Is pimafucin possible in the early stages. For pregnant

Due to the heavy burden on a woman's immunity during childbearing, it is harder for her body to defend itself against infection. Most often, expectant mothers complain about the manifestations of thrush, which is confirmed after the delivery of a genital smear. In such cases, experts recommend treatment with Pimafucin - it is the safest during pregnancy. Before use, you must carefully read the information about the features of its effects, dosage and contraindications.

Pimafucin - what is this medicine?

Pimafucin - antifungal antibacterial agent from the family of macrolides, which has a bacteriostatic effect due to the binding of styrene and blocking the process of joining fungal cell membranes. The active component of the drug is an antimycotic a wide range actions - natamycin, which acts on cell walls pathogenic microorganisms of causative agents of candidiasis, preventing their reproduction.

Specialists use this medicine to treat not only thrush caused by fungi candida albicans, but also any other lesions of a fungal infection:

• ear inflammation (otitis externa and otitis media);
• stomatitis;
• mycosis of the nail plate and skin;
• inflammation of the vulva and vaginal mucosa (vulvovaginitis, vaginitis).

It is prescribed even to pregnant women infected with fungi. It is considered absolutely safe due to the fact that it has a local therapeutic effect- does not penetrate circulatory system and through the placental barrier, therefore, according to medical statistics, not a single case of the negative effect of Pimafucin on the development of fetal organ systems has been registered.

Release form, dosage and effect on the body

Pimafucin is available in different dosage forms according to the area of ​​application (inside or outside). Only a doctor can choose the type and dosage of the drug or combine both forms:

• Ointment or cream 2% (1 gram contains 20 mg of natamycin) for external use, odorless, white or light yellow in color with a uniform thick texture. The cream is packaged in an aluminum tube with a volume of 30 grams, which is attached cardboard box and detailed instructions.
• Vaginal suppositories in the form of a milky-white torpedo containing 100 mg of antibiotic in 1 suppository. Additional substances: adipic acid, sodium bicarbonate, polysobat, cetyl etal, solid fat, sorbitan trioleate. The drug is packed in cardboard boxes with three 3 or 6 strips.
• Round white tablets with an enteric coating. 1 piece contains 100 mg of natamycin and 160 mg of auxiliary components: potato starch, lactose monohydrate, magnesium stearate, polyvinylpyrrolidone. Tablets are packaged in 20 pieces in dark glass bottles and cardboard packs with instructions.

Instructions for use of the drug

Experts emphasize that not a single drug, even the safest, can be selected independently. Pimafucin also has its own characteristics of use and duration of the course, depending on the form of release:

• The cream is applied to the affected areas of the skin or nails, laid in ear canal up to 4 times a day during the course, which is individually selected by the attending specialist, until the symptoms disappear completely.
• Suppositories are treated for 5 days or a week. It is injected deep into the vagina, 1 piece per day. It is necessary to carry out in advance hygiene procedures, lie on your side and wait a bit until dissolved.
• The tablet form of Pimafucin is taken for a week, 1 tablet 4 times a day.

When planning

There is an opinion that when planning a child, Pimafucin in the form of suppositories can affect the fertility of spermatozoa that enter the vagina. Experts do not confirm this information and offer to hand over everything before conception. necessary tests, then undergo treatment and start conceiving a healthy baby.

1 trimester

In the first three months after pregnancy, a woman's hormonal background and in connection with this, symptoms of thrush may appear, so the gynecologist prescribes Pimafucin in the form of suppositories. Tablets in the first trimester are not recommended due to the manifestations of toxicosis.

2 trimester

Treatment of a fungal infection during the period from 4 to 6 months of pregnancy (2nd trimester) becomes much easier, because you can pick up other, more potent drugs if Pimafucin does not cope with developing disease. In addition, the baby is protected by the mucous plug of the uterus and the infection cannot penetrate to it. The specialist prescribes the drug in tablet form so that by the time of birth the child passes through healthy birth canal and didn't get infected.

