Hofitol solution for oral administration, instructions for use. Hofitol is an effective remedy for the treatment of kidney diseases

Instructions for use:

Hofitol is a drug plant origin with pronounced choleretic and diuretic properties, reducing azotemia.

Pharmacological action

Main active ingredient The composition of the drug Hofitol is artichoke leaves, rich in a complex of vitamins, microelements and other biologically active substances.

Due to the action of phenolic acids in combination with cynarin, Hofitol has a choleretic and hepatoprotective effect.

Inulin, ascorbic acid, B vitamins, in particular B1 and B2, as well as carotene have a normalizing effect on the body’s metabolic processes.

In addition, important pharmacological effects of the drug, according to reviews of Hofitol, are increased urine excretion and the diuretic effect of the drug.

Release form of Hofitol

Hofitol is available in three different forms.

Pills brown, covered with a shell. IN pharmacy chains There are two types of packaging: 60 or 180 tablets in bottles or blisters;

Oral solution with a volume of 120 ml, placed in a bottle;

Solution for injection. Packaged in 5 ml ampoules with a self-breaking tip. Ampoules in the amount of 5 pieces are placed in a package.

Indications for use of Hofitol

The drug is usually used as part of complex therapy. Indications for Hofitol are listed below:

Noncalculous cholecystitis in chronic form;

Biliary dyskinesia of the hypokinetic type;

Hepatitis in chronic form;

Chronic nephritis;

Cirrhosis;

Renal failure in chronic form.

Contraindications

Hofitol and drug analogues are usually well tolerated, but are contraindicated in some groups of people. Their list is given below:

Patients with cholelithiasis;

Patients with obstruction biliary tract;

Patients diagnosed with acute diseases of the kidneys, liver, urinary and biliary tract;

Patients with hypersensitivity to the components of the drug.

The instructions for Hofitol in the form of tablets warn that the drug cannot be prescribed to children under 6 years of age.

Instructions for use of Hofitol

The dosage when taking the medicine depends on the age of the patients.

For adults, according to the instructions for Hofitol, it is recommended to take the drug orally 3 times every day, 2.5-5 ml of solution or 2 or 3 tablets. The course of treatment is most often 2 or maximum 3 weeks.

Children Hofitol should take 1 to 2 tablets daily before meals. The drug solution is taken in a quarter or half of the dose prescribed for adults, also 3 times a day. Duration of treatment is up to 3 weeks. It should also be taken into account that, according to medical reviews about Hofitol, the medicine is intended for the treatment of children over 6 years of age.

If it is necessary to repeat the course of treatment, you should obtain medical advice.

Side effects of Hofitol

As a rule, no side effects occur during treatment with the drug. However, in extremely rare cases, adverse reactions may occur even with obvious indications for Hofitol and the absence of contraindications. First of all, this reaction of the body is caused by long-term use of the drug in high doses.

Side effects include allergic reactions and diarrhea.

Special instructions

The use of Hofitol during pregnancy and breastfeeding is permissible only with the permission of a doctor and constant medical supervision.

Hofitol's analogs

Drugs similar in composition and effect on the body to Hofitol include:

Artichoke extract;

Holebil.

Storage conditions

Hofitol is stored at a temperature not exceeding 25°C in a place out of reach of children. The shelf life, if all conditions are met, is 3 years for tablets and 4 years for solution.

For stagnation of bile and other problems with gallbladder recommended to take choleretic drugs. One of the most popular prescriptions for gastroenterologists is taking Hofitol tablets.

Description of the medicine

Hofitol is produced in France by the company Rosa-Fitofarm, and is available in two forms - tablets and a solution for internal use. The price of the medicine is 350 rubles/60 tablets, 390 rubles/120 ml of solution.

The composition contains artichoke extract - an extract of phyto-raw materials.

This remedy belongs to the group of choleretic drugs of natural origin. In addition to 200 mg of extract (one dose for both forms), there are also additional ingredients:

The tablets are round, convex on both sides, brown (coated). The solution has an original smell, which is achieved through the introduction of orange flavor, as well as the natural aroma of artichoke extract. Tablets are sold in 60/180 packs, in blisters - 12-30 pieces. The syrup is sold in a dark glass bottle.

Effect of the drug

The main indications for use are based on the action of the drug - choleretic. Artichoke extract includes many useful biologically active components - pectin, chlorogenic acid, polysaccharides, caffeic acid. There are also mineral salts, vitamins, potassium, inulin, and cynarin. It is the latter component in combination with phenolic acids that provides choleretic effect- it dilutes bile, preventing the formation of flakes, sediment, and stones. As a result of taking Hofitol, it increases the secretion and flow of bile.

The drug has a hepatoprotective effect, protecting hepatocytes from damage.

During course admission it is optimized functional state liver tissue.

Vitamins B, beta-carotene, and inulin also have a noticeable beneficial effect on metabolism. They regulate metabolism, especially fat metabolism. This allows the medicine to produce the following effects:

Such actions allow the drug to be used as part of the diet for those who are trying to control fat levels. Due to the presence of inulin, the drug lowers blood sugar. Another effect of Hofitol is diuretic; it removes excess fluid from the body, and along with it, excess urea.

Indications for use

Hofitol is used for biliary dyskinesia, especially with delayed bile evacuation (decreased motility). The drug helps relieve the unpleasant symptoms of pathology of the hypokinetic type:

For cholecystitis, the remedy will also be useful - it will prevent the formation of stones, reduce symptoms, and help eliminate inflammatory process. Due to the risk of bile dilution and the onset of stone movement, Hofitol can only be used in chronic acalculous forms of the pathology (tablets and solution will also serve as a prevention of stone formation).

The drug is indicated for liver pathologies - cirrhosis, chronic hepatitis. In case of alcoholism, it promotes the renewal of liver tissue, helps prevent hepatosis and cirrhosis. The diuretic effect makes Hofitol useful for nephritis in a recurrent form, renal failure. Its course is prescribed after poisoning with nitrates, alkaloids, heavy metals, and other substances toxic to the liver.

Hofitol is also indicated for obesity, atherosclerosis, coupled with by special means, at urolithiasis and uraturia. Hofitol is used for jaundice in newborns, in pregnant women according to strict indications (late gestosis, early toxicosis, preeclampsia). It is known that taking the drug stimulates blood circulation in the placenta and reduces the formation of edema.

