Pentalgin antipyretic or not. Green tablets without a prescription Pentalgin: instructions, price and reviews

A combined antispasmodic and anti-inflammatory drug is Pentalgin. Instructions for use explain that the drug is prescribed for pain of various etiologies, at temperatures over time colds. Pentalgin also helps with migraines, toothache, and feverish conditions.

Pharmacological action

The medicine Pentalgin, the instructions for use say this, has antipyretic, analgesic, antispasmodic, and anti-inflammatory effects. The therapeutic effect of the drug is due to the properties of the active components that make up Pentalgin:

• Naproxen belongs to the group of non-steroidal anti-inflammatory drugs and has analgesic, anti-inflammatory and pronounced antipyretic effects, which are associated with the normalization of prostaglandin synthesis.
• Drotaverine acts on the smooth muscles of the biliary tract, gastrointestinal tract, blood vessels and genitourinary system.
• Paracetamol has analgesic and antipyretic properties, which is due to the blockade of COX in the central nervous system and a depressing effect on the centers of thermoregulation and pain.
• Caffeine, which is part of Pentalgin, tones the blood vessels of the brain, causes dilation of the blood vessels of the heart, skeletal muscles and kidneys, helps eliminate drowsiness. As a psychostimulant, caffeine increases the bioavailability of non-narcotic analgesics and increases the permeability of histohematological barriers, which contributes to increased therapeutic effect.
• Pheniramine has a mild sedative and antispasmodic effect and enhances the analgesic effect of the active components of paracetamol and naproxen.

Since some active components penetrate the placental barrier, it is not recommended to use Pentalgin during pregnancy.

Release form and composition

Pentalgin is produced in the form of film-coated tablets. green 2, 6, 10 and 12 pieces in a cell package, 1-2 in a pack. The capsule contains active ingredients: paracetamol, caffeine, naproxen, pheniramine maleate and drotaverine hydrochloride. Additional ingredients: microcrystalline cellulose, croscarmellose sodium, potato starch, hyprolose, citric acid, butylated hydroxytoluene, titanium dioxide, magnesium stearate, talc, indigo carmine, hypromellose, povidone, polysorbate 80, dyes.

Pentalgin tablets: what does the medicine help with?

Main indications for use:

• various types of pain syndromes, for example, radiculitis, articular, muscle pain, during menstruation, neuralgia, algomenorrhea;
• pain due to spasm of smooth muscles caused by chronic cholecystitis, cholelithiasis, renal colic, postcholecystectomy syndrome;
• post-traumatic and postoperative pain, including with inflammatory phenomena;
• colds with fever.

The drug is also used as a cure for toothache and migraines.

Pentalgin: instructions for use

According to the instructions, Pentalgin is taken orally, one tablet at a time. Maximum daily dose should not exceed 4 tablets. The duration of use of Pentalgin depends on the symptoms:

• As an analgesic, Pentalgin, which helps with pain, is taken for up to five days according to the instructions.
• As an antipyretic drug, the drug should not be taken for more than three days. If there is no improvement during this time, it is recommended to consult a doctor to clarify the diagnosis.

Possibility of more long-term use Pentalgin should be discussed with your doctor. In cases where Pentalgin is prescribed during pregnancy, the drug should be taken as soon as possible.

Contraindications

According to the instructions, Pentalgin has a wide range of contraindications, namely:

• Severe renal failure.
• Severe liver failure.
• Increased sensitivity to the components of Pentalgin, from which these tablets can cause allergies.
• Condition after coronary artery bypass surgery.
• Inhibition of bone marrow hematopoiesis.
• Erosive and ulcerative lesions of the gastrointestinal tract in the acute phase.
• Frequent ventricular extrasystole.
• Severe organic diseases cardiovascular system, including acute myocardial infarction.
• Hyperkalemia.
• Age up to 18 years.
• Paroxysmal tachycardia.
• Severe arterial hypertension.
• Combination bronchial asthma, recurrent polyposis of the nose and paranasal sinuses due to intolerance acetylsalicylic acid or other non-steroidal drugs.

