Nicotinic acid 1%. Instructions for use of nicotinic acid

04.04.2020 -

A nicotinic acid can have a variety of effects on the human body. This allows it to be used for the treatment of many diseases of the circulatory system, stomach and intestines, as well as ailments that develop against the background of atherosclerosis and pellagra.

Participation of the drug in metabolic processes

Nicotinic acid is actively involved in all metabolic processes - protein, fat, and carbohydrate. This happens for the reason that it is part of those enzymes that accelerate oxidative and reduction reactions.

The drug has a particularly active effect on fat metabolism. It helps reduce cholesterol levels in the blood (especially “bad”), which contributes to the formation of plaques in blood vessels. The amount of useful organic compounds that actively participates in metabolic processes can also be increased by nicotinic acid. Indications for use this drug for these reasons the following: most ailments that develop against the background of atherosclerosis, for example, obliterating endarteritis (clogging of the peripheral arteries), ischemic disease of the brain and heart.

Acceleration of blood flow

Among other things, nicotinic acid acts as a dilator on capillaries (small vessels). This promotes blood flow and improves blood supply to various organs. Thus, nicotinic acid can accelerate the process of tissue regeneration, healing of ulcers and wounds. Indications for the use of this drug in this case: many ailments of the intestines and stomach during the period of remission (between exacerbations).

Purpose of the drug

First of all medicine helps in the treatment of pellagra. This disease develops due to a deficiency of nicotinic acid. In this case, metabolic disorders occur, which lead to damage to the skin, resulting in itching, swelling, and redness. Also, with pellagra, the functioning of the intestines, stomach (including the tongue), and brain are disrupted (the result is dementia). In case of insignificant development of the disease and absence severe consequences for central nervous system Nicotinic acid therapy is quite effective.

Treatment of stomach and intestinal diseases

What other pathologies is nicotinic acid used to treat? Indications for use of the drug may be the following - various ailments of the intestines and stomach. Namely:

In all of the above cases, the use of nicotinic acid is permissible only during the period of remission (not during periods of exacerbation). Particular care must be taken when using this medicine when treating peptic ulcer, as it can speed up the process of gastric juice secretion during an exacerbation. As a result, vasodilation is possible, which leads to complications of illnesses and bleeding.

Malabsorption syndrome

There are also diseases of the intestines and stomach that significantly reduce the rate of absorption small intestine food components and nicotinic acid. This pathology It is called “malabsorption syndrome”. It accompanies many diseases that develop in the gastrointestinal tract. With this syndrome, nicotinic acid is introduced into the body intravenously or intramuscularly.

Lack of acid

It happens that a deficiency of nicotinic acid is observed in the body in the case of poor nutrition. A constant menu based on one type of product, the absence of animal proteins, fruits, and vegetables in the diet does not make it possible to saturate the body’s systems and organs with sufficient quantities. In this case, the drug is administered orally or by injection.

Also, a deficiency of nicotinic acid is observed due to severe illnesses of an infectious nature, accompanied by a significant increase in body temperature due to prolonged inflammatory process. In this case, the drug is prescribed only outside the period of exacerbation. In case of chronic liver cirrhosis or hepatitis, nicotinic acid is not used.

Other pathologies

In what other cases is nicotinic acid used? Indications for use may be as follows:

Atherosclerosis and illnesses associated with it - obliterating endarteritis, ischemic heart disease. Consuming acid accelerates cholesterol metabolism, dilates blood vessels, and improves blood supply to tissues and organs.
Trophic ulcers and wounds. Nicotinic acid promotes rapid tissue regeneration and healing.
Restoring the normal functioning of many organs. The drug in this case acts as a vitamin.

Nicotinic acid: side effects

It is permissible to take the drug no more than 6 grams per day. For better perception nicotinic acid should be consumed exclusively after meals and washed down with warm drinks. In the initial stage of therapy with this drug, it is necessary to monitor blood glucose levels. Kidney function should also be monitored to detect acid.

Sometimes the drug is poorly accepted by patients, sometimes redness of the skin and hot flashes are observed. The reason for this is increased synthesis of prostaglandins, disorders in the gastrointestinal tract, hyperuricemia and decreased response to glucose. For this reason, not every body can perceive effective, but large doses of nicotinic acid (from 3 to 5 grams per day).

Toxic effects of the drug

This long-acting drug has rarely caused serious liver toxicity. Therefore, long-term use of nicotinic acid implies control of the functioning of this organ. This effect of the drug on the liver is due to its methylation. Before hepato begins to appear toxic effect nicotinic acid, the level of lipids in the blood sharply decreases.

Hypovitaminosis

Long-term use of nicotinic acid in large quantities leads to the displacement of ascorbic acid from the body. This phenomenon is called hypovitaminosis. To prevent it, additional administration of drugs is considered advisable.