Contraindications and side effects

It is forbidden to take the drug if you already have stones, especially when cholelithiasis has led to partial blockage of the bile duct. Any acute pathologies kidneys, liver, other internal organs also belong to the list of contraindications to therapy.

The drug will cause harm in severe cases liver failure.

Other contraindications include intolerance to the components, deficiency in the body of sucrose, isomaltose (for liquid dosage form).

Tablets are not given to children under 6 years of age; this contraindication does not apply to the solution. During lactation and pregnancy, use is carried out only under the strict supervision of a specialist! Possible adverse reactions include:

If you take Hofitol for too long a course, diarrhea develops quite often. When this happens, and diarrhea is accompanied by abdominal pain, you should stop taking it. Due to the nature of the composition auxiliary components Immediate and delayed allergic reactions are possible (within 72 hours). The liquid form includes sucrose in a volume of 0.04 XE/day, which must be taken into account when diabetes mellitus.

Instructions for the medicine

Tablets are taken by adults and children over 6 years of age. Dosage - 2-3 tablets three times a day. It is enough for children to drink 1-2 tablets in the same regimen. Treatment is carried out before meals, the course is 2-3 weeks. It can be repeated if necessary. The solution is drunk 2.5-5 ml three times a day, depending on the pathology, the dose is chosen by the doctor.

In children, the dose of the solution is 1/4 that of an adult. The maximum daily dose is 1.2 g/day for people over 12 years of age. For pregnant women, the optimal dose is 400-600 mg/day. Doctors usually recommend taking tablets that do not contain flavorings (the latter can themselves provoke an allergy). The course for pregnant women is 14 days. In children and adolescents, the main indications for treatment with Hofitol are:

Newborns are given a solution of 5-10 drops/dose three times a day. Dissolve the dose in 5 ml of water or more. Usually the course is 9-14 days, during which time bilirubin, increased due to jaundice, returns to normal.

The drug Hofitol is suitable for treating the liver, has a gentle effect on the body, improving the condition:

• some organs
• vessels.

Taking the medicine helps lower blood lipid levels. Hofitol works as a means of accelerating the production of bile. Even pregnant women are allowed to take the drug.

Release form

Hofitol tablets are biconvex, brown in color. For sale:

1. in cardboard packages of 12, 30, 60 pieces;
2. in plastic tubes of 60 or 80 pieces.

The oral solution is:

• dark brown syrup,
• turbid,
• with sediment in the form of yellowish particles.

The solution for injection is produced in ampoules of five milligrams.

Composition of the product

Field artichoke extract - active ingredient medicine Hofitol. Inactive ingredients include:

• cornstarch,
• talc,
• carnauba wax,
• gelatin and others.

Pharmacological action of Hofitol

Artichoke is useful plant, which has pronounced properties for:

• removal of bile,
• excess fluid from the body.

Hofitol for the liver, produced on the basis of the extract of this plant:

• reduces the level of carbamide in the blood,
• effectively copes with the hepatoprotective function,
• improves the production of coenzymes Q10 by liver cells, which accelerate metabolic processes in the body.

The medicine helps reduce toxic substances after treatment with antibiotics and other drugs. Hofitol is prescribed to improve metabolism. The drug helps relieve the body of:

• harmful, nitrogen-containing organic substances,
• heavy metals and their salts,
• toxins.

Pharmacodynamics and pharmacokinetics

The action of the complex of vitamins and microelements that are present in artichoke leaves determines pharmacological properties medicinal product. Carrying out observations using the kinetic method and identifying components involved in metabolism is impossible, since therapeutic effect Chophytola is general action all its beneficial substances.

Indications for use of Hofitol

Treatment with Hofitol is carried out together with other medications in complex therapy. It is prescribed in case of diseases such as:

You should avoid drinking alcoholic beverages during treatment with Hofitol.

The drug should be prescribed with caution to patients who have:

• alcohol addiction,
• epileptic disease,
• there is a TBI due to the presence of alcohol in the drug.

On early stages pregnancy, the medicine is prescribed to eliminate the symptoms of early hystosis. During late toxicosis, the drug is taken in combination with other medications. The dosage of the medicine is similar to that of an adult patient.

mirpecheni.ru

Composition and release form

The drug Hofitol is available in the following forms:

1. Hofitol tablets, film-coated. They have the shape of a brown lentil grain. Each tablet contains 200 mg of active ingredient. Active ingredient: dry aqueous extract field artichoke leaves.
2. Hofitol syrup. 1 ml of the substance contains 200 mg of the active ingredient. The capacity of one bottle is 200 ml. For ease of dosing, the drug is available in the form of drops. Active ingredient: thick aqueous extract of field artichoke leaves.
3. Solution for injections Hofitol. 1 ml of Hofitol contains 200 mg of active substance. Package contents: 5 ampoules, 5 ml each. Active ingredient: purified juice extract of fresh artichoke leaves.

Clinical and pharmacological group: herbal medicine with a choleretic and diuretic effect, reducing azotemia.

What is Hofitol used for?

The drug is used in the complex treatment of biliary dyskinesia of the hypokinetic type, chronic non-calculous cholecystitis, chronic hepatitis, liver cirrhosis, chronic nephritis, chronic renal failure.

The drug is used as part of complex therapy various diseases and states:

1. Biliary dyskinesia;
2. Chronic acalculous cholecystitis (inflammation of the gallbladder);
3. Chronic hepatitis;
4. Cirrhosis;
5. Chronic renal failure.
6. Chronic nephritis.

Pharmacological action

Herbal preparation. Pharmacological effect The drug is due to the complex of biologically active substances included in the leaves of the field artichoke.

Cynarin in combination with phenolic acids has a choleretic and hepatoprotective effect. Ascorbic acid, carotene, vitamins B1 and B2, inulin contribute to normalization metabolic processes.

It also has a diuretic effect and enhances the excretion of urea.

Instructions for use

The use of the drug in one form or another is determined by the age of the patient and the nature of the disease.