• Renal and liver failure light or medium degree gravity.
• Tendency to seizures.
• Cerebrovascular diseases.
• Viral hepatitis.
• History of ulcerative lesions of the gastrointestinal tract.
• Peripheral arterial diseases.
• Glucose-6-phosphate dehydrogenase deficiency.
• Epilepsy.
• Benign hyperbilirubinemia, including Gilbert, Dubin-Johnson and Rotor syndromes.
• Alcoholic liver damage.
• Diabetes mellitus.

Side effects

When treated with Pentalgin, they may develop unwanted effects, For example, allergic reactions, disorders of the nervous, cardiovascular, digestive, genitourinary and hematopoietic systems, as well as sensory organs. This may be accompanied by symptoms such as:

• tremor, headache, sleep problems;
• abnormalities in kidney function;
• dizziness, irregular heartbeat, arrhythmia;
• hearing loss;
• nausea, vomiting, constipation;
• itching, skin rash, urticaria;
• increased blood pressure, pain, erosive and ulcerative disorders of the gastrointestinal tract;
• agranulocytosis, leukopenia, anemia;
• methemoglobinemia, agitation, anxiety;
• angioedema, thrombocytopenia.

Overdose

Do not exceed the doses of Pentalgin indicated in the instructions to avoid overdose, which manifests itself as:

• Increased body temperature.
• Headache.
• Tachycardia.
• Tremors or muscle twitching.
• Increased prothrombin time.
• Gastrointestinal bleeding.
• Increased activity of liver transaminases.
• Paleness of the skin.
• Confusion.
• Lack of appetite.
• Arrhythmia.
• Frequent urination.
• Motor restlessness.
• Excitation.
• Hepatonecrosis.
• Epileptic seizures.
• Nausea, abdominal pain, vomiting.

Symptoms of liver dysfunction may not appear immediately, but 12-48 hours after an overdose. Large doses of Pentalgin can lead to coma, liver failure with progressive encephalopathy, arrhythmia, pancreatitis and death.

Interaction

Long-term combination of Pentalgin with barbiturates, rifampicin, tricyclic antidepressants and ethanol should be avoided to avoid the development of hepatotoxicity.

The simultaneous use of Pentalgin with caffeine-containing drinks and other drugs that stimulate the central nervous system can lead to its overstimulation.

Analogues of the drug Pentalgin

The main analogues are represented by drugs:

• Ibuprofen.
• Paracetamol.
• Pentalgin FS.
• Pentalgin Plus.
• Cardiomagnyl.
• Amizon.
• Analgin.

Pentalgin® is No. 1 in terms of sales volume in monetary terms in the Analgesics category in 2018 in Russia*.

Pentalgin is a combined pain reliever with a unique formula** of five active ingredients to relieve pain, inflammation and spasms.

Thanks to the combination of five components, Pentalgin® has not only analgesic and antispasmodic, but also anti-inflammatory and antipyretic effects. It helps eliminate pain syndromes caused by the most for various reasons(inflammation, neurological diseases, injuries, spasms, etc.), reduce or relieve muscle, joint, menstrual, headache, toothache and other types of pain.

Indications for use

• Pain syndrome of various origins, including pain in the joints, muscles, radiculitis, menstrual pain, neuralgia, dental pain and headaches (including headaches caused by cerebral vasospasm).
• Pain syndrome associated with spasm of smooth muscles, including chronic cholecystitis, cholelithiasis, postcholecystectomy syndrome, renal colic.
• Post-traumatic and postoperative pain syndrome, including those accompanied by inflammation.
• Colds accompanied by fever (as symptomatic therapy).

Pentalgin is the choice of millions of Russians*

The medical drug Pentalgin has wide range therapeutic effects aimed at eliminating pain syndromes of various origins. Being a combined drug, the medication has a pronounced antipyretic, analgesic, antispasmodic and anti-inflammatory effect. Pentalgin has been successfully used as a remedy symptomatic treatment in the treatment of colds accompanied by febrile conditions. Due to the presence of several highly active active elements, there is a wide range of contraindications for use and the risk of developing possible side effects increases.

