines for external (local) use combines a huge number of drugs in the form of ointments, gels, creams, solutions, powders, etc. Depending on the composition, they have antibacterial, disinfectant, analgesic, anti-inflammatory, antihistamine and other effects.

They cost several times, you need to understand the system for creating and selling medicines. The first to appear on the pharmaceutical market original drugs. The factory spends a huge amount of money on developing the drug and eventually receives a patent for production and distribution. As a rule, the validity period of a patent is 10 years. During this time, no one has the right to create medicines.

Upon expiration of the patent medicine becomes available to everyone. It is from this moment that the creation of analogues begins.

Thus, it turns out that the original drug costs many times more because it has been tested by people for 10 years. In addition to the costs of developing the drug, huge amounts of money were also spent on refining and improving it.

What are the differences between cheap analogues of expensive drugs?

Firstly, it is worth noting that not all analogues have a completely identical composition to the original. Most often, only the active substance is identical. But in addition to it, the medicine also contains additional elements responsible for the delivery of the substance, its absorption into the body and activation. But it is thanks to additional substances that some drugs act as quickly as possible.

Typically, large pharmaceutical companies care about high quality raw materials. It also takes a lot of money to process and clean it. Cheap analogues very often contain substances that do not best quality, brought from India and Eastern Europe.

You can also notice that using the original, the patient gets back on his feet in a matter of days, but there is no effect from taking generics. And although, at first glance, the compositions of these two drugs are the same, the effect is different. This is because research was carried out on the originals for 10 years under exclusive rights. There may simply be a tiny difference in composition that cannot be calculated or standardized, as a result of which the effectiveness of the original has become much higher.

What to take? Original or analogue

First of all, you need to look at the severity of the disease. If a person’s life depends on a medicine, then there is no point in experimenting. It is better to take a time-tested drug. If the disease is not critical, then you can try taking an analogue. There is a possibility that the generic will have a similar effect on the body as the original, and will cost an order of magnitude less.

It is important to remember which analogues did not work before. Most likely, if you purchase them again, they will also not give any effect.

Best articles
2015

They say there are no simple times. But how little consolation this is when you are faced with a total rise in price for everything! The basis of today's home economy is saving. We constantly have to look for “something similar, but cheaper.” Are such replacements correct and how can you avoid oxygen deficiency when trying to tighten your belts?

"Disservice" of the Internet

The most popular and almost bottomless storehouse of information is, of course, the Internet. We fearlessly plunge into the World Wide Web, naively believing that the mind will help distinguish lies from truth. But, alas, this is not always the case.

Millions Russian citizens in an effort to save money, they study the lists that fill the Internet domestic analogues expensive imported medicines. Tomorrow they will go to the pharmacy and with undisguised pleasure will buy a cheap domestic “substitute” instead of the original drug. And then the story can have a different continuation, and it depends on the anonymous person with an unknown education who posted the information, and on His Majesty Chance.

Behind this careless trust lies an invisible tragedy. When I, a pharmacist with many years of experience, open such a “list of substitutes,” I can hardly contain my emotions. Unnamed authors strongly advise replacing the Mercedes with a VAZ, arguing that domestic cars also have four wheels. And sometimes they offer a scooter with the sauce of a car!

My pharmaceutical consciousness is boiling, having noticed in the list of “analogues” several pairs of completely different drugs. For example, miramistin is not chlorhexidine, and ersefuril has only one relationship to furazolidone: both drugs belong to the nitrofuran group. And this is just a drop in the ocean. Moreover, even replacements that are quite correct at first glance may be far from harmless.

Original drug and analogue

An original medicine is a drug that was first synthesized by the manufacturer. When buying an original, or, as pharmacists often say, a brand-name drug, we pay for for many years developments drug substance, for , for registration and so on. The manufacturer includes all these huge costs in the price, so original drugs are a priori much more expensive than generics (from the English generic), or analogues.