Often, doctors recommend simultaneous treatment of both sexual partners and prescribe Pimafucin tablets in combination with another antifungal ointment or suppositories. The duration of treatment and additional medicines are determined by the doctor according to individual indications after passing the tests (vaginal smear, bacterial culture of urine).

3rd trimester

Experts recommend undergoing a prophylactic course of treatment before childbirth (at week 38), if during the planning period or at early dates pregnancy was a case of recurrence of thrush. Also, in the last stages of gestation, intestinal candidiasis may appear, which requires taking Pimafucin for 3 days.

With thrush

Thrush does not pose a danger to the fetus, it only delivers discomfort future mother. However, there is a possibility of infection of the baby in the process labor activity, therefore, it is necessary to treat thrush, especially since Pimafucin does not affect the intrauterine development of the child, but only eliminates fungi and the consequences of their activity.

Side effects and contraindications

With careful observance of the instructions, Pimafucin does not have a negative effect on the body, in rare cases adverse reactions. In the first days of taking the tablets, nausea, loss of appetite, and vomiting may occur. When using suppositories and ointments, local allergic reactions may occur in the form of itching, burning and redness of the skin areas treated with the drug.

Pimafucin has no contraindications and experts can recommend it during pregnancy and during breastfeeding. Limitation of use may be due to individual intolerance (lactase or fructose deficiency) or allergic reactions to any auxiliary component of the drug.

Are there analogues of the drug?

With absence therapeutic effect from Pimafucin, the doctor can replace it with a drug similar action but with a different active or excipient. The pharmaceutical industry offers many analogues:

• Natamycin is a drug containing a similar active ingredient, but without auxiliary components that soften the effect of the antibiotic on the body, which is why Natamycin causes serious harm to the patient's digestive system.
• Funzol - antifungal agent based on fluconazole in the form of a solution for infusion, powder for suspensions, capsules and syrup. It has many contraindications, including the period of breastfeeding.
• Ecofucin - complete analogue Pimafucin in the form of suppositories, which is cheaper (200 - 300 rubles). Ecofucin is most often prescribed to pregnant women for the treatment of thrush.
• Funginok - tablets with active component ketonazole (200 mg), are used to treat fungal infections of the skin. Prohibited for use during pregnancy.
• Terzhinan - tablets for vaginal administration with the following active substances: ternidazole, neomycin sulfate, nystanin, prednisolone sodium metasulfobenzoate. Applicable for inflammatory process, complicated by additional pathology, and also require a longer course of treatment and can cause allergies. Terzhinan is prohibited during pregnancy, because the substances penetrate the placental protection and adversely affect the fetus.
• Clotrimazole is a drug that has a more aggressive effect on the body and causes intoxication in case of overdose (we recommend reading: Clotrimazole suppositories: instructions for use in the 1st trimester of pregnancy). Not recommended for the treatment of pregnant women in the 1st trimester and breastfeeding.
• Livarol - vaginal suppositories with the active substance ketoconazole. They are prescribed in case of recurrence of thrush, if drugs of a more gentle action do not cope. Livarol can provoke allergic reactions and severe irritation of the mucous membranes and skin.
• Hexicon - antiseptic medicine based on chlorhexidine bigluconate, available in several forms (gel, suppositories, tablets) (we recommend reading: Hexicon suppositories: indications for use during pregnancy). It can be used at all stages of pregnancy, but not combined with iodine and soap solutions.
• Betadine is an antibacterial and antiseptic drug that is often used to treat wounds, burns, postoperative sutures. The composition of the drug contains povidone-iodine, which can affect the functioning of the thyroid gland.

It is not for nothing that thrush is portrayed in advertising ironically and even with some degree of anger - an annoying disease occurs at the most inopportune moment, and the symptoms are such that at least do not go out to people. Plus, a relapse if the therapy is carried out untimely or not very competently.

Pregnant women in the 1-2 trimesters are especially affected by candidiasis. As a rule, the disease most easily overtakes them - future mothers, who are practically deprived of reliable immunity.