Other deviations

When consuming nicotinic acid, the following deviations may also occur:

Increased acidity of juice in the stomach (exacerbation of ulcers).
Hyperglycemia.
Increased frequency of atrial arrhythmias in patients coronary disease(rare, but possible).
The appearance of stains Brown having a velvety covering on the skin (acanthosis).
Swelling (a fairly rare side effect).

All of these symptoms are quite unstable and disappear after stopping the use of nicotinic acid.

Drug price

How much does nicotinic acid cost? Price in Russian pharmacies ranges from 10.90 rub. for 50 tablets at a dosage of 0.05 grams. The maximum cost is approximately 81 rubles for 10 ampoules of the drug at a dosage of 10 mg/ml.

A nicotinic acid

International nonproprietary name

A nicotinic acid

Dosage form

Solution for injection 1%, 1 ml

Compound

1 ml of solution contains

active substance - nicotinic acid 10 mg,

Excipients: sodium bicarbonate, water for injection.

Description

Transparent, colorless liquid.

Pharmacotherapeutic group

Lipid-lowering drugs. Hypocholesterolemic and hypotriglyceridemic drugs. Nicotinic acid and its derivatives . A nicotinic acid.

Code АТХC10AD02

pharmachologic effect

Pharmacokinetics

Nicotinic acid is rapidly absorbed when administered parenterally. Evenly distributed throughout organs and tissues. Inactivated mainly by methylation and less by conjugation. Partially biotransformed in the liver with the formation of N-methylnicotinamide, methylpyridonecarboxamides, glucuronide and a complex with glycine. The half-life (T1/2) is 45 minutes. It is excreted from the body by the kidneys in unchanged form and in the form of metabolites. Renal clearance depends on the concentration of nicotinic acid in the blood plasma and may decrease at high plasma concentrations. Pharmacodynamics

The structure of nicotinic acid is close to nicotinamide. Nicotinic acid and its amide play a significant role in the life of the body: they are prosthetic groups of enzymes - codehydrase I (diphosphopyridine nucleotide - NAD) and codehydrase II (triphosphopyridine nucleotide - NADP), which are hydrogen carriers and carry out redox processes. Codehydrase II is also involved in phosphate transport.

Nicotinic acid replenishes the deficiency of vitamin PP and has a vasodilating effect. Participates in the regulation of tissue respiration, fat metabolism, reduces general level cholesterol, low-density lipoproteins (especially triglycerides).

Indications for use

prevention and treatment of pellagra (vitaminosis RR)

Included complex therapy: vasospasm of the extremities (obliterating endarteritis, Raynaud's disease), neuritis facial nerve, ischemic disorders cerebral circulation

Directions for use and doses

Nicotinic acid is administered to adults subcutaneously, intramuscularly or slowly intravenously.

For intravenous jet administration a single dose of the drug is diluted in 10 ml of 0.9% sodium chloride solution, administered no less than 5 minutes (no faster than 2 mg of nicotinic acid in 1 minute).

For intravenous drip administration a single dose of the drug is diluted in 100-200 ml of 0.9% sodium chloride solution, the rate of administration is 30-40 drops per minute.

Subcutaneous and intramuscular injections are painful.

For pellagra, a 1% solution of 1 ml is administered intravenously or intramuscularly 1-2 times a day for 10-15 days.

In case of ischemic cerebrovascular accident, 1 ml of 1% solution is administered intravenously (slowly).

For other indications prescribed subcutaneously or intramuscularly at 10 mg (1 ml) once a day for 10-15 days. It is possible to add to the infusion solution: 10 mg (1 ml) of nicotinic acid per 100-200 ml of infusion solution.

Higher doses for intravenous administration: single - 100 mg (10 ml), daily - 300 mg (30 ml).

Side effects

Hyperemia of the face and upper half of the body with a sensation

tingling and burning (in people with hypersensitivity)

Hives, skin rash, itching

Dizziness, feeling of a rush of blood to the head, headache

Orthostatic hypotension, collapse (with rapid intravenous administration)

At long-term use large doses

- dry skin, exfoliative dermatitis

paresthesia

hyperuricemia

hyperpigmentation, hyperkeratosis

decreased glucose tolerance

hyperglycemia

transient increase in aspartate aminotransferase activity,

lactate dehydrogenase, alkaline phosphatase

- asthenia

- pain at the site of subcutaneous and intramuscular injections.

Contraindications

Hypersensitivity to nicotinic acid

Severe forms of arterial hypertension

Atherosclerosis (for intravenous injections)

Peptic ulcer of the stomach and duodenum (at the stage

exacerbation)

Severe liver dysfunction: hepatitis, liver cirrhosis

Recent myocardial infarction

Decompensated diabetes

Gout and hyperuricemia

Pregnancy, lactation period

Children under 18 years of age

Drug interactions

Oral contraception and isoniazid reduce the conversion of tryptophan to niacin and thus may increase the need for niacin.

Nicotinic acid reduces effectiveness and toxicity barbiturates, antituberculosis drugs, sulfonamides. At joint use with sulfonylurea drugs can increase blood glucose levels. Nicotinic acid also reduces the toxicity of neomycin and prevents the decrease in the concentration of cholesterol and high-density lipoproteins induced by it.