Dosage form

Pentalgin is available in the form of coated film-coated light green, biconvex, elongated tablets with “PENTALGIN” engraved on one side and a score line on the other.

The drug is packaged in cardboard packs of 2, 4, 6, 10, 12, and 24 tablets, placed in PVC and aluminum blisters.

Description and composition

Dosages active ingredients for 1 tablet:

• – 325 mg;
• caffeine – 50 mg;
• hydrochloride – 40 mg;
• – 100 mg;
• pheniramine maleate – 10 mg.

Auxiliary elements:

• citric acid monohydrate;
• indigo carmine;
• titanium dioxide;
• potato starch;
• green food coloring;
• microcrystalline cellulose;
• yellow food coloring;
• polysorbate 80;
• magnesium stearate;
• talc;
• croscarmellose sodium;
• hyprolose;
• povidone.

Pharmacological group

Pentalgin is a combined medication that has anti-inflammatory, antipyretic, analgesic and antispasmodic effects.

Indications for use

The medical drug Pentalgin is used to eliminate pain syndromes of various origins, and also as a component complex treatment cold pathologies.

for adults

The main indications for prescribing Pentalgin are:

• toothache;
• radiculitis;
• neuralgia;
• headaches;
• muscle and joint pain;
• spasms of smooth muscles accompanied by pain;
• inflammatory processes due to previous injuries or operations, accompanied by pain;
• feverish conditions due to colds (as a means to relieve symptoms).

for children

Application of the product age group under 18 years of age is strictly prohibited.

Pregnant and lactating women are contraindicated in taking Pentalgin.

Contraindications

• worsened ulcers of the gastrointestinal tract;
• severe liver and/or kidney failure;
• bleeding in the digestive tract;
• recent coronary artery bypass surgery;
• pregnancy;
• severe arterial hypertension;
• tachycardia;
• breastfeeding period;
• ventricular extrasystole;
• severe forms of pathologies of the cardiovascular system;
• children under 18 years of age;
• hypersensitivity to active or excipients funds;
• hyperkalemia;
• suppression of hematopoiesis in the bone marrow.

With caution:

• epilepsy;
• convulsions;
• cerebrovascular pathologies;
• viral type hepatitis;
• old age;
• cirrhosis;
• ulcers of the gastrointestinal tract;
• lack of glucose-6-phosphate dehydrogenase in the body.

Applications and dosages

Pentalgin should be taken during or immediately after meals. It is not recommended to break or crush the tablets.

for adults

When using Pentalgin as an antipyretic agent, the duration of the course of therapy should not exceed 3 days. If the medication is used for analgesic purposes, the duration of treatment can last 5 days. Extension of courses is possible only as prescribed by the attending physician.

for children

Children and adolescents under the age of 18 are prohibited from taking Pentalgin.

for pregnant women and during lactation

During pregnancy and lactation period you should not resort to using Pentalgin. If it is absolutely necessary to use the drug during lactation, it is imperative to stop feeding the baby with breast milk.

Side effects

• tremor;
• headache;
• confusion;
• anemia;
• gagging;
• impaired renal function;
• arrhythmia;
• excitability and irritability;
• increased breathing;
• agranulocytosis;
• Quincke's edema;
• ulcerative lesions of the stomach and/or duodenum;
• tinnitus;
• increased blood pressure;
• liver dysfunction;
• dizziness;
• thrombocytopenia;
• dermatitis;
• leukopenia;
• deterioration in concentration;
• sleep disturbance;
• increased intraocular pressure;
• the appearance of an itchy rash.

Interaction with other drugs

The use of barbiturates reduces the therapeutic effectiveness of Pentalgin.

Stimulates action indirect anticoagulants.