It should be noted that candidiasis is actively manifested in pregnant women precisely in the early stages, creating an additional problem for both women and attending physicians: how and with what to treat the disease, if the use of drugs during pregnancy is undesirable, and, apart from medicines, there is no way to get rid of thrush and a number of others. fungal diseases.

"Companion", which is absolutely not needed

No matter how hard the future mother tries to avoid candidiasis, this is far from always possible, and weakened the immune system- the main reason for the susceptibility of pregnant women to infectious diseases.

Serious violations of the microflora of the vagina become a consequence of a weakened immune system and create favorable conditions for the development of Candida fungi.

Is it possible to avoid a pregnant unpleasant fate and somehow prevent the disease? Preventive measures against candidiasis, women should carry out even before pregnancy, having comprehensively examined the body, and if hidden diseases genitourinary system, cure them.

If prophylaxis must be carried out already during pregnancy, then a woman must adhere to certain rules:

• refuse underwear made of synthetic materials;
• as often as possible, change, wash with high quality and iron linen made of natural "breathable" fabrics before putting on;
• do not wear tight-fitting things, give up thongs;
• in the heat, do not wear synthetic tights;
• do not walk in a wet swimsuit for a long time: take a spare set both to the beach and to the pool;
• observe intimate hygiene, do not get too carried away with very fragrant hygiene products with a chemical component;
• dry the genitals after bathing;
• wash from front to back (as well as wiping);
• before intimate hygiene wash your hands well, make sure that there is no contamination under the nails;
• abandon the douching procedure so as not to wash out the beneficial microflora;
• eat a balanced diet.

Candidiasis is dangerous and relatively safe

The clinical picture of candidiasis in each individual case has distinctive features: symptoms different forms thrush takes on a completely different look, and sometimes it is simply impossible to notice. And this is very dangerous, because the disease will develop anyway and its peak may occur during the most defenseless period of pregnancy - the first or second trimesters.

We propose to consider this not very attractive picture closer, in order to recognize candidiasis, if necessary, even if it wants to “encrypt”.

1. The form - carriage. Symptoms - absent, candidiasis can be diagnosed only during the examination after receiving a smear analysis.

   Treatment should begin immediately so that the disease is not transmitted to the newborn baby during childbirth.

2. Acute form of the disease. Symptoms:
   • constant burning sensation in the vagina, aggravated during urination, wearing too tight underwear, after taking a warm bath;
   • the appearance of thick secretions of a curdled type;
   • swelling and redness of the external genital organs;
   • pain when urinating.
3. Chronic form(persistent candidiasis). Symptoms are temporarily absent, and the woman may have the illusion full recovery but after a while the symptoms return. They are identical to the symptoms acute form diseases.

   If the disease in this form is found in a woman in the 1-2 trimesters, then most likely the infection occurred long before pregnancy. Therefore, once again we focus your attention on the mandatory examination at the stage of pregnancy planning.

Pimafucin and sauerkraut

If fungi of the genus Candida are detected on the mucous membrane of a pregnant woman, the attending physician must immediately begin therapy, choosing the most best option medication.

Pimafucin is traditionally considered the safest during pregnancy. And although innovative doctors now and then declare that the drug is outdated, this does not negate its effectiveness.

The presence of an antibiotic in the composition of the preparation is somewhat frightening for expectant mothers, but this is typical for antifungal group medicines - otherwise it will not be possible to get rid of the disease.

So that the presence of an antibiotic does not really bother women, many doctors (from conservatives) advise during the use of the drug to increase the number of dishes from sauerkraut and pickles in your diet (not pickled - just salted, knowing the fermentation process). The probiotics found in these foods help prevent urinary tract infections.

In addition, such food is very loved by pregnant women, especially in the first weeks, when they are drawn to sour. And in alliance with Pimafucin, sauerkraut works just fine.

Composition and pharmacokinetics of Pimafucin

The active substance of the drug is a broad-spectrum antibiotic natamycin.

Once in the body, it binds the particles of the membranes of negative cells, contributing to their destruction.