• Children over 6 years old are prescribed 1-2 tablets 3 times a day before meals. The oral solution, depending on age, is prescribed in a dose ranging from 1/4 to 1/2 the dose used in adults. The course of treatment is 2-3 weeks.
• Adults are prescribed 2-3 tablets or 2.5-5 ml of solution for oral administration 3 times a day before meals. The course of treatment is 2-3 weeks.

The need for repeated courses of therapy with Hofitol is determined individually, depending on the indications.

Contraindications

Hofitol and drug analogues are usually well tolerated, but are contraindicated in some groups of people. Their list is given below:

• patients with cholelithiasis;
• patients with bile duct obstruction;
• patients diagnosed with acute diseases of the kidneys, liver, urinary and biliary tract;
• patients with hypersensitivity to the components of the drug.

The instructions for Hofitol in the form of tablets warn that the drug cannot be prescribed to children under 6 years of age.

Side effects

From the outside digestive system: diarrhea may develop with long-term use drug in high doses. Other: allergic reactions.

Pregnancy and lactation

The use of Hofitol during pregnancy and lactation (breastfeeding) is possible only under the supervision of a physician.

Special instructions

Hofitol should be used with extreme caution in pathologies that could potentially provoke bile duct obstruction, as well as in severe liver pathologies.

The occurrence of abdominal pain and/or diarrhea should be a reason to stop treatment and consult a doctor.

Analogs

Similar drugs with a similar mechanism of action: Allohol, Arnica tincture, Berberine, Hepabene, Convaflavin, Leptandra, Olimethine, Tansy flowers, Choleretic collection, Tanacehol, Phytohepatol No. 2 and No. 3, Flamin, Cholagol, Holemaks, Holos, Holosas, Cavehol, Tsikvalon, Rosehip fruits.

Prices

The average price of HOFITOL in pharmacies (Moscow) is 300 rubles.

Storage conditions and periods

Hofitol should be stored at room temperature. The shelf life of the tablets is 3 years. The shelf life of the oral solution is 4 years. The shelf life of the solution for injection is 2 years.

Conditions for dispensing from pharmacies

Hofitol in the form of tablets and oral solution is approved for use as an over-the-counter product. Hofitol in the form of an injection solution is available with a prescription.

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Composition and release form

Produced in tablets film casing. Also produced:

• Injection solution 20 mg/ml, ampoules 5 ml.
• Oral solution (in the form of a suspension or syrup) in 120 ml dark glass bottles.

The composition of one tablet of Hofitol, which helps the drug with cholecystitis, includes 200 mg of dried aqueous extract of leaves of Cynara scolymus (field artichoke), as well as pregelatized corn starch, talc, magnesium trisilicate, magnesium stearate.

Composition of the oral solution: thick aqueous extract of leaves of Cynara scolymus (field artichoke) at a concentration of 200 mg/ml, ethanol 96%, alcohol tincture orange peel, additives E218 and E216 (methyl parahydroxybenzoate and propylparaben), glycerin, purified water.

Composition of the injection solution: purified extract of Cynara scolymus (field artichoke) leaves at a concentration of 20 mg/ml (100 mg/amp), as well as distilled water in a volume of up to 5 ml.

Pharmacological properties

The main active component of the drug Hofitol, which helps the medicine for liver diseases, is artichoke leaves, rich in a complex of vitamins, microelements and other biologically active substances. Due to the action of phenolic acids in combination with cynarin, Hofitol has a choleretic and hepatoprotective effect.

Inulin, ascorbic acid, B vitamins, in particular B1 and B2, as well as carotene have a normalizing effect on the body's metabolic processes. In addition, important pharmacological effects of the drug, according to reviews of Hofitol, are increased urine excretion and the diuretic effect of the drug.

Solution, drops and tablets Hofitol: what does the medicine help with?

Indications for use include the following diseases:

• dyspeptic disorders, manifested by nausea, flatulence, heartburn, a feeling of heaviness in the epigastric region;
• chronic non-calculous cholecystitis;
• chronic hepatitis;
• dyskinesia of the biliary tract of the hypokinetic type (characterized by slowing and sluggishness of bile outflow);
• cirrhosis;
• chronic nephritis.

What else does Hofitol help with? In combination with others medicines Field artichoke preparations can be used to treat:

• chronic intoxication (salts heavy metals, alkaloids, nitro compounds, hepatotoxic substances);
• uraturia;
• urolithiasis;
• anorexia;
• obesity;
• atherosclerosis.

Contraindications

Hofitol and drug analogues are generally well tolerated, but they are contraindicated in patients with:

• cholelithiasis;
• obstruction of the bile ducts;
• diagnosed with acute diseases of the kidneys, liver, urinary and biliary tract;
• hypersensitivity to the components of the drug Hofitol, which can cause allergies.
• Tablets are not prescribed to children under 6 years of age.

The drug Hofitol: instructions for use

Pills

Patients over the age of twelve are prescribed to take tablets three times a day (before meals), 1-2 pieces at each dose (daily dose from 600 mg to 1.2 g). Treatment usually lasts from 2 to 3 weeks. If necessary, the doctor may prescribe a repeat course.

Hofitol solution: instructions for use

A solution based on artichoke leaf extract is intended for intravenous and intramuscular administration.

Daily dose for patients over fifteen years old - 1-2 ampoules. If necessary, the doctor may increase the dose. The drug is administered parenterally for 8-15 days, after which injection therapy is replaced with an oral solution.

Hofitol drops: instructions for use

The oral solution is shaken and diluted with water before use. A single dose for an adult is 5 ml (1 tsp). Frequency of applications - 3 rubles/day. The duration of treatment depends on the nature and characteristics of the course of the disease.

The use of Hofitol in pediatric practice

In solutions for oral or parenteral use prescribed without age restrictions, tablets for children over six years of age.

Indications for use in children are:

• motility disorders and decreased tone of the gallbladder and its ducts;
• acalculous chronic cholecystitis;
• obesity;
• dyspeptic disorders;
• acute or chronic hepatitis;
• skin diseases(acne in teenagers, psoriasis, etc.);
• chronic nephritis;
• oliguria;
• increased concentration of acetone in the blood, intoxication (salts of heavy metals, nitrates, etc.);
• fatty hepatosis;
• jaundice of newborns;

Children over twelve years of age are prescribed tablets at the same dose as adults. The daily dose of Hofitol tablets for children 6-12 years old is 600 mg (the dose should be divided into three doses).

