How many days to put dikloberl suppositories in gynecology. Dicloberl, solution for intramuscular administration (ampoules)

Pharmacological properties

diclofenac sodium ( sodium salt acetic acid) belongs to the NSAID group of phenylacetic acid derivatives. Has a pronounced anti-inflammatory, analgesic and antipyretic effect, reduces tissue swelling during inflammation; the effects are associated with the ability to block prostaglandin synthesis. Inhibits platelet aggregation caused by ADP and collagen. After rectal administration, the maximum concentration of the drug in the blood plasma is achieved after 30 minutes. Binding to plasma proteins is almost 99%. The half-life is independent of liver and kidney function and is about 2 hours.

Indications

rheumatism, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dystrophic diseases joints, gout, lumbago, neuralgia, myalgia, pain syndrome due to traumatic injury to the musculoskeletal system and soft tissues, primary dysmenorrhea.

Application

the suppository is injected deep into anus, preferably after bowel movement. The dose of the drug depends on the severity of the disease. The recommended dose range for adults and adolescents over 15 years of age is 50-150 mg of diclofenac per day. Daily dose can be divided into 2-3 injections (for this use Dicloberl 50). The duration of use of the drug depends on the effect achieved and the course of the disease.

Contraindications

peptic ulcer, gastrointestinal bleeding, hypersensitivity to diclofenac or other NSAIDs, hematopoietic disorders, asthma, pregnancy, age under 15 years.

Side effects

possible dyspepsia, pain in the epigastric region, headache, dizziness, insomnia, swelling, allergic reactions, nausea, vomiting, diarrhea, anorexia, minor gastrointestinal bleeding, ulcerogenic effects (including bleeding or perforation of the ulcer), hemorrhages, central nervous system disorders (headache, agitation, fatigue, dizziness), hypersensitivity reactions ( skin rash, itching, bullous rashes); a burning sensation and damage to soft tissue at the injection site (sterile abscess, necrosis of subcutaneous fat) are possible. In isolated cases - bloody vomiting, melena, bloody diarrhea, liver damage, edema, hematopoietic disorders (anemia, leukopenia, agranulocytosis, thrombocytopenia), Stevens-Johnson syndrome, Lyell's syndrome, stomatitis, glossitis, esophagitis, exacerbation of chronic inflammatory bowel diseases, constipation, kidney damage, pancreatitis, hemolytic anemia, disturbances of memory, sensitivity and perception (taste, vision, hearing), disorientation, convulsions, feelings of fear, nightmares, tremors, depression, palpitations, chest pain, hypertension, deterioration in certain infectious diseases inflammatory diseases(for example, with necrotizing fasciitis), allergic vasculitis and pulmonitis, severe headache accompanied by nausea, vomiting, fever, stiff neck and confusion (symptoms of aseptic meningitis). Severe hyperergic reactions are possible - swelling of the face, tongue and larynx, bronchospasm, tachycardia, decreased blood pressure, anaphylactic shock.

Special instructions

Use with extreme caution and only under medical supervision for induced porphyrias, abdominal pain when there is a history of peptic ulcer or duodenum, inflammatory bowel diseases (nonspecific ulcerative colitis, Crohn's disease), liver or kidney diseases, hypertension, heart failure, after surgery, in patients with allergic diseases respiratory tract, with increased sensitivity to NSAIDs, with autoimmune diseases(systemic lupus erythematosus, other diseases connective tissue), in elderly people, in the first and second trimesters of pregnancy, during breastfeeding. Dikloberl can affect the ability to control vehicles and potentially dangerous mechanisms; this effect may be enhanced by alcohol consumption. At long-term use Dicloberla needs to regularly monitor liver and kidney function indicators, as well as blood composition and glucose levels. The drug is prescribed with caution to patients with hypertension, liver and kidney diseases, and a history of gastric ulcers. It is not recommended to use the drug during breastfeeding.

Interaction

simultaneous use of Dicloberl with drugs such as digoxin, phenytoin or lithium compounds may increase their levels in the blood plasma. Dicloberl may weaken the effect of diuretics and antihypertensive drugs. The simultaneous use of Dicloberl and potassium-sparing diuretics can lead to hyperkalemia. Dicloberl may weaken the effect of ACE inhibitors. Concomitant use of Dicloberl with ACE inhibitors increases the risk of renal dysfunction. When using Dicloberl with other NSAIDs or with corticosteroids, the risk of side effects from the digestive tract increases. Taking Dicloberl within 24 hours before or after taking methotrexate can lead to an increase in its concentration in the blood plasma and the manifestation toxic effect. No interaction has been identified between Dicloberl and antiplatelet drugs when used simultaneously, however, when using such combinations, it is recommended to constantly monitor blood clotting. Dicloberl may increase the nephrotoxicity of cyclosporine. Medicines containing probenecid may slow down the elimination of Dicloberl. Isolated cases of changes in the concentration of glucose in the blood serum after taking diclofenac sodium, which required dose adjustment of antidiabetic agents, have been described. When taken simultaneously, diclofenac reduces the severity of the effects of furosemide and antihypertensive drugs, increases the concentration of digoxin in the blood plasma. Simultaneous use with potassium-sparing diuretics can lead to the development of hyperkalemia. When administered concomitantly with other NSAIDs or corticosteroids, the risk of gastrointestinal bleeding increases. Combination with methotrexate and cyclosporine is undesirable.

Overdose

is manifested mainly by disturbances on the part of nervous system- headache, dizziness, disorientation and loss of consciousness, as well as abdominal pain, nausea and vomiting, gastrointestinal bleeding, impaired liver and kidney function. Treatment is symptomatic.

Storage conditions

in a place protected from light at temperatures up to 25 ° C.

Photo of the drug

Latin name: Dicloberl

ATX code: M01AB05

Active ingredient: Diclofenac

Analogues: Diclovit, Voltaren, Diclofenac, Rapten Rapid, Rapten Duo

Manufacturer: Berlin-Chemie AG/Menarini Group (Germany)

Manufacturer's website: berlin-chemie.ru

Description is valid on: 27.09.17

Dicloberl and Dicloberl retard are non-steroidal anti-inflammatory drugs for the treatment of rheumatic diseases.

Active ingredient

Diclofenac.

Release form and composition

Enteric-coated tablets containing 50 milligrams of diclofenac sodium. Tablets are sold in blisters in cardboard packages (50 or 100 tablets).

Injection solution containing 75 milligrams of diclofenac sodium. Available in cardboard box five ampoules (each of them three milliliters).