Simultaneous use of Pentalgin with tricyclic antidepressants, ethyl alcohol, barbiturates and rifampicin provokes the hepatotoxic effect of the drug.

Also, the combination of the medication with ethyl alcohol increases the likelihood of acute pancreatitis.

Concurrent consumption of drinks and medications containing caffeine can lead to excessive stimulation of the central nervous system.

Reduces diuretic effect, enhances the effect of indirect anticoagulants, increases the concentration of lithium in the blood and increases the degree of toxicity and sulfonamides.

It provokes a weakening of the antiparkinsonian properties of levodopa.

Combining pheniramine with hypnotics, MAO inhibitors and tranquilizers can lead to increased CNS depression.

Special instructions

In case of long-term use of Pentalgin (more than 7 days), the condition of the liver and peripheral blood parameters should be checked.

Caffeine can not only stimulate, but also depress the functioning of the central nervous system. The effect depends directly on the condition of the patient’s body and the type of nervous system.

Violates the reliability of diagnostic results for content uric acid and serum glucose.

During the entire course of treatment with Pentalgin, the consumption of alcoholic beverages should be avoided.

Increases the duration of bleeding.

During therapy, special care should be taken when driving vehicles, working with dangerous machinery and doing activities that require concentration and high reaction speed.

Overdose

Symptoms of Pentalgin poisoning are:

• tachycardia;
• epileptic seizures;
• tremor;
• bleeding in the gastrointestinal tract;
• abdominal pain;
• pale skin;
• increase in prothrombin index;
• hyperthermia;
• frequent urge to urinate;
• complete lack of appetite;
• confusion;
• hyperactivity;
• arrhythmia;
• liver failure;
• acute headache;
• loss of consciousness;
• coma;
• acute form of renal failure.

Acetylcysteine ​​acts as a specific antidote. At the first manifestation of symptoms of poisoning, you should rinse your stomach and take large number sorbents.

Storage conditions

Pentalgin should be stored in a dry place without children having access to the drug.

Shelf life – 2 years.

Analogs

Instead of Pentalgin, the following drugs can be used:

1. Spasmalgon-Effect is complete analogue drug Pentalgin. This is a Bulgarian medicine, produced in tablets, which should not be taken by minors, pregnant patients, or during lactation.
2. Sedalgin-Neo - combination drug, which is a substitute for Pentalgin according to clinical pharmacological group. It is produced in tablets, which are contraindicated for children, pregnant and lactating women. The drug is dispensed strictly according to a doctor's prescription, so self-medication is unacceptable.
3. Sedal-M - Bulgarian drug, which belongs to Pentalgin substitutes in the therapeutic group. The product is sold in tablets, approved for children over 12 years of age, except for pregnant and lactating patients.
4. Solpadeine is a potent combination medication that is a substitute for Pentalgin in the pharmacological group. It is sold in regular and soluble tablets and capsules for oral administration. Solpadeine is prohibited from being prescribed to children under 12 years of age and pregnant women. While taking the medication, breastfeeding should be interrupted.

Drug price

The cost of the medicine is on average 110 rubles. Prices range from 47 to 363 rubles.

When pain occurs, a person looks for a drug that can quickly relieve discomfort and restore full functioning. "Pentalgin" is one of the common analgesics offered in pharmacies. It is important to consider what kind of pain the drug helps with, what effect it has on the human body, and when its use is undesirable.

Release form of the drug and its composition

The drug "Pentalgin" is a film-coated tablet. It is considered a combination drug because it contains several ingredients.

Pentalgin tablets consist of the following active substances (the dosage in one tablet is indicated in brackets, mg):

• paracetamol (325);
• naproxen (100);
• caffeine (50);
• drotaverine hydrochloride (40);
• Pheniramine maleate (10).

In addition to the main active ingredients, the tablet core and the shell itself also include other ingredients. However, they do not have any therapeutic effect. Active substances It is precisely the 5 above-mentioned medicinal compounds that are considered.

The medicine is packaged in cell membranes and cardboard boxes. In each, in addition to the drug itself, there is detailed instructions on the use of the product.