Chophytol injections are given to children once a day. A single dose for a child under fifteen years of age is 0.25-0.5 ampoules. For adolescents over fifteen years of age, the drug is used in an adult dosage.

Optimal dosage form for newborns are drops. According to the instructions for Hofitol, for newborns it is necessary to measure 5-10 drops of the medicine for each dose. The medicine is given on an empty stomach 3 times a day. Before giving the child Chofitol in drops, the required dose is first dissolved in 5 ml of water.

For adolescents over twelve years of age, 2.5-5 ml of solution is diluted in 1 tbsp. l. water. For children under twelve years of age, take 2-3 (depending on age and indications) milliliters of the drug for the same volume of water. The indicated dose should be taken 3 times a day. 20 minutes before meals.

How to take Hofitol during pregnancy and breastfeeding?

The optimal dosage of tablets during pregnancy is 500 mg/day. The medicine is usually taken for three weeks.

Intramuscular injections of Hofitol are given 1 time per day. using a dose of 10 ml (contents of two ampoules). The drug is administered parenterally for no more than 15 consecutive days. Then, if necessary, your doctor may recommend switching to an oral dosage form.

In the form of an oral solution, Hofitol is taken three times a day, a teaspoon (5 ml). The course of treatment is usually about two weeks. Data on the safety of use of the product during breastfeeding are not provided.

Side effects

As a rule, no side effects occur during treatment with the drug. However, in extremely rare cases, adverse reactions may occur even with obvious indications for Hofitol and the absence of contraindications. First of all, this reaction of the body is caused by long-term use of the drug in high doses. Side effects include allergic reactions and diarrhea.

Analogs

Drugs with a similar mechanism of action:

• Cyclalon.
• Flamin.
• Tansy flowers.
• Phytohepatol.
• Leptandra.
• Holagol.
• Olimethine.
• Allohol.
• Berberine.
• Arnica tincture.
• Rosehip fruits.
• Convaflavin.
• Tanacehol.
• Gepabene.
• Cavehol.
• Choleretic collection.
• Holos.
• Holosas.
• Holemax.
• Artichoke extract.

What is better - Allohol or Hofitol?

Allohol, like Hofitol, is intended for the treatment of pathologies of the liver and biliary tract. Its basis is activated carbon(enterosorbent), bile, garlic bulbs and stinging nettle leaves. The choice in favor of Hofitol is made in situations where the patient is simultaneously diagnosed with liver pathology.

Price, where to buy

In Moscow you can buy Hofitol for 424 rubles. In Kyiv, the product is sold for 98-277 hryvnia. In Minsk, the medicine costs 11-40 Belarusian rubles. In Kazakhstan, its price reaches 4335 tenge (No. 180 TABLE P.O.).

Reviews

If you study the reviews of doctors about Chofitol, you can conclude that the drug is effective for chronic cholecystitis and, in addition, “works” well for liver dysfunction. As a hepatoprotector, the drug is most often used to eliminate the consequences of toxic liver damage (including drug-induced).

Reviews about the treatment of children

The forums also often discuss the feasibility, safety and effectiveness of prescribing Hofitol for children (in particular, for newborns). For older children, the medicine is prescribed for the treatment of diseases of the biliary tract and gall bladder, as well as for the elimination of dyspeptic symptoms, for newborn children - for the treatment of physiological jaundice.

Reviews of Hofitol for children indicate that the drug not only copes with its task very well, but is also very well tolerated by young patients. In addition, the drug is very convenient to use and easy to dose, which is very important when we're talking about about the treatment of infants.

For newborns - reviews are confirmation of this - the drug is prescribed mainly in cases where the child has long period Physiological jaundice persists.

Timely use of Hofitol for newborns helps normalize liver function and biotransformation of insoluble toxic indirect bilirubin into non-toxic direct bilirubin. Mothers of young children note that the child’s blood bilirubin decreased on average by the ninth day of life, and by the end of the second or third week, the symptoms of jaundice completely disappeared.

“I read on the Internet that Hofitol is also prescribed for excessive weight gain during pregnancy and edema. I didn’t have any problems with this before taking the pills, but after I started taking them, my appetite increased, I didn’t notice a diuretic effect, I started gaining weight more. So this doesn’t help everyone. The advantages are that the tablets have a pleasant taste and are small in size.”

“The big PLUS of the Hofitol tablets (in my case) is that it really helps to normalize metabolic processes. That is, they soften, which is important during pregnancy, because the fetus puts pressure on the intestines and problems with stool often arise. Such problems persist over time. There was no problem with taking pills.

The big MINUS of the Hofitol tablets (in my case) is that while I was taking them, my appetite increased, I wanted to eat constantly and, as a result, I gained 3.5 kg in almost a month of taking the tablets.”

“I also drank them during pregnancy, but I didn’t have such an appetite... Perhaps these are the peculiarities of the body’s perception of the medicine”?

“I drank them almost constantly for the first 16 weeks of pregnancy - I had terrible toxicosis, and they were the only thing that saved me.”

"Pregnant women drank artichoke back in ancient Rome! To relieve toxicosis and improve the child’s oxygen supply through the placenta.”

remedy.ucoz.ru

Hophytol is a drug produced by a French pharmaceutical company and is of plant origin: it is an aqueous extract (extract) from the leaves of the field artichoke plant.

This drug restores liver cells, has a choleretic effect, a mild diuretic effect, and helps reduce the level of urea in the blood serum. The drug normalizes the production of enzymes by liver cells, which normalizes cholesterol and fat metabolism. In combination with other medications, it causes the removal of toxins from the body, heavy metals and nitrates.

Chophytol contains microelements, vitamins (C, B1, B2, carotene), biologically active substances in high concentrations, which helps normalize metabolic processes in the body. The drug can be prescribed at any age, treatment can be carried out outside the hospital.

Hofitol has found application in gastroenterology, dermatology, cosmetology, nephrology and obstetric and gynecological practice. The advantages of the drug are: wide range therapeutic action, having a mild hepatoprotective and diuretic effect, practically complete absence adverse reactions, minor toxicity and the possibility of use for a long period without complications.