Antibiotics may increase skin redness caused by nicotinic acid.

Acetylsalicylic acid reduces the effect of skin redness that occurs under the influence of nicotinic acid.

Lovastatin, pravastatin due to the increased risk of developing adverse reactions It is not recommended to combine with nicotinic acid.

Caution must be exercised when combined with antihypertensive drugs (possible increased hypotensive effect), anticoagulants, acetylsalicylic acid (due to the risk of developing hemorrhages).

The drug potentiates the effect fibrinolytic agents, antispasmodics and cardiac glycosides, toxic effects of alcohol on the liver.

Do not mix with thiamine chloride solution (thiamine is destroyed).

special instructions

Before using the drug, you should consult your doctor.

Since long-term use can lead to fatty liver disease, to prevent the latter, patients’ diets include foods rich in methionine or prescribe methionine and lipoic acid. During treatment it is necessary to monitor liver function. When hypersensitivity to the drug (except when used as a vasodilator) can be replaced with nicotinamide.

Carefully the drug is used for hyperacid gastritis, gastric and duodenal ulcers (outside the acute stage).

The use of the drug may lead to an increase in the need for insulin in patients with diabetes. It is not advisable to use for the correction of dyslipidemia in patients with diabetes mellitus.

It is necessary to regularly monitor glucose due to a possible decrease in glucose tolerance, as well as the level uric acid in the serum due to possible increase as a result of long-term therapy.

Carefully prescribed for glaucoma, bleeding, arterial hypotension, impaired liver and kidney function, liver diseases and a history of impaired liver function, diabetes mellitus, heart rhythm disturbances, migraines, alcohol abuse.

Features of the effect of the drug on the ability to drive vehicle or potentially dangerous mechanisms

Considering the side effects of the drug, caution should be exercised when driving vehicles and moving machinery.

Overdose

Symptoms: gain side effects from the cardiovascular system - arterial hypotension, headache, possible loss of consciousness, dizziness, feeling of a rush of blood to the head.

Treatment: drug withdrawal, detoxification therapy, symptomatic treatment. There is no specific antidote.

Release form and packaging

1 ml in neutral glass ampoules for syringe filling or imported, or sterile ampoules for syringe filling imported, with a break point or break ring.

A label made of label or writing paper is affixed to each ampoule.

5 or 10 ampoules are packed in blister packs made of polyvinyl chloride film and aluminum or imported foil.

Outline packages are placed in boxes made of cardboard or corrugated cardboard.

Approved instructions for medical use in the state and Russian languages. The number of instructions is calculated according to the number of boxes or packages.

Storage conditions

Store in a place protected from light, at a temperature not exceeding 30°C.

Keep out of the reach of children!

Shelf life

Do not use after expiration date.

Conditions for dispensing from pharmacies

On prescription

Manufacturer

Registration Certificate Holder

JSC "Khimpharm", Republic of Kazakhstan

Address of the organization that accepts claims from consumers regarding the quality of products (products) on the territory of the Republic of Kazakhstan

JSC "Khimpharm", Republic of Kazakhstan

Shymkent, st. Rashidova, 81

Phone number 7252 (561342)

Fax number 7252 (561342)

E-mail address [email protected]

Nicotinic acid, injections, what they are prescribed for - this question often arises. The name may be a little misleading, but it is actually a very useful substance. It is actively used in medicine, because the so-called nicotine is a vitamin-like substance that has a beneficial effect on the body.

The benefits of nicotinic acid injections

The drug has many positive properties and its health benefits are impressive. If the body contains nicotine in sufficient quantities, then all organs and systems in it function clearly and correctly. Nicotinic acid, injections, what are they prescribed for? It is used for different purposes - for example, for:

restoration of impaired blood supply in certain areas of the body and brain;
normalization of metabolic processes;
normalization of lipid and carbohydrate metabolism;
relieving detoxification symptoms during;
expansion and strengthening of blood vessels;
control of oxidative processes;
speedy conversion of sugar into energy;
improving bowel function;
memory improvements;
strengthening the immune system;
correction of liver function;
putting the nervous system in order;
stabilization of hormonal levels;
control of hemoglobin synthesis.

Among other things, nicotine improves sleep, stabilizes blood cholesterol levels, takes part in the production of gastric juice and controls certain functions. digestive tract. By understanding what nicotinic acid helps with, and for what purpose the injections are prescribed, you can understand why doctors chose injections. Everything is simple with this - this way the drug penetrates the body faster and is distributed more evenly. In addition, the injections help prevent irritation of the gastric mucosa.

Nicotinic acid injections - indications

The substance can be taken both for treatment and as a prophylactic. Nicotinic acid, injections, what are they prescribed for? One of the most common indications is a deficiency of vitamin PP - pellagra. The drug is effective for diseases of the cardiovascular system. It helps dissolve blood clots. Thanks to this, areas of blood vessels that were blocked open up.