Suppositories are rectal suppositories, the active substance of which is also diclofenac sodium (50 or 100 milligrams). Suppositories are sold in blisters of 5 or 10 suppositories.

Diclofenac retard is a long-acting capsule containing 100 milligrams of diclofenac sodium. Inactive ingredients: oydragit RL 12.5, sucrose, talc, white gelatin, shellac, corn starch, titanium dioxide. Dicloberl retard is sold in blisters of 10, 20 or 50 capsules.

Indications for use

• degenerative and inflammatory diseases of the musculoskeletal system: juvenile chronic, psoriatic, rheumatoid arthritis, neuralgic amyotrophy, ankylosing spondylitis, rheumatism, osteoarthritis, arthritis with Reiter's disease, gouty arthritis(at the moment acute attack for gout, it is advisable to use fast-acting dosage forms);
• as a tocolytic and analgesic - algodismenorrhea, childbirth, inflammation in the pelvis;
• pain syndrome - toothache, migraine, tendinitis, bursitis, sciatica, lumbago, neuralgia, ossalgia, arthralgia, myalgia, radiculitis, postoperative and post-traumatic syndrome (which is accompanied by an inflammatory process), in cancer;
• febrile syndrome in infectious and colds;
• infectious and inflammatory diseases of the ENT organs with pain syndrome - otitis media, tonsillitis, pharyngitis, etc.

Contraindications

• bronchial asthma;
• hematopoietic disorders;
• gastrointestinal bleeding;
• allergic reactions to diclofenac sodium;
• peptic ulcer;
• peptic ulcer stomach or duodenum;
• pregnancy and lactation;
• age up to 15 years.

Instructions for use of Dicloberl (method and dosage)

Solution for injection

Administered intramuscularly. The average daily dosage is 75 milligrams (one ampoule). The maximum permissible daily dose in injections should not exceed 150 milligrams.

Candles

Injected deep into the rectum (only after defecation). The dosage is determined individually by the attending physician (it all depends on the severity of the disease). The daily dose usually varies from 50 to 150 milligrams. It is divided into two or three doses.

Capsules

Take 100 milligrams (one capsule) once a day. If necessary, tablets can also be used.

Pills

Taken orally during meals with a small amount of liquid. The daily dose averages 50-150 mg (in two to three doses). The duration of treatment is determined solely by the treating doctor.

Side effects

The use of Dicloberl can cause the following: side effects:

• From the central nervous system - headache, dizziness, increased fatigue, insomnia, agitation, sensory disturbances, changes in taste, impaired vision and sound perception, a feeling of fear, disorientation, convulsions, depression, nightmares, confusion, stiff neck muscles.
• From the outside digestive system– glossitis, dyspepsia, esophagitis, pancreatitis, liver damage, exacerbation of gastrointestinal diseases, abdominal pain, constipation, diarrhea, nausea, vomiting, minor gastrointestinal bleeding, loss of appetite. Sometimes bloody diarrhea, hematemesis, and melena may occur.
• From the outside cardiovascular system– palpitations, chest pain, arterial hypertension, decreased blood pressure, palpitations, chest pain.
• From the hematopoietic system – agranulocytosis, anemia, leukopenia, thrombocytopenia.
• Allergic reactions - bullous rash, skin rash, burning sensation at the sites of Dicloberl injections, Lyell's syndrome, swelling of the face, larynx and tongue, Stevens-Johnson syndrome, bronchospasm, anaphylactic shock.
• After insertion, suppositories often cause a burning sensation in the anus.

Overdose

In case of an overdose of Dicloberl, the following symptoms occur:

• dizziness;
• headaches;
• hyperventilation;
• clouding of consciousness;
• in children - myoclonic convulsions, nausea, vomiting, abdominal pain, bleeding, liver and kidney dysfunction.

Symptomatic treatment is used to eliminate symptoms.

Analogs

Diclovit, Voltaren, Diclofenac, Rapten Rapid, Rapten Duo.

Pharmacological action

Dicloberl is considered a non-steroidal anti-inflammatory drug, a derivative of phenylacetic acid. The main active ingredient is diclofenac sodium. Due to the inhibition of prostaglandin synthesis, the drug has a pronounced anti-inflammatory effect.

It has analgesic, antipyretic and anti-edematous (at the time of tissue swelling during the inflammatory process) effect. Under the influence of ADP and collagen, it reduces the adhesive properties of platelets.

Special instructions

• Treatment should be started with small doses to ensure there are no adverse reactions. Combination with other NSAIDs increases the risk of side effects.
• Able to mask signs of infection.
• Elderly patients have an increased risk of adverse reactions to LES, especially bleeding and perforation. For these patients, the issue of prescribing combination therapy using gastroprotective agents.
• Careful medical supervision is necessary when prescribing drugs to patients with liver diseases, due to the possible deterioration of their condition.
• During long-term treatment, constant monitoring of liver function and liver enzyme levels is prescribed. If the functioning of the organ is disrupted or the problems worsen, the use of drugs should be stopped immediately.
• The use of diclofenac may be associated with an increased likelihood of thrombotic events (heart attack or stroke).
• At long-term use should be carried out regular monitoring blood test.
• Patients who experience vertigo, blurred vision, or visual impairment during treatment with the drug. nervous activity, drowsiness, fatigue, lethargy, you should not drive a car.
• It is strictly forbidden to combine taking the drug and drinking alcohol. The risk of developing an adverse reaction from the gastrointestinal tract or central nervous system is too high.

During pregnancy and breastfeeding

Contraindicated.

In childhood

Contraindicated in children under 15 years of age.

In old age

It is prescribed with extreme caution, since older people are more prone to developing adverse reactions.

Drug interactions

• The drug increases the level of lithium and digoxin in the blood plasma, increases the toxicity of cyclosporine to the kidneys, and reduces the effectiveness of antihypertensive drugs and diuretics.
• Acetylsalicylic acid reduces the concentration of diclofenac in the blood serum.
• When used simultaneously with potassium-sparing diuretics, drugs increase the risk of developing hyperkalemia. Simultaneous use with glucocorticoids increases the likelihood of bleeding in the gastrointestinal tract.

Conditions for dispensing from pharmacies

Available without a prescription.

Storage conditions and periods

Store in a dry place, protected from light, at a temperature not exceeding 25 °C.