Natamycin is not absorbed into the bloodstream when using suppositories or cream, which means it is safe for the fetus. To get a result from the use of the drug, a woman needs to undergo a long course of treatment - Pimafucin is non-toxic and acts very slowly. This is what caused the fact that some modern doctors recognized the drug as obsolete.

Release the drug in the form of tablets, rectal suppositories, vaginal suppositories, creams for external use.

Dosage and duration of therapy

In the acute form of candidiasis, the doctor, except vaginal suppositories, appoints a pregnant woman also Pimafucin tablets.

Taking the medicine inside accelerates the process of destruction of Candida fungi in the intestines and improves the effect of exposure. But the question arises: how much does a pregnant woman risk when taking pills. After all, if the probability of absorption of the active substance of the drug from the mucous membranes is minimized, then through the walls of the stomach the antibiotic can enter the bloodstream, although pharmacokinetic studies of the drug prove the opposite.

In any case, when using Pimafucin in the form of tablets, care should be taken.

If the standard dosage of Pimafucin in the form of suppositories is one suppository per day, then the tablets should be prescribed by developing an individual schedule. The treatment course with the use of tablets is at least two weeks.

Pimafucin cream is applied to the affected area 1-2 times a day, the use of this form of medication is considered auxiliary. The course of treatment is prescribed by the doctor.

Side effects

Often the use of antifungal vaginal suppositories causes side effects that are very difficult to distinguish from the symptoms of the disease: the same burning sensation, the same pain sensation, the same redness.

If you notice such manifestations during therapy, be sure to tell your doctor about it and ask to change the drug.

Other side effects:

• nausea;
• allergic reactions;
• vomit;
• stool disorder.

Harmless means ineffective?

Let us return to the topic of a long course of treatment and the safety of the drug for the fetus and the pregnant woman. Harmlessness is often perceived as a synonym for inefficiency. Is this the case with Pimafucin, which some doctors have stopped prescribing for the duration of therapy and the fact that it does not help all women.

The opinions of specialists about this drug drastically differ, some doctors prescribe suppositories throughout the entire period of pregnancy, absolutely not fearing for the health of the mother and fetus, while others are guided by nuances when prescribing clinical picture and be careful, others do not consider Pimafucin effective tool, and avoid its appointment for this very reason.

Pimafucin by trimester

1 trimester

Assign in the form of candles or cream. The course of treatment is 3-6 days, but depends on the neglect of the process. Apply at night, in the supine position. Most experts advise on the eve of a planned pregnancy to undergo an examination, cure all chronic diseases urogenital system and strengthen the immune system in order not to use medications in the early stages. It is undesirable to take Pimafucin tablets in the first three months of pregnancy.

2 trimester

In the second trimester, the use of suppositories and Pimafucin cream is allowed. Tablets are prescribed in case of urgent need.

3rd trimester

In the third trimester, it is possible to prescribe all forms of the drug.

A drug such as Pimafucin suppositories during pregnancy or Pimafucin tablets are often prescribed to expectant mothers for the treatment of thrush (and, we note, every third pregnant woman has it at least once in 40 weeks).

Is the use of this drug in expectant mothers allowed? How effectively does it cope with the task - to cure thrush?

First about the thrush

Candidiasis, or as it is also called "thrush", is perhaps the most common disease among all women, and pregnant women are no exception. The causative agent of the disease are fungi - Candida, the increase in the number of which causes various unpleasant symptoms and inflammation. Candidiasis usually occurs against the background of reduced immunity, for example, due to colds or frequent use of antibiotics.

Candida mushrooms

Speaking of reasons, causing thrush In addition to the above, there may be the following:

• infection from a sexual partner;
• the presence and reproduction of pathogenic fungi in the intestine;
• poor nutrition;
• regular wearing of synthetic underwear.

How to understand that you have thrush? Pay attention to the main symptoms:

• curdled discharge from the vagina;
• light white discharge with a sour smell;
• irritation of the external genital organs;
• itching and burning of the external genitalia and vagina;
• discomfort during urination or sexual intercourse.