Manufacturers of analogues only synthesize the substance according to a well-known algorithm and prepare it from dosage form and pack. Their costs are minimal, and this has the most favorable effect on the price of the final product. Ideally, analogues should correspond to the brand drug in all respects, including effectiveness. But in reality?

The medicinal substance is the basis of the drug, its “core”. The effectiveness of the future drug depends on how well it is synthesized and how well all technological requirements are met. In addition, the medicine contains a lot excipients, which also affect bioavailability, absorption and other indicators, and therefore the final result.

In order to “comb” all manufacturers with one quality brush, in 1968, with the participation of the WHO, uniform standards for the production of drugs and dietary supplements, GMP (Good manufacturing practice), were adopted. The GMP system regulates all aspects of the production of medicines: from starting materials, the condition of premises and equipment to personal hygiene and personnel training. By the way, not all Russian enterprises have switched to GMP, and this gives another reason for thought.

But even if all requirements and standards are met, the generic may differ from the original. In 2000, American scientists published data from an independent study. After comparing the properties of the original drug Klacid and forty of its generics produced in 13 countries, scientists came to a disappointing conclusion. Not a single analogue has been recognized as equivalent to the original! And this despite the fact that all drugs were produced in accordance with GMP requirements.

We save correctly

And yet experience shows what to cook good fish soup You can make it from cheap fish if you follow all the cooking rules. First, you need to decisively click the mouse to remove sites with unfortunate lists from your bookmarks. Well, fluconazole of unknown production cannot work in the same way as the famous Diflucan, purified, standardized and verified to thousandths of a milligram!

Do not expect the same effect that the unique enzyme Creon gives from domestic pancreatin. Yes, they are the same active ingredients- the Internet did not deceive us on this. But making an enzyme that will not be destroyed in the stomach and intestines, but will be absorbed and, most importantly, will begin to act like its own, is a whole art. And so far it is not available to domestic enterprises.

Of course, an engineer or teacher cannot know pharmaceutical intricacies, and should not. Moreover, even the pharmacist has no right to interfere with prescriptions and change one drug to another. But a doctor who treats hundreds of patients clearly sees how the original and the generic work, and knows exactly the difference between Voltaren and diclofenac. Therefore, the decision to replace should only be made by the doctor.

Don't feel embarrassed and tell your doctor if you can't afford an expensive brand-name drug. Choice on modern market medicines allows you to replace the original medicine with a high-quality and more economical analogue that is not inferior to its progenitor in effectiveness. And be sure to close sites that offer to exchange awl for soap and never open them again.

Marina Pozdeeva

Photo by Alina Trout

The price of a drug does not always determine its quality; it is not always possible to understand why the consumer should overpay a large amount when active ingredient A medicine prescribed by a doctor can be found under a less popular name. Almost every expensive drug has a generic: its analogue in terms of action and chemical composition. You should always have a list of such tools at hand.

It should be noted that a 100% guarantee of the correctness of such a replacement cannot be given. Same active and auxiliary components may be present in different proportions, have varying degrees cleaning, etc. A number of expensive medications may be safer due to certain softening ingredients side effects, while the budget generic does not have any. In particular, this applies to antibiotics that have a negative effect on the body. Therefore, experts warn that any replacement, even with a generic and not an analogue, is carried out at the patient’s own risk, unless it has been discussed with the attending physician.

We bring to your attention a table of cheap analogues of expensive drugs with prices current for 2016. It should be said that only budget drugs whose cost does not exceed 150 rubles are included here, i.e. when the price difference really matters. Figures may vary depending on point of sale.

Main drug

Budget generic

Indications for use

Ambroxegal (110 rub.)

Ambroxol (50 rub.)

A drug that promotes the removal of sputum. Used for treatment wet cough, bronchitis in any form, pneumonia.

Aspirin-cardio (RUB 125)

CardiASK (35 rub.)

An analgesic that relieves fever and stops the inflammatory process. Used for angina pectoris, for the prevention of stroke and heart attack, circulatory disorders in the brain, thromboembolism.