Before you start using nicotinic acid, injections, the instructions for its use must be studied. From it you can find out that the medicine is also prescribed for:

spasms of blood vessels (limbs, brain, kidneys...);
hypoacid gastritis;
ulcers and wounds of various localizations that do not heal within long period time;
complications of diabetes;
liver diseases;
intoxications of various origins.

Nicotinic acid injections for osteochondrosis

This disease occurs when the cartilage in the spinal discs does not receive enough nutrition. As a result, structural changes begin to occur in them, and they become thinner. At the same time, the condition of the bone tissue deteriorates, which becomes deformed and becomes covered with growths in some places. Nicotinic acid, injections, what are they prescribed for, in this case - how can they help? Very fast and efficient!

The injections begin to work almost immediately.

They relieve the main symptoms of osteochondrosis, eliminate dizziness, restore the supply processes to tissues and organs nerve cells, normalize the general condition.
Nicotine affects not only the general physical, but also the mental condition person – the drug gives vigor, lifts vitality, normalizes sleep.
Injections of nicotinic acid, their useful property, accelerates blood microcirculation in soft tissues, due to which pain is reduced, and the regenerating properties of the drug contribute to a significant acceleration of the process of restoration of damaged cartilage tissue, muscles, ligaments, and vascular walls.
Among other things, nicotine can normalize oxygen metabolism and activate oxidative processes.

Nicotinic acid for hair - injections

This substance is often found in hair care products.

Nicotinic acid injections perfectly moisturize curls, enhance their growth, prevent hair loss and fight dandruff.
The effect is due to the vasodilating property of the product, due to which blood flow improves and the hair follicles begin to receive more nutrients.

We have sorted out nicotinic acid, hair injections, and what they are prescribed, but you also need to know how to use the drug correctly. To make your hair healthier and full of strength, use the product for a month. Every day, the contents of one ampoule are applied to clean curls. Treatment can be done by hand or using a syringe without a needle. If 1 ml is not enough, you can use a second ampoule at a time, but no more.

There is no need to wash off the nicotine mask. Immediately after the procedure, goose bumps, a burning sensation, and redness may appear. This phenomenon is normal - it means that the remedy has begun to work. Another thing is headache, itching and rash. Such symptoms indicate individual intolerance and that hair treatment with nicotinic acid should be stopped. Those for whom the therapy is suitable will notice a growth of up to 3 centimeters in their curls within a month.

Nicotinic acid - injections for weight loss

Every body needs nicotinic acid. The optimal amount is up to 20 milligrams per day. You can get it from food - meat and some plant products. A deficiency of the substance has a negative effect on health. This leads to a lack of serotonin, and the body tries to compensate for the deficiencies of the latter by demanding high-calorie foods - cakes, buns, sweets.

How do nicotinic acid injections help you lose weight? Of course, she is not a fat burner. That is, just injections cannot cope with extra pounds, but they can:

speed up processes; force gastric juice develop more actively;
injections contribute to the production of such an important substance.

Simply put, nicotine will discourage the desire to eat unhealthy, fatty, high-calorie foods and help you stick to proper diet and enhance metabolism.

Nicotinic acid, injections - instructions

To get the most from the drug, it must be used correctly. The regimen of nicotinic acid injections must be strictly followed, and it should be selected by a specialist. Standard scheme may not suit everyone. During treatment it is very important to take into account everything individual characteristics body. Otherwise, therapy will not help, or even harm and worsen the condition.

Nicotinic acid - dosage (injections)

The doctor should calculate the dosage and number of necessary injections per day. He also makes the decision to increase or decrease the dose. According to the standard, nicotinic acid, an injection solution, is injected into the body at a rate of 0.1 grams 2 - 3 times a day. If the patient tolerates this treatment well, the dosage may increase to 5 grams. This amount of the drug is usually prescribed for atherosclerosis or serious problems with fat metabolism.

How to give nicotinic acid injections intramuscularly?

The drug nicotinic acid, injections, are given slowly. To ensure that no traces remain on the body after the procedure - irritation, rashes, wounds - doctors use substances such as Sodium Nicotinate or Nicotinamide. There are different methods of administering injections:

intramuscular;
intradermal (it is chosen when it is necessary to compensate for the lack of vitamins);
intravenous (for this method, a 1% solution is diluted in saline).

Nicotinic acid - a painful injection or not?

Bad news, but it's true. The answer to the question whether an injection of nicotinic acid is painful or not is positive. With subcutaneous and intramuscular injection the patient feels the remedy very severe pain, burning. After the procedure, the skin turns red, some people feel feverish, but this is absolutely normal reaction body. It’s worse if the injection has no consequences. In this case, you can suspect the presence of problems with blood circulation.