3.60 out of 5 (47 Votes)

As a rule, Dicloberl 100 suppositories are used as an anti-inflammatory, analgesic and antipyretic agent. They are prescribed in many cases, and in gynecology, the doctor often prescribes Dicloberl, as effective remedy for severe pain during menstruation, as well as after gynecological procedures.

But suppositories have their contraindications, so before you start taking them you need to compare all the risks and choose what is a priority.

Many doctors often prescribe a drug that has three important properties, which Dicloberl 100 has:

• good pain relief, relieves painful sensations, has anesthetic properties;
• copes well with high temperatures and heat;
• relieves inflammation and inhibits the development of the inflammatory process.

It is this class of medications that includes the active ingredient of the drug diclofenac, which is a non-steroidal anti-inflammatory drug and forms the basis of Dikloberl.

The range of uses for candles is quite wide:

• sciatica therapy;
• relief of pain in the spine during late pregnancy;
• treatment for cystitis;
• to relieve inflammation in the hip joints;
• to relieve pain after surgery;
• in order to alleviate the condition during gynecological diseases inflammatory in nature.

In gynecology, suppositories are used for severe pain, spasms. Women especially often use Dikloberl suppositories to relieve pain on the first day of menstruation. They are also prescribed by a doctor after gynecological operations.

There are candles Dicloberl 50 and Dicloberl 100.

For example, Dikloberl 50 candles act slower and softer, and 100:

• relieve severe pain;
• remove swelling;
• treat and relieve inflammation of various types.

The unique composition and structured form helps the suppositories quickly dissolve and be absorbed into the mucous walls, thereby quickly and quickly reaching inflammatory foci and stopping their active reproduction.

Types of suppositories by type of administration

Depending on the method of application, candles are divided into 2 types:

1. Vaginal. Intended for women, inserted into the vagina.
2. Rectal. This method is recommended for men. Ladies can also use such suppositories. But for them when they get sick bladder the first option, “female”, is preferable, since absorption of the ingredients will occur much closer to the bladder. This is due to the peculiarities of the anatomy.

If a baby is susceptible to cystitis, the suppository is administered rectally, regardless of the gender of the child. At the same time, the mother has to keep his buttocks squeezed so that the candle does not accidentally slip out of the anus.

In addition, drugs are differentiated according to their inherent medicinal qualities.

Suppositories prescribed for women with cystitis are divided into two main groups. Suppositories are administered rectally (through the anus into the rectum) and vaginally. The latter include pharmacological preparations, inserted deeper into the cervix.

Like any other medicine for inflammation of the bladder, the medicine should be prescribed by the urologist conducting the treatment. In acute cystitis, the duration of suppository placement, depending on the principle of action, ranges from several days to a week.

Candles have positive aspects and disadvantages. Among the advantages are:

• rapid action directly on the localization of the inflammatory process;
• no negative effect on the stomach, which is especially important for recurrent disease;
• rapid restoration of microflora and elimination of infectious agents;
• possibility of combination with other drugs.

There are also disadvantages to suppositories. The medications contain components that irritate the mucous membrane and can cause damage. After inserting the capsule, pain, itching and burning are possible.

Suppositories are used in short courses. Treatment is carried out under the supervision of a urologist. About everyone unwanted effects And unpleasant sensations You should inform your doctor to adjust the dosage or discontinue the drug.

Vaginal suppositories for cystitis

They are especially effective for inflammatory processes that have spread from the bladder to other organs of the reproductive system. Vaginal suppositories for cystitis quickly dissolve in the vagina. Pharmacological components are absorbed into the network of blood vessels and enter the area of ​​the body affected by inflammation.

The suppositories contain medicinal plants, as well as synthetic substances that accelerate tissue regeneration and act as an antiseptic.

Modern vaginal suppositories for the treatment of acute and chronic cystitis are divided into several categories, based on the principle of action:

• antibacterial;
• anti-inflammatory;
• painkillers;
• hematogenous.

Often suppositories combine several types of effects at once. Combined suppositories are in demand for the treatment of chronic cystitis. The most commonly prescribed are: Hexicon, Genferon, Indomethacin, Betadine and Voltaren.

Rectal suppositories for cystitis

The peculiarity of the introduction of suppositories is that they need to be inserted into anal passage. For a greater therapeutic effect, a cleansing enema is given first. Suppositories may not be suitable for patients suffering from hemorrhoids, rectal ulcers, acute forms proctitis.

Rectal anti-inflammatory suppositories for cystitis are suitable for men and women. The positive impact is not limited to bladder treatment alone. The therapeutic effect also appears on the rectum, tissue regeneration and restoration of normal microflora.

Rectal suppositories are preferable for treating men. Use is indicated for prostatitis and urethritis.

The therapeutic effects of the drugs differ. To prevent cystitis, combination drugs are usually used. In the case of acute and chronic inflammation, suppositories are chosen depending on the manifestations of the disease and its symptoms.

During the period of exacerbation, when tableted antispasmodics are insufficiently effective, pain-relieving suppositories are used. If inflammation continues despite drug therapy, suppositories based on NSAIDs and hormones will help. To combat infectious agents use antiviral, antifungal drugs and uroseptics.

The choice of medication due to the presence of contraindications and side effects will be made by the attending physician. Self-therapy negatively affects the general condition of the patient and leads to the development chronic forms diseases.

Painkiller suppositories

Acute inflammation is characterized by the presence pain syndrome, differing in intensity: from simple discomfort to severe cutting and burning. Symptomatic medications in tablet form are not always able to reduce discomfort.

For treatment, the following pain-relieving suppositories are prescribed for cystitis:

• Cefekon is a combination drug that combines analgesic, antipyretic and anti-inflammatory effects. The drug belongs to the NSAID group of drugs, although it is mainly prescribed as an effective pain reliever. Cefekon is given rectally.
• Papaverine is a medicine that relieves spasms and has a hypotensive effect. Suppositories with an anesthetic are safe and are prescribed even to pregnant and breastfeeding women. Suppositories with papaverine are used in preventive measures and as a preventive measure to prevent premature birth caused by cystitis.
• Candles with ichthyol- another combination drug. The main effect is aimed at eliminating pain. The active components of ichthyol are not absorbed into the blood, but directly affect the source of inflammation. Placed rectally. Can be used for hemorrhoids.

For cystitis in men resulting from prostatitis, a course of warming suppositories is recommended. Therapy is carried out exclusively in the absence high temperature body, purulent formations.

Anti-inflammatory suppositories

Medicines mainly belong to the NSAID group. Many of the anti-inflammatory suppositories used for cystitis have a combined effect:

• eliminate infectious factors: viruses, fungi, bacteria;
• relieve inflammation.