All women have mushrooms of the Candida family, only they are normally found in minimal quantities and are unable to cause harm. With a decrease in immunity, their number increases, and then problems arise.

If you observe one or more of the symptoms of thrush, you should consult a doctor.

Thrush during pregnancy

Thrush is an unpleasant disease at any time, but it can be not only unpleasant, but dangerous during pregnancy. Why? Candidiasis can be detrimental to the normal course of pregnancy. In some cases, it causes thinning of the fetal membrane (amnion) and provokes its rupture. And it doesn't always happen on time. In addition, with active inflammation, the baby, passing through the birth canal, can become infected with thrush.

Most often, thrush occurs during pregnancy curdled secretions from the vagina

For these reasons, the treatment of thrush in expectant mothers requires the supervision of a doctor and the appointment of exclusively harmless drugs that do not affect the development of the fetus and the health of the woman herself.

If you do not seek prescriptions and control of the condition of the disease from a doctor, the disease can turn into chronic stage and cause irreversible changes in the body, and even lead to infertility.

Why Pimafucin?

Pimafucin - modern medical preparation, which is an antifungal antibiotic broad action, fungi of the Candida family are most sensitive to it. The composition of Pimafucin includes natamycin, which destroys the cells of fungi, thereby killing them. The drug does not penetrate the bloodstream, which means it does not cross the utero-placental barrier, which means it will not affect the development of the unborn baby in any way. In addition, the drug is used by dermatologists for fungal infections of the skin, can be used in nursing mothers and even babies.

Pimafucin release form

Pimafucin is produced in convenient forms:

• vaginal suppositories or suppositories Pimafucin - act directly on the mucous membrane and are especially popular among pregnant women;
• Pimafucin tablets are usually used for chronic Candidiasis or in severe cases when the disease has spread to abdominal cavity. The tablets are coated, which dissolves not in the stomach, but in the intestines, which reduces the risks side effects on the stomach;
• Pimafucin cream is used for local external action, acts on damaged areas of the skin or mucous membranes; can be used by a partner to prevent recurrence of the disease.

Pimafucin is prescribed not only for thrush, but also for a number of others, no less serious illnesses. It may be, as we have said, fungal diseases intestines, colpitis, vulvitis, vulvovaginitis, ringworm, ear mycosis, fungal diseases of nails and skin.

This drug is taken as prescribed by the attending physician after passing tests and confirming the presence of pathogenic microflora in the body.

Terms of use of Pimafucin

The appointment, as well as the calculation of the dosage of the drug Pimafucin, is made by the attending physician based on how severe the disease is.

Treatment with Pimafucin tablets lasts an average of seven to ten days, with candles - three to nine days.

The medicine is taken in a course until the symptoms disappear (and possibly a couple of days after).

Pimafucin during pregnancy

Pimafucin is approved for use throughout pregnancy, from the first trimester to the stage of preparation for childbirth.

Usually, in the first trimester, doctors try to limit the intake of drugs by a pregnant woman as much as possible, since the placenta is not yet formed, and all the components in the mother's blood go to the baby. But even in this trimester, the use of Pimafucin is allowed, since it is not absorbed into the blood and has local action. Usually at this time, Pimafucin is used in the form of vaginal suppositories.

In the II trimester, as in the most “safe” and prosperous, it is allowed to take many drugs that are prohibited in the early and later dates pregnancy. The fetus is protected, the expectant mother is calm. During this period, you can use "heavy artillery" and take pills for thrush if the candles do not cope.

The use of Pimafucin is safe during pregnancy

Remember! Even despite the safety of the drug, Pimafucin should be taken strictly according to the doctor's prescription and after the examination.

The attending physician will determine the severity of the disease and the required dosage of the drug. Do not self-medicate, because the signs of thrush that seem at first glance may turn out to be symptoms of a more serious disease, which can only be determined after passing the necessary tests.

Side effects and contraindications for taking Pimafucin in pregnant women

Usually this drug is tolerated by women easily and without consequences. In some cases, the following side effects occur:

• itching and burning from taking Pimafucin in the form of vaginal suppositories;
• irritation, redness at the points of contact of the drug with the mucous membrane;
• indigestion and nausea from the use of a tablet form;
• increased signs of toxicosis and general deterioration well-being in pregnant women.