Nicotinic acid - injections and alcohol - compatibility

Another advantage of nicotine is that it can prevent ethanol poisoning - if you take it 10 - 12 hours before drinking alcohol, but it is undesirable for the substances to be in the body at the same time. Strong drinks neutralize the effect of the medicine, and it turns out that nicotinic acid and intramuscular injections were used in vain. In addition, ethanols increase the risk of adverse reactions. The same best option– give injections a few hours after alcohol enters the body.

Contraindications for nicotinic acid injections

Before starting a course of injections, you need to consult a specialist and find out if there are any contraindications to the use of the drug. Intramuscular injections of nicotinic acid are contraindicated for:

gout;
severe arterial hypertension;
severe form of atherosclerosis;
obviously pronounced violations liver functions;
stomach/duodenal ulcer;
arrhythmias;
sinus tachycardia;
nephrosclerosis;
any inflammation;
allergies to nicotine.

Nicotinic acid first appeared in 1867. At the beginning of the twentieth century, comparing pharmacological properties, was compared with vitamin PP. Since 1938, on the territory Soviet Union, began to be used in the treatment of pellagra, a disease caused by PP deficiency. On Latin called acidum nicotinicum. Refers to group B vitamins number three. Nicotinic acid tablets are used in medicine and cosmetology.

Another name is niacin, in Latin niacinum, in the annotations the name nicotinamide is found. All these are names of one substance that a person needs to carry out redox processes.

Indications for use of nicotinic acid

Nicotinic acid preparations, produced in tablets, affect many organs human body thanks to its properties:

expansion of the vascular bed, stimulation of blood circulation, especially the peripheral part;
impact on metabolic processes - lipid metabolism, cholesterol reduction;
protection of the gastric mucosa;
regulation of liver and pancreas functions;
improving brain nutrition by activating vascular metabolism;
participation in hormonal processes.

The instructions for use indicate the indications for the use of nicotinic acid:

prevention of vitamin PP deficiency, pellagra, manifested mental retardation, loose stools, dermatological skin manifestations;
spicy and chronic hepatitis, cirrhosis;
ischemic stroke;
spasm of peripheral vessels;
cerebral atherosclerosis;
coronary heart disease, conditions after heart attacks;
facial neuritis;
increased blood clotting;
frequent dizziness;
alopecia;
wounds, ulcers with damage to small vessels;
pregnancy, lactation;
trophic, neurological disorders in the lower extremities in diabetes;
weight loss;
stomach diseases – gastritis with low acidity, colitis;
long-term stress.

Watch the video about the importance of nicotinic acid for the body:

Contraindications, features of use

Vitamin PP, available in tablets, is contraindicated in the following cases:

exacerbation of peptic ulcer;
hemorrhagic strokes;
gout;
individual intolerance;
age up to two years.

The annotation indicates special cases when using medications with nicotinic acid should be done with caution:

Do not prescribe high dosages to pregnant women when feeding a baby;
flushes vitamin C from the body, which must be replaced, especially with a long-term treatment regimen;
drink with caution for patients with a history of peptic ulcers or gastritis - nicotine has an irritating effect on the mucous membranes;
therapy for liver diseases and diabetes is carried out under the control of biochemical blood parameters and sugar levels;
The tablets should be taken after meals; the diet should include products with cottage cheese;
It is better to start taking medications with small doses, gradually increasing them, and cancel them in the reverse order.

Types of drugs

The composition of nicotinic acid produced in tablets allows it to be classified as a vitamin supplement:

basic active substance, vitamin PP;
stearic acid, as an auxiliary component;
glucose.

The composition may vary in different release forms, depending on pharmaceutical company engaged in production. The drugs are found in the form:

nicotinamide;
niacin;
nicotinic acid;
Nikonacid.

Nicotine may be included in complex mineral supplements. Reviews about the effectiveness of the drugs agree that there are no differences. The substance helps in any form.

You can buy tablets at pharmacy chains, online stores. The price in pharmacies is always overpriced, because the price includes the rental of retail space, pharmacists' wages, and transportation costs. Purchasing goods in pharmacies is associated with queues and the risk of infection viral infections from the sick. Online stores are more convenient, more mobile, and cheaper. The right site will allow you to save money and purchase quality products.

The well-known world leader in the field of online sales is the iHerb store, which has recently been available in the Russian segment of the Internet.

What are their advantages:

user-friendly interface;
prompt processing of orders around the clock;
prices for additives are 30–50% lower;
free delivery in Russia;
photos, real reviews buyers, evaluations;
certified products from leading global manufacturers.

Nicotinic acid in tablet form has received many customer reviews, which made it possible to compile a list of the best drugs:

Drug dosage regimen

The instructions indicate how to properly take nicotinic acid tablets. The medicine is prescribed to be taken after meals, washed down with cool drinks with neutral acidity - compotes, jelly. Swallowing whole is acceptable, but crushing is allowed. The dosage and treatment regimen are prescribed depending on the goals:

to prevent vitamin deficiency, 25 milligrams per day for adults will benefit, children – half the adult dose;
in the treatment of pellagra, the use of nicotinic acid, available in tablets, at a dosage of 100 mg three times a day, the course is designed for three weeks, helps;
for the treatment of atherosclerosis, taking the substance in a daily dose of 3000 milligrams, divided into three times, is beneficial;
for cardiovascular disorders, a dose of 1000 mg per day helps.