In the initial forms of the disease it is usually enough non-steroidal drugs. In case of advanced forms, especially those caused by an acute allergic reaction or age-related changes in the body and aggravated complications (pathologies of the ovaries and appendages), hormonal anti-inflammatory suppositories for cystitis are needed. drug therapy The following suppositories are prescribed:

• Diclovit is an anti-inflammatory agent that combines well with any uroseptics. The use of Diclovit is allowed during the period of antibacterial therapy, as well as during preventive measures to prevent the inflammatory process during surgical intervention, abortions, catheter installation, cystoscopy.
• Longidaza suppositories are successfully used in urology and gynecology. Longidaza suppositories are effective in the treatment of chronic cystitis, aggravated by inflammation of adjacent organs: prostate (in men), urethra and ureters.
• Galavit - used for viral and fungal infections. Preparation combined action, which has a strong anti-inflammatory effect and also has an immunomodulatory effect on the body. We recommend Galavit during the patient’s recovery and as a preventive measure.
• Dikloberl is a drug based on diclofenac sodium. The anti-inflammatory effect is associated with inhibition of prostaglandin synthesis. Dicloberl relieves swelling well and quickly eliminates pain.
• Ketonal in suppositories- tablet forms of the drug are prescribed as a pain reliever. Ketonal suppositories have a combined effect and, in addition to relieving pain, also eliminate the inflammatory process.
• Diclofenac is traditionally used in gynecology and urology as one of the most effective and affordable anti-inflammatory drugs. When using Diclofenac, swelling is relieved and congestion in the pelvic area is eliminated. There is a slight antipyretic result.
• Voltaren - rectal suppositories, combined action. A decrease in pain and inflammation is observed after 2 hours. Voltaren should not be given to pregnant or breastfeeding women.
• Belladonna candles or belladonna extract - main application: proctology and related related violations. The composition contains plant alkaloids that relieve pain, atropine, tannin and belladonna, which block inflammation. Belladonna suppositories are available in several names: Betiol, Anuzol.
• Methyluracil suppositories for cystitis - used during acute inflammation. The process is relieved due to accelerated tissue regeneration, healing of ulcers and injuries. The use of methyluracil suppositories is recommended after surgical operations to eliminate anatomical anomalies in the structure of the urethra, cystitis caused by injuries. The drug is equally effective for men and women.
• Ichthyol candles for cystitis - a combined drug that fights infection and relieves inflammation. There is a slight analgesic effect. The inflammatory process is blocked by improving blood circulation, suppressing bacterial growth and accelerated regeneration of damaged mucosa.
• Phytor suppositories- are available in several versions: with sea buckthorn and propolis. In the first case, suppositories will quickly relieve inflammation and eliminate pain. In the treatment of cystitis, products with propolis are often used. A restorative, regenerative effect is observed.
• Indomethacin suppositories- rectal suppositories with a pronounced anti-inflammatory effect. Additional properties: pain relief and decrease in body temperature. Indomethacin has shown good results during the treatment of chronic congestive inflammatory processes.
• Viburkol is a homeopathic remedy. It is safe and effective. Viburkol suppositories can be used starting from infancy to relieve symptoms of cystitis caused by abnormalities in the structure of the genitourinary system.

Anti-inflammatory suppositories are divided into two categories. The former are classified as drugs of the NSAID group, main task which relieve inflammation. The latter are classified as drugs with combined effects. In addition to eliminating acute processes, they have an additional therapeutic effect: they stimulate immunity and tissue regeneration.

Antibacterial suppositories

Medicines are used in combination therapy for persistent forms of infections with resistance to prescribed tablet drugs. Suppositories are divided into several groups depending on which pathogens they will be effective against:

• Antibacterial suppositories- will help if the infection was caused by pathogenic microflora, pathogenic microbes. The drug is selected taking into account the resistance of bacteria to antibiotics. Antimicrobial suppositories are prescribed only after the results of the culture tank are received.
• Antifungal suppositories- a common causative agent of cystitis is candidiasis and herpes. Conventional antibiotics will not be effective. Antiviral drugs are prescribed.

In urological and gynecological practice to combat pathogenic microflora, viruses and fungi, the following suppositories are prescribed:

• Sintomycin - antibiotic wide range actions. Can be used for some varieties viral infection. Synthomycin suppositories are placed if available purulent infection, the development of abscesses, to prevent general intoxication of the body and combat its consequences.
• Polyoxidonium has proven effective in the treatment of chronic cystitis caused by an allergic reaction, bacterial, viral and fungal infection. Polyoxidonium relieves inflammation. Basic therapeutic effect: powerful immunomodulatory effects. Vaginal and rectal suppositories are available.
• Hexicon is a specialized antiseptic intended for the treatment of infectious inflammatory processes of the urinary system. The drug does not work against viruses, fungi and acid-fast bacteria. Hexicon is prescribed for prophylaxis before childbirth, abortion and elective surgery.
• Urosept or suppositories with palin are suppositories of combined effects. Can be used as monotherapy for uncomplicated cystitis. The advantage of suppositories with palin is the absence of a negative effect on genitourinary system: kidneys, urethral canal. The use of Urosept is recommended for cystitis that provokes pyelonephritis, prostatitis, and urethritis.
• Betadine is a broad-spectrum disinfectant and antiseptic drug. Fights gram-positive and gram-negative bacteria, protozoan viruses, fungi. When using Betadine, there is a high probability of developing an allergic reaction in people intolerant to iodine preparations.
• Depanthol - combination remedy based on chlorhexide. Activity is inhibited and removed from the body: viral and fungal infections, bacteria. Depantol is used for chronic inflammation of the bladder caused by resistant microflora.
• Acylact - the drug is not a uroseptic, but is used in antibacterial therapy. Immunomodulator. It has an inhibitory effect on staphylococci, Escherichia coli and Pseudomonas aeruginosa. Acylact stimulates local immunity and changes the vaginal pH to the acidic side.
• Livarol - antifungal agent. Effectively fights against candidiasis, blocking the ability to reproduce. Livarol is used for prevention and recovery protective functions body after antibacterial therapy.
• Mikozhinaks - combination drug based on 4 antimicrobial components: metronidazole, nystatin, chloramphenicol, descamethasone. Suitable for the treatment of most types of cystitis, regardless of the etiology and catalyst of inflammation. A possible side effect is associated with burning and cutting in the vagina. During pregnancy, the use of Mikozhinax is prohibited.
• Viferon is an immunomodulatory drug with a pronounced antiviral effect. Can be discharged in childhood. Direct reading for the use of Viferon: inflammation caused by chlamydia, enteroviruses, fungi, mycoplasmosis.
• Clotrimazole-Acri- vaginal suppositories with antifungal effects. A course of Clotrimazole-Acri suppositories is intended to combat cystitis caused by trichomoniasis, candidiasis, and genital superinfections.
• Genferon - has a local and systemic effect: stimulates the immune system and suppresses the activity of E. coli. The principle of action of Genferon is based on the use of synthesized recombinant human interferon.
• Macmiror is characterized by low toxicity and high therapeutic efficacy. Helps with inflammation caused by bacteria, viruses, fungi and other pathogenic microorganisms. Macmiror is specifically prescribed for infections caused by intestinal pathogens.
• Bifidumbacterin- pribiotic. The principle of action is based on the activation of natural bacteria that perform protection human body. Strengthening immune forces due to the use of suppositories with lactobacilli inhibits the vital activity of staphylococci, proteus, E. coli and shigella. Bifidumbacterin is prescribed to enhance antibacterial therapy for acute infections, as well as for the prevention of seasonal relapses of cystitis.
• Polygynax - vaginal suppositories. They fight with high effectiveness against bladder infections that arise against the background of vulvitis, vaginitis, and fungi. Polygynax is recommended for use in prenatal prevention. Not suitable for treatment during lactation.
• Nystatin suppositories- antifungal agent. Highly effective against fungi of the Candida family.