The listed side effects are rare, and they occur mainly due to individual intolerance to the components of the drug.

If you notice symptoms of side effects of Pimafucin, stop taking the medicine and consult a doctor.

There are no contraindications, except for individual intolerance to the drug or its components. the active substance natamycin does not penetrate into the blood, which means that it cannot harm the expectant mother and fetus.

Also a big advantage of this drug is the possibility of using the drug for pregnant women and women who are breastfeeding.

Information about the drug

Pimafucin is available in three forms: suppositories (suppositories), tablets, ointment.

The composition of the tablets: main substance - natamycin. Excipients these are starch (potato), talc, sucrose, titanium dioxide, kaolin, polyvinylpyrrolidone, magnesium stearate, lactose, gelatin, methyl parahydroxybenzoate, calcium carbonate, beeswax (white).

Cream composition: main substance also natamycin. Excipients: purified water, decyloleate, propylene glycol, cetyl wax ether, cetostearic alcohol, sodium lauryl sulfate, propyl parahydroxybenzoate, methyl parahydroxybenzoate.

Composition of vaginal suppositories: main substance - natamycin. Excipients: adipic acid, cetyl alcohol, solid fat, sorbitan trioleate, polysorbate 80, sodium bicarbonate.

Candles after administration under the influence of body temperature quickly dissolve and in this way the medicine is evenly distributed into the vagina. If a woman has chronic candidiasis, then it is additionally necessary to take pills or use a cream.

During therapy sexual life you can continue. During menstruation, treatment is temporarily stopped.

A woman needs to focus on her feelings, because it is possible allergic reaction for alcohol.

Indications for use

• fungal skin diseases and appendages of the skin, that is, nails;
• candidal vulvovaginitis;
• fungal infections gastrointestinal tract that appeared due to weak immunity, taking antibiotics and cytostatics, cachexia. Including intestinal candidiasis, acute pseudomembranous and atrophic candidiasis;
• cumulative treatment if a systemic fungal disease is present.

Signs of vaginal candidiasis:

• severe itching, also burning of the genitals;
• painful sensations of the membrane of the vulva of the vagina;
• redness of the genitals;
• copious white discharge from the vagina, like a curdled mass;
• painful burning during urination due to urine getting into irritated areas;
• the process of sexual intercourse becomes painful, the woman is irritated;
• possible urination disorders;
• foul-smelling vaginal discharge (sour).

Candidiasis is not dangerous for a pregnant woman and a child, but the symptoms are so unpleasant that it is better to get rid of them and feel good. During the bearing of a child, thrush often manifests itself due to the load on the body and a decrease in immunity. During the treatment of candidiasis, the course of therapy must be completed by both partners. both man and woman.

can be triggered during pregnancy due to such problems, as diseases of the chronic nature of the genitourinary system, beriberi, vaginal dysbacteriosis and problems with the gastrointestinal tract.

Also, a pregnant woman has an increased level female hormones which are ideal favorable condition for candidiasis.

Some medical sources narrate information that during pregnancy, in order to avoid vaginal dysbacteriosis, it is advisable to eat less sweets.

Dosage and duration of taking the drug during pregnancy

The use of Pimafucin during all phases of pregnancy does not differ in dosage or any other features.

Pills used to treat:

• intestinal candidiasis. Drink, regardless of food intake;
• fungal diseases of the appendages of the skin, drink one tablet four times in 24 hours and use of the cream, duration of therapy two to three months;
• vaginal candidiasis. Using the suppository and taking the tablets, one tablet four times in 24 hours. The course of therapy is 10 to 20 days;
• skin candidiasis. taking pills, 1 piece / 4 times a day and the use of the cream, the duration of treatment - week (7 days);
• onychomycosis. Taking pills 1 piece 4 times a day and use of cream, treatment at least 2-3 months.

suppositories applied to treatment of vulvovaginal candidiasis. 1 suppository insert deep into the vagina, in a supine position, before the night's rest. A course of treatment selected on an individual basis 3-7 days. After the symptoms disappear, it is necessary to use suppositories for a few more days.