How to drink nicotinic acid tablets correctly when pathological change fat content in the blood, metabolic disorders, the doctor decides. The most commonly used method is when the drug is started with a small dose, 500 milligrams once a day. After a week, the drug is taken twice, and after another week it is increased to three times a day. The doctor determines how long the course of treatment will take. You have to take the vitamin for up to three months.

Cosmetology

Nicotinic acid is used in cosmetology for the treatment and prevention of excessive hair loss. The positive effect is caused by the properties of the active substance:

increased blood circulation in epithelial tissues scalp;
acceleration of metabolic processes in cells;
restoration of damaged hair follicles;
activation of “dormant” bulbs;
strengthening the curl structure;
enhancing healthy hair shine;
enhancing natural hair color, reducing gray hair.

Taken in a dosage of 50 milligrams per day. The course of therapy is three months.

Weight loss

Nicotinic acid is used to combat overweight . Efficiency is associated with the ability to stimulate the release of serotonin, which reduces the need for “fast” carbohydrates. The scheme provides for a gradual increase in dose, the maximum being 1000 milligrams per day. Nicotine is used in combination with diets, increased physical activity. A set of such measures allows you to quickly get rid of extra pounds.

The most common form of release is bottles of 50 mg tablets. How long to store the drug can be found in the instructions. The usual term is 4 years. It is recommended to protect from sunlight.

Side effects, allergic reactions

Various side effects may occur while using nicotinic acid:

redness of the skin associated with increased peripheral circulation;
damage to the mucous membranes of the stomach and intestines;
decline blood pressure;
feeling of heat, rush of blood to the face;
dyspeptic disorders;
numbness of the limbs;
heart rhythm failure;
fatty degeneration of the liver parenchyma;
anorexia.

Allergies cause reactions:

urticaria - rashes in the abdomen, thighs, upper limbs;
Quincke's edema - swelling of the upper respiratory tract;
anaphylactic shock - a sharp expansion of the vascular bed, a drop in pressure, loss of consciousness.

Harm of overdose

Long-term use of high doses of nicotinic acid causes harm. The following symptoms appear:

pain in the epigastric region, nausea, vomiting;
stool disorder;
exacerbation of peptic ulcer;
dizziness;
increased sugar levels;
heart rhythm failure;
the appearance of brown spots on the skin;
blurred vision associated with retinal edema.

The symptoms are not persistent and disappear immediately after discontinuation of the drug. If anyone has experienced other manifestations of an overdose, please share your experience.

Interaction with other drugs

Before starting therapy, you should consult your doctor if you are taking other drugs at the same time. medications due to possible consequences:

incompatible with alcohol - increases the risk of toxic effects on the liver;
antidiabetic drugs lose effectiveness;
side effects of drugs that reduce blood clotting increase;
medications that lower blood pressure increase their effect;
the effect of cardiac drugs and antispasmodics is enhanced;
sulfonamide drugs, the antibiotic neomycin, and sedative barbiturates when taken together cause a toxic reaction.

Nicotinic acid is one of the important elements that regulate the activity of the human body. This vitamin should not be confused with nicotine, these are different substances. But, like any medicine, it has side effects and the risk of overdose. Taking medications in therapeutic doses should begin with consultation with a doctor. Correctly selected dosages have a beneficial effect on the skin, hair, and heart.

Injections of nicotinic acid (nicotine) are prescribed for various diseases. The thing is that it affects the body differently in case of certain ailments. This drug belongs to the vitamin group of medications.

Why are nicotinic acid injections prescribed and their beneficial properties?

Basically, this drug has a positive effect on the body:

normalizes the metabolic process;
restores neural structure;
leads to normal condition blood circulation in certain areas and throughout the body as a whole;
promotes vasodilation, normalization of oxygen absorption and restoration of oxidation processes inside the body;
removes toxins from the body.

Nicotinic acid injections - indications

The drug is used to treat many ailments:

stroke;
poor circulation in the head and limbs;
noise in ears;
pellagra;
poor glucose tolerance;
haemorrhoids;
obesity;
liver diseases;
blurred vision;
with medication, alcohol or occupational intoxication.

The drug is often prescribed for prophylaxis. It helps reduce the possibility of education cancerous tumors in the body and accelerates the breakdown of fats, which has a beneficial effect on their absorption in the body. In addition, it is prescribed to: remove any symptoms of hemorrhoids; treatment of gastritis; improving memory and vision.

Contraindications to the use of nicotinic acid injections

Despite many positive properties, nicotine still has contraindications. Thus, it is not advisable for use by people who have the following ailments: atherosclerosis; stomach ulcer; problems with the duodenum; gout; hepatitis on different stages; diabetes mellitus or simply their body does not interact with the drug.