When choosing a suppository, the health status of the man or woman and the presence of circumstances affecting therapy (complications, pregnancy, lactation) are taken into account. The urologist will select the appropriate drug based on the results clinical tests and seed tank.

How to insert suppositories correctly

The best rule for using suppositories is to carefully follow the instructions for use. As general recommendations do the following:

• Before administration:
  1. rectal suppositories: make a cleansing microenema;
  2. vaginal: douching.
• Hands must be clean, washed under running water and soap;
• After inserting the suppositories, you need to lie down for at least 40 minutes. This time is enough to give active components absorb into the mucous membrane.

Treatment of the disease

Included in vaginal suppositories medicinal substances absorbed faster than similar oral medications, therefore very popular in the treatment of cystitis in women. Indications for their use include symptoms such as burning when urinating, frequent urge to the toilet, nagging or sharp pain in the abdomen, chills, weakness. IN drug therapy suppositories are used for cystitis in women, painkillers, anti-inflammatory, antibacterial.

Antibacterial

The etiology of cystitis is often bacterial, when the main pathogens are staphylococcus and coli. If the disease is caused by bacteria, then doctors prescribe antibacterial vaginal suppositories that have bactericidal properties. It is recommended to insert suppositories into the vagina for cystitis 1-2 times a day for a week.

The treatment of bladder inflammation must be approached comprehensively. An antibiotic must be included in the treatment regimen, otherwise the disease will very quickly become chronic.

Except, antibacterial drugs Antispasmodic, anti-inflammatory, immunostimulating and herbal remedies are used to treat cystitis.

Quite often, doctors include vaginal and rectal suppositories in their drug therapy regimen.

For cystitis, suppositories with papaverine are prescribed: 1 suppository into the anus in the morning and evening.

They relieve spasm of smooth muscles, eliminate pain and dysuria.

Contraindications to the use of suppositories with papaverine

Suppositories with papaverine should not be prescribed to persons with a number of concomitant diseases:

• glaucoma;
• atherosclerosis;
• rapid heartbeat;
• severe pathologies of the liver and kidneys.

Undesirable effects

Papaverine can cause:

• constipation;
• dizziness;
• skin redness;
• extrasystoles;
• nausea.

The main advantage of suppositories with papaverine is that they can be used to relieve pain due to cystitis in pregnant women.

Suppositories for cystitis are used quite often. Advantages of treatment with suppositories:

• are quickly absorbed and act directly at the site of inflammation;

• enter the bloodstream, bypassing digestive tract and the liver, accordingly, are not destroyed in the acidic gastric environment or as a result of the action of digestive enzymes;
• do not provide systemic action on the body, causing a minimum of side effects.

If you use suppositories, acute cystitis it will go faster. But it is important to understand that suppositories are only an integral part complex therapy inflammation. Suppositories will not completely cure cystitis. Medicines will only alleviate the condition and speed up recovery, and for effective therapy You will need to take antibiotics by mouth. In any case, it is best to consult a doctor before starting treatment.

Prescribed if cystitis occurs with severe pain and is accompanied by increased urine output with a small volume of each portion.

Thanks to medications, it is possible not only to reduce the severe burning sensation, but also to eliminate false urges to urination, but also to prevent complications of the process. It is often recommended for prevention if the disease is chronic, which especially often develops in women during menopause.

The following advantages can be noted:

1. Unlike tablets, suppositories do not affect the functionality of the gastrointestinal tract and do not destroy the beneficial intestinal microflora.
2. In terms of absorption into tissue they are in second place, second only to intravenous injections in speed. Therefore, uncomfortable signs of pathology are eliminated quickly.
3. You can combine medications without limiting yourself to administering just one type of suppository.
4. Therapy is easy to carry out independently, without resorting to the services of medical personnel.
5. If the patient is unable to take the prescribed medications orally, suppositories will help with treatment. This is especially important if you are sick small child or old man who suffered, for example, a stroke.
6. When cystitis is complicated by infection, suppositories will prevent the spread of pathogens to other organs due to their sanitizing properties.

Doctors often prescribe treatment for patients with Dicloberl injections, as this medicine can reduce pain during various diseases. Judging by the reviews of doctors and patients, the medicine is especially good at helping to cope with the following pathologies:

• treatment of osteoarthritis;
• carrying out complex therapy for gout;
• elimination of spondylitis;
• reduction of pain during arthritis and rheumatism;
• eliminating pain from joint damage;
• treatment of primary type dysmenorrhea;
• helping a patient with myalgia and neuralgia;
• getting rid of serious soft tissue injuries accompanied by pain.

It is unacceptable to use this medicinal product without a doctor’s testimony, as it can cause serious harm to the patient’s health.

If the doctor has prescribed the patient to be treated with Dicloberl injections, the injections will be given only intramuscularly. After all, this way the drug is quickly absorbed into the body and has a strong analgesic effect.

An important point is that the injection with Dicloberl should be as deep as possible. The dosage for each patient, regardless of his age, is the same - one ampoule of the drug, which contains 75 milligrams of the main active component.