Cream used for treatment nail candidiasis, treatment ringworm, treatment skin candidiasis. All this is treated according to one scheme: apply the cream one to four times a day to areas that are infected. Duration of therapy approx. 14-21 days.

Side effects

At the beginning of treatment with tablets, nausea, vomiting are possible, in the future side effects disappear. When using candles or cream, there may be a burning sensation or irritation of nearby tissues.

Drug overdose is unlikely, but in any situation, treatment should occur under the supervision of a physician and with clearly indicated doses.

In general, the drug is very well tolerated, the only exception is if you are prone to allergies to any component of the drug. It is prescribed even for babies.

Means can be combined with other drugs (any), negative impact not found.

Effective analogues

Analogues are considered means that have the same indications for use and the same functions. The difference lies in the manufacturer, which entails a difference in price.

Substitutes for Pimafucin: Primafungin, Funzol, Tsiskan, Fungizone, Funginok, Fungavist, Tsinkundan.

All drugs are sold freely in pharmacies, a prescription is not needed.

The appointment of the drug and its replacement with an analogue is possible only after consultation and examination by a doctor. Do not self-medicate, take care of your health and the health of your baby.

One of the few drugs approved for the treatment of thrush during pregnancy is Pimafucin. After all, the drugs that are prescribed to the expectant mother should be not only effective, but also safe for the fetus. This tool is just that. Consider the instructions for the use of "Pimafucin" during pregnancy, indications, contraindications, analogues and reviews of patients.

General information about the drug

Main active substance"Pimafucin" is natamycin. This substance belongs to macrolide antibiotics and is effective against many pathogenic fungi. The causative agents of candidiasis are most sensitive to its effects.

Different forms of the drug additionally contain auxiliary components. They will be discussed in more detail below.

The main advantage of "Pimafucin" during pregnancy is that the drug, even in the form of tablets, is practically not absorbed into the blood. This means that it is completely safe for the fetus and does not affect its development.

Forms of release of the drug

There are three main forms of release of the drug:

1. Pills. Covered with a white shell, which protects the product from the effects of stomach enzymes and dissolves only after entering the intestines. Due to this, the drug can be used for fungal infections of the lower sections. digestive system. In addition to the main active ingredient, Pimafucin tablets contain additional substances such as beeswax, potato starch, lactose, sucrose, talc, gelatin, kaolin and others.
2. Cream. Has a white or slightly yellowish tint. Created for local application. The composition of the cream "Pimafucin" includes natamycin and auxiliary components: wax, water, cetylstearyl alcohol, oleic acid ester and decyl alcohol and others.
3. Vaginal suppositories. During pregnancy, Pimafucin suppositories are most often prescribed. They have White color with a yellow or brown tint. In addition to the active substance, the composition of suppositories includes sorbitol, solid fat and others.

Indications for the use of the drug

The use of "Pimafucin" during pregnancy may be necessary in the development of diseases caused by the reproduction of fungi. It is usually prescribed for:

• vaginal candidiasis;
• vaginitis;
• vulvovaginitis;
• fungal infections of the mucous membranes, skin, outer and middle ear.

These pathologies cause itching, burning, discomfort and adversely affect the course of pregnancy. In especially severe cases, candidiasis (thrush) can lead to thinning of the membranes of the fetus, resulting in their premature rupture.

In addition, the use of Pimafucin suppositories during pregnancy can protect the child from infection with thrush during childbirth. Therefore, often in the last weeks he is appointed to preventive purposes.

Contraindications to the use of the drug

Despite the fact that natamycin is a broad-spectrum antibiotic, the use of Pimafucin during pregnancy is contraindicated only if there is an individual intolerance to the components of the drug. Otherwise, there is no reason to refuse this tool and its replacement with analogues.