Already after 2 weeks of taking the medicine, there is an improvement in general well-being, appetite and sleep are normalized. Within a month, taking the drug leads to subjective and objective improvement in 80-90% of patients; In 10-20% of patients, although manifestations of the disease persist, they are much less pronounced. The drug is well tolerated by patients.

Release forms

Hofitol tablets 0.2 g - No. 60 and No. 180 tablets in one package.

Hofitol solution for internal use (in the form of syrup or suspension) 200 ml (1 ml – 200 mg). For newborn children, Hofitol - drops in 200 ml bottles with a dispenser. The solution contains ethanol(in small quantities).

Hofitol solution for injection – 5 ml per ampoule (1 ml – 200 mg), 5 ampoules per package.

Instructions for use of Hofitol

Indications for use

Chronic hepatitis (liver inflammation) of various etiologies: viral, toxic, alcoholic;
initial stage liver cirrhosis;
fatty hepatosis (replacement of liver cells with fat cells);
acalculous chronic cholecystitis (inflammation of the gallbladder);
coma And high level acetone in the blood;
atherosclerosis;
toxicosis during pregnancy (early and late gestosis);
fetoplacental insufficiency, fetal development delay;
intoxication with infectious disease, nitrate poisoning, alcoholic drinks, salts of heavy metals;
reduced motor function(dyskinesia) of the biliary tract and gallbladder;
decreased diuresis (daily amount of urine) in pathologies of the heart and liver;
mild degree CRF (chronic renal failure);
inflammation of the kidneys (nephritis) and urinary tract (pyelonephritis);
obesity and cellulite;
rosacea with demodicosis;
psoriasis;
onychomycosis or fungal disease nails (as part of complex therapy);
dyspeptic manifestations: belching “sour” or “rotten”, bloating, nausea.

Particular caution should be taken when prescribing the drug if bile duct obstruction is not excluded.

Contraindications

Obstruction of the biliary tract;
cholelithiasis;
acute stage gallbladder and liver diseases;
acute stage of kidney and urinary tract diseases;
severe renal and liver failure;
individual intolerance to any component of the drug.

Side effects

Side effects appear after long-term use or taking the drug in high doses:
1. Slight loosening of stool; If you continue to take the drug, diarrhea may develop.
2. Allergic manifestations in the form of urticaria, Quincke's edema (swelling of the skin and subcutaneous tissue).

Treatment with Hofitol

How to take Hofitol?
Depending on the disease, the age of the patient and the form of release of the drug, Hofitol can be used orally in the form of tablets and solution (syrup) and by injection (intramuscular and intravenous). The drug is taken orally before meals; The solution should be shaken before use.

Hofitol does not affect the speed of reaction and concentration, so there is no professional restrictions. Hofitol in the form of drops should be used with caution in persons treated for alcoholism, because The drops contain ethyl alcohol.

Dosage of Hofitol
Adult patients, depending on body weight, are prescribed 1-2 tablets 3 times a day. per day. The dose of Hofitol in the form of a solution for internal use is 3-5 ml (0.5-1 tsp) 3 r. per day. The course of treatment lasts 2-3 weeks. In some cases, the doctor may extend treatment up to 1 month.

Chophytol injection is administered in a dose of 5-10 ml per day, once. If necessary (depending on the severity of the condition), the doctor can increase the dose and number of injections up to 2 times a day. In injections, Hofitol is usually administered for 1-2 weeks, and then switched to forms of release of the drug for internal use.

Hofitol for children

Chophytol is also used in pediatric practice.

Indications for prescribing Chofitol to children:
jaundice of newborns;
hepatitis (acute and chronic);
chronic cholecystitis (non-calculous);
fatty hepatosis;
decline motor activity(dyskinesia) of the gallbladder and biliary tract;
increased levels of acetone in the blood;
cirrhosis;
poisoning (nitrates, salts of heavy metals, etc.);
chronic nephritis;
decreased daily urine output;
chronic renal failure;
skin diseases (psoriasis, acne in adolescents);
obesity;
dyspeptic disorders (bloating, nausea, belching).

Even for newborn children, Hofitol is completely harmless. With proper dosing, the drug does not cause adverse reactions. Jaundice in newborns is significantly reduced, or even completely disappears, after 2-3 days of treatment. After the symptoms disappear, it is recommended to continue taking the drug for another 7-8 days.

The dosage depends on the age of the child. Until the age of 6, Hofitol in tablet form is not used. From 6 years to 12 years, 1 tablet 3 times is prescribed. per day; children over 12 years old - 1-2 tablets 3 rubles. per day.

For babies of the first year of life, Hofitol is used in the form of drops: add 5-10 drops of the solution for internal use to 5 ml of water and take 3 times on an empty stomach. per day.

For children from 6 to 12 years old, Hofitol in drops is prescribed 2-3 ml (or 0.5 tsp or 40-60 drops) with 15 ml of water (on an empty stomach).

Adolescents from 12 to 18 years old – 0.5-1 tsp. with 15 ml of water 3 r. per day.

Hofitol injections for children under 15 years of age: administer 2.5 ml (half an ampoule) or 5 ml 1 r. per day. If it is necessary to increase the dose, treatment is carried out in a hospital under the supervision of a doctor.

The course of treatment with Hofitol usually lasts 2-3 weeks.

Despite the apparent safety of the drug, children should not self-medicate.

Chofitol during pregnancy and lactation

In the early stages of pregnancy, with existing risk factors, Hofitol is used to prevent late gestosis. WITH therapeutic purpose the drug is used as part of complex therapy for the development of late gestosis (preeclampsia, edema, with increased blood pressure, the appearance of protein in the urine). Doses of Hofitol during pregnancy do not differ from dosages for adult patients. If adverse reactions occur, the drug is immediately discontinued. Treatment for a pregnant woman is carried out as prescribed and under the supervision of a doctor.

Clinical data on the results of using Hofitol in breastfeeding No.

Drug interactions

Data about drug interactions Chophytol is not listed in the manufacturer's instructions. There are also no clinical data on drug interactions.

Hofitol's analogs

Synonyms of Chophytol, having the same composition: Cholebil, Artichoke extract, Artichoke leaf extract.

Analogs (drugs with similar effects): Odeston, Heptral, Oxafenamid, Hepaphytol, Rafacholin C, Hepatofit, Artichoke extract hexal, Flamin, Artichol, Holiver.