However, it should be taken with some caution by patients:

with glaucoma and arterial hypotension;
during pregnancy or during feeding.

Side effects

If nicotinic acid injections are prescribed for the treatment of bones, for example, for osteochondrosis, you need to be prepared for some side effects. With short-term use, the main ones are: skin rash and itching, unstable breathing, pain and dizziness. In addition, there is a feeling elevated temperature bodies. Basically, after some time, all symptoms go away on their own.

With long-term use of nicotinic acid in injections, for example, to improve blood circulation, it is imperative to monitor other indicators of the body. The thing is that if the drug enters the body excessively, the following problems may develop:

liver dystrophy;
deterioration of glucose perception;
blood composition disorder.

At the same time, the injections themselves are considered painful.

Consequences of overdose

The dose is prescribed to each person separately, based on personal indicators of the body and age. If the amount of drug for injection is incorrectly calculated, some discomfort. Thus, the most common is considered to be a temporary rush of blood to the upper body and head, itching throughout the body and stomach upset. Symptoms generally go away on their own after some time, or are treated separately.

Application for weight loss

One of the most popular ailments for which injections of the drug nicotinic acid help is excess weight. Many nutritionists and personal trainers prescribe this particular medication because it helps burn fat cells. It is prescribed both in injections and tablets.

Nicotinic acid - injections for health

Vitamin PP is as important for the body as other microelements. Nicotinic acid has an active effect on the body, injections of which are used to treat a huge number of diseases.

Distinctive feature of nicotinic acid

It is not recommended for diabetics, as it negatively affects blood vessels. It should be taken into account that nicotinic acid is better absorbed in tablets; injections are too painful. During injections (after 10-20 minutes), redness begins to be observed, so it is recommended to lie down for a few minutes after the procedure. But even when taken orally, the dose should be increased gradually. Typically this drug is prescribed in an amount of 50-300 mg per day. It removes methyl radicals from the body, so it is taken simultaneously with methionine, vitamin U and choline chloride. And you should include more cottage cheese in your diet. The drug can be obtained at the pharmacy in the form of 50 mg tablets or ampoules of 1 ml of 1% solution.

Spectrum of action

Acid is known not only as a vitamin, it is also famous for its other properties. Thus, it is widely believed that nicotinic acid is useful for lactation. To do this, it is recommended to take the medicine 2 times a day, half an hour before feeding (1-1.5 tablets - it is advisable to find out the dosage from a specialist).

Acid for beauty

Most beauties who strive to grow gorgeous hair sooner or later encounter this pharmaceutical product. Many cosmetologists recommend a course of this drug, because they know that nicotinic acid for the skin is a remedy for its quick recovery. Within a couple of weeks after taking the course of the drug, the skin becomes significantly more radiant and healthy.

Side effects of niacin

Like any other drug, it is bound to have negative effects. They are associated with the release of histamine, and this affects a person as follows: redness of the skin appears, accompanied by itching. Blood pressure may also decrease, dizziness, nausea and diarrhea may appear. And even if all these phenomena were caused by nicotinic acid, the injections do not yet have to be cancelled. Gradually, the body will adapt to the release of histamine and after a while will stop reacting so actively to it. But in some cases, a revision of the dosage and duration of taking the drug is required.

Contraindications for the use of nicotinic acid

First of all, nicotinic acid should be used with caution by those who experience digestive problems - it can, for example, cause an exacerbation of stomach ulcers and inflammation of the duodenum. It is prohibited to prescribe tablets to children under two years of age and parenterally at any age. People suffering from gout, liver and kidney dysfunction, as well as those who have a tendency to bleed, should take nicotinic acid with caution. If nicotinic acid is used for too long, the injections can cause appetite disturbances, vomiting, diarrhea and even liver dysfunction and exacerbation of diabetes.

"Nicotinka." Injections and tablets, their purpose and indications for use

Vitamin PP (nicotinic acid, niacin, nicotinamide) is one of the most important components of the human body. The lack of this vitamin leads to the appearance serious illness- pellagra, which if left untreated can lead to fatal outcome. Pellagra appears depressive state patient, sometimes - diarrhea, vomiting. Often with pellagra, the patient experiences hallucinations, accompanied by confusion of thoughts. Appearance Such signs of the disease should raise concern whether the cause of these symptoms is a lack of nicotinic acid? People often call this component simply “nicotine.” Injections, instructions for their use, consultation, and basic recommendations can only be given by competent employees of medical institutions.

Where is nicotine found naturally?

The main suppliers of vitamin PP (nicotine) are food. Meat, fish, milk, liver contain a lot of nicotinic acid, pectoral muscles Chicken. Plant foods such as tomatoes, cucumbers, and potatoes are also pantries that contain nicotine. Injections, diet food, tablets are prescribed by a doctor if there is insufficient or complete absence this vitamin B food products patient.