Pharmacological properties of the drug "Pentalgin"

The drug "Pentalgin" - combination remedy, which has an antispasmodic effect and has anti-inflammatory and antipyretic effects. The effect of the drug is determined by the reaction of the substances included in the composition.

Important take a closer look at how each component works medicinal product.

Properties of the drug according to active ingredients

Paracetamol. This active substance helps improve well-being viral infection. The medicine helps eliminate pain and has an antipyretic effect. Paracetamol is used as part complex therapy during treatment infectious pathologies. Pain disappears by blocking the production of cyclooxygenase in the central nervous system, and by influencing thermoregulation centers in the brain.

This is a non-steroidal anti-inflammatory drug that has antipyretic and analgesic effects. The drug also has an effect on the production of cyclooxygenase, due to which unpleasant symptoms disappear and relief occurs. The production of prostaglandins, stimulators of inflammatory processes, is also suppressed.

This component of the drug "Pentalgin" increases the effect of using other drugs. Blood vessels dilate slightly. The person experiences a surge of strength, weakness and drowsiness disappear. Caffeine has a psychostimulating effect, therefore it tones and improves well-being.

Drotaverine hydrochloride. This component helps eliminate spastic pain due to its relaxing effect. Smooth muscle fibers are affected by the medication. That is why the drug helps with pain in internal organs, namely in the bile and bladder, uterus.

This substance, contained in the Pentalgin tablet, has an antihistamine effect and has a mild sedative and relaxing effect. The component increases the activity of paracetamol and helps eliminate swelling and spasms.

Indications for use of the drug

The drug "Pentalgin" is prescribed to relieve pain of various etiologies. The drug is prescribed for the following conditions or diseases:

• painful sensations in the teeth;
• menstrual pain;
• headaches;
• pain in the joints;
• radiculitis;
• neuralgia;
• spastic pain;
• attack of cholelithiasis;
• renal or hepatic colic;
• migraine.

"Pentalgin" for pain is also used in postoperative periods. Often at this time the patient is haunted severe pain, inflammatory processes are possible. The drug greatly facilitates the healing process and improves a person’s well-being.

Pentalgin is also prescribed for fever and colds. These tablets perform auxiliary functions to the main therapy and eliminate fever, muscle pain, and aches.

The drug is dispensed from a network of pharmacies without a prescription. Independent single use of Pentalgin is allowed provided there are no contraindications. If the drug must be taken for a long time, in a course, it is not recommended to do so without the recommendation of the attending physician.

Rules for using the product and dosage

The drug "Pentalgin" is taken entirely in tablet form. It is not chewed, but swallowed whole. You should not split the tablet into several doses - it is important to maintain the integrity of the shell. The medicine should be taken with the required amount drinking water. The duration of treatment can be individual, since much depends on the patient’s well-being and the indications for which the drug is used.

The medicinal drug "Pentalgin" is not recommended for the treatment of children. To reduce negative impact tablets, the drug is prescribed to patients over 12 years of age.

If sudden pain occurs that is not associated with any pathology requiring planned treatment, Pentalgin tablets are taken once, one piece at a time. If you need to take it again, it is important to wait at least 4 hours and only then take the second tablet.

Long-term pain syndromes require systemic use of medication. When treating the musculoskeletal system, the drug is taken for no more than 5 days, one tablet up to three times a day.

To eliminate elevated temperature body and conditions associated with colds, Pentalgin is taken for no more than 3 days. The medication can also be taken 3 times a day, 1 tablet.

Specific dosages can be found by visiting a specialist. Do not exceed daily allowance maximum dose medicine – 4 tablets. When therapy is carried out for a long time, medical monitoring and periodic testing are important.

Contraindications

However, the drug "Pentalgin" cannot always be taken. There are contraindications that must be taken into account.