Herbal medicine with choleretic and diuretic effect, reducing azotemia

Active ingredient

Thick aqueous extract of fresh artichoke leaves (Cynara)

Release form, composition and packaging

◊ Film-coated tablets brown, round, biconvex.

Excipients: magnesium trisilicate - 12 mg, corn starch - 22 mg, talc - 3 mg, magnesium stearate - 3 mg.

Shell composition: gummilac - 1.152 mg, rosin - 1.152 mg, talc - 16.3 mg, gelatin - 0.384 mg, sucrose - 86.146 mg, calcium carbonate - 2.2 mg, dispersed dye (sucrose, yellow, black and brown iron oxides (E172), methyl parahydroxybenzoate (E218 ), ethyl parahydroxybenzoate (E214)) - 2.58 mg, carnauba wax - 0.082 mg, polysorbate 80 - 0.004 mg.

12 pcs. - blisters (5) - cardboard packs.
30 pcs. - blisters (2) - cardboard packs.
30 pcs. - blisters (6) - cardboard packs.
60 pcs. - polypropylene tubes (1) - cardboard packs.
180 pcs. - polypropylene tubes (1) - cardboard packs.

◊ Oral solution dark brown, opaque, with a slight yellowish sediment; There may be some sediment during storage.

Excipients: ethanol - 2.8 g, orange flavor - 2.8 g, glycerol - 0.18 g, methyl parahydroxybenzoate - 0.092 g, propyl parahydroxybenzoate - 0.046 g, purified water - up to 100 ml.

120 ml - dark glass bottles (1) - cardboard packs.

Pharmacological action

Herbal preparation. The pharmacological effect of the drug is due to the complex of biologically active substances contained in the leaves of the field artichoke. Cynarin in combination with phenolic acids has a choleretic and hepatoprotective effect. Carotene, vitamins B1 and B2, and inulin contained in artichokes help normalize metabolic processes.

It also has a diuretic effect and enhances the excretion of urea.

Pharmacokinetics

- chronic nephritis;

- chronic renal failure.

Contraindications

- cholelithiasis;

- obstruction of the bile ducts;

— acute diseases liver, kidneys, biliary and urinary tracts;

— childhood up to 6 years (for tablets);

- hypersensitivity to the components of the drug.

Dosage

For adults Prescribe 2-3 tablets. or 2.5-5 ml of solution for oral administration 3 times a day before meals. The course of treatment is 2-3 weeks.

Children over 6 years old Prescribe 1-2 tablets. 3 times/day before meals. The oral solution, depending on age, is prescribed in a dose ranging from 1/4 to 1/2 the dose used in adults. The course of treatment is 2-3 weeks.

The doctor determines the need for repeated courses of therapy individually.

Side effects

From the digestive system: may develop with long-term use of the drug in high doses.

Others: allergic reactions.

Overdose

Symptoms: Possible increased side effects.

Drug interactions

Drug interactions with Hofitol have not been described.

Chophytol is a plant hepatoprotector. It has a small list of contraindications and side effects, therefore, according to the instructions, it is recommended for children from birth.

Thanks to its diuretic effect, it helps remove toxins and metal salts from the body, enhances the production of liver perforation and urea removal, and improves cholesterol metabolism.

Hofitol for children - the instructions indicate the possibility of use for dyspepsia, intestinal disorders in order to restore liver function, in particular for pregnant women after taking heavy antibiotics.

Release form, composition and packaging

Hofitol is produced in:

• tablets (60-180 pcs);
• injections (100 mg 1 ampoule);
• suspensions (200 ml) in the form of a thick artichoke extract, which is preferable for children;
• syrups (120 ml) in bottles.

The composition of the tablets contains:

• vole artichoke (dried aqueous extract);
• excipients: rosin, talc, sucrose, gelatin, disperse dye, calcium carbonate.

Solutions:

• aqueous extract of field artichoke;
• ethyl alcohol, orange flavor, purified water, methyl parahydroxybenzoate, dietary supplements E218 and E 216.

Injections:

• field artichoke (leaves) purified extract;
• distilled water (5ml).

The packaging form is cardboard. The tablets are placed in polypropylene tubes and blisters.

Pharmacological action

Artichoke, as an active component with dietary supplements (ascorbic acid + vitamins + phenolic acids + carotene) has a choleretic, diuretic, diuretic effect, and has a beneficial effect on the functions:

• liver, increasing the excretion of bile;
• kidneys, increasing the volume of urine excreted.

Thanks to excipients Metabolism in children's liver cells is normalized. When taking Hofitol, a hepatoprotective effect is observed.

Preparation:

• normalizes metabolic processes;
• activates bile secretion and bile formation;
• reduces the level of urea and cholesterol in the blood.

During clinical observations, it was proven that Hofitol actively affects the affected areas, thanks to the active particles in the composition.

Indications for use for children

Hofitol for children is indicated for use in cases of hepatitis, acetonemia against the background of an increased level of acetone in the blood.

Main indications for use:

Hofitol for children is used for:

• insufficient urine output;
• overweight;
• development of inflammation in the kidneys;
• unpleasant symptoms (vomiting, rotten belching, abdominal discomfort);
• poisoning with heavy metals (salt);
• dyspepsia.

According to the instructions, it is prescribed for many gastrointestinal diseases, since it is considered safe and effective drug and is recommended for use by babies from birth.

Instructions for use of Hofitol

Before using Hofitol according to the instructions, it is important to take into account your weight and age.

Recommended dosage form per day:

• tablets – 2-3 pcs;
• syrup for infants up to 1 year, 10 drops 3 times by diluting in 5 ml of warm water;
• capsules for jaundice – 1-2 pcs. 3 times;
• solution for intravenous intramuscular injections – 2.5-3 ml 3 times.

Dosage per day for children, taking into account age:

• 1-3 years – 0.5 tablets 3 times;
• 3-6 years – 1 tablet 2 times;
• 6-12 years - 1 tablet 3 times.

The treatment course is 2-3 weeks. In order to prolong therapy, you should consult your doctor. Injections are prescribed to children for up to 15 days; then, as prescribed by a doctor, they can switch to oral administration of syrup or tablets.