The body's needs for nicotine

Need for it vitamin preparation at different people fluctuates depending on age and physiological state. A healthy adult who consumes a normal diet containing nicotine will most likely not need injections because daily norm Such people consume only about 20 mg of the vitamin. Boys have a higher need for nicotine than girls, and women during pregnancy, as well as during breastfeeding, should consume 25 mg of the drug daily.

Nicotine for kids

The daily intake of vitamin PP for six-month-old babies is relatively high. It should not be lower than 6 mg. It is advisable to take into account the composition of food for a child who simply needs nicotine for growth and development. Vitamin PP injections that adults receive can be harmful to children. In addition to the possibility of causing a breakdown with injections nervous activity child, there is a risk of severe burning sensation skin, which can also cause harm to a small organism.

Diagnosis

For the main symptoms of a disease caused by a lack of necotinic acid (nicotine), instructions, as well as recommendations for effective treatment, can be received by the patient only after an accurate confirmation of the diagnosis. When formulating it, the main argument is the quantity, composition and even method of cooking. By analyzing only these components, a diagnosis can be made with certainty. This is due to the good tolerance of culinary processing by vitamin PP. It is not lost when food is frozen, dried, or after exposure to high temperatures. Thus, we need extreme conditions, in which a person will completely stop receiving foods containing the essential vitamin. This fact is of paramount diagnostic importance.

Treatment of diseases caused by nicotine deficiency

After confirming that the cause of the disease is a lack of an element such as nicotine, injections will be most effective method treatment. This is due to the fact that nicotinic acid injections begin to act very quickly without causing irritating effect on gastrointestinal tract, which is typical for tablets. However long-term use The drug, as well as its increased doses, can cause harm to the body. It has been proven that vitamin PP prevents the body from absorbing methionine, and this entails the occurrence of another disease. Therefore, it is recommended that during injections of nicotinic acid, enrich the diet with foods that have high content methionine - cottage cheese, milk, cheese, eggs, fresh fish, soy products and meat.

Nicotinic acid (injections)

Nicotinic acid (injections) is a specific antipellagritic agent. In this regard, the drug is designated "PP-vitamin". Nicotinic acid (injections) when used on initial stages pellagra helps eliminate its phenomena.

In addition to anti-pellagric properties, vitamin PP helps improve carbohydrate metabolism, has a positive effect in mild forms of diabetes, heart disease, liver disease, peptic ulcer disease in duodenum and stomach and enterocolitis. Nicotinic acid (injections) has a vasodilating property and also promotes wound healing.

PP vitamin has a lipoproteinemic effect, reducing the level of lipoproteins in the blood.

Nicotinic acid (injections) helps normalize the functioning of the brain and nervous system. In addition, its positive impact on cardiovascular system, digestion. Nicotinic acid for the skin is one of the main helpers in maintaining it in healthy condition. In addition, the PP vitamin helps ensure normal vision, is involved in improving blood circulation, reducing high blood pressure in the blood due to its vasodilating properties.

Nicotinic acid for lactation is a stimulant. Vitamin PP is involved in vascular blood filling and acceleration of blood circulation in the mammary gland.

The drug is available in ampoules.

For ischemic stroke, PP vitamin is administered intravenously. The dosage is one milliliter of a one percent solution.

Intravenous administration must be done slowly. Rapid intravenous administration of the solution can provoke a significant decrease in blood pressure. Intramuscular and subcutaneous administration of nicotinic acid causes pain.

Taking the drug orally (in the form of powder or tablets), in particular, on an empty stomach or by persons with hypersensitivity, can cause dizziness, redness of the upper body and face, a feeling of a rush of blood to the head, paresthesia (numbness in the extremities), and a nettle rash. As practice shows, these manifestations are eliminated on their own after a certain period of time.

The intravenous drug is contraindicated in persons with hypertension in severe form (with a pronounced persistent increase in blood pressure) and atherosclerosis.

If hypersensitivity to nicotinic acid is detected, it is recommended to replace the drug with nicotinamide. An exception may be when the drug is used as a vasodilator.

In order to increase lactation, the drug is prescribed fifty milligrams orally up to three times a day, ten to fifteen minutes before breastfeeding.

When prescribing during lactation, it is necessary to warn the patient about possible reaction short-term (redness on the face and upper body, feeling of fullness mammary glands, in rare cases itching). The administration of nicotinic acid is recommended in combination with ascorbic acid.

It should be noted that long-term use Vitamin PP in large doses can provoke the development of fatty liver degeneration. In order to prevent this complication You should include foods rich in methionine (an amino acid that is not synthesized in the body) in your diet, or prescribe methionine and other lipotropic (selectively interacting with fats) agents.

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slow hair growth

However, it also has contraindications and can lead to severe redness of the scalp, itching, headaches and dizziness if:

you are prone to allergies, urticaria, and intolerance to certain medications;
you suffer at least sometimes from high blood pressure.

The harm of nicotinic acid can be manifested by the appearance side effects: severe scalp irritation, as well as dizziness and headache. In this case, immediately wash the drug off your head!