Pentalgin tablets should not be taken in case of the following phenomena:

• during periods of exacerbation chronic diseases digestive organs;
• stomach and duodenal ulcers;
• hypersensitivity to the components of the drug;
• bronchospasm;
• bronchial asthma;
• nasal polyps;
• kidney and liver damage accompanied by failure;
• arrhythmic manifestations;
• tendency to bleed;
• persistent hypertension;
• severe vascular disorders;
• hyperkalemia;
• surgical interventions on the aorta;
• allergic reactions to aspirin or other drugs from the NSAID category.

It is prohibited to treat children under 12 years of age, since there is no data on how Pentalgin tablets act on young patients.

With caution, painkillers are prescribed to older patients, after 65 years. Negative phenomena may occur when treating persons with epilepsy with Pentalgin, diabetes mellitus And chronic pathologies liver and kidneys.

The use of Pentalgin during pregnancy is prohibited, since the complex composition of the drug can cause damage to the fetus. This medicine is contraindicated for women who are breastfeeding.

Possible adverse reactions

During treatment with Pentalgin tablets, the following side effects may develop:

• itching of the skin and rash;
• nausea and vomiting;
• pain in the epigastric zone;
• stool disorders;
• changes in blood composition;
• decreased appetite;
• hand tremors;
• dizziness;
• insomnia;
• arrhythmic phenomena;
• angioedema shock;
• tinnitus.

If any symptoms appear during treatment negative reactions, it is important to inform your doctor about this. He will be able to select a drug that has a similar effect and does not cause unpleasant symptoms.

Overdose reaction

An overdose of the drug can cause severe conditions requiring medical supervision. If large doses are consumed and help is not provided, death can occur. Signs of overdose appear 5 days after using increased doses.

Symptoms of overdose are:

• abdominal pain;
• nausea and vomiting like “coffee grounds”;
• confusion;
• lethargy and drowsiness;
• increased excitability;
• epilepsy attacks;
• severe liver failure.

In case of an overdose of Pentalgin, symptoms develop gradually. If a person mistakenly takes a large number of tablets, it is necessary to induce vomiting, rinse the stomach, give enterosorbents and immediately contact a medical facility.

"Pentalgin" has an antidote. This is Acetylcysteine. Whether to use it or not is decided after assessing the person’s condition. As a rule, therapy is symptomatic. The introduction of an antidote makes sense if no more than 8 hours have passed since the overdose.

Convulsions, intestinal bleeding, and breathing problems are possible. Most of these conditions require close medical supervision.

Analogues of the drug "Pentalgin"

The drug "Pentalgin" has many analogues, since analgesics and antipyretics are used very often. Instead of this drug, the following medications are used:

• "Pentamialgin";
• "Plivalgin";
• "Pentalffen."

Some of the above-mentioned tablets contain narcotic components and are therefore available from pharmacies only with a prescription. If such a drug was prescribed by a doctor, there will be no problems purchasing it.

By following the manufacturer's instructions and avoiding uncontrolled use of medications, a person can save his life and health.

"Pentalgin", what does this anti-inflammatory help with? medicine? A drug with antispasmodic, analgesic and antipyretic activity is Pentalgin. The instructions for use of the medication indicate that it significantly helps with feverish and painful conditions, and relieves fever during colds.

Varieties and composition

1. Drotaverine hydrochloride.
2. Naproxen.
3. Caffeine.
4. Pheniramine maleate.

Green-colored tablets are coated. Auxiliary components are: cellulose, starch, talc, citric acid, povidone and other substances.

The tablets are packaged in contour cell shells of 2, 6, 10 and 12 pieces in a cardboard box, the drug is accompanied by instructions for use with a detailed description.

Pharmacological properties

The medicine "Pentalgin", which helps for many indications, has 5 active ingredients that determine its action.

The non-steroidal anti-inflammatory substance Naproxen provides antipyretic, analgesic and anti-inflammatory effects. This is achieved due to the ability of the component to inhibit the reproduction of prostaglandins.

Drotaverine hydrochloride has an antispasmodic effect, normalizes the functioning of the smooth muscles of the biliary tract, gastrointestinal, genitourinary and vascular systems.