If the patient is prescribed a long course of treatment, in addition to intramuscular injection drug, they may also prescribe the use of Dicloberl suppositories or tablets. In this case, it will be possible to achieve complete complex action on the body.

Before starting treatment with the drug, it is necessary to familiarize yourself with the possible side effects of the drug, which often make themselves felt if the patient is treated with Dicloberl injections. Not every patient may notice the development of side effects, but each of them still needs to familiarize themselves with this information.

Side effects of Dicloberl, presented in the form of a solution for injection administration of the drug, include:

1. Changes in pressure indicator. When the drug is injected into a muscle, the patient may notice a change in pressure. At the same time, it will jump only in the upward direction. Sometimes patients notice chest pain, as well as the onset of tachycardia.
2. Decrease in hemoglobin level in the bloodstream. In addition to a decrease in this indicator, patients may also notice a decrease in the level of white blood cells. Because of this, their body’s sensitivity to bacterial and fungal infections often increases, since immune system unable to fully control the protection of human health. It is known that leukocytes are protective cells that, as a result of the development of the disease, accumulate in the lesion and begin to actively protect the patient from the development of the disease. And if their number in the body is low, it will become more susceptible to developing dangerous diseases, regardless of their etiology.
3. The appearance of nausea, vomiting or the development of a stomach ulcer. This is only a small part of the side effects that make themselves felt when affected. digestive organs. Therefore, it is better for people with gastrointestinal problems to use the Dicloberl analogue.
4. Possible development of depression. If a patient develops this condition, he may also notice causeless nervous excitability, aggression, and periodic severe headaches. Unfortunately, restore normal mental state the patient will not succeed as long as he is treated with Dicloberl. After this, the patient’s condition will either be completely restored, or he will have to take certain medications to normalize his emotional and mental state.

Thanks to this, you will be able to avoid health problems, as well as significantly reduce the risk re-treatment, only from another disease.

Suppositories in the treatment of cystitis

Suppositories can be used to treat cystitis:

1. antibacterial and antiseptic - to suppress pathogenic flora;
2. anti-inflammatory – to reduce inflammatory processes;
3. antispasmodic - to relieve pain caused by spasm of the smooth muscle tissue of the bladder.

According to the method of administration, suppositories can be:

• rectal;
• vaginal (used in the treatment of women).

What are the contraindications to the use of the medicine?

The basis of treatment for cystitis is antibacterial therapy.

Suppositories Urosept

Urosept suppositories contain pipemidic acid, which causes the death of most gram-negative bacteria, as well as some gram-positive microorganisms.

The highest concentration in the vascular bed and in the urine is observed after 3 hours.

For cystitis, 1 suppository is prescribed in the morning and evening. Course 10 days. Suppositories can be inserted either into the vagina or anus.

Usually the drug is well tolerated; in rare cases, dyspeptic disorders (nausea, vomiting, loose stool) and skin allergies.

You should not insert suppositories if the patient has:

• hypersensitivity to the components of the drug;
• expression of kidney and liver disorders;
• pregnancy;
• age up to 18 years.

During treatment, due to the risk of photosensitivity, exposure to UV rays should be avoided.

When using the drug, it is necessary to increase the amount of fluid you drink, but at the same time you need to control daily diuresis.

It is advisable to drink alkaline mineral water, since when urine is alkalinized, the activity of pipemidic acid increases.

In case of severe illness, it is worth taking antibacterial agents orally.

A synonym for the drug Urosept is Palin.

Hexicon - modern and safe

The active substance of Hexicon suppositories is chlorheskidine biglucanate. It has antibacterial and antiseptic effects on bacteria, Trichomonas, viruses and fungi.

Prescribe 1-2 suppositories in the vagina for 7 days.

Hexicon" for cystitis is prescribed if the patient's cystitis is accompanied by colpitis, thrush and inflammation of the uterus.

The drug is also successfully used to prevent sexually transmitted infections, which, as is known, can also cause inflammation of the bladder.

These are perhaps the only high-quality suppositories that can be used to treat cystitis in pregnant women.

Usually the drug is well tolerated, in rare cases itching in the vagina is possible.

For cystitis, interferon-based suppositories are used to increase immunity, list of the most popular:

• Genferon;
• Viferon;
• Kipferon.

All of them not only improve immunity, but also have an antibacterial effect.

For cystitis, they are prescribed 1 suppository in the morning and evening in the vagina or anus, with the exception of Kipferon, it is inserted only vaginally. Course 10 days.

Contraindications and restrictions

Contraindications to Interferon-based suppositories:

• allergies in the acute stage;
• autoimmune conditions;
• pregnancy first trimester.

Side effects

Treatment with suppositories containing interferon may be accompanied by such side effects as:

• headache;
• myalgia;
• fever;
• increased sweating;
• weakness and fatigue.

Dicloberl injections may not always bring health benefits - in some cases, the drug causes serious harm to the body. That is why, before prescribing the medicine, the patient must undergo full diagnostics, and also hand over necessary tests to identify the course of certain diseases in the body.

According to the instructions for use of the drug with a dosage of 75 mg, the contraindications for the medication are as follows:

• presence of peptic ulcers;
• the patient is allergic to the components of the medicine and the main active component;
• development of ulcers on the walls of the intestines and stomach;
• frequent bleeding in the patient;
• the patient's age is less than 15 years;
• impaired hematopoiesis;
• course of asthma.

If the patient nevertheless decides to use Dicloberl injections if he has contraindications, this can cause severe complications or the development of reactions that are life-threatening for the patient.

Therefore, before using the medicine, it is imperative to consult with a doctor, as well as undergo tests to understand whether the remedy can have a comprehensive healing effect on the body.

It is also prohibited to administer injections during natural feeding of the child. If a doctor prescribes injections to a woman, she needs to completely stop for a while. breast-feeding so as not to harm the health of the baby.

An important criterion when carrying out complex treatment is that each patient must comply with the indications for the use of the medicine, otherwise it may have a negative effect on his health.

An overdose of Dicloberl is also possible. If the doctor gives too high a dose to the patient, he will experience the following: adverse reactions, which you need to urgently get rid of:

• the appearance of seizures;
• loss of consciousness (extremely rare);
• development of strong pressing pain in the head;
• the appearance of nausea, which can turn into vomiting;
• development of severe dizziness;
• development of internal bleeding;
• deterioration of liver function.