If drops are used, the bottle must be shaken before use to prevent any sediment from entering the body. Drops by dilution in water are the recommended form of taking Hofitol for children from birth.

It is better to give the drug according to the instructions, on an empty stomach up to 3 times a day:

• infants up to 1 year – 7-8 drops with stirring in 5 ml of water;
• 1 year-5 years – 10-20 drops and 15 liters of water;
• 6-12 years - up to 60 drops and 15 ml of water;
• 12-18 years old – 1 tsp. Chophytol + 15 ml of water.

Use of hofitol during pregnancy and lactation

Thanks to its composition, Hofitol has positive impact on female body in general during pregnancy.

Contributes to:

Note! Women are allowed to take Hofitol if there is benefit in relation to possible risks for the fruit it justifies itself.

So, if gestosis is detected at the beginning of pregnancy, the effect will be much higher than the acceptable harm to the child.

Preparation:

• has an antioxidant, hepatoprotective effect;
• minimizes lipid degradation and oxidation;
• creating a protective barrier for the liver;
• enhances the secretion of bile;
• has a diuretic effect;
• reduces cholesterol levels;
• normalizes blood circulation in the placental barrier.

It is possible to prescribe the drug to pregnant women with atherosclerosis and inflammation in urinary tract. According to the instructions, Hofitol can improve overall well-being when drowsiness, dizziness, headache, weakness.

During pregnancy, fluid stagnates excessively in the tissues, which is fraught with complications and serious pathologies. Hofitol normalizes the functions of blood vessels and kidneys, prevents the formation of dropsy and edema.

Attention! Hofitol for children is not an antibiotic, so it is unlikely to be effective for lesions bacterial infection. Additional use of other uroseptics is required.

Doses should not be neglected. The average dosage per day is 50 mg. The course of treatment is 3 weeks. Women during pregnancy can take it in the form of syrup - 1 tsp. or 5 ml 3 times a day with a treatment course of 2 weeks.

The frequency and duration of the course is selected exclusively by the attending physician on an individual basis. Data on how safe the drug is for women during lactation have not been identified.

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Contraindications

Manufacturers claim that Hofitol is a completely safe drug.

When taking tablets, you must follow the dosage, evaluate everything possible contraindications and possible side effects.

Side effects

Rarely, but side effects may occur:

• allergy;
• rash, itching, urticaria similar to burns;
• , loose stools;

If appeared:

• stomach pain;
• vomit;
• pain in the hypochondrium on the right;
• itching, peeling;
• dermatitis;
• digestive disorder, then the drug should be postponed and consult a specialist.

According to patient reviews, Hofitol for children is better tolerated in oral solutions.

Overdose

No cases of overdose have been identified. Rarely, Hofitol solution for children can lead to pathological reactions from the gastrointestinal tract.

Drug interactions

Hofitol contains ethyl alcohol, so it is not advisable to use it in combination with the following drugs:

• cephalosparins (Cefamandole);
• derivatives of 5 Nitroimidazole (Tinidazole, Metronidazole, Ornidazole);
• cytostatics (Procarbazine, Sulfonylurea, Glipizide, Tolbutamide, Disulfiram, Chloramphenicol).

Disulfiram-like reactions, nausea, redness of the skin, sensations of heat, and attacks of tachycardia are possible. In particular there may be adverse reactions when taking Hofitol to children in combination with antifungal agents(Ketoconazole, Griseofulvin).

If other drops also containing alcohol are used, the effect may be reduced and the functions of the central nervous system may be suppressed.

Special instructions

If unpleasant signs appear (nausea, diarrhea, abdominal pain), you should stop taking the drug and consult a doctor.

You should be extremely careful when giving Hofitol to children with diseases of the biliary tract and liver, since inadequate reactions, obstruction or deterioration of the liver are possible.

According to the injection instructions, Hofitol tablets are not capable of slowing down reactions or reducing concentration. The drops contain ethanol, which is something that people who operate vehicles and other machinery need to know.

The drug requires careful use for patients suffering from:

• epileptic seizures;
• pronounced cramps of the transverse muscles;
• chronic alcoholism;
• traumatic brain injury.

When using Hofitol for children (instructions), it is important to consider the dosage and body weight. It is preferable to give infants drops (5-10) by diluting with water (5 ml).

Dose for older children:

• 1-5 years-15 drops;
• 6-12 years– 50-60. The medicine should be given before meals 3 times a day.

Inhalations are not recommended for children under 3 years of age. The herbal medicine (field artichoke) has proven its safety and helps accelerate the excretion of bile, but can cause spasms and choking due to the inability of infants to expectorate excess.

It is best for children under 6 years of age to use the drug in an oral solution. In older children, before inhaling Hofitol, it is advisable to first consult with the treating pediatrician.

Conditions for dispensing from pharmacies

Hofitol tablets are available without a doctor's prescription. However, dosages and expiration dates should not be neglected. You need to read the instructions in the package. When using the solution for children, it is advisable to first consult a doctor.

IV injections should only be given by a specialist, especially when prescribed to children. Incorrect administration of the drug can lead to side effects, allergic reactions.

Injection solutions are sold only with the permission of the attending physician, i.e. by prescription, therefore, when prescribing to children, a preliminary consultation with a pediatrician is required.

Storage conditions and shelf life

The optimal temperature for storage according to the instructions from the manufacturers is +18 +20 degrees.

The expiration date is for:

• tablets - 2 years;
• solution - 3 years;
• syrup - 4 years.

It must be stored in a dry, dark place (instructions), closed to avoid exposure to moisture, light and away from children.

Drug price

The cost varies depending on the dosage and form of the drug.

Approximate price:

• tablets (60 pcs) - 356 rub., 180 pcs — 764 rub.;
• injection solution - 3501 rub. for 120 ml;
• suspension for oral administration - 633 rub. for 120 ml.