The presence of paracetamol as an active element allows the medicine to have an analgesic and antipyretic effect. This occurs by blocking cyclooxygenase, an enzyme that promotes the formation inflammatory process, as well as inhibition of pain centers and thermoregulation.

Caffeine tones blood circulation, dilates blood vessels in the brain, heart and other organs. The substance invigorates and eliminates drowsiness. Caffeine shows psychostimulating properties and enhances the effect of other active ingredients.

Due to the inclusion of pheniramine in the composition, antispasmodic and sedative properties are slightly manifested, and the analgesic effect of naproxen and paracetamol increases.

The drug "Pentalgin": what helps

Indications for use include the following diseases and states:

• algodismenorrhea;
• dental or headache;
• migraine;
• neuralgia;
• painful periods;
• high body temperature;
• muscle and joint pain;
• fever during a cold.

What else do Pentalgin tablets help with? The drug is used for pain and spasms during pathologies such as:

• renal colic;
• radiculitis;
• postcholecystectomy syndrome;
• cholecystitis;
• cholelithiasis;
• after operations and injuries.

• Pentalgin tablets: instructions for use

  You need to drink 1 piece after meals. The maximum daily amount should not exceed 4 tablets. The duration of treatment does not depend on symptoms. To reduce fever without medical prescription, tablets are taken for 3 days, to counteract pain - for 5 days.

  If there is no improvement, you should consult a specialist. The dose indicated in the instructions for use for the drug "Pentalgin" cannot be exceeded. In case of overdose, the following are observed: loss of appetite, tachycardia, nausea or vomiting, pallor, arrhythmia, anxiety, tremor, seizures, etc. Symptomatic treatment is necessary.

Contraindications

The instructions for use prohibit taking the medicine "Pentalgin" when:

• individual non-acceptance of the constituent components;
• severe kidney failure;
• hyperkalemia;
• ventricular extrasystole;
• high blood pressure;
• ulcers and erosions of the stomach and intestines;
• aspirin asthma or triad;
• sinus polyps;
• paroxysmal tachycardia;
• myocardial infarction and other complex diseases of the heart and blood vessels;
• after coronary artery bypass surgery;
• internal bleeding;
• inhibition of bone marrow hematopoiesis.

You should not use the medicine "Pentalgin" during pregnancy, children under adulthood, or during lactation. Caution during therapy is necessary for elderly people, as well as those suffering from diabetes, kidney and liver failure. initial stages, arterial pathologies, seizures, hepatitis, stomach ulcers in the past.

Side effects

The drug "Pentalgin", reviews and instructions for use confirm this, can provoke unpleasant effects and disorders in the functioning of various body systems. As a result, the following side effects may occur:

• allergies;
• itching, agitation, nausea or vomiting;
• kidney dysfunction, skin rash;
• heartbeat failure, hearing impairment;
• hives, headache, constipation;
• leukopenia, tremor, angioedema;
• hypertension, anxiety, thrombocytopenia;
• dizziness, agranulocytosis, arrhythmia;
• anemia, sleep disorders, methemoglobinemia.

Price and analogues

"Pentalgin" can be replaced by such drugs as: "", "Ibuprofen", "", "Paracetamol", "Amizon". You can buy tablets for 65 – 170 rubles. The medicine is available without a prescription.

Conditions of release and storage

Pentalgin tablets are sold in pharmacies without a doctor's prescription. The shelf life of the drug is 3 years from the production date; after this period, the drug is not recommended for use.

Must be stored in a dry place, out of reach of children, at a temperature of no more than 25 degrees, avoiding direct contact sun rays on a blister.

Patient opinions

Most often, women praise Pentalgin tablets. Reviews talk about relief during painful periods. The medicine also helps, although only briefly, for toothache or headache. Doctors talk about the effectiveness of the remedy for unpleasant symptoms in the muscles. Their reviews warn that Pentalgin should not be taken long time to prevent, by relieving pain, the development of a complex disease.