In this case, the doctor will need to constantly monitor the patient’s health, since his condition may worsen at any time.

You can buy this remedy at any pharmacy. reasonable price, however, it is unacceptable to take the drug without a doctor’s prescription, otherwise it may have a serious negative effect on the health and general condition of the body, which is already impaired due to an actively developing disease.

Before using Dicloberl, you must read the instructions, since the medication cannot always be combined with medications. For example, giving injections together with taking other non-steroidal drugs may increase side effects and also have a detrimental effect on the functioning of the digestive system. Also, you should not take Methotrexate together with Dicloberl, otherwise it will increase the toxicity of both drugs.

Instructions for use

In practice, gynecologists prescribe suppositories when women complain that in the first days menstrual cycle severe pain is felt.

In most cases, a single dose is enough to relieve spasms, remove aching, nagging pain, and stop the inflammatory process.

Dikloberl - candles that are used in complex treatment diseases. They have an anti-inflammatory and analgesic effect.

Dicloberl is a non-steroidal anti-inflammatory drug that, when administered, reduces fever, relieves swelling and inflammation.

Pharmacological action

Dicloberl is a non-steroidal anti-inflammatory drug. Made from phenylacetic acid. When administered, it reduces fever, relieves swelling and inflammation. Resists diseases that develop in soft tissues. Blocks the spread of the inflammatory process.

Timely use of suppositories for injuries will help avoid swelling and pain during physical activity.

In damaged soft tissues, sensitivity is reduced, and the susceptibility of nerve endings in the injured area is eliminated.

Entering the body, Dicloberl actively inhibits the proliferation of prostaglandins, due to which the body’s resistance process is activated, and the source of inflammation is stopped.

Has an analgesic effect for any source of pain.

Without any residue, it is excreted in urine and feces. After 12 hours, there are no traces of the medication left in the body.

Indications for the use of Dicloberl suppositories

Suppositories are prescribed when systemic disease connective tissues and joints:

• rheumatoid arthritis (including juvenile form);
• Bekhterev's disease;
• spondyloarthritis.

Widely used in gynecology and ENT practice, it is effective against gout and prostatitis during exacerbations. Removes painful sensations for disorders of the nervous system and spinal muscles. Prescribed after surgery and for injuries to relieve pain.

Can be prescribed by a dentist after operations or orthopedic interventions.

Dosage regimen for Dicloberl suppositories

The dosage for an adult patient can range from 50-100 mg depending on the diagnosis. Candles are used 2 times a day: morning and evening.

After relieving acute pain and inflammation, using 1 supp. per day.

Before use, you must empty your bowels to achieve a quick effect. Before administration, hands should be washed with soap to protect the body from the penetration of germs.

Before or after eating?

The use of suppositories does not depend on food intake, because intestinal tract accepts the components of the drug well.

Side effect

Adverse reactions of the body occur when the dosage of the drug is incorrect. These include violations:

• in the gastrointestinal tract: vomiting, bloody discharge in stool, constipation, abdominal pain;
• central nervous system: temporary blurred vision, depression, fear, dizziness, headache, sleep problems;
• in the work of the cardiovascular system: arrhythmia, rapid heartbeat, drop in blood pressure.

The patient may experience allergic reactions, and sometimes changes in blood tests are observed.

Contraindications to the use of Dicloberl suppositories

There are a number of contraindications:

• allergy to diclofenac (this active substance included);
• ulcers in the stomach and duodenum;
• bleeding;
• bronchial asthma;
• children under 15 years of age;
• pregnancy;
• impaired blood circulation.

Special instructions

You should avoid driving and other activities that require concentration due to the possibility of side effects. Do not use the medicine at the same time as taking alcoholic beverages.

Use with caution in patients with diabetes mellitus and with diseases of the thyroid gland.

Use during pregnancy and breastfeeding

Not prescribed for pregnant women and women during lactation. When treating with suppositories, it is recommended to stop breastfeeding.

Use for renal impairment

It is absorbed and has a therapeutic effect if the patient has problems with the kidneys.

Use in children

Used in the treatment of children over 15 years of age.

Overdose

Overdose symptoms:

• severe headache or severe dizziness;
• loss of consciousness;
• convulsions;
• nausea and vomiting;
• impairment of kidney and liver function;
• gastrointestinal bleeding;
• disorientation in space.

If signs are detected, stop taking the medication and seek medical help.

Drug interactions

• when using phenytoin or lithium with Dicloberl, their composition in the blood will increase;
• if you take diuretics or drugs to reduce hypertension, then the effect of using Dicloberl is reduced;
• when taking diuretics with potassium, their concentration in the patient’s blood increases;
• using the drug together with inhibitors can cause kidney problems;
• joint use of other non-steroidal drugs will increase side effects on the gastrointestinal tract;
• parallel use of methotrexate along with suppositories increases the toxicity of the former;
• combination of antiplatelet drugs with medicine requires constant monitoring of changes in blood tests;
• taking the drug together with cyclosporine increases the level of toxicity;
• probenecid drugs slow down the elimination of Dicloberl and lead to adverse reactions;

Indications for use:
Rheumatic diseases (rheumatoid arthritis, rheumatism, osteoarthritis),
ankylosing spondylitis,
gout,
dystrophic joint diseases,
pain due to injuries of the musculoskeletal system and/or soft tissues,
neuralgia,
myalgia,
primary dysmenorrhea.

Pharmacological action:
Dicloberl is a non-steroidal anti-inflammatory drug, a derivative of phenylacetic acid. The active substance of the product is diclofenac sodium. It has a pronounced anti-inflammatory effect due to inhibition of prostaglandin synthesis. It has an antipyretic, analgesic and anti-edematous (tissue swelling due to inflammation) effect. Reduces the adhesive properties of platelets under the influence of collagen and ADP.

With parenteral (intramuscular) administration, Cmax in blood plasma is observed after 10-20 minutes. After oral administration, diclofenac is completely absorbed from the intestine. Cmax in blood plasma is observed after 1-16 hours (according to average data - after 2-3 hours). After absorption from the intestine, first-pass metabolism occurs due to the primary passage through the liver. 35-70% enters the posthepatic circulation active substance. After administration of the suppository into the rectum, Cmax in blood plasma is observed after 30 minutes.

Approximately 30% of diclofenac is metabolized. Metabolic products are eliminated by the intestines. Inactive metabolites obtained through conjugation and hydroxylation by hepatocytes are eliminated by the kidneys. The half-life is 2 hours and is independent of renal and liver function. 99% of the product is bound by blood proteins.