Bepanten (280 rub.)

Dexpanthenol (140 rub.)

An ointment that triggers regenerative processes. It is used to restore the skin due to burns and wounds, to treat boils, dermatitis, and trophic ulcers.

Voltaren (400 rub.)

Bystrumgel, Fastum-gel (200 rub.)

Ketoprofen (60 rub.)

NSAIDs, analgesic, anti-inflammatory agent. Relieves fever. Used externally as an ointment for injuries and joint damage.

Diflucan (800 rub.)

Fluconazole (40 rub.)

An antifungal drug used in therapy against thrush, mycosis, histoplasmosis, cryptococcosis.

For nose (100 rub.)

Rinostop (30 rub.)

Zyrtec (350 rub.)

Ranitidine (50 rub.)

Antiulcer agent.

Zovirax (240 rub.)

Acyclovir (40 rub.)

An antiviral drug that helps eliminate herpes, smallpox and lichen.

Immunal (200 rub.)

Echinacea extract (50 RUR)

Immunostimulating agent used for prevention viral infections, in complex therapy with antibiotics to support the body.

Kapoten (120 rub.)

Captopril (15 rub.)

Antihypertensive drug ACE inhibitor. Used in combination treatment heart failure, with hypertension of any etiology, after myocardial infarction and diabetes mellitus with kidney damage.

Mezim (300 rub.)

Pancreatin (30 rub.)

Replenishes enzyme deficiency, helping the pancreas digest heavy foods more easily.

Maxidex (120 rub.)

Dixamethasone (40 rub.)

Glucocortecosteroid, used for endocrine diseases, cerebral edema, bronchial spasms, blood diseases, anaphylactic shock, rheumatism.

Midriacil (360 rub.)

Tropicamide (120 rub.)

Used for inflammatory processes of an ophthalmological nature, for examining the fundus, in therapy after operations.

Movalis (410 rub.)

Meloxicam (80 rub.)

NSAIDs, which relieve inflammation, fever and pain, can also be used in the treatment of the musculoskeletal system.

Normodipine (620 rub.)

Amlodipine (40 rub.)

Reduces blood pressure, used for vasospastic angina.

No-Shpa (150 rub.)

Drotaverine (30 rub.)

Antispasmodic, indicated for spasms of the digestive tract, brain, uterus, headaches, and urolithiasis.

Nurofen (120 rub.)

Ibuprofen (20 rub.)

NSAIDs that relieve fever and pain syndrome. It is on the list of essential drugs.

Omez (180 rub.)

Omeprazole (50 rub.)

It is used in antiulcer therapy, as well as for Zollinger-Ellison syndrome.

Panangin (170 rub.)

Perineva (310 rub.)

Perindopril (RUB 120)

ACE inhibitor used for ischemia, hypertension, heart failure, after stroke.

Sanorin (140 rub.)

Naphthyzin (15 rub.)

Nasal drops that have a vasoconstrictor effect. Used to treat sinusitis, rhinitis, and during operations of the nasal cavity.

Sumamed (450 rub.)

Azithromycin (90 rub.)

Antibiotic of semi-synthetic origin, used for infections respiratory tract, skin, soft tissues, digestive tract.

Troxevasin (220 rub.)

Troxerutin (100 rub.)

Flucostat (200 rub.)

Fluconazole (30 rub.)

An antifungal drug used in the fight against candidiasis of any type, mycosis skin, cryptococcosis.

Finalgon (320 rub.)

Capsicam (140 rub.)

An ointment with a local irritant effect, used for pain in muscles and joints caused by injuries or rheumatism.

Enap (110 rub.)

Enalapril (55 rub.)

Necessary for the treatment of hypertension of any ethnology and heart failure.

Even if you don't know exact name generic of an expensive medicine prescribed to you, you can look at its active component - there is a high probability that the budget analogue will have exactly the same name. For example, this scheme shows its effectiveness with acyclovir, potassium iodide, panthenol, fluconazole, etc.