Analogs

Almost all analogues of Hofitol for children are similar in composition to the effect and contain herbal components:

1. , release form - tablets. Contains nettle, activated charcoal, bile to provide hepatoprotective, choleretic effects. Release form: syrup, tablets. Similar in action to Hofitol Price 16-30 rub. for 1 package.
2. Holebil for the treatment of colitis, steatosis, cholecystitis, dyskinesia. Contains leaf artichoke. Children can be given capsules up to 2 times a day with food and drink. The treatment course is up to 4 weeks. Price - 46-60 rub.
3. Artichoke, extract with release form in capsules, tablets. Contains dry artichoke extract. Has hepatoprotective, diuretic, intoxicating effects. Helps normalize liver functions and increase the outflow of bile secretions. Indicated for use in children over 6 years of age, 100 mg 3 times a day for hepatitis ( chronic form), urolithiasis, obesity, dyspepsia, impaired motility of the gallbladder. Price - 115-118 rub.
4. How choleretic agent with a release form in tablets (200 mg) of a light shade. Sold in blisters of 50 pieces, it has a selective, antispasmodic effect. Does not affect blood pressure, but perfectly eliminates bile stagnation and prevents cholesterol crystallization. Indicated in the treatment of biliary dyskinesia, cholecystitis, postoperative period on the bile ducts, with constipation, loss of appetite, nausea. The dosage per day should not exceed 1200 mg. Price – 390-490 rub.
5. (pills). Contains methionine, silicon dioxide, carboxymethyl starch, magnesium stearate. Available in tablets or lyophilized for the preparation of solutions. It has antidepressant, antioxidant, choleretic effects. Indicated in the treatment of liver cirrhosis, cholecystitis, non-calculous angiovitis, fatty liver disease, allopathy, liver failure. Attention! It is not recommended for children under 17 years of age. Possible side effects: abdominal pain, nausea, diarrhea, laryngeal swelling, insomnia, dizziness, dry mouth,. Price - 1900 rub.
6. Oxafenamide indicated for diseases: dyskinesia, cholecystitis, cholangitis, chronic hepatitis. It has an antispasmodic and choleretic effect. Price 10-26 rub.
7. Hepatophyte to provide a hypoglycemic effect for problems with the liver and biliary tract. Helps improve antitoxic function, enhance bile secretion, and provide an antispasmodic effect. Indicated for cholangitis, dyskinesia, diabetes mellitus, chronic hepatitis. Not recommended for children under 2 years of age, although cases of overdose have not been identified. Price - 130-150 rub.
8. in tablets (50 mg). Contains immortelle flowers. The drug has an anti-inflammatory, antibacterial, choleretic effect, enhances bile secretion, and increases bilirubin content. Treats cholecystitis, inflammation in the liver tissues, bile ducts. No cases of overdose have been identified. Cost in Russian pharmacies - 50 mg 30 pieces - 100-250 rub.
9. Holyver, contains artichoke, corn, turmeric, bile acids. The drug has an antiseptic effect, helps stimulate intestinal motility, increase bile secretion, remove cholesterol from the blood, eliminate signs of flatulence and heaviness after eating. Recommended for diseases: oliguria, cholecystitis, liver cirrhosis, chronic hepatitis, biliary dyskinesia. Price - 60 rub.
10. Arnica tincture- water decoction. Indicated for the treatment of boils, lumbago rash, cuts, hematomas, pustules on the skin, and also for normalizing cardiovascular activity. Attention! Arnica is a poisonous plant, so it is best to consult your doctor first before taking the tincture. Overdoses are unacceptable to avoid trouble. It is important to consider contraindications. Price - 50-60 rub.
11. Berberine in tablets, active substance- berberine bisulfate. It has a choleretic effect, antispasmodic effect. Indicated when complex treatment chronic hepatitis, cholecystitis, dyskinesia, hypokinetic peptic ulcer. Price - 74 rub. for 30 tablets.
12. capsules, has a choleretic, hepatoprotective effect. Indicated for chronic hepatitis, biliary dyskinesia. Do not give to children under 18 years of age. In case of excessive hypersensitivity to the components of the capsules, the drug is not used in pediatrics. Price - 430-480 rub.
13. Kanvaflavin with antispasmodic and choleretic effects. Absolutely non-toxic, indicated for cholangitis, cholecystitis. Available in bottles, cost: 180-190 rub.
14. Leptandra has a cholinetic, choleretic antiemetic, anti-inflammatory effect. Indicated in the treatment of jaundice, gastralgia, dysentery, diarrhea, biliary colic, inflammation, flatulence, epigastric pain, heartburn in children. Allowed for use by children under 12 years of age. Price – 107-180 rub.
15. Olimethine in capsules. Herbal preparation indicated for hepatitis, anuria, renal failure, urination disorders, hypersensitivity. Olimethine is not sold in pharmacies, so the cost has not yet been revealed.
16. Tanacehol in tablets to provide a choleretic effect. Indicated for cholecystitis, inflammation of the gallbladder, dyskinesia, postcholecystectomy syndrome. Price - 60 rub. per package.
17. Holagol containing turmeric, essential oils. Available in drops, it has a laxative, antispasmodic, and choleretic effect. Indicated for children with cholangitis, biliary colic, liver cirrhosis, epidemic hepatitis, cholecystitis, cholelithiasis. Price – 259-336 rub.

Substitutes that have a similar effect:

• Cyclalone;
• Holemaks;

  The drug promotes:

  • removal of decay products from the biliary tract;
  • normalization of gastrointestinal tract functions;
  • relief from constipation;
  • providing a choleretic effect.

  Allochol contains natural ingredients and is cheaper. What is better - Allohol or Hofitol? It's difficult to answer. The drugs successfully fight bile formation and normalize digestion processes. Hofitol is based on artichoke extract, Allochol is also based on artichoke.

  But, according to patients, Allochol is more effective because it eliminates constipation well and quickly, enhances intestinal motility, eliminates fermentation processes and signs of flatulence.

  Chophytol and Allohol are excellent choleretics, help stimulate the production of bile acids and increase bile secretion.

  Chophytol additionally has a protective effect. Both drugs are bile-containing, so choose the best remedy Only the attending physician will help.

  Hofitol for children is not able to cope with such problems alone, although it has proven effective in treating:

  • psoriasis;
  • hepatitis;
  • dyskinesia;
  • jaundice;
  • constipation

  Noted positive dynamics and improving the condition of the skin. The price of Hofitol is quite reasonable. It's natural herbal composition, does not lead to side effects. Can be given to infants and used by women during pregnancy.

  Editorial office of the newspaper MED-Info
  

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