Dicloberl method of application and dose:
Dicloberl 75 for parenteral administration is injected into the gluteal muscle (deep intramuscularly). Daily dose – 75 mg (1 ampoule). The maximum daily dose is no more than 150 mg. If long-term treatment with dikloberl is necessary, oral or rectal forms are prescribed.

Dicloberl 50 tablets are taken orally during meals (to eliminate the irritating effect on the gastric mucosa), with a small amount of liquid. Do not chew. The daily dose is 50-150 mg, divided into 2-3 doses. The duration of therapy is determined by the doctor individually.

Dicloberl retard capsules are taken once a day (100 mg). If it is necessary to increase the dose, use Dicloberl 50 tablets.

Dicloberl 50 suppositories are injected deep into the rectum after defecation. The dose is determined individually by the doctor depending on the severity of the disease. Typically, the daily dose should be in the range of 50-150 mg (for adults and patients childhood over 15 years old). The daily dose is administered in 2-3 doses.

Dicloberl contraindications:
allergic reactions to diclofenac (or other products from the group of non-steroidal anti-inflammatory drugs),
peptic ulcer of the stomach or duodenum,
peptic ulcer,
gastrointestinal bleeding,
hematopoietic disorders,
bronchial asthma,
age less than 15 years.

Dicloberl side effects actions:
From the gastrointestinal tract: dyspepsia, glossitis, esophagitis, liver damage, exacerbation gastrointestinal diseases, pancreatitis, constipation, abdominal pain, vomiting, diarrhea, nausea, loss of appetite, minor gastrointestinal bleeding is possible; in patients with gastrointestinal diseases, bleeding and ulcer perforation may occur. In isolated cases - melena, bloody vomiting, bloody diarrhea.
From the central nervous system: dizziness, headache, insomnia, high fatigue, agitation, changes in taste, sensory disturbances, changes in the perception of sounds, visual disturbances, disorientation, a feeling of fear, convulsions, nightmares, depression, tremors, stiffness of the neck muscles (aseptic meningitis), confusion.

Allergic reactions: skin rash, bullous rashes, itching, burning sensation at the injection site, sterile abscess at the injection site, Lyell's syndrome, necrosis of subcutaneous fat at the injection site, swelling of the tongue, face and larynx, Stevens-Johnson syndrome, anaphylactic shock, bronchospasm.

From the blood system: thrombocytopenia, anemia, agranulocytosis, leukopenia.

From the cardiovascular system: chest pain, palpitations, decreased blood pressure, arterial hypertension.
Other: possible deterioration general condition with necrotizing fasciitis, pulmonitis, allergic vasculitis.

Pregnancy:
Dicloberl is contraindicated for pregnant women and breastfeeding women.

Overdose:
Exceeding the dose requires symptomatic treatment. Dizziness, headache, loss of consciousness, disorientation, myoclonic convulsions in children, vomiting, nausea, abdominal pain, impaired renal and hepatic function, and gastrointestinal bleeding are possible.

Use with other medications:
Taking dicloberl while using phenytoin, digoxin, and lithium products increases the level of these substances in the blood plasma. When taken together with diuretics and drugs to reduce hypertension, the subsequent effectiveness is reduced. When combined with potassium-sparing diuretics, an increase in potassium concentration in the blood is observed.

Combination with angiotensin-converting factor inhibitors can provoke renal dysfunction. In combination with glucocorticosteroids and other non-steroidal anti-inflammatory drugs, they increase side effects on the gastrointestinal tract.

When used one day before or after methotrexate, an increase in the concentration of methotrexate and an increase in its toxic effects are observed. When used in combination with antiplatelet agents, medical monitoring of the blood coagulation system is necessary (although no interaction has yet been detected).

In combination with cyclosporine, the toxic effect of cyclosporine is enhanced. Products containing probenecid slow down the elimination of diclofenac.

There are isolated reports of changes in serum glucose levels in patients with diabetes mellitus, which required changes in the dose of insulin and antidiabetic products.

Release form:
Dicloberl 75 – solution for injection in ampoules of 3 ml (75 mg). There are 5 ampoules in a cardboard box.
Dicloberl 50 – enteric-coated tablets 50 mg. The blister contains 50 or 100 tablets.
Dicloberl-retard – extended-release capsules, 100 mg. Blister contains 10; 20 or 50 capsules.
Dicloberl 50 suppositories - suppositories for rectal administration, 50 mg each. There are 5 or 10 suppositories in a blister.

Storage conditions:
At a temperature not higher than 25°C. In a dark place, inaccessible to children.

Synonyms:
Diclofenac sodium

Dikloberl composition:
Dicloberl 75 (for parenteral administration):

Active ingredients: diclofenac sodium (75 mg).
Inactive ingredients: benzyl alcohol, propylene glycol, sodium hydroxide, mannitol, acetylcysteine, water for injection.

Dicloberl - tablets:

Inactive ingredients: corn starch, methacrylic acid - ethyl acrylate copolymer (1:1), talc, lactose monohydrate, povidone K30, magnesium stearate, sodium carboxymethyl starch, dispersion 30% - dry weight, iron acid pigment yellow (E172), simethicone emulsion, macrogol 400, titanium dioxide (E171), hypromellose, macrogol 6000.

Dikloberl-retard:
Active ingredients: diclofenac sodium (100 mg).
Inactive ingredients: corn starch, oydragit RL 12.5, titanium dioxide, sucrose, shellac, white gelatin, talc.

Dicloberl suppositories:
Active ingredients: diclofenac sodium (50 mg).
Inactive Ingredients: ethanol 96%, solid fat, corn starch, propyl halate.

Additionally:
For diseases of the gastrointestinal tract (Crohn's disease, peptic ulcers, ulcerative colitis, liver diseases), induced porphyria, kidney diseases, arterial hypertension, cardiovascular failure, autoimmune pathologies, individual hypersensitivity to non-steroidal anti-inflammatory drugs, in elderly patients, in the post-operative period, in patients with atopic respiratory diseases, use with caution with constant medical supervision.

After the injection, the patient should be under medical supervision for 1 hour.

The drug can affect (especially with concomitant use of alcohol) the ability to drive vehicles and work with complex dangerous mechanisms. If long-term treatment with dikloberl is necessary, it is necessary to monitor the liver and renal functions, blood electrolyte levels and glucose levels.

Attention!
Before using the medication "Dicloberl" You should consult your doctor.
The instructions are provided for informational purposes only. Dicloberl».