Side effects

In the instructions for the use of Pimafucin suppositories during pregnancy, as well as other forms of the drug, the manufacturer warns about possible appearance some side effects:

• irritation of the mucous membranes;
• itching;
• nausea and vomiting;
• burning sensation;
• digestive disorders (diarrhea, constipation);
• edema.

As a rule, unpleasant symptoms disappear with the end of the medication. If this does not happen, you need to seek help from specialists. You will also need to choose another remedy and complete the course of therapy prescribed by the gynecologist.

The use of the drug in the first trimester of pregnancy

Unfortunately, for infections without pharmacological preparations can't get by. The same applies to thrush. For a complete recovery, douching or taking decoctions will not be enough. medicinal plants. After all, the main goal to be achieved is getting rid of the pathogen.

The use of "Pimafucin" during pregnancy in the 1st trimester is not prohibited. Even taking into account that active substances in a small amount are absorbed into the mother's blood and penetrate to the child, this will in no way affect his development. During this period, it is best to give up tablets and use suppositories or Pimafucin cream.

The use of the drug in the second trimester of pregnancy

In the second trimester, the list of allowed medications large enough, and "Pimafutsin" is also one of them. From 14 to 26 weeks, the drug can be used in any convenient form, including tablets.

During this period of pregnancy, the placenta is already fully formed, which reliably protects the baby. If there is no effect from the use of Pimafucin, the doctor can replace it with others, more potent means.

The use of the drug in the third trimester

According to the instructions, "Pimafucin" during pregnancy in the third trimester is also not prohibited for use. It is usually prescribed for mild to moderate thrush. severe forms ailments will require the use of other, more strong drugs("Terzhinan", "Viferon", "Gino-Pevaril" and so on).

In the third trimester, the doctor may prescribe the use of Pimafucin for prophylactic purposes. This is especially true in cases where a pregnant woman has already encountered thrush at an earlier date. Thus, it will be possible to protect future mother from the recurrence of pathology, and her baby - from infection during passage through the birth canal.

Doses and duration of therapy

The required number of applications of "Pimafucin" during pregnancy depends on the severity of the disease. Therefore, we will consider only standard dosages that can be changed by the doctor on an individual basis.

1. Instructions for use of tablets "Pimafucin" during pregnancy. Usually this form of the drug is used to treat chronic candidiasis of the mucous membranes and skin, as well as fungal infections in the intestines. In this case, the course of treatment will last about a week, and the patient will have to take 1 tablet 4 times a day.
2. Instructions for candles "Pimafucin" during pregnancy. Suppositories are used to treat thrush, vulvovaginitis and vulvitis. Only 1 candle per day is needed. The duration of the course will be within 5-7 days. At the same time, there are some features of the use of Pimafucin candles. They need to be inserted into the vagina in the supine position, do it at night before going to bed. Do not be afraid if, after using this form of the drug, the next day the pregnant woman finds unusual discharge. This gradually leaves the candle dissolved in the vagina.
3. Instructions for use of the cream "Pimafucin" during pregnancy. It is most convenient to use it for the treatment of fungal diseases of the nails and skin. Ointment thin layer applied to the affected areas up to 4 times a day. The duration of treatment will depend on how quickly the symptoms of the disease disappear. At the same time, it will be necessary to smear the affected area with cream for a few more days after the symptoms of the disease have been eliminated.

Despite the fact that "Pimafucin" is considered safe drug, it can be used only as prescribed by a doctor. Previously, the specialist will have to assess the severity of the disease, calculate the required dosage and duration of therapy. It is very important to follow all his recommendations!

The cost of the drug

The cost of "Pimafucin" may vary slightly, depending on the pharmacy and the region of residence. The average prices for the tool are:

1. Candles (3 pieces per pack) - 250-300 rubles.
2. Candles (6 pieces per pack) - 500-700 rubles.
3. Tablets - 410-490 rubles.
4. Cream - 270-300 rubles.

As you can see, the drug has a relatively low cost. What about its effectiveness? This will be told by the reviews of patients who have undergone a course of treatment with Pimafucin.